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Journal Article
Research Support, Non-U.S. Gov't
Detection of l-alanylaminopeptidase activity in microorganisms using chromogenic self-immolative enzyme substrates.
Bioorganic & Medicinal Chemistry Letters 2017 May 16
Three potential chromogenic enzymatic probes, each possessing a self-immolative spacer unit, were synthesised for the purpose of detecting l-alanylaminopeptidase activity in microorganisms. An Alizarin-based probe was the most effective, allowing several species to generate strongly coloured colonies in the presence of metal ions.
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