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Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel.
Chemical Communications : Chem Comm 2017 March 10
The novel property of reversible regulation of parallel type G-quadruplexes with moderate temperature changes was discovered in thermoresponsive hydrogels using a universal chiroptical spectrophotometer 1 (UCS-1). This study is the first to report the regulation of the ssDNA steric structure by using a poly(N-isopropylacrylamide) (PNIPAAm) gel.
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