Read by QxMD icon Read

Chemical Communications: Chem Comm

Pratibha Kumari, Sanjay K Verma, Shaikh M Mobin
The morphological divergence of the Endoplasmic Reticulum (ER) during stress is a powerful indicator of several diseases. A new two-photon, non-cytotoxic, fluorescent probe (ERLp) was designed and synthesized in a facile manner for selective tracking of the Endoplasmic Reticulum (ER) with a high Pearson co-localization coefficient (0.91) in live cells and tumor spheroids. Further, ER stress during cell apoptosis and vesicular transport from the ER to the lysosomal compartment were also explored by employing ERLp...
November 16, 2018: Chemical Communications: Chem Comm
Yunbin Hu, Di Wang, Martin Baumgarten, Dieter Schollmeyer, Klaus Müllen, Akimitsu Narita
A spiro-fused hexa-peri-hexabenzocoronene dimer was synthesized, and its physicochemical properties were studied by UV-Vis absorption and emission spectroscopy as well as cyclic voltammetry. Chemical oxidation of SB-HBC afforded its radical cation and dication derivatives, which could be reversibly reduced to the neutral state.
November 16, 2018: Chemical Communications: Chem Comm
Yuxing Huang, Zhuo Xin, Wenlong Yao, Qi Hu, Zhuohua Li, Liuqing Xiao, Bo Yang, Junmin Zhang
The first case of a highly efficient layered double hydroxide (LDH) supported organic visible light photocatalyst is reported and it can catalyze various organic transformations with high efficiency in water under visible light irradiation.
November 16, 2018: Chemical Communications: Chem Comm
Mingdao Zhang, Bao-Hui Zheng, Jing Xu, Na Pan, Jianghua Yu, Mindong Chen, Hui Cao
A new class of 2D fewer-layer π-conjugated conductive metal-organic nanosheets was developed via the Langmuir-Blodgett method, exhibiting ultrahigh mass activity (64.63 A mg-1, 1.7 V vs. RHE) and stability for electrochemical oxygen evolution reactions (OER).
November 16, 2018: Chemical Communications: Chem Comm
Cai-Cai Zhang, Ying-Ming Zhang, Yu Liu
Lamellar and helical supramolecular assemblies were constructed using cucurbiturils and a naphthalenediimide derivative. More interestingly, the formation of the lamellar assembly could be reversibly photocontrolled via competitive binding with α-cyclodextrin and water-soluble azobenzene.
November 16, 2018: Chemical Communications: Chem Comm
Yujie Ma, Jing Li, Jianxun Ye, Delong Liu, Wanbin Zhang
Chiral chromanols and their derivatives have been synthesized via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones in high yields, >20 : 1 drs and with up to 99.9% ee. Control experiments show that the reaction undergoes two sequential asymmetric hydrogenation steps of the C[double bond, length as m-dash]C and C[double bond, length as m-dash]O double bonds. The reaction could be performed on a gram-scale with a relatively low catalyst loading (up to 1000 S/C), and the resulting products can be transformed to several biologically active compounds...
November 16, 2018: Chemical Communications: Chem Comm
Weiwei Feng, Ming Jin, Kui Yang, Yuxin Pei, Zhichao Pei
Supramolecular delivery systems (SDSs) fabricated via molecular assembly, which conveniently allow integration of multiple functions in a single system and structural diversity of systems, are a very active research area due to their enormous potential in biomedical applications, including drug delivery, cell imaging, diagnosis, and release monitoring. Pillararenes, a novel type of macrocyclic molecule, are gaining increasing interest as an important component in the construction of SDSs due to their unique structural and chemical properties...
November 16, 2018: Chemical Communications: Chem Comm
Efe Ilker, Melihat Madran, Mine Konuk, Sondan Durukanoğlu
The growth and shape stability of bi-metallic cubic Cu-Ni nanoparticles are studied using atomic-level simulations. Cubic nano-crystals coated with an ultra-thin Cu layer can be readily obtained when Ni cubic nanoparticles are used as the seeds. At elevated temperatures, the Cu seed with extending Ni branches preserves its shape compared to the Ni seed with extending Cu branches.
November 16, 2018: Chemical Communications: Chem Comm
Hitomi Hayashibara, Xiaohua Hou, Kotohiro Nomura
Highly active catalysts for the ring-opening metathesis polymerization (ROMP) of cyclic olefins (norbornene, cyclopentene, cycloheptene) can be generated in situ by premixing V(CHSiMe3)(NC6F5)(O-2,6-iPr2C6H3)(PMe3)2 (1) with 1.0 equiv. of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].
November 16, 2018: Chemical Communications: Chem Comm
Song Liu, Tao Zhang, Lei Zhu, Kangbao Zhong, Jianxian Gong, Zhen Yang, Ruopeng Bai, Yu Lan
Theoretical calculations have been performed to investigate the mechanism and stereoselectivity of rhodium-catalysed intramolecular [3+2] cycloaddition for construction of a substituted hexahydropentalene complex. A new C-C bond cleavage mechanism, retro-Aldol-type, is proposed and verified for this Rh-catalysed [3+2] cycloaddition reaction.
November 16, 2018: Chemical Communications: Chem Comm
Imtiaz Begum, Gregor Schnakenburg, Zsolt Kelemen, László Nyulászi, René T Boeré, Rainer Streubel
A new sulfur-enriched tricyclic 1,4-diphosphinine (2) was synthesized and novel reactivity studies on the phosphorus heterocycle were performed: a weak anionic nucleophile (KHMDS) adds selectively thus forming a stable anionic 1,4-diphosphinine derivative (3b) which was fully characterized. The substitution potential of 3b was demonstrated using Ph2PCl to give 4b, while oxidation of 3b using elemental iodine furnished cleanly the P-P coupling product 5.
November 16, 2018: Chemical Communications: Chem Comm
Bin Lei, Jun Yang, Zhixin Xu, Shasha Su, Dong Wang, Jinhua Jiang, Jing Feng
The practical application of high energy lithium-sulfur batteries is still limited by unstable lithium anodes and the shuttle effect of polysulfides. Herein, a gel-like electrolyte induced by fumed alumina is proposed for dendrite-free Li deposition, lower over-potential and better cycle stability. Li-S@pPAN cells with the proposed electrolyte exhibit outstanding cycle stability and rate performance with capacity retentions of 95.1% after 300 cycles and 76.5% at 10C against 1C, respectively.
November 16, 2018: Chemical Communications: Chem Comm
Yuan-Jie Cheng, Rui Wang, Shan Wang, Xiao-Juan Xi, Lu-Fang Ma, Shuang-Quan Zang
We encapsulated anionic [Mo3S13]2- clusters in cationic COFs (EB-COF) to obtain the novel composite photocatalytic material Mo3S13@EB-COF. Comprehensive studies indicated that the Mo3S13@EB-COF was the product of a successful conversion of a homogeneous to a heterogeneous catalyst, and exhibited excellent stability and recyclability as well as a remarkable photocatalytic hydrogen evolution rate of 13 215 μmol g-1 h-1 under visible-light irradiation over the course of 18 hours.
November 16, 2018: Chemical Communications: Chem Comm
Anna Kocyła, Artur Krężel
Considering the complex biological quandaries of the tightly woven networks of biological macromolecules, we present an optimized zinc clasp-based toolset from the CD4 co-receptor and Lck protein tyrosine kinase complex for selective, tight and fully reversible protein heterodimerization (log K12 = 18.6). We demonstrated its utility on CD4-tagged proteins with capture from bacterial lysate and constructed molecular baits using a new small-molecule tether.
November 16, 2018: Chemical Communications: Chem Comm
Dongxu He, Weidong Xue, Zheling Li, Alexander J Marsden, Eric Prestat, Wencheng Hu, Rui Zhao, Mark A Bissett
A facile molten-salt (MS) route for the scalable synthesis of free-standing, long-range oriented and corrugated graphene-like sheets from a copper phthalocyanine (CuPc) precursor is reported. Their unique arrangement and transformation behavior in molten potassium chloride (KCl) play a key role in promoting the successful synthesis of the anisotropic nanostructure.
November 16, 2018: Chemical Communications: Chem Comm
Stefania Porcu, Alberto Luridiana, Alberto Martis, Angelo Frongia, Giorgia Sarais, David J Aitken, Thomas Boddaert, Regis Guillot, Francesco Secci
A general strategy for the synthesis of arylthio cyclopropyl carbaldehydes and ketones via a Brønsted acid catalyzed arylthiol addition/ring contraction reaction sequence has been exploited. The procedure led to a wide panel of cyclopropyl carbaldehydes in generally high yields and with broad substrate scope. Mechanistic aspects and synthetic applications of this procedure were investigated.
November 16, 2018: Chemical Communications: Chem Comm
Min Jung Chang, Kyutae Kim, Kyun Seob Park, Ji Su Kang, Chang Su Lim, Hwan Myung Kim, Chulhun Kang, Min Hee Lee
We developed a fluorescent pH probe (1) capable of two-photon excitation and far-visible-emission based on FRET, composed of naphthalimide-piperazine-rhodamine. It exhibited a pH-dependent reversible and fast ratiometric fluorescence change in the rhodamine emission. Probe 1 was applied to image the pH perturbations of mitochondria in living cells and tissues.
November 15, 2018: Chemical Communications: Chem Comm
Guoqiang Dong, Yang Liu, Ying Wu, Jie Tu, Shuqiang Chen, Na Liu, Chunquan Sheng
Targeting secreted aspartic protease 2 (SAP2), a kind of virulence factor, represents a new strategy for antifungal drug discovery. In this report, the first-generation of small molecule SAP2 inhibitors was rationally designed and optimized using a structure-based approach. In particular, inhibitor 23h was highly potent and selective and showed good antifungal potency for the treatment of resistant Candida albicans infections.
November 15, 2018: Chemical Communications: Chem Comm
Yi-Nan Lu, Jin-Ping Lan, Yu-Jia Mao, Ye-Xin Wang, Guang-Jian Mei, Feng Shi
The first de novo construction of enantioenriched dihydroquinazolinones via an intermolecular strategy has been established. This approach also represents the first catalytic asymmetric [4+2] cycloaddition of vinyl benzoxazinanones with sulfonyl isocyanates, which afforded chiral dihydroquinazolinones in high yields and excellent enantioselectivities (up to 98% yield, 99 : 1 er). This reaction not only confronts the great challenge in de novo construction of enantioenriched dihydroquinazolinone skeletons, but also advances the chemistry of decarboxylative cycloadditions involving vinyl benzoxazinanones...
November 15, 2018: Chemical Communications: Chem Comm
André Hermannsdorfer, Douglas W Stephan, Matthias Driess
A dicationic bis(NHC)-stabilised silyldiium complex, [bis(NHC)-SiPh2]2+ (72+) (bis(NHC) = [CH2(NC3H2NDipp)2], Dipp = 2,6-iPr2C6H3), was synthesised for the first time. It reacts with sodium phosphaethynolate (NaOCP) as a source of monoanionic phosphorus to give the P-insertion product [bis(NHC)-PSiPh2]+ (8+). The latter comprises a seven-membered heterocycle containing a Si-P moiety which can easily be desilylated when exposed to dichlorophosphanes as exemplified by the synthesis of the diphosphanide cations [bis(NHC)-PPCy]+ (9+) and [bis(NHC)-PPPh]+ (10+)...
November 15, 2018: Chemical Communications: Chem Comm
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"