Read by QxMD icon Read

Chemical Communications: Chem Comm

David James Martin, Donato Decarolis, Yaroslav I Odarchenko, Jennifer J Herbert, Thomas Arnold, Jonathan Rawle, Chris Nicklin, Hans-Gerd Boyen, Andrew M Beale
Periodically arranged, monodisperse gold nanoparticles supported on flat silicon substrates were studied for the hydrogenation of 1,3-butadiene under operando conditions using Grazing Incidence Small- and Wide-Angle X-ray Scattering (GISAXS/GIWAXS). It was found that the composition and shape of the nanoparticles depends very much on the chemical environment; the particles are shown to be dynamic, undergoing reversible size and shape change particularly during catalytic reaction, highlighting a dynamism often not observed in traditional studies...
April 25, 2017: Chemical Communications: Chem Comm
Lindsay E Evans, Keith Jones, Matthew D Cheeseman
Proteins typically carry out their biological functions as multi-protein complexes, which can significantly affect the affinity of small-molecule inhibitors. HSP70 is an important target in oncology, so to study its chemical biology and the drug discovery potential of the HSP70/BAG1 complex, we designed a high-affinity non-nucleotide fluorescence polarisation probe.
April 25, 2017: Chemical Communications: Chem Comm
James A Clulow, Elisabeth M Storck, Thomas Lanyon-Hogg, Karunakaran A Kalesh, Lyn H Jones, Edward W Tate
Sulforaphane is a small molecule isothiocyanate which exhibits anticancer potential, yet its biological targets remain poorly understood. Here we employ a competition-based chemical proteomics strategy to profile sulforaphane's targets and identify over 500 targets along with their relative affinities. These targets provide a new set of mediators for sulforaphane's bioactivity, and aid understanding of its complex mode of action.
April 25, 2017: Chemical Communications: Chem Comm
Daniel C Hannah, Gopalakrishnan Sai Gautam, Pieremanuele Canepa, Ziqin Rong, Gerbrand Ceder
We propose that Ti-containing post-spinels may offer a practically-accessible route to fast multivalent ion diffusion in close-packed oxide lattices, with the caveat that substantial thermodynamic driving forces for conversion reactions exist.
April 25, 2017: Chemical Communications: Chem Comm
Yuliia Vyborna, Mykhailo Vybornyi, Robert Häner
The synthesis, characterization and functionalization of DNA-grafted supramolecular polymers are described. Cargo loading of the helical supramolecular assemblies with gold nanoparticles is demonstrated.
April 25, 2017: Chemical Communications: Chem Comm
Hua-Shang Rao, Bai-Xue Chen, Xu-Dong Wang, Dai-Bin Kuang, Cheng-Yong Su
Nowadays, obtaining a thin and large-area perovskite single-crystal (SC) is still challenging. Herein, we report a novel strategy to prepare a laminar MAPbBr3 SC with a controllable thickness of 16 μm and a size of 6 × 8 mm. Additionally, the SC solar cell achieves an intriguing efficiency of 7.11% with an impressive stability, maintaining 93% initial PCE after aging for 1000 h.
April 25, 2017: Chemical Communications: Chem Comm
Jiangyan Jing, Xiaohong Huo, Jiefeng Shen, Jingke Fu, Qinghua Meng, Wanbin Zhang
Allylic alcohols and allylic amines were directly utilized in a Pd-catalyzed hydrogen-bond-activated allylic amination under mild reaction conditions in the absence of any additives. The cooperative action of a Pd-catalyst and a hydrogen-bonding solvent is most likely responsible for its high reactivity. The catalytic system is compatible with a variety of functional groups and can be used to prepare a wide range of linear allylic amines in good to excellent yields. Furthermore, this methodology can be easily applied to the one-step synthesis of two drugs, cinnarizine and naftifine, on a gram scale...
April 25, 2017: Chemical Communications: Chem Comm
Hongyuan Zhang, Yanzhao Nie, Xinmei Zhi, Haifeng Du, Jing Yang
In this communication, we presented a novel strategy to control the ROP of α-amino acid N-carboxy-anhydrides using the concept of frustrated Lewis pairs (FLPs). An FLP intermediate containing an interaction between the bulky borane Lewis acid and the amine groups of the propagation chain end is essential to accomplish the polypeptide synthesis with well-defined structures under mild conditions.
April 25, 2017: Chemical Communications: Chem Comm
Abir Goswami, Indrajit Paul, Michael Schmittel
The fusion of two homoleptic complexes quantitatively created a novel three-component nanorotor. The intra-supramolecular rotational dynamics leads to a rapid exchange (k298 = 24.0 ± 2.5 kHz) of two degenerate Npy → ZnPor interactions. Metal exchange at the remote HETTAP complexation site provided a faster nanorotor (k298 = 34.0 ± 3.0 kHz).
April 25, 2017: Chemical Communications: Chem Comm
Carrie L McCarthy, Richard L Brutchey
Macroelectronics is a major focus in electronics research and is driven by large area applications such as flat panel displays and thin film solar cells. Innovations for these technologies, such as flexible substrates and mass production, will require efficient and affordable semiconductor processing. Low-temperature solution processing offers mild deposition methods, inexpensive processing equipment, and the possibility of high-throughput processing. In recent years, the discovery that binary "alkahest" mixtures of ethylenediamine and short chain thiols possess the ability to dissolve bulk inorganic materials to yield molecular inks has lead to the wide study of such systems and the straightforward recovery of phase pure crystalline chalcogenide thin films upon solution processing and mild annealing of the inks...
April 25, 2017: Chemical Communications: Chem Comm
A Llevot, B Monney, A Sehlinger, S Behrens, M A R Meier
Palladium nanoparticles stabilized by poly(vinylpyrrolidone) catalyze Tsuji-Trost allylations in water with very high turnover numbers. The di-allylation of methylene active compounds and the allylation of bio-based phenols was performed in high yield. The allylation of lignin showed a high selectivity towards the phenolic OH groups.
April 25, 2017: Chemical Communications: Chem Comm
Shumeng Wang, Baohua Zhang, Yang Wang, Junqiao Ding, Zhiyuan Xie, Lixiang Wang
Self-host Ir dendrimers have been adopted as the nondoped emitting layer for the successful construction of multilayer green phosphorescent organic light-emitting diodes (PhOLEDs) prepared via layer-by-layer solution processing with orthogonal solvents. Unlike previous doped systems, the risk of small-molecular-phosphor redissolution by alcohols and the resultant serious batch-to-batch variation can be eliminated. Consequently, a record-high external quantum efficiency of 21.2% together with good reproducibility is achieved for the green-emitting Ir dendrimer G2, which displays sufficient alcohol resistance owing to the effective encapsulation from the second generation dendritic wedge...
April 24, 2017: Chemical Communications: Chem Comm
Yu-Xin Li, Shang-Ju Li, Peng-Fei Yan, Xin-Yu Wang, Xu Yao, Guang-Hui An, Guang-Ming Li
The white-light emission of a triple-component lanthanide coordination polymer turns to blue and red upon adding Mn(2+) and Ag(+) ions, respectively.
April 24, 2017: Chemical Communications: Chem Comm
Subhrajit Rout, Arko Das, Vinod K Singh
A highly diastereo- and enantioselective vinylogous Mukaiyama-Michael reaction of silyloxyfurans with α,β-unsaturated 2-acyl imidazoles catalyzed by either chiral Sc(iii) or Er(iii) complexes of a pybox ligand has been reported. The enantioenriched γ-butenolides formed in the reaction were further transformed into highly functionalized γ-lactones found as important structural frameworks in a wide range of biologically active natural products.
April 24, 2017: Chemical Communications: Chem Comm
Yuling Sun, Yong Tao, Qingchen Cao, Yanbin Huang
Foscarnet sodium is an antiviral drug for the treatment of CMV retinitis, currently in the form of twice-weekly intravitreal injection. Here we developed foscarnet calcium microcrystals as the drug depot, and using the rabbit model we demonstrated that the injected microcrystals maintained a therapeutically relevant drug concentration in the vitreous for more than 3 months.
April 24, 2017: Chemical Communications: Chem Comm
B Fortuni, Y Fujita, M Ricci, T Inose, R Aubert, G Lu, J A Hutchison, J Hofkens, L Latterini, H Uji-I
A novel one-step in situ synthesis of gold nanostars (AuNSs) on a pre-cured polydimethylsiloxane (PDMS) film is proposed for the fabrication of highly sensitive surface-enhanced Raman scattering (SERS) substrates. Plasmonic activity of the substrates was investigated by collecting SERS maps of 4-mercaptobenzoic acid (4-MBA). The applicability of these flexible substrates is further demonstrated by SERS-based pesticide detection on fruit skin.
April 24, 2017: Chemical Communications: Chem Comm
Saskia Spitzer, Atena Rastgoo-Lahrood, Klaus Macknapp, Viktoria Ritter, Stefan Sotier, Wolfgang M Heckl, Markus Lackinger
A protocol is proposed for the solvent-free on-surface synthesis of covalent organic framework monolayers by condensation of diboronic acids. Monomers are vapor-deposited and water is used for equilibrium regulation. Samples are characterized on progressively smaller length scales by light microscopy, Scanning Electron Microscopy, and Scanning Tunneling Microscopy.
April 24, 2017: Chemical Communications: Chem Comm
Long Wang, Senwang Zhang, Yasuharu Hasegawa, Constantin G Daniliuc, Gerald Kehr, Gerhard Erker
Twofold hydroboration of the bulky Mes*P(vinyl)2 phosphane with Piers' borane [HB(C6F5)2] followed by C6F5/H exchange with 9-BBN generated a reactive P/B/BH FLP structure that cleanly reduced carbon monoxide at the trifunctional frustrated Lewis pair framework to the [B]-formyl stage.
April 24, 2017: Chemical Communications: Chem Comm
Susovan Jana, Animesh Roy, Salvatore D Lepore
The unique reactivity of γ-silyl allenyl esters is described. Taking advantage of the silyl group as a fluoride acceptor, these allenoates readily underwent addition to a variety of electrophiles to selectively yield products with all-carbon quaternary centers or allenoate dicarbinols. These dicarbinols were subsequently converted to novel highly substituted 6-hydro-2-pyrones.
April 24, 2017: Chemical Communications: Chem Comm
Veeranjaneyulu Lanke, Kandikere Ramaiah Prabhu
The C4-aminated indole scaffold is frequently encountered in several natural products and biologically active compounds. Herein we disclose a simple and short synthetic route for the amidation of indoles at the C4 position by employing an aldehyde as a directing group and Ir(iii) as a catalyst. This strategy offers high selectivity for the C4-amidation of unprotected and protected indoles. A simple deprotection of the tosyl group leads to the formation of C4-amino indole derivatives, which are useful synthons for synthesizing natural products in the teleocidin family...
April 24, 2017: Chemical Communications: Chem Comm
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"