We have located links that may give you full text access.
The role of ancillary tests in the evaluation and management of patients with negative and non-diagnostic pancreatic cyst aspirates.
Diagnostic Cytopathology 2017 April
BACKGROUND: Fine needle aspiration of pancreatic cystic lesions has its limitations as the cytology is often paucicellular to acellular. This study reports on the value of ancillary tests, amylase and carcinoembryonic, in the evaluation and management of patients with negative and non-diagnostic pancreatic cysts.
METHODS: From January 1, 2010 through December 31, 2015, the Cytopathology Laboratory processed 119 pancreatic cyst aspirates of which 51(43%) were negative and 52(44%) were non-diagnostic and form the basis of this study. The 103 patients, 66 men and 37 women underwent endoscopic ultrasound with fine needle aspiration and biochemical and biomarker analysis; amylase and carcinoembryonic antigen, of cyst contents. In this study, the cytologic findings were interpreted independent of the cyst fluid analysis.
RESULTS: Of the 51 patients with negative pancreatic cyst aspirates, combined endoscopic ultrasound/cytology/cyst fluid analysis findings were compatible with 37 (72%) pseudocysts, 11 (22%) serous cystadenomas, and 3 (6%) intraductal papillary mucinous neoplasms. Of the 52 patients with non-diagnostic pancreatic cyst aspirates, combined endoscopic ultrasound/cyst fluid analysis findings were compatible with 17 (33%) pseudocysts, 17 (33%) serous cystadenomas, 14 (27%) intraductal papillary mucinous neoplasms, and 4 (7%) mucinous cystic neoplasms. Eight patients underwent surgical resection and the remaining 95 patients were managed medically with repeat imaging.
CONCLUSION: Ancillary tests are of added benefit in the evaluation and management of patients with negative and non-diagnostic pancreatic cyst aspirates. Diagn. Cytopathol. 2017;45:303-307. © 2016 Wiley Periodicals, Inc.
METHODS: From January 1, 2010 through December 31, 2015, the Cytopathology Laboratory processed 119 pancreatic cyst aspirates of which 51(43%) were negative and 52(44%) were non-diagnostic and form the basis of this study. The 103 patients, 66 men and 37 women underwent endoscopic ultrasound with fine needle aspiration and biochemical and biomarker analysis; amylase and carcinoembryonic antigen, of cyst contents. In this study, the cytologic findings were interpreted independent of the cyst fluid analysis.
RESULTS: Of the 51 patients with negative pancreatic cyst aspirates, combined endoscopic ultrasound/cytology/cyst fluid analysis findings were compatible with 37 (72%) pseudocysts, 11 (22%) serous cystadenomas, and 3 (6%) intraductal papillary mucinous neoplasms. Of the 52 patients with non-diagnostic pancreatic cyst aspirates, combined endoscopic ultrasound/cyst fluid analysis findings were compatible with 17 (33%) pseudocysts, 17 (33%) serous cystadenomas, 14 (27%) intraductal papillary mucinous neoplasms, and 4 (7%) mucinous cystic neoplasms. Eight patients underwent surgical resection and the remaining 95 patients were managed medically with repeat imaging.
CONCLUSION: Ancillary tests are of added benefit in the evaluation and management of patients with negative and non-diagnostic pancreatic cyst aspirates. Diagn. Cytopathol. 2017;45:303-307. © 2016 Wiley Periodicals, Inc.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app