Read by QxMD icon Read

Diagnostic Cytopathology

Nidhi Goel, Venus Khanna, Dileep Kumar Jain, Vivek Gupta
Fine-needle aspiration cytology (FNAC) is an important diagnostic tool which is replacing biopsy for the diagnosis of subcutaneous nodules. We present a case of 75 years old female with right sided multinodular lateral inguinal swelling since 2 years, without any clinical features of arthritis. FNAC of the lesion revealed negatively birefringent, long needle shaped monosodium urate crystals in the background of amorphous granular debris. Further investigations revealed high serum uric acid levels (9.36 mg/dL) and a confirmed diagnosis of gouty tophus was made...
June 7, 2018: Diagnostic Cytopathology
Elise Nguyen, Manando Nakasaki, Thomas K Lee, Di Lu
Paragangliomas are rare neoplasms that arise from the chromaffin cells of the autonomic nervous system. Although paragangliomas can occur anywhere paraganglia are present, they tend to occur in the head, neck, and retroperitoneum. Rarely, paragangliomas can occur in the peripancreatic area and present as a pancreatic mass, creating a diagnostic challenge for the clinician, radiologist, and pathologist. Here, we present a case of a 70-year-old woman with history of breast carcinoma who presented with chronic constipation, early satiety, and an abdominal mass...
June 7, 2018: Diagnostic Cytopathology
Rafael Martínez-Girón, Cristina Martínez-Torre, Santiago Martínez-Torre
No abstract text is available yet for this article.
May 16, 2018: Diagnostic Cytopathology
Jie-Yang Jhuang, Wei-Yu Chen, Shih-Sung Chuang
Histiocytic sarcoma (HS) is a rare malignant neoplasm showing morphological and immunophenotypic features of mature tissue histiocytes. As HS may mimic non-Hodgkin lymphoma (NHL) pathologically, before the era of immunohistochemistry, many previously reported cases were misdiagnosed NHL. Up to date, there are only a few reports delineating the cytological features in fine-needle aspiration or bronchoalveolar lavage, but not in the effusion fluid yet. Herein, we report the case of a 61-year-old male with a mediastinal tumor presenting with malignant pleural effusion...
May 13, 2018: Diagnostic Cytopathology
Tracey Stevenson, Manish Powari, Christopher Bowles
OBJECTIVE: Endobronchial ultrasound fine needle aspiration (EBUS FNA) is a well-established procedure for the diagnosis and staging of lung cancer. We review our provision of this service at the Royal Devon and Exeter NHS Foundation Trust and the role of rapid onsite evaluation (ROSE) with the increasing demand for molecular markers in this era of personalized medicine. METHODS: A review of the changes in the Endoscopy clinic over the 7 years from the introduction of EBUS at the end of 2010 until 2017 was carried out...
May 13, 2018: Diagnostic Cytopathology
Dilip K Das, Smiley A George, Tareq Mohammad, Bency John, Sara S George, Abdulla I Behbehani
Carcinoma associated with thyroglossal duct cyst (TDC) is extremely rare and when it occurs it is invariably papillary carcinoma. A 36-year-old man presented with a midline swelling in the upper part of neck, which was a cystic lesion with multiple septae in ultrasonogram, indicating a thyroglossal duct cyst. The CT scan findings also corroborated the ultrasound report. Fine needle aspiration (FNA) smears showed hemosiderin laden cyst macrophages and occasional papillary cluster of neoplastic cells with central psammoma body and rare intranuclear cytoplasmic inclusions...
May 8, 2018: Diagnostic Cytopathology
Mohamed M Abdelfatah, Ahmed Hamed, Nicholas J Koutlas, F Zahra Aly
INTRODUCTION: Two new systems with a novel tip (Procore™ and SharkCore™) have been introduced for ultrasound-guided fine needle biopsy (US-FNB). Direct comparison of the diagnostic yield of these needles in the evaluation of pancreatic lesions is currently under investigation. This study aims to compare the diagnostic and cellular yields of the two needle systems. METHODS: Consecutive patients with upper gastrointestinal lesions undergoing EUS-FNB using 22 gauge Procore™ (reverse bevel) or SharkCore™ (fork-tip) needles were included in the study...
May 7, 2018: Diagnostic Cytopathology
Smita Singh, Mitali Swain, Shailaja Shukla, Ram Chander
Molluscum contagiosum (MC) is most frequently a self-limiting benign viral skin disease. Transmitted by direct skin contact, it is characterized by flesh-colored, dome-shaped, umbilicated lesions. Diagnosis of MC is often done clinically, but when needed, biopsy can be performed, in which characteristic Henderson-Patterson bodies, representing intracytoplasmic assemblies of the virus, are pathognomonic. Atypical presentations of MC are rare in immunocompetent individuals and are challenging to diagnose. We report a case of giant MC, presenting as an ulcero-proliferative growth, in neck of an 8-month-old female child...
May 7, 2018: Diagnostic Cytopathology
Justin E Caron, Yong Ying, Qin Ye, Lirong Cheng, Jian Yu Rao
International telecytology can improve patient care by increasing access to regional and international expertise in cytopathology. The majority of international telecytology studies published to date have been based on static telepathology platforms. Overall concordance rates for these studies ranged from 71% to 93%. This is comparable to the concordance rates published for other studies comparing diagnoses made by digital still images to reference glass slides, which vary from 80% to 95%. Static telepathology systems are relatively cheap and easy to use, and have the potential to increase access to international experts in developing countries with limited resources...
May 4, 2018: Diagnostic Cytopathology
Alia Gupta, Mark Micale, Kurt D Bernacki
Melanotic Xp11 translocation renal cancer is a rare category of MiTF/TFE3 neoplasms morphologically resembling Xp11 translocation renal cell carcinoma, Xp11 translocation perivascular epithelioid cell tumor, and melanoma. The diagnosis requires demonstration of TFE3 gene rearrangement, by either fluorescence in situ hybridization (FISH) at the Xp11.2 locus or by TFE3 immunohistochemistry. As cytology smears can be useful adjuncts in cytogenetic and molecular testing, we demonstrate TFE3 rearrangement by FISH analysis on cytologic smears in melanotic Xp11 translocation renal cancer...
May 3, 2018: Diagnostic Cytopathology
(no author information available yet)
No abstract text is available yet for this article.
July 2018: Diagnostic Cytopathology
Keishin Sunagawa, Michiko Yagoshi, Atsuko Suzuki, Toshimi Seki, Shigeki Nakamura, Yoshitsugu Miyazaki, Tomohiro Nakayama, Shu Hashimoto, Masahiko Sugitani
No abstract text is available yet for this article.
July 2018: Diagnostic Cytopathology
Myrto Costopoulos, Madalina Uzunov, Dominique Bories, Frederic Charlotte, Karim Maloum, Michel Arock
No abstract text is available yet for this article.
July 2018: Diagnostic Cytopathology
Miguel Dario Cantu, Abha Goyal
No abstract text is available yet for this article.
July 2018: Diagnostic Cytopathology
Evelyn Carolina Polanco Jacome, Jennifer Maerki, Karen Chau, Meredith Akerman, Sujata Sajjan, Melissa Klein, Cecilia Gimenez, Alice Laser, Kasturi Das
BACKGROUND: Bethesda guidelines do not require presence of transformation zone (TZ) for a cervical Pap test to be deemed adequate. However, clinicians are concerned with specimens that are reported to lack TZ. METHODS: We analyzed 566 ThinPrep cases reported as negative for intraepithelial lesion or malignancy (NILM) with no cervical abnormality detected in previous 4 years (2007-2011). These cases were divided into two cohorts; those with TZ (ETZ) and those without TZ (NTZ)...
July 2018: Diagnostic Cytopathology
Malesiba Mampotoko Selepe, Abraham Christoffel van Wyk, Kim Gilberte Pauline Hoek, Yvonne Prince, Paul David van Helden, Robin Mark Warren, Colleen Anne Wright
BACKGROUND: The rapid diagnosis of extrapulmonary tuberculosis in children remains challenging. The presence of enlarged lymph nodes provides an opportunity to obtain diagnostic material through fine needle aspiration biopsy (FNAB). Mycobacterial culture, traditionally the reference standard, has a slow turnaround time and PCR-based methods are not widely available in developing countries. Direct visualization of mycobacteria on microscopy can be a rapid method to confirm the diagnosis...
July 2018: Diagnostic Cytopathology
Paul A Elgert, Melissa Yee-Chang, Aylin Simsir
OBJECTIVE: Cytomegalovirus (CMV) is a ubiquitous infection typically affecting over 50% of the US population by age 40. We report 8 cases of CMV infections detected in cervical cancer screening tests, the largest series of cases thus far reported in gynecologic cytology specimens. METHODS: A retrospective review of our pathology archival computer database was performed from January 1, 1994 through December 31, 2016 for CMV infections reported in cervical cytology specimens...
July 2018: Diagnostic Cytopathology
Amir Hossein Jafarian, Aida Tasbandi, Nema Mohamadian Roshan
BACKGROUND: The aim of this study is to investigate and compare the results of digital image analysis in pleural effusion cytology samples with conventional modalities. MATERIALS AND METHODS: In this cross-sectional study, 53 pleural fluid cytology smears from Qaem hospital pathology department, located in Mashhad, Iran were investigated. Prior to digital analysis, all specimens were evaluated by two pathologists and categorized into three groups as: benign, suspicious, and malignant...
July 2018: Diagnostic Cytopathology
Priya Pathak, Pooja Sharma, Aditi Daga, Sonal Sharma
INTRODUCTION: Fine needle aspiration (FNA) is routinely used in triaging thyroid lesions in adults. However, role of FNA in pediatric thyroid lesions is less studied. AIM AND OBJECTIVE: To study the cyto-morphologic spectrum of thyroid lesions in pediatric population. MATERIALS AND METHODS: A retrospective analysis (duration-6 years) of thyroid FNA for patients who were 18 years or younger was conducted. The aspirates were classified according to the Bethesda System for Reporting Cytopathology...
July 2018: Diagnostic Cytopathology
Joseph A Chorny, Teresa C Frye, Beth L Fisher, Carol L Remmers
BACKGROUND: The primary high-risk human papillomavirus (hrHPV) assays in the United States are the cobas (Roche) and the Aptima (Hologic). The cobas assay detects hrHPV by DNA analysis while the Aptima detects messenger RNA (mRNA) oncogenic transcripts. As the Aptima assay identifies oncogenic expression, it should have a lower rate of hrHPV and genotype detection. METHODS: The Kaiser Permanente Regional Reference Laboratory in Denver, Colorado changed its hrHPV assay from the cobas to the Aptima assay...
July 2018: Diagnostic Cytopathology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"