Anti-Müllerian Hormone Levels in Chinese Women Younger Than 30 Years and 30 Years or Older and Correlated Biochemical Indices.

Importance: Anti-müllerian hormone (AMH) is considered an important marker of ovarian reserve; however, the exact function of AMH has yet to be determined.

Objective: Our purpose was to investigate factors correlated with AMH levels in Chinese women.

Evidence Acquisition: Healthy women were divided into 2 groups: aged younger than 30 years and 30 years or older. Anti-müllerian hormone levels and biochemical indices were compared between the groups.

Results: Eighty women younger than 30 and 29 women 30 years or older were included. The mean AMH level in women younger than 30 years was 8.2 ± 4.4 ng/mL (range, 0.1-17.2 ng/mL), and in those 30 years or older was 5.2 ± 4.3 ng/mL (range, 0.1-13.3 ng/mL). Half of women younger than 30 years had an AMH level above a median of 8.0 ng/mL (interquartile range, 4.9-11.2 ng/mL), whereas the median in those 30 years or older was 4.6 ng/mL (interquartile range, 1.3-8.5 ng/mL). In women younger than 30 years, calcium was positively correlated (P = 0.014) and sex hormone-binding globulin (SHBG) was negatively correlated with AMH (P < 0.001). No correlations of calcium and SHBG with AMH were found in women 30 years or older, but a positive correlation between triglycerides and testosterone and AMH was noted (P = 0.020 and P = 0.007, respectively).

Conclusions and Relevance: Anti-müllerian hormone levels are positively or negatively correlated with testosterone, calcium, SHBG, and triglycerides in Chinese women.