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Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients.
Clinical Imaging 2017 March
OBJECTIVE: To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications.
METHODS: 57 patients with focally increased FDG activity in bones and a definite follow up were included.
RESULTS: 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%.
CONCLUSION: Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.
METHODS: 57 patients with focally increased FDG activity in bones and a definite follow up were included.
RESULTS: 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%.
CONCLUSION: Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.
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