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Clinical and Molecular Characterization of Invasive Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Infections in Korean Hospitals.

Eu Suk Kim, In-Gyu Bae, Jeong Eun Cho, Yun Jung Choi, Il-Hwan Kim, Gi-Su Kang, Hye-yun Sin, Kyoung-Ho Song, Chulmin Park, Dong-Gun Lee, Moonsuk Kim, Kyoung Un Park, Hong Bin Kim
Journal of Clinical Microbiology 2016 March
Invasive heteroresistant vancomycin-intermediate Staphylococcus aureus (h-VISA) isolates were identified and characterized in 10 Korean hospitals from July 2009 to June 2011. The prevalence of h-VISA infections was 3.3% (42/1,289). Most (41/42) were health care-associated infections caused by strains belonging to sequence type 5. Cases of persistent bacteremia were frequent (17/42), and 30-day mortality was high (16/40).

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