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Journal Article
Research Support, Non-U.S. Gov't
Functional promoter polymorphisms of the receptor for advanced glycation end products in children and adolescents with type 1 diabetes.
Molecular and Cellular Probes 2015 December
RAGE promoter polymorphisms are associated with increases in RAGE expression. A case-control association study was conducted involving a Euro-Brazilian population of children and adolescents with type 1 diabetes (n = 90) and healthy controls (n = 105), which were matched by sex and age. Genotyping by PCR-RFLP the -429T>C (rs1800625), -374T>A (rs1800624), and 63 bp deletion/insertion (-407 to -345 bp) showed no significant differences (P > 0.05) between the groups.
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