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[132-POS]: Factors associated with vaginal delivery in hypertensive and normotensive pregnant women submitted to labor induction with misoprostol: A cohort study.
Pregnancy Hypertension 2015 January
OBJECTIVES: To determine the factors associated with vaginal delivery in hypertensive and normotensive pregnant women submitted to induction of labor with misoprostol.
METHODS: We conducted a cohort study, with pregnant women submitted to induction of labor with misoprostol, evaluating normotensive and hypertensive gestation. All pregnancies had a live fetus. The main outcomes analyzed were: age, parity, number of pregnancies, gestational age, index of amniotic fluid, Bishop score, fetus weight estimated by ultrasound, premature rupture of membranes, diabetes, peridural analgesia, presence of meconium in the amniotic liquid, cervical modifications, time of induction, time of labor and time between induction and labor, need of oxytocin, route of misoprostol administration and size of cervix by ultrasound. For statistical analysis we used the chi-square test or Fisher's exact test, as appropriate, at a significance level of 5%. We also calculated the risk ratio (RR) and its confidence interval 95% (95% CI).
RESULTS: We evaluated 410 pregnant women submitted to induction of labor with misoprostol, 227 in normotensive and 183 in hypertensive gestation. The frequency of vaginal delivery was similar in both groups, with 61,2% in normotensive pregnant women and 57.4% in hypertensive (p=0.43). The risk factors associated with vaginal delivery in both women were, respectively: Bishop score ⩾4 (OR=1.87; 95%CI: 1.06-3.29; p=0.03) and (OR=2.31; 95%CI: 1.25-4.28; p=0.008) and parity ⩾1 (OR=4.36; 95%CI: 2.16-8.80; p<0.0001) and (OR=2.61; 95%CI: 1.36-5.04; p=0.004).
CONCLUSIONS: The main factors associated with progression to vaginal delivery in pregnant women undergoing induction of labor were Bishop score ⩾4 and higher parity ⩾1, regardless of the occurrence of gestational hypertension.
DISCLOSURES: N.V. Leal: None. A.S. Souza: None. L. Katz: None. C. Noronha-Neto: None. S.B. Maia: None. A.H. Franca-Neto: None. M.M. Amorim: None.
METHODS: We conducted a cohort study, with pregnant women submitted to induction of labor with misoprostol, evaluating normotensive and hypertensive gestation. All pregnancies had a live fetus. The main outcomes analyzed were: age, parity, number of pregnancies, gestational age, index of amniotic fluid, Bishop score, fetus weight estimated by ultrasound, premature rupture of membranes, diabetes, peridural analgesia, presence of meconium in the amniotic liquid, cervical modifications, time of induction, time of labor and time between induction and labor, need of oxytocin, route of misoprostol administration and size of cervix by ultrasound. For statistical analysis we used the chi-square test or Fisher's exact test, as appropriate, at a significance level of 5%. We also calculated the risk ratio (RR) and its confidence interval 95% (95% CI).
RESULTS: We evaluated 410 pregnant women submitted to induction of labor with misoprostol, 227 in normotensive and 183 in hypertensive gestation. The frequency of vaginal delivery was similar in both groups, with 61,2% in normotensive pregnant women and 57.4% in hypertensive (p=0.43). The risk factors associated with vaginal delivery in both women were, respectively: Bishop score ⩾4 (OR=1.87; 95%CI: 1.06-3.29; p=0.03) and (OR=2.31; 95%CI: 1.25-4.28; p=0.008) and parity ⩾1 (OR=4.36; 95%CI: 2.16-8.80; p<0.0001) and (OR=2.61; 95%CI: 1.36-5.04; p=0.004).
CONCLUSIONS: The main factors associated with progression to vaginal delivery in pregnant women undergoing induction of labor were Bishop score ⩾4 and higher parity ⩾1, regardless of the occurrence of gestational hypertension.
DISCLOSURES: N.V. Leal: None. A.S. Souza: None. L. Katz: None. C. Noronha-Neto: None. S.B. Maia: None. A.H. Franca-Neto: None. M.M. Amorim: None.
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