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Pregnancy Hypertension

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https://www.readbyqxmd.com/read/30213723/welcome-to-isom-2018
#1
Sandra Lowe
No abstract text is available yet for this article.
October 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30213722/welcome-message-from-the-organizing-committees-of-isom-mom-s-and-isshp
#2
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30213721/welcome-message-from-the-isshp-president
#3
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177080/effects-of-klotho-polymorphisms-on-preeclampsia-risk-in-a-case-control-study
#4
Jingli Wang, Yan Lin, Fuyan Lv, Huabin Hou, Kaiqiu Chu, Bing Jiang, Jingjing Liu, Shiguo Liu, Bo Hou
Preeclampsia (PE) is a serious disorder of human pregnancy and always is accompanied with multi-organ disorder, which severely threatens the health of both the mothers and the offspring. The oxidative stress and genetic factors involves in the development of PE. The Klotho encodes Klotho protein that is capable of increasing resistance to oxidative stress. Thus, we designed this case-control study to investigate the association between Klotho polymorphisms and the susceptibility to PE in Chinese Han women. Two single nucleotide polymorphisms (SNPs) (rs1207568 and rs564481) in Klotho were selected to be genotyped in 1002 PE patients and 1384 normal controls with TaqMan allelic discrimination real-time PCR technology...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177079/first-trimester-placental-vascularization-and-angiogenetic-factors-are-associated-with-adverse-pregnancy-outcome
#5
Johanna E W Leijnse, Roel de Heus, Wilco de Jager, Wendy Rodenburg, Louis L H Peeters, Arie Franx, Niels Eijkelkamp
BACKGROUND: Hypertensive disorders, fetal growth restriction and preterm birth are major obstetrical complications and are related to impaired placentation. Early identification of impaired placentation can advance clinical care by preventing or postpone adverse pregnancy outcome. OBJECTIVES: Determine whether sonographic assessed placental vascular development and concomitant changes in inflammation- and/or angiogenesis-related serumproteins differ in the first trimester between uncomplicated pregnancies and pregnancies with adverse outcome...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177078/urinary-congophilia-in-preeclampsia-experience-from-a-rural-tertiary-care-hospital-in-india
#6
Chandrakala Nagarajappa, Sheela Shikaripur Rangappa, Ravishankar Suryanarayana, Sharath Balakrishna
OBJECTIVES: To evaluate the presence of urinary congophilia amongIndian patients with preeclampsia. STUDY DESIGN: A prospective case control study in which congophilia of urine samples from preeclamptic pregnant women (n = 62) and normotensive pregnant women (n = 65) was compared by using Congo Red Dot Blot assay. MAIN OUTCOME MEASURES: Presence of urinary congophilia. RESULTS: Mean percentage of Congo Red Retention was 37...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177077/high-sensitivity-cardiac-troponin-i-levels-in-preeclampsia
#7
Adam Morton, Anthony Morton
Pre-eclampsia may be associated with cardiac complications including pulmonary oedema. Nine studies examining whether pre-eclampsia is associated with elevated levels of cardiac troponin (cTnI) revealed inconsistent results. In this study high sensitivity cardiac troponin I (hscTnI) levels were measured in 40 asymptomatic women with pre-eclampsia . HscTnI was elevated in ten (25%) women. A linear correlation between peak mean arterial pressure and log hscTnI was demonstrated.
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177076/24-hour-blood-pressure-variability-as-a-predictor-of-short-term-echocardiographic-changes-in-normotensive-women-with-past-history-of-preeclampsia-eclampsia
#8
Mohammad AbdelKader AbdelWahab, Hazem Mohammad-Ali Farrag, Cristina Eid Saied
OBJECTIVES: To investigate the association between 24-hr blood pressure variability (BPV) and subclinical echocardiographic changes and microalbuminuria in normotensive women with history of preeclampsia/eclampsia. BACKGROUND: Ambulatory blood pressure monitoring (ABPM) has been used as a valuable method in determining cardiovascular (CV) risk and target organ damage. Although hypertension and proteinuria that define preeclampsia/eclampsia may resolve in the majority of women, a significantly greater risk of CV and renal disease is present in their later life...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177075/serum-fatty-acids-are-positively-associated-with-changes-in-systemic-blood-pressure-throughout-pregnancy
#9
Jaqueline Lepsch, Dayana Rodrigues Farias, Ilana Eshriqui, Fernanda Rebelo, Juliana Dos Santos Vaz, Amanda Amorim Adegboye, Joseph R Hibbeln, Gilberto Kac
OBJECTIVES: To assess whether serum concentrations of saturated (SFAs), polyunsaturated (PUFAs), and monounsaturated (MUFAs) fatty acids are associated with changes in blood pressure (BP) throughout pregnancy. STUDY DESIGN: Prospective cohort. MAIN OUTCOME MEASURES: Longitudinal measurements of systolic (SBP) and diastolic (DBP) BP. METHODS: Two hundred twenty-three healthy pregnant women were recruited in a public health center in Rio de Janeiro, Brazil between 2009 and 2011...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177074/increased-rate-of-birth-defects-after-first-trimester-use-of-angiotensin-converting-enzyme-inhibitors-treatment-or-hypertension-related-an-observational-cohort-study
#10
Maria Hoeltzenbein, Tatjana Tissen-Diabaté, Anne-Katrin Fietz, Sandra Zinke, Angela Kayser, Reinhard Meister, Corinna Weber-Schoendorfer, Christof Schaefer
OBJECTIVES: To analyze the risk of spontaneous abortions and major birth defects in pregnancies of women treated with angiotensin converting enzyme inhibitors (ACEIs) during the first trimester. STUDY DESIGN: Observational cohort study of prospectively ascertained pregnancies from the German Embryotox pharmacovigilance institute. Pregnancy outcomes after maternal exposure to ACEIs during the first trimester were compared with pregnancies without antihypertensive treatment...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177073/creating-biobanks-in-low-and-middle-income-countries-to-improve-knowledge-the-prepare-initiative
#11
Leandro De Oliveira, Marcos Augusto Bastos Dias, Arundhanthi Jeyabalan, Beth Payne, Christopher W Redman, Laura Magee, Lucilla Poston, Lucy Chappell, Paul Seed, Peter von Dadelszen, James Michael Roberts
The Millennium Development Goal 5, a project signed in 2000, intended to improve maternal health and reduce maternal mortality by 75% by 2015. Despite all efforts, little progress has been achieved in low and middle-income countries (LMIC) and 99% of all maternal deaths related to pre-eclampsia (PE) still occur in these settings. It is important to determine whether women in LMIC, where PE carries a greater risk than in high-income countries (HIC), have unique risk factors. Some variances may alter the risk, severity and pertinent pathophysiology of PE...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177072/maternal-serum-b-cell-activating-factor-in-hypertensive-and-normotensive-pregnancies
#12
J Tay, A Costanzi, K Basello, G Piuri, E Ferrazzi, A F Speciani, C C Lees
OBJECTIVES: The objective of this study was the analysis of B-Cell Activating Factor (BAFF) levels in pregnancies affected by PE, and in pregnancies affected by fetal growth restriction without Hypertensive disorders and its possible correlation with pulse wave velocity and cardiac output. STUDY DESIGN: Prospective study of 69 women at 24-40 weeks gestation. Haemodynamic function was assessed in those with Pre-eclampsia (PE, n = 19), fetal growth restriction (FGR, n = 10) and healthy pregnancies (n = 40)...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177071/the-effect-of-low-dose-aspirin-on-serum-placental-growth-factor-levels-in-a-high-risk-predo-cohort
#13
K Murtoniemi, T Vahlberg, E Hämäläinen, E Kajantie, A K Pesonen, K Räikkönen, P Taipale, P M Villa, H Laivuori
OBJECTIVES: Our first aim was to study the longitudinal changes of serum placental growth factor (PlGF) concentration between 12+0 and 28+0 weeks of gestation in the prospective PREDO cohort. Our second aim was to study the effect of low-dose acetylsalicylic acid (LDA; 100 mg/day), started before the 14th week of gestation, on PlGF concentration. STUDY DESIGN: Blood samples were collected at 12+0 -14+0 , 18+0 -20+0 and 26+0 -28+0 weeks of gestation in 101 women without and 309 with clinical risk factors for pre-eclampsia...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177070/mri-derived-aortic-characteristics-after-pregnancy-the-ambityon-study
#14
G A Gerbrand Zoet, A K Anna Sverrisdóttir, A L M Anouk Eikendal, A Arie Franx, T Tim Leiner, B B Bas van Rijn
OBJECTIVES: Pregnancy and pregnancy complications have been associated with increased arterial stiffness even at young age. In this study we assessed the impact of parity on CMR-derived aortic characteristics as early markers of atherosclerosis and arterial stiffness in healthy women between 25 and 35 years. STUDY DESIGN: We studied 68 women who participated in the AMBITYON study, a prospective population-based cohort study for assessment of atherosclerotic burden by MRI and traditional CVD risk factors in healthy, young adults...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177069/dysfunction-of-pseudogene-pgk1p2-is-involved-in-preeclampsia-by-acting-as-a-competing-endogenous-rna-of-pgk1
#15
Jing Tong, Jieqiong Yang, Hong Lv, Shijian Lv, Cong Zhang, Zi-Jiang Chen
OBJECTIVES: Normal decidualization is essential for normal pregnancy and abnormal decidualization is thought to cause preeclampsia (PE). Phosphoglycerate kinase 1 (PGK1) is an enzyme involved in the glycolytic pathway which is the main metabolism process decidual cells exhibit. Phosphoglycerate kinase 1, pseudogene 2 (PGK1P2), which is also a long non-coding RNA (lncRNA), has a high sequence similarity to PGK1 and therefore acquires an ability for sequence-specific regulation. METHODOLOGY: The expression of PGK1 and PGK1P2 in human decidua, as well as their relationship and functions during decidualization was investigated using in vitro cultured human endometrial stromal cell lines (hESCs) and primary ESCs by real-time PCR, immunohistochemistry, western blotting, siRNA techniques and miRNA inhibitor or mimic transfection...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177068/economic-evaluation-of-sflt-1-plgf-ratio-test-in-pre-eclampsia-prediction-and-diagnosis-in-two-brazilian-hospitals
#16
Sarah Franco Figueira, Cyrill Wolf, Marisa D'Innocenzo, João Paulo Venezian de Carvalho, Mariana Granado Barbosa, Eduardo Zlotnik, Eduardo Cordioli
OBJECTIVES: To assess the economic impact of introducing the soluble FMS-like tyrosine kinase (sFlt-1) to placental growth factor (PlGF) ratio test into clinical practice in two Brazilian hospitals. METHODS: An economic model estimating the incremental value of the information from a Brazilian public and private healthcare payer perspective generated by the sFlt-1/PlGF ratio test, compared with current diagnostic procedures, in guiding the management of women with suspected pre-eclampsia...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177067/keeping-eyes-on-preeclampsia
#17
Lucie Sedille, Fabrice Pierre, Olivier Pourrat, David Desseauve
No abstract text is available yet for this article.
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177066/clinical-implementation-of-the-sflt-1-plgf-ratio-to-identify-preeclampsia-and-fetal-growth-restriction-a-prospective-cohort-study
#18
I Herraiz, E Simón, P I Gómez-Arriaga, M S Quezada, A García-Burguillo, E A López-Jiménez, A Galindo
OBJECTIVE: To analyze the usefulness of a clinical protocol for early detection of preeclampsia and/or fetal growth restriction (PE/FGR) using, in previously selected pregnancies, the measurement of the sFlt-1/PlGF ratio at 24-28 weeks of gestation. STUDY DESIGN: Prospective observational cohort study carried out in a single tertiary hospital in Spain. 5601 consecutive singleton pregnancies with complete follow-up were included. High-risk women for PE/FGR were selected by combining data from maternal history and second trimester uterine artery Doppler...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177065/peripartum-cardiomyopathy-an-epidemiologic-study-of-early-and-late-presentations
#19
Reza Masoomi, Zubair Shah, Zoltan Arany, Kamal Gupta
OBJECTIVE: Peripartum cardiomyopathy (PPCM) can present during pregnancy and up to months post-delivery. Most large-scale epidemiologic studies have reported on cases occurring during pregnancy or the first few days postpartum (termPPCM). Limited information is available on PPCM in the later postpartum period (latePPCM). We studied the incidence, predictors, and hospital outcome of peripartum cardiomyopathy (PPCM) in the prepartum and immediate post delivery period versus up to 3 months post-delivery...
July 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/30177064/gestational-diabetes-modifies-the-association-between-plgf-in-early-pregnancy-and-preeclampsia-in-women-with-obesity
#20
Matias C Vieira, Shahina Begum, Paul T Seed, Dania Badran, Annette L Briley, Carolyn Gill, Keith M Godfrey, Deborah A Lawlor, Scott M Nelson, Nashita Patel, Naveed Sattar, Sara L White, Lucilla Poston, Dharmintra Pasupathy
OBJECTIVE: To identify clinical and biomarker risk factors for preeclampsia in women with obesity and to explore interactions with gestational diabetes, a condition associated with preeclampsia. STUDY DESIGN: In women with obesity (body mass index ≥ 30 kg/m2 ) from the UK Pregnancies Better Eating and Activity Trial (UPBEAT), we examined 8 clinical factors (socio-demographic characteristics, BMI, waist circumference and clinical variables) and 7 biomarkers (HDL cholesterol, hemoglobin A1c, adiponectin, interleukin-6, high sensitivity C-reactive protein, and placental growth factor (PlGF)) in the early second trimester for association with later development of preeclampsia using logistic regression...
July 2018: Pregnancy Hypertension
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