Structural plasticity allows UCH37 to be primed by RPN13 or locked down by INO80G.

Xiang Chen, Kylie J Walters

Molecular Cell 2015 March 6

Two studies in this issue of Molecular Cell,VanderLinden et al. (2015) and Sahtoe et al. (2015),report crystal structures that define how deubiquitinating enzyme UCH37 is switched on or off by proteasome ubiquitin receptor RPN13 or chromatin remodeler component INO80G.

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