Role of chemoreceptors in the zone of vertebral arteries in the formation of the cardiorespiratory functional system.

Chemoreceptors in reflexogenic zones of the vertebral and carotid arteries play a regulatory role in the cardiorespiratory interaction. Perfusion of these zones with lactic acid solution (0.5-3.0 mmol/liter) produced a reflex response, which was manifested in stimulation of external respiration and increase in systemic blood pressure. The reflex response of these systems was opposite after local administration of 0.3 M Tris-buffer. Correlation analysis revealed the role of afferentation from reflexogenic zones in the formation of a regulatory functional system for tissue gas exchange and acid-base balance.