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Journal Article
Research Support, Non-U.S. Gov't
Gene expression profile of abdominal aortic aneurysm rupture.
Annals of the New York Academy of Sciences 2006 November
To search for novel transcriptional pathways that are activated in abdominal aortic aneurysm rupture, cDNA microarrays were used to compare global mRNA expression at the aneurysm rupture edge to anterior sac, and selected results were confirmed using quantitative real-time-polymerase chain reaction (QRT-PCR). This study identified apoptosis, angiogenesis, and inflammation as potentially important participants during the process of aneurysm rupture.
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