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Sharaf-Eldin Shehada, Yacine Elhmidi, Öznur Öztürk, Markus Kasel, Antonio H Frangieh, Fanar Mourad, Jaroslav Benedik, Jaafar El Bahi, Mohamed El Gabry, Matthias Thielmann, Heinz Jakob, Daniel Wendt
Aim: Aortic valve replacement (AVR) in patients with prior cardiac surgery might be challenging. Transcatheter aortic valve replacement (TAVR) offers a promising alternative in such patients. We therefore aimed at comparing the outcomes of patients with aortic valve diseases undergoing TAVR versus those undergoing surgical AVR (SAVR) after previous cardiac surgery. Methods and Results: MEDLINE, EMBASE, and the Cochrane Central Register were searched. Seven relevant studies were identified, published between 01/2011 and 12/2015, enrolling a total of 1148 patients with prior cardiac surgery (97...
2018: Cardiology Research and Practice
Bilal Ahmad Paray, Irfan A Rather, Mohammad K Al-Sadoon, Al-Shammari Fanar Hamad
Aquatic animals are known for their myriad of beneficial bacteria with diverse biologically active compounds. The current study was aimed to isolate and characterize potentially beneficial lactic acid bacteria from Nile Tilapia and evaluate their pharmaceutical applications. The fish samples were dissected and stomach, intestine, and gills were collected and serially diluted for the isolation of lactic acid bacteria (LAB) on BCP agar media. Identification of isolate was carried by biochemical and molecular characterization using API kit and 16S rRNA gene sequencing analysis, respectively...
May 2018: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
Mohamed El-Gabry, Sharaf-Eldin Shehada, Daniel Wendt, Fanar Mourad
Occlusion of the left atrial appendage (LAA) in patients with atrial fibrillation has become a standard therapy to prevent thromboembolic complications. We aim to present 3 cases of LAA occluder embolization after percutaneous WATCHMAN™ device implantation, which required emergent surgical retrieval. The device was dislocated in the left atrium, introducing LAA perforation and resulting in pericardial effusion and later tamponade in 1 patient who developed multiorgan failure and died 8 days postoperatively...
January 29, 2018: European Journal of Cardio-thoracic Surgery
Alshammari Fanar Hamad, Jong-Hun Han, Byung-Chun Kim, Irfan A Rather
The past decade has proven the competence of nanotechnology in almost all known fields. The evolution of nanotechnology today in the area of the food industry has been largely and has had a lot of contribution in the food processing, food package, and food preservation. The increasing global human population has come with growing population to be fed, and food production is not adjusted to at par with the growing population. This mismatch has shown the real essence of food preservation so that food products can reach to people on a global scale...
January 2018: Saudi Journal of Biological Sciences
Jaroslav Benedik, Sharaf-Eldin Shehada, Fanar Mourad, Yacine Elhmidi, Juri Lubarski, Konstantinos Tsagakis, Heinz Jakob, Martin Kostelka
No abstract text is available yet for this article.
January 9, 2018: Journal of Cardiovascular Surgery
Rajaa M Al-Raddadi, Noha A Dashash, Hani A Alghamdi, Zeyad M Al-Raddadi, Hanan S Alzahrani, Abdullah J Alsahafi, Abdullah M Algarni, Majed M Alghamdi, Raghad F Hakim, Abdulmohsen H Al-Zalabani, Fanar Hakim, Feras A Moria
The infection rate of the hepatitis C virus (HCV) in Saudi Arabia is among the lowest in the world. However, it is likely that poor knowledge and awareness of HCV infection could minimize the effectiveness of prevention and control programs in the kingdom. Thus, the study objective was to estimate the prevalence of HCV infection, and to assess current knowledge about it, in the targeted population. Data on 5482 Saudi people attending primary healthcare centers in Jeddah City in 2014/2015 were analyzed in this cross-sectional study...
March 2018: Journal of Medical Virology
Sharaf-Eldin Shehada, Yacine Elhmidi, Fanar Mourad, Daniel Wendt, Mohamed El Gabry, Jaroslav Benedik, Matthias Thielmann, Heinz Jakob
Conventional aortic valve replacement (CAVR) via a full sternotomy is the standard surgical approach for aortic valve replacement. Minimal access aortic valve replacement (MAAVR) is commonly performed via a partial sternotomy and a right minithoracotomy. Such procedures aim not only to reduce the invasiveness but to offer the same quality, safety and results of the conventional approach. Our goal was to compare both procedures by performing a meta-analysis of reports with risk adjustment that performed a propensity-matched analysis...
October 1, 2017: Interactive Cardiovascular and Thoracic Surgery
Irfan Ahmad Rather, Rajib Majumder, Fanar Hamad Alshammari, Jae Gyu Park, Vivek Kumar Bajpai
Ulcerative colitis is an inflammatory disease of the large intestine whose effects are bloody diarrhea, cramping and bloating. The disease is usually relapsing and remitting. However, the cause of ulcerative colitis is not yet known. Due to this reason, finding an effective treatment has been a great challenge. The suggested medical treatment is usually composed of two portions; keeping the flare up from happening and treating the flare up when it has happened. Active flare ups are treated with corticosteroids...
September 2016: Pakistan Journal of Pharmaceutical Sciences
Lisa Himpel, Kevin Pilarczyk, Aziz Wahbi, Fanar Mourad, Konstantinos Tsagakis, Heinz Jakob, Jaroslav Benedik
OBJECTIVES: The mechanisms of the location and extension of acute aortic dissection (AD) are only poorly understood. The aim of this study was to compare the cohesion of the non-coronary aortic sinus (NAS) and the ascending aortic wall (AA) using the Dissectometer - a new device for analyses of the mechanical properties of the aorta. DESIGN: The properties of the aortic wall were analyzed with the "Dissectometer" (parameters P7, P8 and P9) in adult patients undergoing aortic root (AR) replacement in two different segments: NAS and AA...
February 2017: Scandinavian Cardiovascular Journal: SCJ
Salma K Ahmed, Naeema Mahmood, Zainab H Malalla, Fanar M Alsobyani, Israa S Al-Kiyumi, Wassim Y Almawi
The aim of this study is to investigate the association of recurrent pregnancy loss (RPL) with altered C-reactive protein (CRP) serum levels, and genetic variation in CRP gene. This was a retrospective case-control study, involving 275 women with three or more consecutive pregnancy losses, and 290 age-matched control women, who were recruited from outpatient obstetrics/gynecology clinics. CRP serum levels (hs-CRP) were determined by latex-enhanced nephelometry, and CRP genotyping was done by allelic discrimination...
September 10, 2015: Gene
Jaroslav Benedik, Fanar Mourad, Mareike Eißmann, Heinz Jakob
No abstract text is available yet for this article.
March 2015: Annals of Cardiothoracic Surgery
M Dashprakash, Gnanavel Venkatesan, Muthannan Andavar Ramakrishnan, Dhanavelu Muthuchelvan, Muthu Sankar, Awadh Bihari Pandey, Bimelendu Mondal
The fusion gene (ORF 117) sequences of twelve (n = 12) capripox virus isolates namely sheeppox (SPPV) and goatpox (GTPV) viruses from India were demonstrated for their genetic and phylogenetic relationship among them. All the isolates were confirmed for their identity by routine PCR before targeting ORF 117 gene for sequence analysis. The designed primers specifically amplified ORF 117 gene as 447 bp fragment from total genomic DNA extracted from all the isolates. Sequence analysis revealed a significant percentage of identity among GTPV, SPPV and between them at both nucleotide and amino acid levels...
April 2015: Virus Genes
Jaroslav Benedik, Daniel S Dohle, Daniel Wendt, Kevin Pilarczyk, Vivien Price, Fanar Mourad, Elizaveta Zykina, Ferdinand Stebner, Konstantinos Tsagakis, Heinz Jakob
OBJECTIVES: A bicuspid aortic valve (BAV) is commonly associated with aortic wall abnormalities, including dilatation of the ascending aorta and increased potential for aortic dissection. We compared the mechanical properties of the aortic wall of BAV patients with aortic valve stenosis (AS) and regurgitation (AR) using a dissectometer, a device mimicking transverse aortic wall shear stress. METHODS: Between March 2010 and February 2013, 85 consecutive patients with bicuspid aortic valve undergoing open aortic valve replacement at our institution were prospectively enrolled, presenting either with stenosis (Group 1, n = 58) or regurgitation (Group 2, n = 27)...
December 2014: European Journal of Cardio-thoracic Surgery
R Yogisharadhya, V Bhanuprakash, M Hosamani, G Venkatesan, V Balamurugan, D P Bora, V Bhanot, M Prabhu, R K Singh
In the present study, two sheeppox vaccines made from strains [sheeppox virus-Srinagar (SPPV-Srin) and Ranipet (SPPV-R)] indigenous to India and adapted to Vero cells were compared in terms of their safety, potency, efficacy and antigenic value with the commercial in-use Roumanian Fanar (SPPV-RF) vaccine, a foreign strain adapted in primary lamb testes cells. The safety test indicated that the SPPV (Sri and RF) vaccines were safe while SPPV-R was not completely attenuated and caused excessive adverse reactions at the passage level tested...
November 2011: Biologicals: Journal of the International Association of Biological Standardization
S S Chaudhary, K D Pandey, R P Singh, P C Verma, P K Gupta
The combined sheep pox and Peste des Petits ruminants (PPR) vaccine was prepared in lyophilized form containing recommended doses of both vaccine viruses. Safety and immunogenicity of this combined vaccine was evaluated in sheep. Sheep immunized subcutaneously with 1ml of live attenuated vaccine consisting of 10(3)TCID(50) each of sheep pox virus (SPV) Romanian Fanar (RF) strain and Peste des Petits ruminants virus (PPRV-Sungri/96 strain) were monitored for clinical and serological responses for a period of four weeks post immunization (pi) and two week post challenge (pc)...
April 28, 2009: Vaccine
R Khoury, A Geahchan, C M Coste, M A Antoun, N S Kawar
The retention and fate of triadimefon fungicide were studied under two environmental conditions. Field studies were conducted on two soils, a sandy loam soil (Fanar) and a clay soil (Raouda). Fanar is a wet coastal area while Raouda is a dry agricultural area of the Bekaa plain located at an elevation of 870 m above sea level. Triadimefon was applied with a jet sprayer at 267 g a.i.ha(-1) and 200 g a.i.ha(-1) at Fanar and Raouda, respectively. Reconstituted soil columns (600 x 30 mm) glasses, were used to study the fungicide movement and metabolism in the two soils...
November 2001: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
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