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https://www.readbyqxmd.com/read/29141447/what-is-offered-on-mobile-applications-in-spanish-about-diabetes-mellitus
#1
Paul Jesús Tejada-Llacsa, Stalin Yance-Contreras, Leidy Machuca-Felipa, Carlos A Cordova-Cassia
No abstract text is available yet for this article.
November 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29136819/alteration-in-the-liver-metabolome-of-rats-with-metabolic-syndrome-after-treatment-with-hydroxytyrosol-a-mass-spectrometry-and-nuclear-magnetic-resonance-based-metabolomics-study
#2
Ioanna Dagla, Dimitra Benaki, Eirini Baira, Nikolaos Lemonakis, Hemant Poudyal, Lindsay Brown, Anthony Tsarbopoulos, Alexios-Leandros Skaltsounis, Emmanouel Mikros, Evagelos Gikas
Metabolic syndrome (MetS) represents a group of abnormalities that enhances the risk for cardiovascular disease, diabetes and stroke. The Mediterranean diet seems to be an important dietary pattern, which reduces the incidence of MetS. Hydroxytyrosol (HT) - a simple phenol found in olive oil - has received increased attention for its antioxidant activity. Recently, the European Foods Safety Authority (EFSA) claimed that dietary consumption of HT exhibits a protective role against cardiovascular disease. In this study, an experimental protocol has been setup, including isolated HT administration in a diet induced model of MetS in young Wistar rats, in order to find out whether HT has a protective effect against MetS...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29132746/diabetes-mellitus-as-a-poor-mobilizer-condition
#3
REVIEW
Gian Paolo Fadini, John F DiPersio
Hematopoietic stem cell (HSC) transplantation in an effective and curative therapy for numerous hematological malignancies. Mobilization of HSCs from bone marrow (BM) to peripheral blood (PB) followed by apheresis is the gold standard for obtaining HSCs for both autologous and allogeneic stem cell transplantation. After administration of granulocyte-colony stimulating factor (G-CSF), up to 30% of patients fail to mobilize "optimal" numbers of HSCs required for engraftment. This review summarizes the current experimental and clinical evidence that diabetes mellitus is a risk factor for poor mobilization...
November 8, 2017: Blood Reviews
https://www.readbyqxmd.com/read/29129715/reducing-barriers-to-healthy-weight-planned-and-responsive-adaptations-to-a-lifestyle-intervention-to-serve-people-with-impaired-mobility
#4
Andrea C Betts, Katherine Froehlich-Grobe, Simon Driver, Danielle Carlton, M Kaye Kramer
BACKGROUND: People with impaired mobility (IM) disabilities have a higher prevalence of obesity and obesity-related chronic conditions; however, lifestyle interventions that address the unique needs of people with IM are lacking. OBJECTIVE: This paper describes an adapted evidence-based lifestyle intervention developed through community-based participatory research (CBPR). METHODS: Individuals with IM, health professionals, disability group representatives, and researchers formed an advisory board to guide the process of thoroughly adapting the Diabetes Prevention Program Group Lifestyle Balance (DPP GLB) intervention after a successful pilot in people with IM...
October 27, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29117077/vascular-graft-infection-incidence-and-potential-risk-factors
#5
Catherine R Ratliff, David Strider, Tanya Flohr, Danielle Moses, Virginia Rovnyak, Julie Armatas, Jennifer Johnson, Alison Okerlund, Mary Baldwin, Marian Lawson, Suzanne Fuhrmeister, Margaret C Tracci, Gilbert R Upchurch, Kenneth J Cherry
PURPOSE: The purpose of this study was to identify factors that increase the risk of vascular graft infections (VGI) in patients following abdominal or lower extremity revascularization surgery. DESIGN: Retrospective, descriptive study. METHODS: We reviewed the electronic health records of 223 patients who had undergone abdominal or lower extremity revascularization procedures from July 2012 to November 2014, looking for factors associated with VGI...
November 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/29109612/pilot-study-for-managing-complex-chronic-care-medicaid-patients-with-diabetes-using-a-mobile-health-application-achieves-triple-aim-improvement-in-a-primary-care-setting
#6
Marit L Bovbjerg, Jenney Lee, Rosa Wolff, Bobby Bangs, Michael A May
IN BRIEF Cost-effective innovations to improve health and health care in patients with complex chronic diseases are urgently needed. Mobile health (mHealth) remote monitoring applications (apps) are a promising technology to meet this need. This article reports on a study evaluating patients' use of a tablet device with an mHealth app and a cellular-enabled glucose meter that automatically uploaded blood glucose values to the app. Improvements were observed across all three components of the Patient Protection and Affordable Care Act's "triple aim...
October 2017: Clinical Diabetes: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29108997/chlamydia-pneumoniae-exploits-adipocyte-lipid-chaperone-fabp4-to-facilitate-fat-mobilization-and-intracellular-growth-in-murine-adipocytes
#7
Nirwana Fitriani Walenna, Yusuke Kurihara, Bin Chou, Kazunari Ishii, Toshinori Soejima, Ryota Itoh, Akinori Shimizu, Takeshi Ichinohe, Kenji Hiromatsu
Fatty acid-binding protein 4 (FABP4), a cytosolic lipid chaperone predominantly expressed in adipocytes and macrophages, modulates lipid fluxes, trafficking, signaling, and metabolism. Recent studies have demonstrated that FABP4 regulates metabolic and inflammatory pathways, and in mouse models its inhibition can improve type 2 diabetes mellitus and atherosclerosis. However, the role of FABP4 in bacterial infection, metabolic crosstalk between host and pathogen, and bacterial pathogenesis have not been studied...
November 3, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29108826/physical-activity-and-autoimmune-diseases-get-moving-and-manage-the-disease
#8
REVIEW
Kassem Sharif, Abdulla Watad, Nicola Luigi Bragazzi, Micheal Lichtbroun, Howard Amital, Yehuda Shoenfeld
Physical activity, by definition, is any skeletal muscle body movement that results in energy expenditure. In the last few decades, a plethora of scientific evidences have accumulated and confirmed the beneficial role of physical activity as a modifiable risk factor for a wide variety of chronic diseases including cardiovascular diseases (CVDs), diabetes mellitus and cancer, among others. Autoimmune diseases are a heterogeneous group of chronic diseases, which occur secondary to loss of self-antigen tolerance...
November 3, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29108571/wearable-non-invasive-epidermal-glucose-sensors-a-review
#9
Jayoung Kim, Alan S Campbell, Joseph Wang
The growing recent interest in wearable and mobile technologies has led to increased research efforts toward development of non-invasive glucose monitoring platforms. Continuous glucose monitoring addresses the limitations of finger-stick blood testing and provides the opportunity for optimal therapeutic interventions. This article reviews recent advances and challenges toward the development of non-invasive epidermal electrochemical glucose sensing systems. Recent reports claim success in glucose monitoring in human subjects using skin-worn electrochemical sensors...
January 15, 2018: Talanta
https://www.readbyqxmd.com/read/29107565/rubber-stamp-templates-for-improving-clinical-documentation-a-paper-based-m-health-approach-for-quality-improvement-in-low-resource-settings
#10
Bernadette Kleczka, Anita Musiega, Grace Rabut, Phoebe Wekesa, Paul Mwaniki, Michael Marx, Pratap Kumar
BACKGROUND: The United Nations' Sustainable Development Goal #3.8 targets 'access to quality essential healthcare services'. Clinical practice guidelines are an important tool for ensuring quality of clinical care, but many challenges prevent their use in low-resource settings. Monitoring the use of guidelines relies on cumbersome clinical audits of paper records, and electronic systems face financial and other limitations. Here we describe a unique approach to generating digital data from paper using guideline-based templates, rubber stamps and mobile phones...
October 23, 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29101051/histone-methyltransferase-g9a-modulates-hepatic-insulin-signaling-via-regulating-hmga1
#11
Weili Xue, Jin Huang, Hong Chen, Yu Zhang, Xiuqin Zhu, Jianshuang Li, Wenquan Zhang, Yangmian Yuan, Yan Wang, Ling Zheng, Kun Huang
Hepatic insulin sensitivity is critical for glucose homeostasis, and insulin resistance is a fundamental syndrome found in various metabolic disorders, including obesity and type 2 diabetes. Despite considerable studies on the mechanisms of hepatic insulin resistance, the link between epigenetic regulation and the development of insulin resistance remains elusive. Here, we reported that G9a/EHMT2, a histone methyltransferase, was markedly decreased in the liver of db/db mice and high-fat diet (HFD)-fed mice...
October 31, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29094298/optimizing-glycemic-control-through-titration-of-insulin-glargine-100-u-ml-a-review-of-current-and-future-approaches-with-a-focus-on-asian-populations
#12
REVIEW
Chaicharn Deerochanawong, Shailendra Bajpai, I Made Pande Dwipayana, Zanariah Hussein, Maria Aileen Mabunay, Reynaldo Rosales, Shih-Tzer Tsai, Man Wo Tsang
Various data have demonstrated inadequate glycemic control amongst Asians with type 2 diabetes mellitus (T2DM), possibly on account of suboptimal titration of basal insulin-an issue which needs to be further examined. Here we review the available global and Asia-specific data on titration of basal insulin, with a focus on the use of insulin glargine 100 U/mL (Gla-100). We also discuss clinical evidence on the efficacy and safety of titrating Gla-100, different approaches to titration, including some of the latest technological advancements, and guidance on the titration of basal insulin from international and local Asian guidelines...
December 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29091741/skeletal-muscle-and-fetal-alcohol-spectrum-disorder
#13
Semone B Myrie, Mark A Pinder
Skeletal muscle is critical for mobility and many metabolic functions integral to survival and long-term health. Alcohol can affect skeletal muscle physiology and metabolism, which will have immediate and long-term consequences on health. While skeletal muscle abnormalities, including morphological, biochemical and functional impairments are well documented in adults consuming excessive alcohol, there is a scarcity of information about skeletal muscle in the prenatal alcohol exposure (PAE) offspring. This review examines the available studies addressing skeletal muscle abnormalities due to PAE...
November 1, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/29079451/2-ome-lysophosphatidylcholine-analogues-are-gpr119-ligands-and-activate-insulin-secretion-from-%C3%AE-tc-3-pancreatic-cells-evaluation-of-structure-dependent-biological-activity
#14
Anna Drzazga, Agata Sowińska, Agnieszka Krzemińska, Andrzej Okruszek, Piotr Paneth, Maria Koziołkiewicz, Edyta Gendaszewska-Darmach
GPR119 receptor has been proposed as a metabolic regulator playing a pivotal role in the modulation of glucose homeostasis in type 2 diabetes. GPR119 was identified on pancreatic β cells and its ligands have the ability to enhance glucose-stimulated insulin secretion (GSIS). Lysophosphatidylcholine (LPC) was shown to potentiate GSIS and our present studies indicate that 2-methoxy-lysophosphatidylcholine (2-OMe-LPC) analogues, unable to undergo 1→2 acyl migration, stimulate GSIS from murine βTC-3 pancreatic cells even more efficiently...
October 24, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29078781/physical-chronic-conditions-multimorbidity-and-sedentary-behavior-amongst-middle-aged-and-older-adults-in-six-low-and-middle-income-countries
#15
Davy Vancampfort, Brendon Stubbs, Ai Koyanagi
BACKGROUND: Sedentary behavior (SB) is, irrespective of a person's physical activity levels, associated with a wide range of deleterious outcomes such as diabetes, stroke and associated premature mortality. There are no nationally representative, multi-national, population-based studies investigating the relationship between SB, chronic conditions, and physical multimorbidity (i.e., two or more chronic physical conditions). Thus, this cross-sectional study aimed to assess the association between chronic conditions, physical multimorbidity and SB among community-dwelling adults in six low- and middle-income countries (LMICs)...
October 27, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29072012/-effect-of-electroacupuncture-intervention-on-gastrointestinal-motility-and-expression-of-insulin-like-growth-factor-1-and-its-receptor-proteins-in-gastric-antrum-in-diabetic-gastroparesis-rats
#16
Jian-Wen Yang, Yan Peng, Hai-Jiao Chen, Cheng-Cheng Zhang, Wei-Wei Liu, Li Liu, Mi Liu, Ya-Ping Lin
OBJECTIVE: To observe the effect of electroacupuncture (EA) intervention of "Zusanli"(ST 36), etc. on gastrointestinal motility and levels of insulin-like growth factor 1 (IGF-1) and IGF-1 receptor (IGF-1 R) proteins in the gastric antrum in diabetic gastroparesis (DGP) rats, so as to study its mechanism underlying improvement of DGP. METHODS: Fifty SD rats, half male and half female, were randomly allocated to control, model, EA acupoint, EA non-acupoint and medication (metoclopramide) groups (n=10 rats/group)...
August 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29071228/assay-of-desmopressin-acetate-in-nasal-spray-development-of-validated-pre-column-hplc-fluorescence-method
#17
Neeraj Upmanyu, Pawan Kumar Porwal
Purpose: Desmopressin acetate (DDAPV), a synthetic analogue of vasopressin, has been recommended to be used in diabetes insipidus, mild forms of hemophilia and Von Willebrand disease. The DDAPV is available for adminstration via different routes viz. oral, parenteral and nasal, however its dose is very less in case of nasal sprays (20 µg) and parenteral route (4 µg) compared to oral route (0.1 to 0.3 mg in tablet). A sensitive and selective method is needed to be developed and validated for assay of low concentrations of DDAPV in its pharmaceutical dosage form i...
September 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29067651/interventions-to-improve-management-of-chronic-conditions-among-racial-and-ethnic-minorities
#18
Riddhi Doshi, Robert H Aseltine, Alyse B Sabina, Garth N Graham
Digital and mhealth interventions can be effective in improving health outcomes among minority patients with diabetes, congestive heart failure, and chronic respiratory diseases. A number of electronic and digital approaches to individual and population-level interventions involving telephones, internet and web-based resources, and mobile platforms have been deployed to improve chronic disease outcomes. This paper summarizes the evidence supporting the efficacy of various behavioral and digital interventions targeting intermediate outcomes and hospitalizations with particular emphasis on studies examining the effects of these interventions on racial and ethnic minority population...
October 24, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29067622/factors-mediating-outcome-after-stroke-gender-thrombolysis-and-their-interaction
#19
Seung-Jae Lee, Sung Hyuk Heo, Walter T Ambrosius, Cheryl D Bushnell
Several studies, but not all, have shown that women benefit more from intravenous thrombolysis than men; few have accounted for pre-stroke mobility. Our aim was to determine whether there was an interaction between gender and thrombolysis treatment in 3-month modified Rankin Scale (mRS) score, after adjusting for pre-stroke mobility. We retrospectively reviewed medical records of 1390 consecutive ischemic stroke patients admitted between October 2012 and July 2015. The 3-month mRS was obtained from clinic visits...
October 24, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/29067269/the-influence-of-diabetes-distress-on-digital-interventions-for-diabetes-management-in-vulnerable-people-with-type-2-diabetes-a-qualitative-study-of-patient-perspectives
#20
Anne Sophie Mathiesen, Thordis Thomsen, Tonny Jensen, Charlotte Schiøtz, Henning Langberg, Ingrid Egerod
BACKGROUND: Digital interventions for improving diabetes management in Type 2 diabetes mellitus (T2DM) are used universally. Digital interventions are defined as any intervention accessed and taking input from people with T2DM in the form of a web-based or mobile phone-based app to improve diabetes self-management. However, the current confidence in digital interventions threatens to augment social inequalities in health, also known as the "digital divide". To counteract dissemination of the digital divide, we aimed to assess the potential of a tailored digital intervention for improving diabetes management in vulnerable people with T2DM...
September 2017: Journal of Clinical & Translational Endocrinology
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