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Benjamin C Riordan, Saleh Moradi, Kate B Carey, Tamlin S Conner, Kyungho Jang, Kelly E Reid, Damian Scarf
BACKGROUND: Alcohol use among university students is common, and those who drink often choose to drink heavily (ie, 4 or more drinks per session for women or 5 or more for men). Web-based interventions (WBIs), in which students complete assessments and receive personalized feedback about their alcohol use, and ecological momentary interventions (EMIs), which use mobile devices as a method of delivering intervention information, are 2 methods that have had some success in reducing alcohol use among university students...
May 15, 2018: JMIR Research Protocols
Eric Swanton, Lyndon Mason, Andy Molloy
The scarf osteotomy has become the workhorse procedure for a large proportion of foot and ankle surgeons, especially in Europe, in the treatment of hallux valgus. Such a versatile procedure should not be underestimated, and planning and thought should precede any such procedure. The angle of bone cuts and magnitude of translation dictate the final position, and all movement axes should be given equal attention.
June 2018: Foot and Ankle Clinics
P Chiwara, B O Ogutu, J Dash, E J Milton, J Ardö, M Saunders, G Nicolini
The amount of carbon uptake by vegetation is an important component to understand the functioning of ecosystem processes and their response/feedback to climate. Recently, a new diagnostic model called the Southampton Carbon Flux (SCARF) Model driven by remote sensing data was developed to predict terrestrial gross primary productivity (GPP) and successfully applied in temperate regions. The model is based on the concept of quantum yield of plants and improves on the previous diagnostic models by (i) using the fraction of photosynthetic active radiation absorbed by the photosynthetic pigment (FAPARps ) and (ii) using direct quantum yield by classifying the vegetation into C3 or C4 classes...
July 15, 2018: Science of the Total Environment
Vanessa L Scarf, Chris Rossiter, Saraswathi Vedam, Hannah G Dahlen, David Ellwood, Della Forster, Maralyn J Foureur, Helen McLachlan, Jeremy Oats, David Sibbritt, Charlene Thornton, Caroline S E Homer
BACKGROUND: The comparative safety of different birth settings is widely debated. Comparing research across high-income countries is complex, given differences in maternity service provision, data discrepancies, and varying research techniques and quality. Studies of births planned at home or in birth centres have reported both better and poorer outcomes than planned hospital births. Previous systematic reviews have focused on outcomes from either birth centres or home births, with inconsistent attention to quality appraisal...
April 3, 2018: Midwifery
Venkatesh Pilla Reddy, Khanh Bui, Graeme Scarfe, Diansong Zhou, Maria Learoyd
We report physiologically based pharmacokinetic-modeling analyses to determine olaparib (tablet or capsule) drug-drug interactions (DDIs). Verified DDI simulations provided dose recommendations for olaparib co-administration with clinically relevant CYP3A4 modulators to eliminate potential risk to patient safety or olaparib efficacy. When olaparib is given with strong/moderate CYP3A inhibitors, the dose should be reduced to 100/150 mg bid (tablet), and 150/200 mg bid (capsule). Olaparib administration is not recommended with strong/moderate CYP3A inducers...
May 1, 2018: Clinical Pharmacology and Therapeutics
Junichi Kushioka, Makoto Hirao, Hideki Tsuboi, Kosuke Ebina, Takaaki Noguchi, Akihide Nampei, Shigeyoshi Tsuji, Shosuke Akita, Jun Hashimoto, Hideki Yoshikawa
BACKGROUND: Arthrodesis of the first metatarsophalangeal (MTP) joint has been recommended for severe hallux valgus deformity in patients with rheumatoid arthritis (RA). However, with the progress of medical treatment of RA, joint preservation surgery has recently been performed. The aim of this study was to investigate the clinical and radiographic outcomes of modified Scarf osteotomy with medial capsule interposition for RA cases including severe destruction of the first MTP joint and to evaluate risk factors for recurrence...
May 2, 2018: Journal of Bone and Joint Surgery. American Volume
Carla Liedtke, Waldemar Kohl, Mariska Esther Kret, Katja Koelkebeck
BACKGROUND: Previous research has shown that context (e.g. culture) can have an impact on speed and accuracy when identifying facial expressions of emotion. Patients with a major depressive disorder (MDD) are known to have deficits in the identification of facial expressions, tending to give rather stereotypical judgments. While healthy individuals perceive situations which conflict with their own cultural values more negatively, this pattern would be even stronger in MDD patients, as their altered mood results in stronger biases...
February 2018: Journal of Affective Disorders
Namık Şahin, Gökhan Cansabuncu, Nazan Çevik, Oğuz Türker, Güven Özkaya, Yüksel Özkan
OBJECTIVES: The aim of this study was to compare clinical and radiological results of proximal crescentic osteotomy (PCO) and rotational scarf osteotomy performed in the treatment of hallux valgus. METHODS: A total of 57 consecutive patients (60 feet) with symptomatic hallux valgus deformity were randomly assigned to one of two groups. The PCO group consisted of 22 women and 5 men (30 feet) and the mean age was 43(±14.5) years. The scarf group consisted of 23 women and 7 men (30 feet) and the mean age was 40...
March 30, 2018: Acta Orthopaedica et Traumatologica Turcica
Anje Scarfe, Joanna Duncan, Ning Ma, Alun Cameron, David Rankin, Alex Karatassas, David Fletcher, David Watters, Guy Maddern
BACKGROUND: Analysis of a private insurer's administrative data set revealed significant variation in the length of hospital stay following hernia surgery. OBJECTIVES: This review examined factors influencing the performance of day surgery for inguinal, femoral and umbilical hernia repair in adults. DATA SOURCES: A systematic literature search was conducted in the PubMed, Embase and Cochrane Library databases to identify studies and clinical practice guidelines (CPGs) comparing same day hernia surgery to surgery followed by an overnight stay...
March 23, 2018: ANZ Journal of Surgery
Allison M Cummins, Rachel Smith, Christine Catling, Nicole Watts, Vanessa Scarf, Deborah Fox, Joanne Gray
No abstract text is available yet for this article.
June 2018: Midwifery
N O Elander, K Aughton, P Ghaneh, J P Neoptolemos, D H Palmer, T F Cox, F Campbell, E Costello, C M Halloran, J R Mackey, A G Scarfe, J W Valle, A C McDonald, R Carter, N C Tebbutt, D Goldstein, J Shannon, C Dervenis, B Glimelius, M Deakin, R M Charnley, A Anthoney, M M Lerch, J Mayerle, A Oláh, M W Büchler, W Greenhalf
BACKGROUND: Deoxycytidylate deaminase (DCTD) and ribonucleotide reductase subunit M1 (RRM1) are potential prognostic and predictive biomarkers for pyrimidine-based chemotherapy in pancreatic adenocarcinoma. METHODS: Immunohistochemical staining of DCTD and RRM1 was performed on tissue microarrays representing tumour samples from 303 patients in European Study Group for Pancreatic Cancer (ESPAC)-randomised adjuvant trials following pancreatic resection, 272 of whom had received gemcitabine or 5-fluorouracil with folinic acid in ESPAC-3(v2), and 31 patients from the combined ESPAC-3(v1) and ESPAC-1 post-operative pure observational groups...
April 2018: British Journal of Cancer
N O Elander, K Aughton, P Ghaneh, J P Neoptolemos, D H Palmer, T F Cox, F Campbell, E Costello, C M Halloran, J R Mackey, A G Scarfe, J W Valle, A C McDonald, R Carter, N C Tebbutt, D Goldstein, J Shannon, C Dervenis, B Glimelius, M Deakin, R M Charnley, Alan Anthoney, M M Lerch, J Mayerle, A Oláh, M W Büchler, W Greenhalf
BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) tumour expression may provide added value to human equilibrative nucleoside transporter-1 (hENT1) tumour expression in predicting survival following pyrimidine-based adjuvant chemotherapy. METHODS: DPD and hENT1 immunohistochemistry and scoring was completed on tumour cores from 238 patients with pancreatic cancer in the ESPAC-3(v2) trial, randomised to either postoperative gemcitabine or 5-fluorouracil/folinic acid (5FU/FA)...
April 2018: British Journal of Cancer
Damian Scarf, Ashley E Hinten
No abstract text is available yet for this article.
February 21, 2018: Pediatrics
John R Vokey, Randall K Jamieson, Jason M Tangen, Rachel A Searston, Scott W Allen
Scarf et al. (Proc Natl Acad Sci 113(40):11272-11276, 2016) demonstrated that pigeons, as with baboons (Grainger et al. in Science 336(6078):245-248, 2012; Ziegler in Psychol Sci. , 2013), can be trained to display several behavioural hallmarks of human orthographic processing. But, Vokey and Jamieson (Psychol Sci 25(4):991-996, 2014) demonstrated that a standard, autoassociative neural network model of memory applied to pixel maps of the words and nonwords reproduces all of those results...
May 2018: Animal Cognition
Gunaseelan Karunanithi, Rapole Pragna Sagar, Aswin Joy, Parthasarathy Vedasoundaram
Purpose: The diagnosis of cancer and its treatment can make patients psychologically distressed. The purpose of this study is to evaluate the level of psychological distress and social functioning in cancer patients and to assess the association of these parameters with the quality of life (QOL) experienced by the patient. Patients and Methods: All cancer patients attending palliative care clinic who can understand and speak English or Tamil language were taken into the study...
January 2018: Indian Journal of Palliative Care
M Curtin, E Murphy, C Bryan, P Moroney
BACKGROUND: Hallux valgus is a common condition with in excess of 120 procedures described in the literature for its correction. Traditionally, distal metatarsal osteotomies have been employed in the treatment of mild deformities, with proximal osteotomies being reserved for more severe presentations. The Scarf osteotomy without internal fixation allows large translations which can successfully correct severe hallux valgus deformities, without limitations related to screw placement. METHODS: This is a retrospective single surgeon case series performed over a three year period...
March 9, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Mun Chun Lai, Jerry Yongqiang Chen, Yeong Huei Ng, Hwei Chi Chong, Kevin Oon Thien Koo, Inderjeet Singh Rikhraj
BACKGROUND: Studies showed patients with hallux valgus also have tight gastrocnemius concomitantly. This study aims to investigate (1) prevalence of tight gastrocnemius in symptomatic hallux valgus (2) clinical and radiological outcomes of concomitant endoscopic gastrocnemius release with scarf osteotomy. METHODS: Between January 2011 to December 2013, 224 patients underwent hallux valgus surgery were evaluated. They were categorized into 2 groups: scarf osteotomy (n=195), scarf and endoscopic gastrocnemius release (combine, n=29)...
March 16, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Uğur Şaylı, Budak Akman, Altuğ Tanrıöver, Çiğdem Kaspar, Melih Güven, Turhan Özler
BACKGROUND: Intrinsically stable diaphyseal osteotomy gained popularity in recent years for symptomatic hallux valgus deformities. In this study, Scarf osteotomy results, in surgical management of moderate to severe hallux valgus, are presented. METHODS AND PATIENTS: Study group consisted of 40 feet of 32 (28 females, four males) patients surgically managed by Scarf osteotomy between September 2009 and 2011, with a mean age of 52,98 (range, 31-75) years at the time of surgery...
May 29, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Benjamin C Riordan, Tamlin S Conner, Johannes Thrul, Jayde A M Flett, Kate B Carey, Damian Scarf
BACKGROUND: The goal of Orientation Week is to help new students adjust to university life. However, it is a period when many new students engage in excessive alcohol consumption and where problematic drinking patterns may be established. OBJECTIVE: The objective is to determine whether returning students drink in a similar manner to students in their first-year of classes and whether Orientation Week drinking predicts semester drinking more strongly for first-year than returning students...
January 16, 2018: Substance Use & Misuse
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