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https://www.readbyqxmd.com/read/28726714/performance-of-a-novel-recycling-magnetic-flocculation-membrane-filtration-process-for-tetracycline-polluted-surface-water-treatment
#1
Yufei Wang, Hui Jia, Hongwei Zhang, Jie Wang, Wenjin Liu
A recycling magnetic flocculation membrane filtration (RMFMF) process integrating circulating coagulation, magnetic enhanced flocculation and membrane filtration was investigated for the treatment of surface water micro-polluted by tetracycline, a typical pharmaceutical and personal care product. A bench-scale experiment was conducted and several water quality parameters including turbidity, ultraviolet absorbance at 254 nm (UV254), total organic carbon and tetracycline concentration were evaluated, taking coagulation membrane filtration and magnetic flocculation membrane filtration processes as reference treatments...
July 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28724345/simultaneous-bilateral-total-knee-arthroplasty-in-hemophilia-is-it-recommended
#2
E Carlos Rodriguez-Merchan
Simultaneous bilateral total knee arthroplasty (TKA) is a potentially cost-saving manner of caring for patients with hemophilia who have bilateral symptomatic hemophilic knee arthropathy. Because factor VIII is used only once in bilateral TKA, it is performed in hemophilia to reduce costs. Areas covered: This article reviews the potential role of simultaneous bilateral TKA in patients with hemophilia. Expert commentary: Although two recent reports have mentioned the benefits of simultaneous bilateral TKA in patients with hemophilia, the data are still scant and preliminary...
July 20, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/28724129/association-of-cost-sharing-with-mental-health-care-use-involuntary-commitment-and-acute-care
#3
Bastian Ravesteijn, Eli B Schachar, Aartjan T F Beekman, Richard T J M Janssen, Patrick P T Jeurissen
Importance: A higher out-of-pocket price for mental health care may lead not only to cost savings but also to negative downstream consequences. Objective: To examine the association of higher patient cost sharing with mental health care use and downstream effects, such as involuntary commitment and acute mental health care use. Design, Setting, and Participants: This difference-in-differences study compared changes in mental health care use by adults, who experienced an increase in cost sharing, with changes in youths, who did not experience the increase and thus formed a control group...
July 19, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28720812/silicon-nanocrystal-based-photonic-crystal-slabs-with-broadband-and-efficient-directional-light-emission
#4
L Ondič, M Varga, I Pelant, J Valenta, A Kromka, R G Elliman
Light extraction from a thin planar layer can be increased by introducing a two-dimensional periodic pattern on its surface. This structure, the so-called photonic crystal (PhC) slab, then not only enhances the extraction efficiency of light but can direct the extracted emission into desired angles. Careful design of the structures is important in order to have a spectral overlap of the emission with extraction (leaky) modes. We show that by fabricating PhC slabs with optimized dimensions from silicon nanocrystals (SiNCs) active layers, the extraction efficiency of vertical light emission from SiNCs at a particular wavelength can be enhanced ∼ 11 times compared to that of uncorrugated SiNCs-rich layer...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720446/acceptability-of-multipurpose-human-papillomavirus-vaccines-among-providers-and-mothers-of-adolescent-girls-a-mixed-methods-study-in-five-countries
#5
Nadja A Vielot, Shoshana K Goldberg, Gregory Zimet, Sara B Smith, Mary Anne McDonald, Silvina Ramos, Karen Morgan, Chan Joo Kim, Karin L Richter, Merce Peris, Kevin J Whaley, Jennifer S Smith
INTRODUCTION: Multipurpose vaccines (MPVs) could be formulated to prevent multiple sexually transmitted infections simultaneously. Little is known about acceptability of MPVs among vaccine health care providers (HCPs) or mothers of adolescent girls. METHODS: 151 adolescent vaccine providers and 118 mothers of adolescent girls aged 9-14 were recruited from five geographically-diverse countries: Argentina, Malaysia, South Africa, South Korea, and Spain. We assessed providers' preferences for single-purpose human papillomavirus (HPV) vaccine versus MPVs (including HPV+herpes simplex virus (HSV)-2, HPV+HIV, or HPV+HSV-2+HIV) via quantitative surveys...
June 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/28714799/in-silico-approaches-to-identify-novel-myeloid-cell-leukemia-1-mcl-1-inhibitors-for-treatment-of-cancer
#6
Ji-Xia Ren, Cheng-Ping Li, Xiu-Ling Zhou, Xue-Song Cao, Yong Xie
Myeloid cell leukemia-1 (Mcl-1) has been a validated and attractive target for cancer therapy. Over-expression of Mcl-1 in many cancers allows cancer cells to evade apoptosis and contributes to the resistance to current chemotherapeutics. Here, we identified new Mcl-1 inhibitors using a multi-step virtual screening approach. First, based on two different ligand-receptor complexes, 20 pharmacophore models were established by simultaneously using "Receptor-Ligand Pharmacophore Generation" method and manual build feature method, and then carefully validated by a test database...
July 17, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28714419/design-of-multi-target-agents-for-the-treatment-of-alzheimer-s-disease-based-on-tacrine
#7
Hongzhi Lin, Qi Li, Kai Gu, Jie Zhu, Xueyang Jiang, Yao Chen, Haopeng Sun
Alzheimer's disease (AD) is one of the most common forms of dementia in elderly people. To date, efficacious therapeutic agent for the treatment of AD is still very limited, so it has long been a challenging and attractive task to discover new anti-AD drugs. Considering the multifactorial nature of AD, recently, the concept of multi-target-directed ligands (MTDLs) has emerged as a new strategy for designing therapeutic agents on AD. MTDLs are believed to exert their effects through simultaneously affecting multiple targets which contribute to etiology of AD...
July 17, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/28712623/valid-outcome-measures-in-care-for-older-people-comparing-the-ascot-and-the-icecap-o
#8
Mariska Q N Hackert, Job van Exel, Werner B F Brouwer
BACKGROUND: Limited health care budgets and population aging result in a need to compare care services on their benefits and costs. Because services for older people often aim to improve multiple life aspects, valid measures are needed to examine their benefits on individuals' health and well-being simultaneously. Two measures may meet this end: the Adult Social Care Outcomes Toolkit (ASCOT) and the ICEpop CAPability measure for Older people (ICECAP-O). OBJECTIVES: To compare the validity of both measures, the ASCOT and the ICECAP-O...
July 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28712512/higher-pain-level-and-lower-functional-capacity-are-associated-with-the-number-of-altered-kinematics-in-women-with-patellofemoral-pain
#9
Deisi Ferrari, Ronaldo Valdir Briani, Danilo de Oliveira Silva, Marcella Ferraz Pazzinatto, Amanda Schenatto Ferreira, Neri Alves, Fábio Mícolis de Azevedo
This study investigated whether women with patellofemoral pain (PFP) present kinematic alterations in proximal, local, and distal factors simultaneously, and determined the association between the number of kinematic alterations, pain level, and functional status. A three-dimensional motion analysis system was used to analyze the peak hip adduction, peak knee flexion, and peak rearfoot eversion, addressing the proximal, local, and distal factors, respectively, in fifty women. Functional status and pain level were assessed using the anterior knee pain scale (AKPS) and a visual analogic scale...
July 10, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28712104/do-bacteria-isolated-from-icu-patients-eskape-antibiotic-treatment-in-vitro-susceptibility-of-the-enterobacteriaceae-family-to-tigecycline
#10
Katarzyna Talaga-Ćwiertnia, Paweł Krzyściak, Małgorzata Bulanda
BACKGROUND: Enterobacteriaceae are currently causing the majority of healthcare-associated infections (HAI) and simultaneously expressing increasing levels of antibiotic resistance. The purpose of this study is to assess the in vitro sensitivity of MDR strains from the family Enterobacteriaceae to tigecycline in relation to their origin from patients hospitalized in intensive care units (ICUs) and non-ICUs. METHODS: The study involved 156 clinically-significant strains of the Enterobacteriaceae family isolated from patients with cIAIs and/or cSSSIs hospitalized in ICUs and other surgical departments...
July 16, 2017: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/28711825/autonomous-electrochemical-biosensors-a-new-vision-to-direct-methanol-fuel-cells
#11
M Goreti F Sales, Lúcia Brandão
A new approach to biosensing devices is demonstrated aiming an easier and simpler application in routine health care systems. Our methodology considered a new concept for the biosensor transducing event that allows to obtain, simultaneously, an equipment-free, user-friendly, cheap electrical biosensor. The use of the anode triple-phase boundary (TPB) layer of a passive direct methanol fuel cell (DMFC) as biosensor transducer is herein proposed. For that, the ionomer present in the anode catalytic layer of the DMFC is partially replaced by an ionomer with molecular recognition capability working as the biorecognition element of the biosensor...
July 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28710699/examining-early-childhood-health-outcomes-of-children-born-late-preterm-in-urban-manitoba
#12
Leah K Crockett, Marni D Brownell, Maureen I Heaman, Chelsea A Ruth, Heather J Prior
Objective The late preterm population [34-36 weeks gestational age (GA)] is known to incur increased morbidity in the infancy stage compared to the population born at term (39-41 weeks GA). This study aimed to examine the health of these children during their early childhood years, with specific attention to the role of socioeconomic status. Methods A retrospective cohort study was conducted using data from the Manitoba Centre for Health Policy, including all live-born children born at 34-36 and 39-41 weeks GA in urban Manitoba between 2000 and 2005 (n = 28,100)...
July 14, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28710628/%C3%AE-sitosterol-bioconversion-to-androstenedione-in-microtiter-plates
#13
Marco P C Marques, Pedro Fernandes
Microtiter plates are routinely used as low-cost miniaturized bioreactors due to the large number of experiments that can be conducted simultaneously under similar conditions and replicate all functions of bench-scale reactors at dramatically smaller volumes. These plates, due to the standard footprint, can be integrated with liquid-handling systems and associated equipment expanding considerably their application and use. However, care has to be taken to operate the microtiter plates in optimized mixing and oxygen transfer conditions, preventing medium evaporation in prolonged experiment runs...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28709495/unusual-case-of-coexistent-pulmonary-cryptococcosis-and-tuberculosis-in-an-immuno-competent-host
#14
Sunila Jain, Vrushali Mahajan, Arvind Kumar
Coexistence of pulmonary cryptococcosis with other infections has commonly been described in immuno-suppressed individuals. In immuno-competent hosts, such coexistence is rare and mostly described in disseminated disease or uncommonly involving different sites. The simultaneous coinfection of cryptococcosis and tuberculosis of lung in an immuno-competent host is extremely rare with only one previously reported case in the literature. This is the second such case and the first to be reported in India. We describe a case of a 36-year-old immuno-competent male who presented with haemoptysis and cough...
July 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28703878/obstetric-hemorrhage-and-safe-blood-for-transfusion-in-ethiopia-the-challenges-of-bridging-the-gap
#15
REVIEW
Addisalem Taye Makuria, Daniel Gebremichael, Habtemariam Demoz, Azmach Hadush, Yetmgeta Abdella, Yemane Berhane, Naynesh Kamani
BACKGROUND: Obstetric hemorrhage is a leading cause of maternal death in sub-Saharan Africa, and the shortage of blood for transfusion is a contributory factor. In Ethiopia, the National Blood Bank Service continues to be confronted with challenges in its efforts to ensure the availability of blood for health care facilities. This paper reviews the available data on the contribution of obstetric hemorrhage to maternal mortality and examines the current status of the blood supply in Ethiopia...
July 13, 2017: Transfusion
https://www.readbyqxmd.com/read/28702773/can-exercise-or-physical-activity-help-improve-postnatal-depression-and-weight-loss-a-systematic-review
#16
REVIEW
Maryam Saligheh, Daniel Hackett, Philip Boyce, Stephen Cobley
Despite exercise or physical activity (PA) being effective on depression and weight management generally, its effectiveness remains uncertain during postpartum. This systematic review aimed to determine the efficacy of exercise or PA interventions on postnatal depression (PND) and weight loss, with a subsequent aim to identify more effective intervention approaches. Using PRISMA guidelines, data searches conducted across six databases. Nine studies fulfilled our inclusion criteria. Based on identified studies (some with high-quality RCT designs), there was inconsistency as to whether exercise or PA simultaneously reduced PND symptoms and assisted weight loss (or related body composition indices)...
July 12, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28702456/growing-pains-at-hospitals-opportunities-and-issues-of-service-expansion-in-maximum-care
#17
Juergen Hinkelmann, Joachim Paul Hasebrook, Thomas Volkert, Klaus Hahnenkamp
PURPOSE: Due to the demographic change morbidity raises the demand for medical hospital services as well as a need for medical specialization, while economic and human resources are diminishing. Unlike other industries hospitals do not have sufficient data and adequate models to relate growing demands and increasing performance to growth in staff capacity and to increase in staff competences. METHOD: Based on huge medical data sample covering the years from 2010 to 2014 with more than 150,000 operations of the Department for Anesthesiology at the University Hospital Muenster, Germany, comparisons are drawn between the development of medical services and the development of personnel capacity and expertise...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28700206/drug-porous-silicon-dual-luminescent-system-for-monitoring-and-inhibition-of-wound-infection
#18
Xisheng Chen, Fangjie Wo, Yao Jin, Jie Tan, Yan Lai, Jianmin Wu
Wound monitoring and curing is of great importance in biomedical research. This work created a smart bandage that can simultaneously monitor and inhibit wound infection. The main components of the smart bandage are luminescent porous silicon (LuPSi) particles loaded with ciprofloxacin (CIP). This dual luminescent system can undergo accelerated fluorescent color change from red to blue upon the stimulation of reactive oxygen species (ROS) and elevated pH, which are main biomarkers in the infected wound. The mechanism behind the chemical-triggered fluorescent color change was studied in detail...
July 17, 2017: ACS Nano
https://www.readbyqxmd.com/read/28697869/perioperative-mortality-in-cats-and-dogs-undergoing-spay-or-castration-at-a-high-volume-clinic
#19
J K Levy, K M Bard, S J Tucker, P D Diskant, P A Dingman
High volume spay-neuter (spay-castration) clinics have been established to improve population control of cats and dogs to reduce the number of animals admitted to and euthanazed in animal shelters. The rise in the number of spay-neuter clinics in the USA has been accompanied by concern about the quality of animal care provided in high volume facilities, which focus on minimally invasive, time saving techniques, high throughput and simultaneous management of multiple animals under various stages of anesthesia...
June 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28697503/update-of-sepsis-in-the-intensive-care-unit
#20
Kelly Roveran Genga, James A Russell
Sepsis, the most common cause of admission to an intensive care unit (ICU), has had an increased incidence and prevalence over the last years with a simultaneous decrease in its short-term mortality. Sepsis survivors are more frequently discharged from hospital and often experience long-term outcomes such as late mortality, immune dysfunction, secondary infections, impaired quality of life, and unplanned readmissions. Early recognition and management of sepsis have challenged emergency care and critical care physicians and nurses...
July 12, 2017: Journal of Innate Immunity
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