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https://www.readbyqxmd.com/read/29457872/simple-method-for-the-determination-of-personal-care-product-ingredients-in-lettuce-by-ultrasound-assisted-extraction-combined-with-solid-phase-microextraction-followed-by-gc-ms
#1
Jerónimo Cabrera-Peralta, Araceli Peña-Alvarez
A simple method for the simultaneous determination of personal care product ingredients: galaxolide, tonalide, oxybenzone, 4-methylbenzyliden camphor, padimate-o, 2-ethylhexyl methoxycinnamate, octocrylene, triclosan and methyl triclosan in lettuce by ultrasound-assisted extraction combined with solid-phase microextraction followed by gas chromatography with mass spectrometry was developed. Lettuce was directly extracted by ultrasound-assisted extraction with methanol, this extract was combined with water, extracted by solid-phase microextraction in immersion mode and analyzed by gas chromatography with mass spectrometry...
February 19, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29455000/the-impact-of-increased-number-of-low-risk-deliveries-on-maternal-and-neonatal-outcomes-a-retrospective-cohort-study-in-finland-in-2011-2015
#2
Elina Karalis, Anna-Maija Tapper, Mika Gissler, Veli-Matti Ulander
OBJECTIVES: Our aim was to demonstrate the influence of increased number of low-risk deliveries on obstetric and neonatal outcome. STUDY DESIGN: The study hospital was Kätilöopisto Maternity Hospital in Helsinki. Simultaneously, we studied all three delivery units in the Helsinki region in the population-based analysis. The study population was singleton hospital deliveries occurring between 2011 and 2012, and 2014-2015. The study hospital included 11 237 and 15 637 births and the population-based group included 28 950 and 27 979 births...
February 14, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29451942/incidence-of-and-risk-factors-for-knee-collateral-ligament-injuries-with-proximal-tibia-fractures-a-study-of-32-441-patients
#3
Andre M Samuel, Pablo J Diaz-Collado, Lauren K Szolomayer, Daniel H Wiznia, Wayne W Chan, Adam M Lukasiewicz, Bryce A Basques, Daniel D Bohl, Jonathan N Grauer
Proximal tibia fractures are associated with concurrent collateral ligament injuries. Failure to recognize these injuries may lead to chronic knee instability. The purpose of this study was to identify risk factors for concurrent collateral ligament injuries with proximal tibia fractures and their association with inpatient outcomes. A total of 32,441 patients with proximal tibia fractures were identified in the 2011-2012 National Trauma Data Bank. A total of 1445 (4.5%) had collateral ligament injuries, 794 (2...
February 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29451781/multiple-snps-detection-based-on-lateral-flow-assay-for-phenylketonuria-diagnostic
#4
Xiaonan Liu, Chao Zhang, Kewu Liu, Han Wang, Chaoxia Lu, Hang Li, Kai Hua, Juanli Zhu, Wenli Hui, Yali Cui, Xue Zhang
Single nucleotide polymorphisms (SNPs) are closely related to genetic diseases, but current SNP detection methods, such as DNA microarrays that include tedious procedures and expensive, sophisticated instruments, are unable to perform rapid SNPs detection in clinical practice, especially for those multiple SNPs related to genetic diseases. In this study, we report a sensitive, low cost, and easy-to-use point-of-care testing (POCT) system formed by combining amplification refractory mutation system (ARMS) polymerase chain reaction with gold magnetic nanoparticles (GMNPs) and lateral flow assay (LFA) noted as the ARMS-LFA system, which allow us to use a uniform condition for multiple SNPs detection simultaneously...
February 16, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29450194/avoiding-arterial-hypotension-in-preterm-neonates-ahip-a-single-center-randomised-controlled-study-investigating-simultaneous-near-infrared-spectroscopy-measurements-of-cerebral-and-peripheral-regional-tissue-oxygenation-and-dedicated-interventions
#5
Gerhard Pichler, Nina Höller, Nariae Baik-Schneditz, Bernhard Schwaberger, Lukas Mileder, Jasmin Stadler, Alexander Avian, Jasmin Pansy, Berndt Urlesberger
Introduction: Up to 50% of preterm infants admitted to intensive care units require cardiocirculatory support. The aim of the present study was to assess whether simultaneous monitoring of cerebral tissue oxygenation index (cTOI) and peripheral tissue oxygenation index (pTOI) using near-infrared spectroscopy (NIRS) in combination with dedicated intervention guidelines may help avoiding arterial hypotension and catecholamine administration in preterm neonates. Study design: Preterm neonates <37 weeks of gestation were included in a single center randomized controlled study...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29448192/impact-of-enzymatic-hydrolysis-on-the-quantification-of-total-urinary-concentrations-of-chemical-biomarkers
#6
Prabha Dwivedi, Xiaoliu Zhou, Tolar G Powell, Antonia M Calafat, Xiaoyun Ye
Human exposure to consumer and personal care products chemicals such as phenols, including parabens and other antimicrobial agents, can be assessed through biomonitoring by quantifying urinary concentrations of the parent chemical or its metabolites, often after hydrolysis of phase II conjugates. Developing suitable analytical methods for the concurrent quantification of multiple exposure biomarkers is challenging because optimal conditions for the hydrolysis of such conjugates (e.g., O-glucuronides, N-glucuronides, sulfates) may differ depending on the biomarker...
February 12, 2018: Chemosphere
https://www.readbyqxmd.com/read/29447221/how-does-the-interaction-radius-affect-the-performance-of-intervention-on-collective-behavior
#7
Caiyun Wang, Jing Han
The interaction radius r plays an important role in the collective behavior of many multi-agent systems because it defines the interaction network among agents. For the topic of intervention on collective behavior of multi-agent systems, does r also affect the intervention performance? In this paper we study whether it is easier to change the convergent heading of the group by adding some special agents (called shills) into the Vicsek model when r is larger (or smaller). Two kinds of shills are considered: fixed-heading shills (like leaders that never change their headings) and evolvable-heading shills (like normal agents but with carefully designed initial headings)...
2018: PloS One
https://www.readbyqxmd.com/read/29447023/designing-a-low-cost-single-supply-ecg-system-for-suppression-of-movement-artifact-from-contaminated-magnetocardiogram
#8
Rajesh Patel, S Sengottuvel, K Gireesan, M P Janawadkar, T S Radhakrishnan
Measurement of the late potentials and His-bundle activity is crucial for many clinical studies using the noncontact and noninvasive magnetocardiography (MCG) technique; these weak signals are extracted by averaging many cardiac cycles aligned using the R-peak of the cardiac cycle identified using an electrocardiography (ECG) lead. ECG is measured simultaneously with MCG using a conventional dual-supply ECG amplifier, which requires either two separate batteries or a single battery with a switching voltage inverter circuit for its proper operation...
February 1, 2018: SLAS Technology
https://www.readbyqxmd.com/read/29443918/error-modelling-for-multi-sensor-measurements-in-infrastructure-free-indoor-navigation
#9
Laura Ruotsalainen, Martti Kirkko-Jaakkola, Jesperi Rantanen, Maija Mäkelä
The long-term objective of our research is to develop a method for infrastructure-free simultaneous localization and mapping (SLAM) and context recognition for tactical situational awareness. Localization will be realized by propagating motion measurements obtained using a monocular camera, a foot-mounted Inertial Measurement Unit (IMU), sonar, and a barometer. Due to the size and weight requirements set by tactical applications, Micro-Electro-Mechanical (MEMS) sensors will be used. However, MEMS sensors suffer from biases and drift errors that may substantially decrease the position accuracy...
February 14, 2018: Sensors
https://www.readbyqxmd.com/read/29440015/self-rated-worry-in-acute-care-telephone-triage-a-mixed-methods-study
#10
Hejdi Gamst-Jensen, Linda Huibers, Kristoffer Pedersen, Erika F Christensen, Annette K Ersbøll, Freddy K Lippert, Ingrid Egerod
BACKGROUND: Telephone triage is used to assess acute illness or injury. Clinical decision making is often assisted by triage tools that lack callers' perspectives. This study analysed callers' perception of urgency, defined as degree of worry in acute care telephone calls. AIM: To explore the caller's ability to quantify their degree of worry, the association between degree of worry and variables related to the caller, the effect of degree of worry on triage outcome, and the thematic content of the caller's worry...
February 12, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29438381/monitoring-tumor-response-to-the-vascular-disrupting-agent-ckd-516-in-a-rabbit-vx2-intramuscular-tumor-model-using-pet-mri-simultaneous-evaluation-of-vascular-and-metabolic-parameters
#11
Su Yeon Ahn, Jin Mo Goo, Kyung Hee Lee, Seunggyun Ha, Jin Chul Paeng
OBJECTIVES: To determine whether the CKD-516 produces a significant change in vascular and metabolic parameters in PET/MRI. MATERIALS AND METHODS: With institutional Animal Care and Use Committee approval, 18 VX2 carcinoma tumors implanted in bilateral back muscles of 9 rabbits were evaluated. Serial PET/MRI were performed before, 4 hours after and 1-week after vascular disrupting agent, CKD-516 at a dose of 0.7 mg/kg (treated group, n = 10) or saline (control group, n = 8) administration...
2018: PloS One
https://www.readbyqxmd.com/read/29436699/-bipolar-disorder-and-alcohol-use-disorder-practical-recommendations-for-treatment-based-on-a-literature-review
#12
A T Spijker, J van Zaane, M A Koenders, R Hoekstra, R W Kupka
A fairly large proportion (25-50%) of patients with bipolar disorder (bd) also suffer from comorbid alcohol use disorder (aud). However, little is known how this type of morbidity should be treated. It is also unclear whether the current guidelines on bd have been influenced by aud.<br/> AIM: To provide an overview of recent literature concerning the diagnosis and treatment of comorbid bd and aud.<br/> METHOD: We systematically reviewed studies that have addressed three treatment options for this group of patients: pharmaco-therapy, psychological interventions and self-management techniques...
2018: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29436552/real-time-multiplexed-pcr-using-surface-enhanced-raman-spectroscopy-in-a-thermoplastic-chip
#13
S M Restaino, I M White
Surface enhanced Raman spectroscopy (SERS) has the potential to enable point-of-care sensing across the spectrum of chemical and biological analytes. In diagnostic assays, SERS has been demonstrated to increase the multiplexing density while reducing the burden of fluorescence hardware. One particular application of interest is the use of SERS to provide a multiplexed optical read-out following polymerase chain reaction (PCR). To date, however, the reported PCR-SERS assays require endpoint mixing with a plasmonic nanoparticle solution for detection, thus adding manual steps and preventing real-time, quantitative PCR...
February 13, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29436285/m%C3%A3-ni%C3%A3-re-s-disease-pathophysiology-endolymphatic-sac-immunohistochemical-study-of-aquaporin-2-v2r-vasopressin-receptor-nkcc2-and-trpv4
#14
Marc-Henri Asmar, Louis Gaboury, Issam Saliba
Objectives Endolymphatic sac (ELS) pathophysiology in Ménière's disease (MD) remains poorly understood. We identified from the literature a group of proteins expressed on the ELS and involved in endolymph volume regulation: aquaporin-2 (AQP2), vasopressin receptor V2R, sodium potassium chloride cotransporter 2 (NKCC2), and transient receptor potential cation channel V4 (TRPV4). Our objective was to determine whether their ELS expression was altered in MD, to better understand the pathophysiology of endolymphatic hydrops...
February 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29435580/association-of-prenatal-ultrasonography-and-autism-spectrum-disorder
#15
N Paul Rosman, Rachel Vassar, Gheorghe Doros, James DeRosa, Allison Froman, Audrey DiMauro, Sherry Santiago, Jodi Abbott
Importance: The prevalence of autism spectrum disorder (ASD) has been increasing rapidly, with current estimates of 1 in 68 children affected. Simultaneously, use of prenatal ultrasonography has increased substantially, with limited investigation into its safety and effects on brain development. Animal studies have demonstrated that prenatal ultrasonography can adversely affect neuronal migration. Objective: To quantify prenatal ultrasound exposure by the frequency, timing, duration, and strength of ultrasonographic scans in children with later ASD, developmental delay, and typical development...
February 12, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29433505/why-nutrition-education-is-inadequate-in-the-medical-curriculum-a-qualitative-study-of-students-perspectives-on-barriers-and-strategies
#16
Victor Mogre, Fred C J Stevens, Paul A Aryee, Anthony Amalba, Albert J J A Scherpbier
BACKGROUND: The provision of nutrition care by doctors is important in promoting healthy dietary habits, and such interventions can lead to reductions in disease morbidity, mortality, and medical costs. However, medical students and doctors report inadequate nutrition education and preparedness during their training at school. Previous studies investigating the inadequacy of nutrition education have not sufficiently evaluated the perspectives of students. In this study, students' perspectives on doctors' role in nutrition care, perceived barriers, and strategies to improve nutrition educational experiences are explored...
February 12, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29432773/identifying-patterns-of-general-practitioner-service-utilisation-and-their-relationship-with-potentially-preventable-hospitalisations-in-people-with-diabetes-the-utility-of-a-cluster-analysisapproach
#17
Ninh Thi Ha, Mark Harris, David Preen, Suzanne Robinson, Rachael Moorin
AIMS: We aimed to characterise use of general practitioners (GP) simultaneously across multiple attributes in people with diabetes and examine its impact on diabetes related potentially preventable hospitalisations (PPHs). METHODS: Five-years of panel data from 40,625 adults with diabetes were sourced from Western Australian administrative health records. Cluster analysis (CA) was used to group individuals with similar patterns of GP utilisation characterised by frequency and recency of services...
February 9, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29431872/interventions-to-prevent-hypothermia-at-birth-in-preterm-and-or-low-birth-weight-infants
#18
REVIEW
Emma M McCall, Fiona Alderdice, Henry L Halliday, Sunita Vohra, Linda Johnston
BACKGROUND: Newborn admission temperature is a strong predictor of outcomes across all gestations. Hypothermia immediately after birth remains a worldwide issue and, if prolonged, is associated with harm. Keeping preterm infants warm is difficult even when recommended routine thermal care guidelines are followed in the delivery room. OBJECTIVES: To assess the efficacy and safety of interventions designed for prevention of hypothermia in preterm and/or low birth weight infants applied within 10 minutes after birth in the delivery room, compared with routine thermal care or any other single/combination of intervention(s) also designed for prevention of hypothermia in preterm and/or low birth weight infants applied within 10 minutes after birth in the delivery room...
February 12, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29431426/strand-displacement-amplification-reaction-on-quantum-dot-encoded-silica-bead-for-visual-detection-of-multiplex-micrornas
#19
Xiaojun Qu, Haojun Jin, Yuqian Liu, Qingjiang Sun
The combination of microbead array, isothermal amplification and molecular signaling enables the continuous development of next-generation molecular diagnostic techniques. Herein we reported the implementation of nicking endonuclease-assisted strand displacement amplification reaction on quantum dots-encoded microbead (Qbead), and demonstrated its feasibility for multiplexed miRNA assay in real sample. The Qbead featured with well-defined core-shell superstructure with dual-colored quantum dots loaded in silica core and shell, respectively, exhibiting remarkably high optical encoding stability...
February 12, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29429430/review-of-implementation-strategies-to-change-healthcare-provider-behaviour-in-the-emergency-department
#20
Kerstin de Wit, Janet Curran, Brent Thoma, Shawn Dowling, Eddy Lang, Nebojsa Kuljic, Jeffrey J Perry, Laurie Morrison
OBJECTIVES: Advances in emergency medicine research can be slow to make their way into clinical care, and implementing a new evidence-based intervention can be challenging in the emergency department. The Canadian Association of Emergency Physicians (CAEP) Knowledge Translation Symposium working group set out to produce recommendations for best practice in the implementation of a new science in Canadian emergency departments. METHODS: A systematic review of implementation strategies to change health care provider behaviour in the emergency department was conducted simultaneously with a national survey of emergency physician experience...
February 12, 2018: CJEM
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