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https://www.readbyqxmd.com/read/27759931/managing-osteoporosis-in-patients-on-long-term-bisphosphonate-treatment-report-of-a-task-force-of-the-american-society-for-bone-and-mineral-research
#1
Robert A Adler, Ghada El-Hajj Fuleihan, Douglas C Bauer, Pauline M Camacho, Bart L Clarke, Gregory A Clines, Juliet E Compston, Matthew T Drake, Beatrice J Edwards, Murray J Favus, Susan L Greenspan, Ross McKinney, Robert J Pignolo, Deborah E Sellmeyer
No abstract text is available yet for this article.
October 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/27496319/1-alpha-25-dihydroxyvitamin-d3-alters-the-pharmacokinetics-of-mycophenolic-acid-in-renal-transplant-recipients-by-regulating-two-extrahepatic-udp-glucuronosyltransferases-1a8-and-1a10
#2
Xiaoliang Wang, Hongwei Wang, Bing Shen, Brian R Overholser, Bruce R Cooper, Yinghao Lu, Huamei Tang, Chongzhi Zhou, Xing Sun, Lin Zhong, Murray J Favus, Brian S Decker, Wanqing Liu, Zhihai Peng
Mycophenolic acid (MPA) is an important immunosuppressant broadly used in renal transplantation. However, the large inter-patient variability in mycophenolic acid (MPA) pharmacokinetics (PK) limits its use. We hypothesize that extrahepatic metabolism of MPA may have significant impact on MPA PK variability. Two intestinal UDP-glucuronosyltransferases 1A8 and 1A10 plays critical role in MPA metabolism. Both in silico and previous genome-wide analyses suggested that vitamin D (VD) may regulate intestinal UGT1A expression...
July 19, 2016: Translational Research: the Journal of Laboratory and Clinical Medicine
https://www.readbyqxmd.com/read/26773616/leprosy-in-the-bible
#3
Andrzej Grzybowski, Małgorzata Nita
For many years, the biblical term tzaraat has referred to leprosy. In fact, the disease or diseases described under this name have no relationship to leprosy, as it was known in the Middle Ages or today; moreover, the term referred not only to skin disease, but also to the state of the ritual impurity and punishment for the sins. Although the real nature of tzaraat remains unknown, the differential diagnosis might include the following: Psoriasis, seborrheic dermatitis, favus, dermatophyte infections, nummular dermatitis, atopic dermatitis, pityriasis rosea, crusted scabies, syphilis, impetigo, sycosis barbae, alopecia areata, furuncles, scabies, neurodermatitis, scarlet fever, lupus erythematosus, lichen sclerosus et atrophicus, folliculitis decalvans, morphea, sarcoidosis, and lichen planopilaris...
January 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/26649420/-a-recurrent-case-of-adult-favus-successfully-treated-with-terbinafine
#4
Deniz Erkan, İlkay Kolukırık, Alpaslan Acar, Hazal Kandemir, Macit İlkit
Favus or tinea capitis favosa, is a chronic inflammatory dermatophytosis of the scalp. The disease is particularly common in children aged 6 to 10 years, more often in boys, and it also occurs in adults. Human-to-human transmission is therefore possible. Anthropophilic Trichophyton schöenleinii is responsible for over 95% of favus cases. In addition, there are rare cases of anthropophilic T.violaceum, zoophilic (T.verrucosum, T.quinckeanum, and Microsporum canis) and geophilic M.gypseum species recorded as agents of favus...
October 2015: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/26641140/the-complete-mitochondrial-genome-of-mastacembelus-aculeatus-cypriniformes-mastacembelidae-from-the-pearl-river-china
#5
Shi-Bin Xiao, Ji-Jia Sun, Zi-Tuo Yang, Mei Liu, Yi-Shu Liao, Bing-Qian Lu, Hui-Rong Yang, Li Liu
In this paper, the complete mitochondrial DNA (mtDNA) sequence of Mastacembelus aculeatus was determined. The mitochondrial genome is 16 543 bp in length, including 13 protein-coding genes, 2 ribosomal RNAs (rRNAs), 22 transfer RNAs (tRNAs), and a non-coding control region as those found in other vertebrates, with the gene identical to that of typical vertebrates. The overall base composition of the heavy strand is 30.0% A, 26.4% T, 14.8% C, and 28.7% G, with an AT bias of 56.49%. Phylogeny of M. aculeatus suggested more close relationship with Mastacembelus armatus and Mastacembelus favus...
December 7, 2015: Mitochondrial DNA
https://www.readbyqxmd.com/read/26350171/managing-osteoporosis-in-patients-on-long-term-bisphosphonate-treatment-report-of-a-task-force-of-the-american-society-for-bone-and-mineral-research
#6
REVIEW
Robert A Adler, Ghada El-Hajj Fuleihan, Douglas C Bauer, Pauline M Camacho, Bart L Clarke, Gregory A Clines, Juliet E Compston, Matthew T Drake, Beatrice J Edwards, Murray J Favus, Susan L Greenspan, Ross McKinney, Robert J Pignolo, Deborah E Sellmeyer
Bisphosphonates (BPs) are the most commonly used medications for osteoporosis. This ASBMR report provides guidance on BP therapy duration with a risk-benefit perspective. Two trials provided evidence for long-term BP use. In the Fracture Intervention Trial Long-term Extension (FLEX), postmenopausal women receiving alendronate for 10 years had fewer clinical vertebral fractures than those switched to placebo after 5 years. In the HORIZON extension, women who received 6 annual infusions of zoledronic acid had fewer morphometric vertebral fractures compared with those switched to placebo after 3 years...
January 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/26278397/use-of-uhplc-high-resolution-orbitrap-mass-spectrometry-to-investigate-the-genes-involved-in-the-production-of-secondary-metabolites-in-aspergillus-flavus
#7
Natalia Arroyo-Manzanares, José Diana Di Mavungu, Valdet Uka, Svetlana V Malysheva, Jeffrey W Cary, Kenneth C Ehrlich, Lynn Vanhaecke, Deepak Bhatnagar, Sarah De Saeger
The fungus Aspergillus flavus is known for its ability to produce the toxic and carcinogenic aflatoxins in food and feed. While aflatoxins are of most concern, A. flavus is predicted to be capable of producing many more metabolites based on a study of its complete genome sequence. Some of these metabolites could be of great importance in food and feed safety. Here we describe an analytical methodology based on Orbitrap HRMS technology that allows the untargeted determination of fungal metabolites, in support of the study of the function of genes involved in secondary metabolism in fungi...
2015: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/26259050/disseminated-favus-caused-by-microsporum-gypseum-in-a-patient-with-systemic-lupus-erythematosus
#8
Tutyana Sanusi, Jin Gong, Xia Wang, Mengjie Zhao, Yun Zhao, Xiangjie An, Chunsen Wang, Changzheng Huang, Siyuan Chen
No abstract text is available yet for this article.
February 2016: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/26149460/tert-polymorphism-rs2736100-c-is-associated-with-egfr-mutation-positive-non-small-cell-lung-cancer
#9
Rongrong Wei, Lan Cao, Hengying Pu, Hongwei Wang, Yonglan Zheng, Xiaomin Niu, Xiaoling Weng, Hong Zhang, Murray J Favus, Lanjun Zhang, Weihua Jia, Yixin Zeng, Christopher I Amos, Shun Lu, Hui-Yun Wang, Yun Liu, Wanqing Liu
PURPOSE: EGF receptor (EGFR) mutation-positive (EGFRmut(+)) non-small cell lung cancer (NSCLC) may be a unique orphan disease. Previous studies suggested that the telomerase reverse transcriptase (TERT) gene polymorphism is associated with demographic and clinical features strongly associated with EGFR mutations, for example, adenocarcinoma histology, never-smoking history, and female gender. We aim to test the association between TERT polymorphism and EGFRmut(+) NSCLC. EXPERIMENTAL DESIGN: We conducted a genetic association study in Chinese patients with NSCLC (n = 714) and healthy controls (n = 2,520), between the rs2736100 polymorphism and EGFRmut(+) NSCLC...
November 15, 2015: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/25756741/evolution-of-tinea-capitis-in-the-nanchang-area-southern-china-a-50-year-survey-1965-2014
#10
Ping Zhan, Chengfang Geng, Zhihua Li, Yun Jin, Qing Jiang, Li Tao, Yunpeng Luo, Zhiwei Xiong, Shaoxi Wu, Dongmei Li, Weida Liu, G Sybren de Hoog
Tinea capitis remains a common public health problem worldwide especially in developing areas. Aetiologic agents and clinical pattern vary with geography and history of socioeconomic conditions. Three community surveys and a prospective study were carried out over the past 50 years (1965-2014) in the Qingyunpu District of Nanchang, Southern China. Clinical presentation and spectrum of aetiological agents were monitored to understand the evolution of tinea capitis. In 1965 favus was highly epidemic and Trichophyton schoenleinii presented as the overwhelming aetiological agents of scalp infection in the study area, with a prevalence of 3...
May 2015: Mycoses
https://www.readbyqxmd.com/read/25583289/generalized-favus-the-story-of-a-legendary-case-of-tinea-favosa
#11
L Conde-Salazar Gómez, F Heras Mendaza
From the moment the Olavide Museum opened its doors in 1882 until its content was packed up around 1965 and lost sight of for a time, it underwent a succession of changes. Some of those changes cannot be fully documented now because the archives of the Provincial Council (Diputación) of Madrid were lost during the Spanish Civil War. The museum was initially housed in Hospital de San Juan de Dios, in the neighborhood of Atocha. Because this hospital treated mainly venereal diseases, much of the information we have about it comes from newspapers or magazines of the period, and their accounts were often sensationalistic...
June 2015: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/25215288/the-presence-of-biomarker-enzymes-of-selected-scleractinian-corals-of-palk-bay-southeast-coast-of-india
#12
R Anithajothi, K Duraikannu, G Umagowsalya, C M Ramakritinan
The health and existence of coral reefs are in danger by an increasing range of environmental and anthropogenic impacts. The causes of coral reef decline include worldwide climate change, shoreline development, habitat destruction, pollution, sedimentation and overexploitation. These disasters have contributed to an estimated loss of 27% of the reefs. If the current pressure continues unabated, the estimated loss of coral reef will be about 60% by the year 2030. Therefore, the present study was aimed to analyze the enzymes involved in stress induced by coral pathogen and its resistance...
2014: BioMed Research International
https://www.readbyqxmd.com/read/24864605/clinical-types-of-tinea-capitis-and-species-identification-in-children-an-experience-from-tertiary-care-centres-of-karachi-pakistan
#13
Maria Farooqi, Saadia Tabassum, Dilawar Abbas Rizvi, Atiya Rahman, Rehanuddin, Safia Awan, Sikandar Azam Mahar
OBJECTIVE: To study the clinical types of Tinea Capitis and identify species in children reporting to two tertiary care centres of Karachi, Pakistan. METHODS: The descriptive, cross-sectional study was conducted at the Dermatology Outpatients' Department, PNS Shifa Hospital and the Institute of Skin Diseases, Karachi, from January 1, 2008 to December 31, 2009. It comprised 202 children with clinical diagnosis of tinea capitis, confirmed by skin scrapings, showing fungal hyphae and spores in 10% potassium hydroxide on direct microscopy...
March 2014: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/24746723/-epidemiology-of-tinea-capitis-in-the-suburbs-of-tipasa-algeria
#14
A Bendjaballah-Laliam, H Djazer
UNLABELLED: Tinea capitis represent a public health problem in Algeria, despite improvement of living conditions. We conducted a retrospective study of cases diagnosed in the hospital Hadjout (Tipasa), Algeria, during 3 years (January 2010-January 2013). RESULT: Among a total of 213 hair samples, 133 were positive (direct examination or culture). Incidence average was 44 cases per year. Patients were under 12 years of age in 91%. Three species of dermatophytes were isolated: Trichophyton violaceum (66%), Microsporum canis (32...
June 2014: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/24625676/cat-favus-caused-by-microsporum-incurvatum-comb-nov-the-clinical-and-histopathological-features-and-molecular-phylogeny
#15
Pei-Lun Sun, Chao-An Mu, Chi-Chen Fan, Yun-Chen Fan, Jer-Ming Hu, Yu-Ming Ju
Favus is a distinctive form of infection that is caused by exclusively dermatophytes. Its clinical presentation is characterized by scutula, which are concave, thick fungal crusts. The best-known examples of human scalp favus are caused by Trichophyton schoenleinii and those of mouse favus are caused by T. quinckeanum. However, other dermatophytes, such as T. violaceum, T. verrucosum, Microsporum audouinii, M. gallinae, M. gypseum, and M. canis, have been reported sporadically to cause favic lesions. Favus on cats has rarely been mentioned in the literature, and the pathogens with which it has been associated are, for the most part, unknown...
April 2014: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/24577348/the-clinical-diagnosis-of-osteoporosis-a-position-statement-from-the-national-bone-health-alliance-working-group
#16
E S Siris, R Adler, J Bilezikian, M Bolognese, B Dawson-Hughes, M J Favus, S T Harris, S M Jan de Beur, S Khosla, N E Lane, R Lindsay, A D Nana, E S Orwoll, K Saag, S Silverman, N B Watts
UNLABELLED: Osteoporosis causes an elevated fracture risk. We propose the continued use of T-scores as one means for diagnosis but recommend that, alternatively, hip fracture; osteopenia-associated vertebral, proximal humerus, pelvis, or some wrist fractures; or FRAX scores with ≥3% (hip) or 20% (major) 10-year fracture risk also confer an osteoporosis diagnosis. INTRODUCTION: Osteoporosis is a common disorder of reduced bone strength that predisposes to an increased risk for fractures in older individuals...
May 2014: Osteoporosis International
https://www.readbyqxmd.com/read/24572157/osteoporosis-and-the-aging-athlete
#17
M J Favus
Osteoporosis is a clinical syndrome of bone fragility resulting in fractures with minimal or no trauma. Bone strength is directly related to bone mass, therefore factors that influence bone mass will determine the subsequent risk of osteoporotic fracture. Estrogen loss at the menopause is the most common cause of osteoporosis. Factors that limit the process of bone formation during adolescence and early adulthood can interfere with reaching peak adult bone mass and thereby predispose to osteoporosis in later adult years...
January 1, 1995: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/24432210/tinea-capitis-favosa-misdiagnosed-as-tinea-amiantacea
#18
Sonia Anane, Olfa Chtourou
INTRODUCTION: Favus of the scalp or tinea capitis favosa is a chronic dermatophyte infection of the scalp. In almost cases, favus is caused by Trichophyton schoenleinii, anthropophilic dermatophyte. It is characterized by the presence of scutula and severe alopecia. Besides the classic clinical type of tinea capitis favosa, there are many variant of clinical form which may persist undiagnosed for many years. In this work, we report an atypical form of favus to Trichophyton schoenleinii which was misdiagnosed as tinea amiantacea...
December 28, 2012: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/24312990/robert-remak-1815-1865-discoverer-of-the-fungal-character-of-dermatophytoses
#19
Andrzej Grzybowski, Krzysztof Pietrzak
Robert Remak was the first scientist to undertake successful research on fungal skin infections. A neurologist, physiologist, and embryologist, Remak was the first to observe the fungal changes causing the disease of favus; however, he gave credit for the discovery to Professor Johann Schönlein and denied all attempts by others to credit him with the discovery by calling them a mistake. He named the disease Achorion schönleinii; however, over time, the name was changed to Trichophyton schoenleinii. Remak also described axial fibers encased in a medullary sheath and was the first to recognize nonmyelated (sympathetic) nerve fibers, today called fibers of Remak...
November 2013: Clinics in Dermatology
https://www.readbyqxmd.com/read/24082227/favus-in-an-elderly-kashmiri-female-a-rare-occurrence
#20
Iffat Hassan, Parvaiz A Rather, Peerzada Sajad
No abstract text is available yet for this article.
September 2013: Indian Journal of Dermatology
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