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https://www.readbyqxmd.com/read/29342061/the-effect-of-alternative-bearing-surfaces-on-the-risk-of-revision-due-to-infection-in-minimally-stabilized-total-knee-replacement-an-analysis-of-326-603-prostheses-from-the-australian-orthopaedic-association-national-joint-replacement-registry
#1
Christopher J Vertullo, Peter L Lewis, Yi Peng, Stephen E Graves, Richard N de Steiger
BACKGROUND: The effect of alternative bearing materials on the risk of revision due to infection after total knee replacement remains uncertain. By reducing the immunomodulating polyethylene wear-particle burden and with different substrate bacterial adhesion properties, Oxinium oxidized zirconium and cross-linked polyethylene (XLPE) could alter infection risk. The purpose of the current study was to analyze the risk of revision for infection in 3 comparisons of bearing combinations. METHODS: To evaluate the risk of revision for infection with XLPE, cobalt-chromium (CoCr) on XLPE was compared with CoCr on non-cross-linked polyethylene (NXLPE)...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29339190/systemic-and-local-toxicity-of-metal-particles-released-from-hip-prostheses-a-review-of-experimental-approaches
#2
REVIEW
Divya Rani Bijukumar, Abhijith Segu, Júlio Cesar Matias de Souza, XueJun Li, Mark Barba, Louis Mercuri, Joshua Jacobs, Mathew Thoppil Mathew
Despite the technological improvements in orthopedic joint replacement implants, wear and corrosion products associated with the metal components of these implants may result in adverse local tissue and perhaps systemic reactions and toxicities. The current review encompasses a literature review of the local and systemic toxicity studies concerning the effect of CoCrMo wear particles released from wear and corrosion of orthopedic implants and prostheses. Release of metallic debris is mainly in the form of micro- and nano-particles, ions of different valences, and oxides composed of Co and Cr...
January 12, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29338713/lncrna-dancr-involved-osteolysis-after-total-hip-arthroplasty-by-regulating-foxo1-expression-to-inhibit-osteoblast-differentiation
#3
Zhenyu Tang, Zongming Gong, Xiaoliang Sun
BACKGROUND: Aseptic loosening of artificial hip joint is a major complication affecting the long-term use of the artificial hip joint, and is the main cause of joint replacement failure. However, the mechanism of aseptic loosening of THR has not yet cleared. The aim of this study was to investigate the underlying mechanism of DANCR in osteoblast differentiation (OD). METHODS: We detected the expressions of DANCR and FOXO1 in clinical samples and mesenchymal stem cells (MSCs) by qRT-PCR and western blotting...
January 16, 2018: Journal of Biomedical Science
https://www.readbyqxmd.com/read/29338705/frailty-as-a-predictor-of-hospital-length-of-stay-after-elective-total-joint-replacements-in-elderly-patients
#4
Han Ting Wang, Josée Fafard, Stéphane Ahern, Pascal-André Vendittoli, Paul Hebert
BACKGROUND: Total joint replacement procedures are increasing in number because of population aging and osteoarthritis development. Defined as a lack of physiological reserves and the inability to adequately respond to external stressors, frailty may be more common than expected in older patients with degenerative arthritis awaiting total joint replacements. The aim of the present study was to assess associations between frailty and adverse outcomes, frailty prevalence among elderly patients awaiting elective TJR, and agreement between 2 frailty screening instruments...
January 16, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29335931/-indications-for-joint-replacement-knee-arthroplasty
#5
S F Fucentese, C Janig
Current demographic trends with an increasing number of older patients, have led to a rising number of patients with higher demands on performance. Osteoarthritis in younger patients caused by abnormal forms or accidents also pose new challenges for medical professionals in the orthopedic field. As a rule of thumb, all conservative therapeutic possibilities should be exhausted before starting a surgical intervention. The main aims of surgery are to reduce pain, increase mobility and quality of life. In order to qualify for total knee arthroplasty (TKA) patients must fulfil major and minor criteria; however, after TKA approximately one fifth of patients are not satisfied with the result...
January 15, 2018: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29325717/factors-related-to-older-patients-fear-of-falling-during-the-first-mobilization-after-total-knee-replacement-and-total-hip-replacement
#6
Hale Turhan Damar, Ozlem Bilik, Ozgul Karayurt, Figen Erol Ursavas
The aim of this study was to determine fear of falling in the first mobilization and affecting factors in older patients. The study had a descriptive and cross-sectional design. Data were collected in Izmir, Turkey between February 2014 and March 2016. The sample included 204 older patients undergoing joint replacement surgery. Fifty-seven-point four percent and 42.6% of the patients had total hip and knee replacement respectively. 42.2% of the patients had a severe fear of falling when they were first mobilized...
January 8, 2018: Geriatric Nursing
https://www.readbyqxmd.com/read/29318944/prevalence-of-iron-deficiency-in-a-total-joint-surgery-population
#7
Jonathan H Waters, Peter Johnson, Mark H Yazer
BACKGROUND: Iron deficiency without anemia has been associated with decreases in functional work capacity and fatigue. The aim of this study was to determine the prevalence of iron deficiency without anemia in a preoperative cohort of orthopedic patients and to determine if iron deficiency is a condition which warrants inclusion into a prehabilitation program prior to surgery. METHODS: One hundred consecutive patients going through preoperative testing for total joint replacement were enrolled in the study...
January 10, 2018: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/29318943/torsional-friction-behavior-of-the-contact-interface-between-the-materials-of-an-artificial-knee-joint-replacement
#8
Handong Xu, Kai Chen, Dekun Zhang, Xuehui Yang
The torsional friction behavior of the materials (CoCrMo alloy and ultra-high-molecular-weight polyethylene (UHMWPE)) that are used in artificial knee joint replacement (AKJR) were investigated under dynamic loading. The torsional friction torque, wear loss and scars and stress distribution were analyzed and compared. The results show the following: (1) the friction torque declines rapidly at the beginning of the experiments, and meanwhile, the maximum normal load and the torsional angle amplitude show very little effect on the steady value; (2) the wear loss decreases with the increased torsional angle amplitude but increases with the increased maximum normal load; additionally, as the cycle times increase, the wear rate decreases, and the wear is minimal; (3) unloading and secondary loading significantly reduce the friction and wear of the materials, and thus, patients should rest after prolonged exercise to reduce wear; (4) the margins of UHMWPE and CoCrMo are worn, and the wear mechanism is abrasive wear; (5) around the center of the UHMWPE, the surface is peeled off, and the wear mechanism is fatigue wear; and (6) in terms of the compressive stress and shear stress, the calculated results from a finite element model match the experimental results well...
January 10, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29318860/-effect-of-transcutaneous-acupoint-electrical-stimulation-on-hemodynamic-fluctuation-caused-by-loosing-tourniquet-in-elderly-patients-undergoing-knee-joint-replacement
#9
Han-Sheng Liang, Yi Feng
OBJECTIVE: To observe the effect of transcutaneous acupoint electrical stimulation (TAES) on hemodynamic fluctuation caused by loosing tourniquet in the elderly patients undergoing knee joint replacement. METHODS: A total of 60 ASA (America Society Anesthesiologist) I or II elderly patients for elective knee joint replacement surgery were randomly divided into control group (30 cases) and TAES group (30 cases). Patients of both groups were treated by intravenous anesthesia, and monitored with bispectral index (BIS, between 45-60) for anesthesia depth, stroke volume variation (SVV) for fluid management, mean arterial pressure (MAP) and cardiac index (CI) for hemodynamic fluctuation evaluation, and with analgesia nociception index (ANI, between 50-70) for remifentanil dosage adjustment...
December 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29317922/hospital-consumer-assessment-of-healthcare-providers-and-systems-scores-relating-to-pain-following-the-incorporation-of-clinical-pharmacists-into-patient-education-prior-to-joint-replacement-surgery
#10
Erik Hefti, Michael Remington, Charles Lavallee
Background: Pharmacist involvement has been shown to improve various aspects of patient care. Patients undergoing knee and hip replacement surgery generally experience post-operative pain and discomfort. Pain control can impact patient satisfaction, as reported by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. Objective: The current pilot study aims to measure the potential impact that incorporating pharmacists into preoperative patient education programs has on the response to select HCAHPS questions...
October 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/29316598/s-orthopaedic-department-teaching-status-associated-with-adverse-outcomes-of-primary-total-knee-arthroplasty
#11
Dean C Perfetti, Nipun Sodhi, Anton Khlopas, Assem A Sultan, Suela Lamaj, Mathew R Boylan, Jared M Newman, Qais Naziri, William A Cantrell, Aditya V Maheshwari, Carl B Paulino, Michael A Mont
INTRODUCTION: Although resident physicians have a critical role in the daily management of patients, based on their limited experiences, they are thought to potentially create inefficiencies in the hospital. With changes set forth by the Comprehensive Care for Joint Replacement (CJR) program, both teaching and non-teaching hospitals are directly compared on efficiency and outcomes. Therefore, the purpose of this study was to compare outcomes between teaching and non-teaching hospitals in the state of New York...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29314768/medium-and-long-chain-acylcarnitines-are-associated-with-osteoarthritis-severity-and-arterial-stiffness-in-end-stage-osteoarthritis-patients-a-case-control-study
#12
Kaspar Tootsi, Jaak Kals, Mihkel Zilmer, Kaido Paapstel, Aigar Ottas, Aare Märtson
AIM: Arterial pathology has been suggested to be involved in osteoarthritis (OA). Metabolic profiling enables the determination of low-molecular-weight molecules, which might further explain the pathogenesis of OA and its relationship with cardiovascular diseases (CVD). The aim of this study was to compare the metabolic profile of lipid metabolism-related compounds and arterial stiffness in OA patients and in controls. METHOD: The serum of 70 end-stage OA patients prior to joint replacement surgery and 82 age-matched controls were analyzed by the AbsoluteIDQ™ p180 kit (BIOCRATES Life Sciences AG, Innsbruck, Austria) using the targeted metabolomic approach...
January 4, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29305049/muscle-activity-during-maximal-isometric-forearm-rotation-using-a-power-grip
#13
Joseph Bader, Michael R Boland, Desney Greybe, Arthur Nitz, Timothy Uhl, David Pienkowski
This study aimed to provide quantitative activation data for muscles of the forearm during pronation and supination while using a power grip. Electromyographic data was collected from 15 forearm muscles in 11 subjects while they performed maximal isometric pronating and supinating efforts in nine positions of forearm rotation. Biceps brachii was the only muscle with substantial activation in only one effort direction. It was significantly more active when supinating (µ = 52.1%, SD = 17.5%) than pronating (µ = 5...
December 15, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29304328/use-of-intraoperative-computed-tomography-in-craniomaxillofacial-trauma-surgery
#14
Karl Cuddy, Baber Khatib, R Bryan Bell, Allen Cheng, Ashish Patel, Melissa Amundson, Eric J Dierks
PURPOSE: The use of technology to aid in assessment, planning, and management of complex craniomaxillofacial injuries is increasingly common. Preoperative computed tomography (CT) evaluation is considered the standard of care, and intraoperative imaging is becoming increasingly accessible. Limited data exist regarding the implication of intraoperative CT on decision making in the management of all sites of facial fractures. The purposes of this study were to characterize the use of an intraoperative CT scanner for craniomaxillofacial surgery within our institution, to quantify the effect of intraoperative CT on surgical decision making, and to attempt to provide guidance on when to use this technology...
December 13, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29295772/differences-in-post-operative-outcome-between-conversion-and-primary-total-hip-arthroplasty
#15
Charles D Qin, Mia M Helfrich, David W Fitz, Mark A Oyer, Kevin D Hardt, David W Manning
BACKGROUND: The demand for conversion of prior hip surgery to total hip arthroplasty (conversion THA) is likely to increase as a function of increasing US hip fracture burden in addition to its application in managing other conditions. Thus, outcome analysis is warranted to better inform value-based reimbursement schemes in the era of bundled payments. METHODS: Via Current Procedural Terminology codes, the National Surgical Quality Improvement Project data files were queried for all patients who underwent primary THA and conversion of previous hip surgery to THA from 2005 to 2014...
November 29, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29291157/staphylococcus-epidermidis-isolates-from-nares-and-prosthetic-joint-infections-are-mupirocin-susceptible
#16
Lavin Salih, Staffan Tevell, Emeli Månsson, Åsa Nilsdotter-Augustinsson, Bengt Hellmark, Bo Söderquist
The objective of the present study was to investigate the antibiotic susceptibility including mupirocin among Staphylococcus. epidermidis isolated from prosthetic joint infections (PJIs) (n=183) and nasal isolates (n=75) from patients intended to undergo prosthetic joint replacements. Susceptibility to mupirocin (used for eradication of nasal carriership of Staphylococcus aureus) was investigated by gradient test, and susceptibility to various other antimicrobial agents was investigated by disc diffusion test...
2018: Journal of Bone and Joint Infection
https://www.readbyqxmd.com/read/29290333/technology-assisted-hip-and-knee-arthroplasties-an-analysis-of-utilization-trends
#17
Matthew Boylan, Kelly Suchman, Jonathan Vigdorchik, James Slover, Joseph Bosco
BACKGROUND: Robotic and computer navigation technology is available to surgeons for use in hip and knee arthroplasties to increase the precision of component placement. However, they do add significant costs to these procedures, and the long-term clinical outcomes and value of technology assistance for joint replacement remain unclear. METHODS: We identified 321,522 patients in Medicare Severity Diagnosis Related Groups 469 and 470 who underwent primary total hip arthroplasty (N = 133,472) or primary total or unicompartmental knee arthroplasty (N = 188,050) between 2008 and 2015 in the New York Statewide Planning and Research Cooperative System (SPARCS)...
November 29, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29289415/insights-from-the-design-and-implementation-of-a-single-entry-model-of-referral-for-total-joint-replacement-surgery-critical-success-factors-and-unanticipated-consequences
#18
Zaheed Damani, Gail MacKean, Eric Bohm, Tom Noseworthy, Jenney Meng Han Wang, Brie DeMone, Brock Wright, Deborah A Marshall
BACKGROUND: Single-entry models (SEMs) in healthcare allow patients to see the next-available provider and have been shown to improve waiting times, access and patient flow for preference-sensitive, scheduled services. The Winnipeg Central Intake Service (WCIS) for hip and knee replacement surgery was implemented to improve access in the Winnipeg Regional Health Authority. This paper describes the system's design/implementation; successes, challenges, and unanticipated consequences. METHODS: On two occasions, during and following implementation, we interviewed all members of the WCIS project team, including processing engineers, waiting list coordinators, administrators and policy-makers regarding their experiences...
November 4, 2017: Health Policy
https://www.readbyqxmd.com/read/29288807/major-inpatient-surgeries-and-in-hospital-mortality-in-new-south-wales-public-hospitals-in-australia-a-state-wide-retrospective-cohort-study
#19
Wei Du, Nicholas Glasgow, Paul Smith, Archie Clements, Art Sedrakyan
BACKGROUND: Surgical interventions save lives and are important focus for health services research worldwide. Investigating variation in postoperative mortality may improve understanding of unwarranted variations and promote safety and quality in surgical care. We aimed to evaluate trends of in-hospital mortality rates among adult inpatients receiving major elective surgeries and determine the variation in mortality among New South Wales (NSW) public hospitals. MATERIALS AND METHODS: In this study, we used the all-inclusive population-based NSW Admitted Patient Data from July 2001 to June 2014...
December 27, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29284048/the-mediating-effect-of-body-mass-index-on-the-relationship-between-smoking-and-hip-or-knee-replacement-due-to-primary-osteoarthritis-a-population-based-cohort-study-the-hunt-study
#20
Marianne Bakke Johnsen, Alf Inge Hellevik, Milada Cvancarova Småstuen, Arnulf Langhammer, Ove Furnes, Gunnar Birkeland Flugsrud, Lars Nordsletten, John Anker Zwart, Kjersti Storheim
To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the Nord-Trøndelag Health Study (the HUNT Study) were linked to the Norwegian Arthroplasty Register to detect the first THR or TKR due to primary OA. A mediation analysis was used to decompose the total effect of smoking into a direct and indirect effect. BMI was considered a mediator in the analysis...
2017: PloS One
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