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https://www.readbyqxmd.com/read/29141380/-the-analysis-of-anesthetic-management-for-renal-cell-carcinoma-with-associated-inferior-vena-cava-tumor-thrombus
#1
H Zeng, X Y Rong, Y Wang, X Y Guo
Objective: To explore the key points of anesthetic management for renal cell carcinoma combined with inferior vena cava (IVC) tumor thrombus. Methods: Twenty-seven cases of renal cell carcinoma with inferior vena cava (IVC) tumor thrombus underwent radical nephrectomy and inferior caval venous thrombectomy were reviewed retrospectively during January 2014 to January 2017 in our hospital.Analyzed data includs demographics, classification of tumor, perioperative anesthetic management and monitoring approaches, IVC clamping time , vital signs during cardiopulmonary bypass(CPB), estimated blood loss (EBL), usage of blood products, hospitalization time and ICU time , as well as postoperative outcomes...
November 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29140977/low-cost-and-open-source-multi-fluorescence-imaging-system-for-teaching-and-research-in-biology-and-bioengineering
#2
Isaac Nuñez, Tamara Matute, Roberto Herrera, Juan Keymer, Timothy Marzullo, Timothy Rudge, Fernán Federici
The advent of easy-to-use open source microcontrollers, off-the-shelf electronics and customizable manufacturing technologies has facilitated the development of inexpensive scientific devices and laboratory equipment. In this study, we describe an imaging system that integrates low-cost and open-source hardware, software and genetic resources. The multi-fluorescence imaging system consists of readily available 470 nm LEDs, a Raspberry Pi camera and a set of filters made with low cost acrylics. This device allows imaging in scales ranging from single colonies to entire plates...
2017: PloS One
https://www.readbyqxmd.com/read/29140950/development-of-clinical-process-measures-for-pediatric-burn-care-understanding-variation-in-practice-patterns
#3
Lewis E Kazis, Robert L Sheridan, Gabriel D Shapiro, Austin F Lee, Matthew H Liang, Colleen M Ryan, Jeffrey C Schneider, Martha Lydon, Marina Soley-Bori, Lily A Sonis, Emily C Dore, Tina Palmieri, David Herndon, Walter Meyer, Petra Warner, Richard Kagan, Frederick J Stoddard, Michael Murphy, Ronald G Tompkins
BACKGROUND: There has been little systematic examination of variation in pediatric burn care clinical practices and its effect on outcomes. As a first step, current clinical care processes need to be operationally defined. The highly specialized burn care units of the Shriners Hospitals for Children system present an opportunity to describe the processes of care. The aim of this study was to develop a set of process-based measures for pediatric burn care and examine adherence to them by providers in a cohort of pediatric burn patients...
November 14, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29140681/orthogonal-operation-of-constitutional-dynamic-networks-consisting-of-dna-tweezer-machines
#4
Liang Yue, Shan Wang, Alessandro Cecconello, Jean-Marie Lehn, Itamar Willner
Overexpression or down-regulation of cellular processes are often controlled by dynamic chemical networks. Bioinspired by nature, we introduce constitutional dynamic networks (CDNs) as systems that emulate principle of the nature processes. The CDNs comprise of dynamically exchangeable equilibrated constituents that respond to external triggers by adapting the composition of the dynamic mixture to the energetic stabilization of the constituents. We introduce a nucleic acid-based CDN that includes four exchangeable and mechanically-triggered tweezers AA', BB', AB' and BA' existing in close, close, open and open configurations, respectively...
November 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/29140639/determining-the-effectiveness-of-mirrors-and-camera-systems-in-monitoring-the-rearward-visibility-of-self-propelled-agricultural-machinery
#5
Shawn G Ehlers, William E Field
This study concerned the ability of operators of tractors and other self-propelled agricultural machinery to visually recognize objects and/or hazards within close proximity to the rear of those machines and/or any implements in tow, especially when backing up. It was hypothesized that the data collected would identify the factors affecting rearward visibility and help determine the effectiveness of two backup-assisting devices (i.e., mirrors and camera systems) in enhancing the operator's ability to observe objects or hazards...
July 31, 2017: Journal of Agricultural Safety and Health
https://www.readbyqxmd.com/read/29140617/methods-of-collecting-and-analyzing-rearward-visibility-data-for-agricultural-machinery-hazard-and-or-object-detectability
#6
Shawn G Ehlers, William E Field, Daniel R Ess
Recent interest in rearward visibility for private, construction, and commercial vehicles and documentation of rearward runovers involving bystanders outside the field of vision of the vehicle operator led to an investigation into the need for enhanced methods of rearward visibility for large, off-highway, agricultural equipment. A review of the literature found limited relevant research and minimal data on incidents involving rearward runovers of bystanders and co-workers. This article reviews the findings regarding the methods identified and tested to collect and analyze rearward visibility data, from the operator's perspective, for large self-propelled agricultural equipment, including the four-wheel drive tractors, combines, agricultural sprayers, and skid-steer loaders that are increasingly found on agricultural production sites...
January 26, 2017: Journal of Agricultural Safety and Health
https://www.readbyqxmd.com/read/29140605/highly-transparent-and-integrable-surface-texture-change-device-for-localized-tactile-feedback
#7
Ankit, Naveen Tiwari, Mayank Rajput, Nguyen Anh Chien, Nripan Mathews
Human-machine haptic interaction is typically detected by variations in friction, roughness, hardness, and temperature, which combines to create sensation of surface texture change. Most of the current technologies work to simulate changes in tactile perception (via electrostatic, lateral force fields, vibration motors, etc.) without creating actual topographical transformations. This makes it challenging to provide localized feedback. Here, a new concept for on-demand surface texture augmentation that is capable of physically forming local topographic features in any predesigned pattern is demonstrated...
November 15, 2017: Small
https://www.readbyqxmd.com/read/29140539/cross-regulation-among-arabinose-xylose-and-rhamnose-utilization-systems-in-e-coli
#8
Debika Choudhury, Supreet Saini
Bacteria frequently encounter multiple sugars in their natural surroundings. While the dynamics of utilization of glucose containing sugar mixtures have been well investigated, there are few reports addressing regulation of utilization of glucose-free mixtures particularly pentoses. These sugars comprise a considerable fraction in hemicellulose which can be converted by suitable biocatalysts to biofuels and other value-added products. Hence understanding of transcriptional cross-regulation among different pentose sugar utilization systems is essential for successful development of industrial strains...
November 15, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/29140470/database-resources-of-the-national-center-for-biotechnology-information
#9
(no author information available yet)
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. The Entrez system provides search and retrieval operations for most of these data from 39 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets...
November 13, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29140373/clinical-considerations-of-adapted-drilling-protocol-by-bone-quality-perception
#10
Marco Toia, Michele Stocchero, Francesca Cecchinato, Enrico Corrà, Ryo Jimbo, Denis Cecchinato
PURPOSE: To evaluate insertion torque value (ITV) and marginal bone loss (MBL) of an implant system after a clinically perceived bone quality-adapted drilling. MATERIALS AND METHODS: This multicenter retrospective study included patients treated with implants, conventionally loaded, in completely healed sites. Operators customized the osteotomy preparation according to radiographic assessment and their perception of bone quality. Drilling sequence, bone quality, and ITV were recorded at the time of surgery...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29140362/coupling-in-a-dual-metallo-dielectric-nanolaser-system
#11
Suruj S Deka, Si Hui Pan, Qing Gu, Yeshaiahu Fainman, Abdelkrim El Amili
To achieve high packing density in on-chip photonic integrated circuits, subwavelength scale nanolasers that can operate without crosstalk are essential components. Metallo-dielectric nanolasers are especially suited for this type of dense integration due to their lower Joule loss and nanoscale dimensions. Although coupling between optical cavities when placed in proximity to one another has been widely reported, whether the phenomenon is induced for metal-clad cavities has not been investigated thus far. We demonstrate coupling between two metallo-dielectric nanolasers by reducing the separation between the two cavities...
November 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29140329/demonstration-of-a-cw-diode-pumped-ar-metastable-laser-operating-at-4%C3%A2-%C3%A2-w
#12
J Han, M C Heaven, P J Moran, G A Pitz, E M Guild, C R Sanderson, B Hokr
Optically pumped rare gas lasers are being investigated as potential high-energy, high beam quality systems. The lasing medium consists of rare gas atoms (Rg=Ne, Ar, Kr, or Xe) that have been electric discharge excited to the metastable np(5)(n+1)s P32 state. Following optical excitation, helium (He) at pressures of 200-1000 Torr is used as the energy transfer agent to create a population inversion. The primary technical difficulty for this scheme is the discharge production of sufficient Rg* metastables in the presence of >200  Torr of He...
November 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29140282/magnetic-material-assessment-of-a-novel-ultra-high-step-up-converter-with-single-semiconductor-switch-and-galvanic-isolation-for-fuel-cell-power-system
#13
Chih-Lung Shen, Heng Liou
In this paper, a novel step-up converter is proposed, which has the particular features of single semiconductor switch, ultra-high conversion ratio, galvanic isolation, and easy control. Therefore, the proposed converter is suitable for the applications of fuel-cell power system. Coupled inductors and switched capacitors are incorporated in the converter to obtain an ultra-high voltage ratio that is much higher than that of a conventional high step-up converter. Even if the turns ratio of coupled inductor and duty ratio are only to be 1 and 0...
November 15, 2017: Materials
https://www.readbyqxmd.com/read/29139077/spatiotemporal-patterns-and-source-attribution-of-nitrogen-pollution-in-a-typical-headwater-agricultural-watershed-in-southeastern-china
#14
Wenjun Chen, Bin He, Daniel Nover, Weili Duan, Chuan Luo, Kaiyan Zhao, Wen Chen
Excessive nitrogen (N) discharge from agriculture causes widespread problems in aquatic ecosystems. Knowledge of spatiotemporal patterns and source attribution of N pollution is critical for nutrient management programs but is poorly studied in headwaters with various small water bodies and mini-point pollution sources. Taking a typical small watershed in the low mountains of Southeastern China as an example, N pollution and source attribution were studied for a multipond system around a village using the Hydrological Simulation Program-Fortran (HSPF) model...
November 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29139057/cadaveric-simulation-a-review-of-reviews
#15
REVIEW
M Yiasemidou, E Gkaragkani, D Glassman, C S Biyani
BACKGROUND: Traditional surgical training, largely based on the Halstedian model "see one, do one, teach one" is not as effective in the era of working time restrictions and elaborate shift-patterns. As a result, contemporary surgeons turned to educational methods outside the operating theatre such as simulation. Cadavers are high fidelity models but their use has ethical and cost implications and their availability may be limited. In this review, we explore the role of cadaveric simulation in modern surgical education...
November 14, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29138544/early-postoperative-delirium-after-hemiarthroplasty-in-elderly-patients-aged-over-70-years-with-displaced-femoral-neck-fracture
#16
Yi-Hwa Choi, Dae-Hwan Kim, Tae-Young Kim, Tae-Wan Lim, Seok-Woo Kim, Je-Hyun Yoo
Purpose: Postoperative delirium is a risk factor for worse outcome after hip fracture surgery in elderly patients. Postoperative delirium is associated with anesthesia, postoperative pain, and patient factors. We investigated the incidence, predictors, and prognostic implications of post-operative delirium after hemiarthroplasty (HA) in elderly patients with femoral neck fracture. Patients and methods: A total of 356 consecutive patients aged >70 years who underwent HA for femoral neck fracture were enrolled...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29138307/microdiversity-of-an-abundant-terrestrial-bacterium-encompasses-extensive-variation-in-ecologically-relevant-traits
#17
Alexander B Chase, Ulas Karaoz, Eoin L Brodie, Zulema Gomez-Lunar, Adam C Martiny, Jennifer B H Martiny
Much genetic diversity within a bacterial community is likely obscured by microdiversity within operational taxonomic units (OTUs) defined by 16S rRNA gene sequences. However, it is unclear how variation within this microdiversity influences ecologically relevant traits. Here, we employ a multifaceted approach to investigate microdiversity within the dominant leaf litter bacterium, Curtobacterium, which comprises 7.8% of the bacterial community at a grassland site undergoing global change manipulations. We use cultured bacterial isolates to interpret metagenomic data, collected in situ over 2 years, together with lab-based physiological assays to determine the extent of trait variation within this abundant OTU...
November 14, 2017: MBio
https://www.readbyqxmd.com/read/29137847/comparison-between-radiological-semantic-features-and-lung-rads-in-predicting-malignancy-of-screen-detected-lung-nodules-in-the-national-lung-screening-trial
#18
Qian Li, Yoganand Balagurunathan, Ying Liu, Jin Qi, Matthew B Schabath, Zhaoxiang Ye, Robert J Gillies
RATIONALE: Lung computed tomography (CT) Screening Reporting and Data System (lung-RADS) has standardized follow-up and management decisions in lung cancer screening. To date, little is known how lung-RADS classification compares with radiological semantic features in risk prediction and diagnostic discrimination. OBJECTIVES: To compare the performance of radiological semantic features and lung-RADS in predicting nodule malignancy in lung cancer screening. METHODS: We used data and low-dose CT (LDCT) images from the National Lung Screening Trial (NLST)...
October 13, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/29137795/cerium-substituted-magnetite-fabrication-characterization-and-sonocatalytic-activity-assessment
#19
Alireza Khataee, Ramin Hassandoost, Shima Rahim Pouran
The present paper reports the sonocatalytic activity of cerium-substituted-magnetite for removal of oxytetracycline (OTC). The catalyst was prepared through a chemical route (co-precipitation, Fe3-xCexO4) and a mechanical procedure (CeO2/Fe3O4). Subsequently, the physico-chemical characteristics of both samples were determined using XRD, BET, SEM, EDX, TEM, Dot-mapping, FT-IR, DRS, and VSM analysis and compared to pristine magnetite and ceria. Afterwards, the effects of various operational conditions were assessed on sonocatalytic performance of Fe2...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29137365/longitudinal-serum-metabolomics-evaluation-of-trastuzumab-and-everolimus-combination-as-pre-operative-treatment-for-her-2-positive-breast-cancer-patients
#20
Elodie Jobard, Olivier Trédan, Thomas Bachelot, Arnaud M Vigneron, Céline Mahier Aït-Oukhatar, Monica Arnedos, Maria Rios, Jacques Bonneterre, Véronique Diéras, Marta Jimenez, Jean-Louis Merlin, Mario Campone, Bénédicte Elena-Herrmann
The mammalian target of rapamycin complex 1 (mTORC1) is an attractive target for HER-2 positive breast cancer therapy because of its key role in protein translation regulation, cell growth and metabolism. We present here a metabolomic investigation exploring the impact of mTOR inhibition on serum metabolic profiles from patients with non-metastatic breast cancer overexpressing HER-2. Baseline, treatment-related and post-treatment serum samples were analyzed for 79 patients participating in the French clinical trial RADHER, in which randomized patients with HER-2 positive breast cancer received either trastuzumab alone (arm T) or a trastuzumab and everolimus combination (arm T+E)...
October 13, 2017: Oncotarget
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