Alexandra Lebedeva, Olesya Kuznetsova, Maxim Ivanov, Alexandra Kavun, Egor Veselovsky, Ekaterina Belova, Vladislav Mileyko, Valentina Yakushina, Polina Shilo, Alexey Tryakin, Alexey Rumyantsev, Fedor Moiseenko, Mikhail Fedyanin, Dmitry Nosov
Genomic profiling, or molecular profiling of the tumor, is becoming a key component of therapeutic decision making in clinical oncology, and is typically carried out via next generation sequencing. However, the interpretation of the results and evaluation of rationale for targeting the uncovered alterations is challenging and requires a deep understanding of cancer biology, genetics, genomics and oncology. Multidisciplinary molecular tumor boards represent a promising strategy in the facilitation of molecularly-informed therapeutic decisions, and usually consist of specialists with various fields of expertise...
May 15, 2024: Heliyon