keyword
MENU ▼
Read by QxMD icon Read
search

Deep block

keyword
https://www.readbyqxmd.com/read/28213155/high-frequency-stimulation-of-afferent-fibers-generates-asynchronous-firing-in-the-downstream-neurons-in-hippocampus-through-partial-block-of-axonal-conduction
#1
Zhouyan Feng, Zhaoxiang Wang, Zheshan Guo, Wenjie Zhou, Ziyan Cai, Dominique M Durand
Deep brain stimulation (DBS) is effective for treating neurological disorders in clinic. However, the therapeutic mechanisms of high-frequency stimulation (HFS) of DBS have not yet been elucidated. Previous studies have suggested that HFS-induced changes in axon conduction could have important contributions to the DBS effects and desiderate further studies. To investigate the effects of prolonged HFS of afferent axons on the firing of downstream neurons, HFS trains of 100 and 200 Hz were applied on the Schaffer collaterals of the hippocampal CA1 region in anaesthetized rats...
February 14, 2017: Brain Research
https://www.readbyqxmd.com/read/28209746/a-phase-ii-randomized-trial-go27827-of-first-line-folfox-plus-bevacizumab-with-or-without-the-met-inhibitor-onartuzumab-in-patients-with-metastatic-colorectal-cancer
#2
Johanna C Bendell, Howard Hochster, Lowell L Hart, Irfan Firdaus, Joseph R Mace, Joshua J McFarlane, Mark Kozloff, Daniel Catenacci, Jessie J Hsu, Stephen P Hack, David S Shames, See-Chun Phan, Hartmut Koeppen, Allen L Cohn
BACKGROUND: Dysregulated hepatocyte growth factor/mesenchymal-epithelial transition (MET) signaling is associated with poor prognosis and resistance to vascular endothelial growth factor inhibition in metastatic colorectal cancer (mCRC). We report outcomes from a double-blind, multicenter phase II trial of the MET inhibitor onartuzumab in combination with mFOLFOX-6 and bevacizumab for mCRC (GO27827; NCT01418222). MATERIALS AND METHODS: Patients were randomized 1:1 to receive onartuzumab (10 mg/kg intravenously [IV]) or placebo plus mFOLFOX-6 and bevacizumab (5 mg/kg IV)...
February 16, 2017: Oncologist
https://www.readbyqxmd.com/read/28203542/robotic-trans-atrial-and-trans-mitral-ventricular-septal-resection
#3
REVIEW
W Randolph Chitwood
Localized ventricular septal hypertrophy, also known as idiopathic hypertrophic subaortic stenosis or idiopathic hypertrophic subaortic septal obstruction (IHSS), can create severe ventricular outflow obstruction. This often results in a high sub-aortic pressure gradient with potentially lethal symptoms. In 1960, Braunwald described the hemodynamic characteristics of IHSS, and thereafter, Morrow developed a trans-aortic approach to resect a large part of the ventricular septum, enlarging the outflow tract. The Morrow operation has remained the gold standard for surgically treating this pathology...
January 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28203021/-comparision-for-clinical-efficiency-of-continuous-adductor-canal-block-and-femoral-nerve-block-in-total-knee-arthroplasty
#4
M W Zhao, N Wang, L Zeng, M Li, Z K Zhao, H Zhang, H Tian
OBJECTIVE: To compare the pain control efficiency of continuous adductor canal block (ACB) and femoral nerve block (FNB) in total knee arthroplasty. METHODS: From April to September 2016, patients with severe knee osteoarthritis undergoing primary unilateral total knee arthroplasty (TKA) were prospectively observed, and all the patients were randomized received ultrasound-guided continuous ACB or FNB after surgery. Numeric pain rating scales(NPRS)pain scores in rest and activity 2, 6, 12, 24 and 48 h after surgery were collected, and the preoperative and postoperative quadriceps strength at 24 and 48 h were analyzed...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28192858/deep-and-superficial-circumflex-iliac-arteries-and-their-relationship-to-the-ultrasound-guided-femoral-nerve-block-procedure-a-cadaver-study
#5
Keiko Ogami, Hiroaki Murata, Akiko Sakai, Shuntaro Sato, Kazunobu Saiki, Keishi Okamoto, Yoshitaka Manabe, Tetsuya Hara, Toshiyuki Tsurumoto
BACKGROUND: The in-plane lateral to medial approach is a standard technique for ultrasound-guided femoral nerve block (USG-FNB). The first bifurcation of the femoral artery, which consists of the deep artery of the thigh (DAT) or occasionally the lateral circumflex femoral artery (LCFA), is regarded as the distal border for this procedure. We sometimes detect arteries along the estimated needle trajectory for USG-FNB. The superficial (SCIA) and deep (DCIA) circumflex iliac arteries run laterally parallel to the inguinal ligament from the femoral or external iliac artery...
February 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28188324/-regional-anesthesia-for-carotid-surgery-an-overview-of-anatomy-techniques-and-their-clinical-relevance
#6
A Koköfer, J Nawratil, M Opperer
BACKGROUND: Perioperative care for patients undergoing carotid endarterectomy (CEA) often presents a challenge to the anesthesia provider, as this patient group commonly suffers from a wide range of comorbidities. Although clinical trials could not demonstrate a significant benefit associated with regional anesthesia for outcomes such as insult, cardiac infarction or mortality, many authors concur that regional anesthetic techniques might be preferential in specific patient populations for this type of surgery...
February 10, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28188132/mir-28-regulates-the-germinal-center-reaction-and-blocks-tumor-growth-in-preclinical-models-of-non-hodgkin-lymphoma
#7
Nahikari Bartolomé-Izquierdo, Virginia G de Yébenes, Angel F Álvarez-Prado, Sonia M Mur, Juan A Lopez Del Olmo, Sergio Roa, Jesus Vazquez, Almudena R R Ramiro
Non-Hodgkin Lymphoma (NHL) comprises a variety of neoplasms, many of which arise from germinal center (GC)-experienced B cells. microRNA-28 (miR-28) is a GC-specific microRNA whose expression is lost in numerous mature B cell neoplasms. Here we show that miR-28 regulates the GC reaction in primary B cells by impairing CSR and memory B and plasma cell differentiation. Deep quantitative proteomics combined with transcriptome analysis identified miR-28 targets involved in cell cycle and B cell receptor signaling...
February 10, 2017: Blood
https://www.readbyqxmd.com/read/28186727/controlled-synthesis-of-ultralong-carbon-nanotubes-with-perfect-structures-and-extraordinary-properties
#8
Rufan Zhang, Yingying Zhang, Fei Wei
Carbon nanotubes (CNTs) have drawn intensive research interest in the past 25 years due to their excellent properties and wide applications. Ultralong CNTs refers to the horizontally aligned CNT arrays which are usually grown on flat substrates, parallel with each other with large intertube distances. They usually have perfect structures, excellent properties, and lengths up to centimeters, even decimeters. Ultralong CNTs are promising candidates as building blocks for transparent displays, nanoelectronics, superstrong tethers, aeronautics and aerospace materials, etc...
February 10, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28186424/defining-local-nerve-blocks-for-feline-distal-pelvic-limb-surgery-a-cadaveric-study
#9
Masataka Enomoto, B Duncan X Lascelles, Mathew P Gerard
Objectives Anatomical and methodological detail is lacking regarding local anesthetic peripheral nerve block techniques for distal pelvic limb surgery in cats. The aim of this study was to develop, describe and test nerve block methods based on cadaveric dissections and dye injections. Methods Ten pairs of feline pelvic limbs (n = 20) were dissected and the tibial nerve (T n.), common fibular (peroneal) nerve (CF n., and its two branches, the superficial fibular [peroneal] nerve [SpF n.] and the deep fibular [peroneal] nerve [DpF n...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28177212/amorphous-tin-oxide-as-low-temperature-processed-electron-transport-layer-for-organic-and-hybrid-perovskite-solar-cells
#10
Jeremy Barbe, Max L Tietze, Marios Neophytou, Banavoth Murali, Erkki Alarousu, Abdulrahman El Labban, Mutalifu Abulikemu, Wan Yue, Omar F Mohammed, Iain McCulloch, Aram Amassian, Silvano Del Gobbo
The chemical bath deposition of tin oxide (SnO2) thin films as electron transporting layer (ETL) in planar heterojunction n-i-p organohalide lead perovskite and organic bulk heterojunction solar cells is reported. The amorphous SnO2 films are grown from a non-toxic aqueous bath of tin chloride at very low temperatures (55°C) and do not require post-annealing treatment to work very effectively as ETL in planar heterojunction n-i-p organohalide lead perovskite or organic bulk heterojunction solar cells, in lieu of the commonly used ETL materials TiO2 and ZnO, respectively...
February 8, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28174737/metagenomic-characterization-of-microbial-communities-in-situ-within-the-deeper-layers-of-the-ileum-in-crohn-s-disease
#11
Chandra Sekhar Pedamallu, Ami S Bhatt, Susan Bullman, Sharyle Fowler, Samuel S Freeman, Jacqueline Durand, Joonil Jung, Fujiko Duke, Veronica Manzo, Diana Cai, Ashwin Ananthakrishnan, Akinyemi I Ojesina, Aruna Ramachandran, Dirk Gevers, Ramnik J Xavier, Atul K Bhan, Matthew Meyerson, Vijay Yajnik
BACKGROUND & AIMS: Microbial dysbiosis and aberrant host-microbe interactions in the gut are believed to contribute to the development and progression of Crohn's disease (CD). Microbiome studies in CD typically have focused on microbiota in feces or superficial mucosal layers of the colon because accessing DNA from deeper layers of the bowel is challenging. In this study, we analyzed the deep tissue microbiome in patients who underwent surgical resection of the small intestine. METHODS: Paraffin blocks were obtained from 12 CD patients undergoing ileocecal resection, and healthy ileum samples (inflammatory bowel disease-free controls) were obtained from 12 patients undergoing surgery for right-sided colon cancer...
September 2016: Cellular and Molecular Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28168695/forensic-considerations-in-cases-of-myotonic-dystrophy-at-autopsy
#12
Kimberley J Omond, Roger W Byard
Myotonic dystrophy (DM) is a chronic, slowly progressive, autosomal-dominant disorder with delayed muscle relaxation after contraction, distal skeletal muscle weakness, and atrophy. It has a reduced life expectancy due predominantly to respiratory failure or sudden cardiac death. The mortality rate is approximately 7.3 times greater than the general population with a mean age at death of 53 years. Degeneration of the cardiac conduction system causes atrioventricular block, arrhythmias, and ventricular failure...
February 7, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28161666/cellular-internalization-and-transport-of-biodegradable-polyester-dendrimers-on-a-model-of-the-pulmonary-epithelium-and-their-formulation-in-pressurized-metered-dose-inhalers
#13
Rodrigo S Heyder, Qian Zhong, Reinaldo C Bazito, Sandro R P da Rocha
The purpose of this study was to evaluate the effect of generation and surface PEGylation of degradable polyester-based dendrimers nanocarriers on their interactions with an in vitro model of the pulmonary epithelium as well as to assess the ability to formulate such carriers in propellant-based, portable oral-inhalation devices to determine their potential for local and systemic delivery of drugs to and through the lungs. Hydroxyl (-OH) terminated polyester dendrimers of generation 3 and 4 (G3, and G4) were synthesized using a divergent approach...
February 1, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28158920/the-geobiological-nitrogen-cycle-from-microbes-to-the-mantle
#14
A L Zerkle, S Mikhail
Nitrogen forms an integral part of the main building blocks of life, including DNA, RNA, and proteins. N2 is the dominant gas in Earth's atmosphere, and nitrogen is stored in all of Earth's geological reservoirs, including the crust, the mantle, and the core. As such, nitrogen geochemistry is fundamental to the evolution of planet Earth and the life it supports. Despite the importance of nitrogen in the Earth system, large gaps remain in our knowledge of how the surface and deep nitrogen cycles have evolved over geologic time...
February 3, 2017: Geobiology
https://www.readbyqxmd.com/read/28157792/ultrasound-guided-costoclavicular-brachial-plexus-block-sonoanatomy-technique-and-block-dynamics
#15
Jia Wei Li, Banchobporn Songthamwat, Winnie Samy, Xavier Sala-Blanch, Manoj Kumar Karmakar
BACKGROUND AND OBJECTIVES: This study aimed to describe in detail the relevant sonoanatomy, technique, and block dynamics of an ultrasound-guided costoclavicular brachial plexus block (BPB). METHODS: Thirty patients scheduled for hand or forearm surgery under a BPB underwent transverse ultrasound imaging of the medial infraclavicular fossa to identify the cords of the brachial plexus at the costoclavicular space (CCS). An ultrasound-guided BPB was then performed at the CCS with 20 mL of 0...
March 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28155224/symptomatic-inspiration-induced-atrio-ventricular-block-treated-with-pacemaker-implant
#16
Diego A Hoffmann, Andrés Nicolás Atamañuk, Graciela Aurora Ruiz, Raul Chirife, Maria Cristina Tentori, Simón Salzberg
BACKGROUND: The respiratory sinus arrhythmia (RSA) is the most common cardiac arrhythmia. It consists of phasic variations of sinus cycle length produced by an autonomic reflex, and is characterized by increased heart rate during inspiration and decline in expiration. This phenomenon is due to a reduction of the parasympathetic tone during inspiration, causing a rise in the heart rate, while during expiration the opposite phenomenon occurs. This arrhythmia is more frequent in young adults, although it can also be seen in any age group...
February 3, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28149139/can-we-perform-distal-nerve-block-instead-of-brachial-plexus-nerve-block-under-ultrasound-guidance-for-hand-surgery
#17
Ilker Ince, Mehmet Aksoy, Mine Celik
OBJECTIVE: Distal nerve blocks are used in the event of unsuccessful blocks as rescue techniques. The primary purpose of this study was to determine the sufficiency for anesthesia of distal nerve block without the need for deep sedation or general anesthesia. The secondary purpose was to compare block performance times, block onset times, and patient and surgeon satisfaction. MATERIALS AND METHODS: Patients who underwent hand surgery associated with the innervation area of the radial and median nerves were included in the study...
October 2016: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28139468/a-review-on-single-photon-sources-in-silicon-carbide
#18
A Lohrmann, B C Johnson, J C McCallum, S Castelletto
This paper summarizes key findings in single-photon generation from deep level defects in silicon carbide (SiC) and highlights the significance of these individually addressable centers for emerging quantum applications. Single photon emission from various defect centers in both bulk and nanostructured SiC are discussed as well as their formation and possible integration into optical and electrical devices. The related measurement protocols, the building blocks of quantum communication and computation network architectures in solid state systems, are also summarized...
January 31, 2017: Reports on Progress in Physics
https://www.readbyqxmd.com/read/28134755/combining-champ-and-swarm-satellite-data-to-invert-the-lithospheric-magnetic-field-in-the-tibetan-plateau
#19
Yaodong Qiu, Zhengtao Wang, Weiping Jiang, Bingbing Zhang, Fupeng Li, Fei Guo
CHAMP and Swarm satellite magnetic data are combined to establish the lithospheric magnetic field over the Tibetan Plateau at satellite altitude by using zonal revised spherical cap harmonic analysis (R-SCHA). These data are integrated with geological structures data to analyze the relationship between magnetic anomaly signals and large-scale geological tectonic over the Tibetan Plateau and to explore the active tectonic region based on the angle of the magnetic anomaly. Results show that the model fitting error is small for a layer 250-500 km high, and the RMSE of the horizontal and radial geomagnetic components is better than 0...
January 26, 2017: Sensors
https://www.readbyqxmd.com/read/28128875/an-ultrasound-guided-tendon-sparing-lateral-approach-to-injection-of-the-navicular-bursa
#20
K Nottrott, C De Guio, A Khairoun, M Schramme
BACKGROUND: Navicular disease in the horse often requires injection of the navicular bursa. We have developed an ultrasound-guided, lateral needle approach to navicular bursocentesis, which avoids penetration of the deep digital flexor tendon (DDFT) and the need for radiographic control. OBJECTIVES: To describe and evaluate the feasibility and efficacy of an ultrasound-guided, lateral bursocentesis technique. STUDY DESIGN: Cadaveric and in vivo experiments...
January 27, 2017: Equine Veterinary Journal
keyword
keyword
88947
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"