Read by QxMD icon Read

selective intrauterine growth restriction

Rosemary Townsend, Asma Khalil
PURPOSE OF REVIEW: Selective intrauterine growth restriction (sIUGR) in twin pregnancies presents a complex management problem for the fetal medicine specialist. This review summarizes what is currently known about sIUGR pathophysiology, particularly in monochorionic pregnancies and looks at the results of early trials of fetal intervention in high-risk sIUGR pregnancies. RECENT FINDINGS: sIUGR in monochorionic pregnancies is due to unequal placental sharing, but the clinical outcome is determined by the characteristics of the placental vascular anastomoses...
October 15, 2016: Current Opinion in Obstetrics & Gynecology
Liran Hiersch, Mayan Eitan, Eran Ashwal, Boaz Weisz, Benny Chayen, Shlomo Lipitz, Yoav Yinon
OBJECTIVE: To estimate the risk for twin anemia-polycythemia sequence (TAPS) and adverse perinatal outcome in monochorionic diamniotic (MCDA) twin pregnancies with amniotic fluid discordance (AFD). METHODS: Retrospective cohort study of 34 MCDA pregnancies with AFD (intertwin difference of ≥3 cm in maximal vertical pocket measurement) without meeting the criteria for twin to twin transfusion syndrome (TTTS) or selective intrauterine growth restriction (sIUGR)...
October 12, 2016: Prenatal Diagnosis
Chang Duan, Min Liu, Haiyan Xu, Weiwei Tang, Jiayun Liu, Lamei Hou, Lijuan Li
Rats with intrauterine growth retardation and catch-up growth (CG-IUGR) after birth show increased susceptibility to diabetes mellitus in adulthood. The expression of glucose transporter type 4 (GLUT4) decreases in female IUGR offspring rats with seminutrient restriction during pregnancy. However, the male CG-IUGR rats also display an increased susceptibility to diabetes mellitus in adulthood. Whether there is another factor, besides GLUT4, in male CG-IUGR rat that mediates their susceptibility to diabetes mellitus? The male IUGR rats with catch-up growth were selected as the research objects...
October 2016: Acta Biochimica et Biophysica Sinica
Stephen Hodgins, James Tielsch, Kristen Rankin, Amber Robinson, Annie Kearns, Jacquelyn Caglia
BACKGROUND: Although this is beginning to change, the content of antenatal care has been relatively neglected in safe-motherhood program efforts. This appears in part to be due to an unwarranted belief that interventions over this period have far less impact than those provided around the time of birth. In this par, we review available evidence for 21 interventions potentially deliverable during pregnancy at high coverage to neglected populations in low income countries, with regard to effectiveness in reducing risk of: maternal mortality, newborn mortality, stillbirth, prematurity and intrauterine growth restriction...
2016: PloS One
E Álvarez-Silvares, M Vilouta-Romero, E Borrajo-Hernández, M L Morales-Serrano, M T Alves-Pérez
BACKGROUND: Some disorders of pregnancy and newborn have been associated with vitamin D deficiency (25 (OH) D) in maternal serum. The pathophysiology of this relationship is unknown today. OBJECTIVE: The aim of this study was to determine whether serum levels of vitamin D at the beginning of pregnancy are associated with gestational diabetes, hypertensive disorders of pregnancy, preterm birth and fetal growth restriction. MATERIAL AND METHOD: We conducted a prospective cohort study in 370 pregnant women at low obstetric risk randomly selected in our area (latitude 42 ° 20'N)...
March 2016: Ginecología y Obstetricia de México
K P Singh, Manoj K Singh, Shrikant Gautam
For clinical management of different forms of psychosis, both classical and atypical anti-psychotic drugs (APDs) are available. These drugs are widely prescribed, even during pregnancy considering their minimal extra-pyramidal side effects and teratogenic potential compared to classical APDs. Among AAPDs, risperidone (RIS) is a first-line drug of choice by physicians. The molecular weight of RIS is 410.49 g/mol; hence, it can easily cross the placental barrier and enter the foetal bloodstream. It is not known whether or not AAPDs like RIS may affect the developing placenta and foetus adversely...
April 2016: International Journal of Experimental Pathology
I Aditya, V Tat, A Sawana, A Mohamed, R Tuffner, T Mondal
Intrauterine growth restriction (IUGR) is a condition which has been difficult to assess at an early stage, resulting in the delivery of children who have poor genetic growth potential. Currently, IUGR classification is based upon the system of ultrasound biometry. Doppler velocimetry allows the measurement of hemodynamic flow of major fetal vessels, comparing the flow indices and patterns of normal and IUGR cases. In this review, the effectiveness of Doppler velocimetry in assessing blood flow in major vessels including the umbilical artery, ductus venosus, and middle cerebral artery was studied for both diagnostic and prognostic screening of IUGR...
May 18, 2016: Journal of Neonatal-perinatal Medicine
Meike Schuster, Obianuju Sandra Madueke-Laveaux, A Dhanya Mackeen, Wen Feng, Michael J Paglia
BACKGROUND: Obesity in pregnancy has an impact on both the mother and the fetus. To date, no universal protocol has been established to guide the management of pregnancy in obese woman. In April 2011, the Geisinger Maternal-Fetal Medicine Department implemented an obesity protocol in which women meeting the following criteria were delivered by their estimated due dates: (1) class III obese or (2) class II obese with additional diagnoses of a large-for-gestational-age fetus or pregnancy complicated by gestational diabetes or (3) class I obese with large-for-gestational-age and gestational diabetes...
October 2016: American Journal of Obstetrics and Gynecology
Zhao Tong, Zhang Xiaowen, Chen Baomin, Liu Aihua, Zhou Yingying, Teng Weiping, Shan Zhongyan
The objective of this study was to evaluate the association between maternal subclinical thyroid dysfunction and autoimmunity with the risk for intrauterine growth restriction (IUGR).Design is a systematic review and meta-analysis.A literature search was conducted using PubMed, Embase, and Cochrane database. A combination of 2 key words was used to search for the eligible studies: one indexed thyroid dysfunction or antithyroid antibodies; and the other one indexed the adverse neonatal outcomes of pregnancy, such as IUGR, small for gestational age, fetal growth restriction, or low birth weight...
May 2016: Medicine (Baltimore)
Jackeline Christiane Pinto Lobato, Antonio José Leal Costa, Pauline Lorena Kale, Maria de Lourdes Tavares Cavalcanti, Maria Cristina Caetano Kuschnir, Luis Guillermo Coca Velarde, Antonio Cláudio Lucas da Nóbrega, Beni Olej, Luciana de Barros Duarte, Moyses Szklo
OBJECTIVE: To describe the methodological features of a study on the association between restricted intrauterine growth and prevalence of overweight, obesity and hypertension in school aged children. METHODS: The study was conducted in two stages in two public schools in Niterói (RJ), from June through December 2010. All students aged 6 to 14 years were eligible to participate. The first stage consisted of an interview to collect information on demographic variables, diet and other variables...
March 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Olivier Laurent, Jianlin Hu, Lianfa Li, Michael J Kleeman, Scott M Bartell, Myles Cockburn, Loraine Escobedo, Jun Wu
INTRODUCTION: Intrauterine growth restriction has been associated with exposure to air pollution, but there is a need to clarify which sources and components are most likely responsible. This study investigated the associations between low birth weight (LBW, <2500g) in term born infants (≥37 gestational weeks) and air pollution by source and composition in California, over the period 2001-2008. METHODS: Complementary exposure models were used: an empirical Bayesian kriging model for the interpolation of ambient pollutant measurements, a source-oriented chemical transport model (using California emission inventories) that estimated fine and ultrafine particulate matter (PM2...
July 2016: Environment International
Yao-Lung Chang, An-Shine Chao, Hsiu-Huei Peng, Shuenn-Dyh Chang, Sheng-Yuan Su, Kuan-Ju Chen, Po-Jen Cheng, Tzu-Hao Wang
Hypoxia is the primary stimulus for the production of erythropoietin (EPO) in both fetal and adult life. Here, we investigated fetal plasma EPO concentrations in monochorionic (MC) twin pregnancies with selective intrauterine growth restriction (sIUGR) and abnormal umbilical artery (UA) Doppler. We diagnosed sIUGR in presence of (1) birth-weight discordance >20% and (2) either twin with a birth weight <10th percentile. An abnormal UA Doppler was defined as a persistent absent-reverse end diastolic flow (AREDF)...
August 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
Horacio Figueroa, Jorge Cifuentes, Mauricio Lozano, Cristobal Alvarado, Claudia Cabezas, Elisenda Eixarch, Ellio Fernández, Luis Contreras, Sebastian E Illanes, Edgar Hernández-Andrade, Eduard Gratacós, Carlos E Irarrazabal
OBJECTIVE: This work aimed to study the effect of uteroplacental circulation restriction on endothelial kidney damage in a fetal rabbit model. METHODS: New Zealand rabbits were subjected to 40% to 50% of uteroplacental artery ligation at day 25 of pregnancy. After 5 days, surviving fetuses were harvested by cesarean section. The gene and protein expressions of selected enzymes associated with nitric oxide production and oxidative stress were analyzed in fetal kidney homogenates...
July 2016: Prenatal Diagnosis
Marianne Jacques, Thomas Freour, Paul Barriere, Stéphane Ploteau
To assess the impact of endometriosis on obstetric outcomes and to determine whether the severity, location and surgical treatment of the disease before the pregnancy had an impact on the prevalence of these disorders, a monocentric, case-control study was performed. In total, 113 pregnancies obtained by assisted reproductive treatment among patients with endometriosis were matched with control selected among assisted reproductive treatment pregnancies due to male infertility. The main result measures were pregnancy outcome at the obstetrical and neo-natal levels...
June 2016: Reproductive Biomedicine Online
Maria Angela Rustico, Dario Consonni, Mariano Lanna, Stefano Faiola, Vito Schena, Barbara Scelsa, Paola Introvini, Andrea Righini, Cecilia Parazzini, Gianluca Lista, Francesco Barretta, Enrico Ferrazzi
OBJECTIVE: To describe changes in the umbilical artery (UA) Doppler flow of monochorionic diamniotic (MC DA) twins with selective intrauterine growth restriction (sIUGR), to correlate Doppler findings with pregnancy course and perinatal outcome, to report postnatal follow up. METHODS: Retrospective study of 140 MC DA twins with sIUGR. UA end-diastolic flow, defined as pattern Type I (persistently positive), Type II (persistently absent or persistently reversed), and Type III (intermittent) was recorded at first examination and monitored weekly until double or single fetal death, bipolar cord coagulation, or delivery...
April 7, 2016: Ultrasound in Obstetrics & Gynecology
Isin Ureyen, Ozgur Ozyuncu, Nihal Sahin-Uysal, Ozgur Kara, Derman Basaran, Mert Turgal, Ozgur Deren
OBJECTIVE: In this study, we investigated the relationship of mean platelet volume (MPV) with the presence and the severity of intrauterine growth restriction (IUGR) and with neonatal complications. METHODS: The pregnancies with and without IUGR, that were followed-up in our hospital between 2003 and 2009 were analyzed retrospectively. Pregnancies which resulted in birth of a newborn with a birthweight less than 10th percentile for the gestational age were selected for IUGR group...
April 28, 2016: Journal of Maternal-fetal & Neonatal Medicine
Amber Hill, Christina Pallitto, Jennifer McCleary-Sills, Claudia Garcia-Moreno
BACKGROUND: Intimate partner violence (IPV) has a detrimental impact on the lives of women worldwide. Several studies have examined the effect IPV has on adverse birth outcomes when it occurs during pregnancy. OBJECTIVES: To explore the association between IPV and selected adverse birth outcomes. SEARCH STRATEGY: Multiple databases were searched to identify studies investigating the association between IPV and low birth weight (LBW), preterm birth, and/or intrauterine growth restriction (IUGR)...
June 2016: International Journal of Gynaecology and Obstetrics
Ruan Peng, Hong-Ning Xie, Mei-Fang Lin, Jian-Bo Yang, Yi Zhou, Hui-Qing Chen, Yun-Xiao Zhu
AIMS: To review pregnancy outcomes, complication rates and neonatal neural development of selective termination procedures for complicated monochorionic (MC) twins. METHODS: This was a retrospective review of the pregnancies that underwent selective reduction with radiofrequency ablation (RFA) and bipolar cord coagulation (BCC) in our institution. RESULTS: Forty-eight cases underwent selective reduction with BCC and the remaining 45 with RFA...
April 2, 2016: Gynecologic and Obstetric Investigation
Ellen Hinch, Amanda Henry, Isabella Wilson, Alec W Welsh
OBJECTIVES: To investigate rates of progression, regression and stabilisation and outcomes for stage I twin-twin transfusion syndrome (TTTS) and significant liquor discordant (LD) monochorionic diamniotic (MCDA) twins referred to the New South Wales Fetal Therapy Centre between June 2007 and May 2013. METHODS: Retrospective cohort study of 329 monochorionic referrals, of whom 47 had LD and 28 had stage I TTTS at presentation; 43 were stage I or higher at any time during surveillance...
June 2016: Prenatal Diagnosis
Juncao Chen, Pingyang Chen, Tao Bo, Kaiju Luo
CONTEXT: Children who experienced intrauterine growth restriction (IUGR) may be at increased risk for adverse neurologic developmental outcomes during the school-age years of life. OBJECTIVE: To estimate the effect of IUGR on cognition and behavior in school-aged children. DATA SOURCES: Medline, Embase, and PsycINFO were searched for English-language articles published after 1980. DATA SELECTION: We included case-control studies reporting cognitive and/or behavioral data of children who had IUGR and were evaluated afterfifth birthday...
April 2016: Pediatrics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"