keyword
https://read.qxmd.com/read/38717274/a-neural-network-based-algorithm-for-the-reconstruction-and-filtering-of-single-particle-trajectory-in-magnetic-particle-tracking
#1
JOURNAL ARTICLE
Mohit Prashanth, Pan Du, Jian-Xun Wang, Huixuan Wu
Magnetic particle tracking (MPT) is a recently developed non-invasive measurement technique that has gained popularity for studying dense particulate or granular flows. This method involves tracking the trajectory of a magnetically labeled particle, the field of which is modeled as a dipole. The nature of this method allows it to be used in opaque environments, which can be highly beneficial for the measurement of dense particle dynamics. However, since the magnetic field of the particle used is weak, the signal-to-noise ratio is usually low...
May 1, 2024: Review of Scientific Instruments
https://read.qxmd.com/read/38716295/attitudes-toward-menstrual-suppression-among-cyclic-and-continuous-contraceptive-vaginal-ring-users-in-kenya
#2
JOURNAL ARTICLE
Kristina Wilbekin Walker, Nelly Mugo, Kenneth Ngure, Stephen Gakuo, Edinah Casmir, Howard Wiener, Dustin Long, Sadeep Shrestha, Jeanne Marrazzo
OBJECTIVE: Multipurpose prevention technologies (MPTs) are developmental dual-purpose options that would provide women with a contraceptive as well as a prevention modality aimed at sexually transmitted infections. The contraceptive vaginal ring (CVR) has many properties that makes it an ideal MPT candidate. The objective of this study is to understand women's attitudes towards menstrual suppression, a potential side effect of using a CVR, and how to address these attitudes for MPT vaginal rings in development...
September 2023: Journal of Family & Reproductive Health
https://read.qxmd.com/read/38714576/influence-of-psychometric-and-sleep-quality-features-on-painful-mechanical-sensitivity-and-pain-modulation-in-patients-with-temporomandibular-disorders
#3
JOURNAL ARTICLE
Rafaela Stocker Salbego, Paulo César Rodrigues Conti, Flávia Fonseca Carvalho Soares, Dyna Mara Araújo Oliveira Ferreira, Matheus Herreira-Ferreira, Beatriz Amaral de Lima-Netto, Peter Svensson, Yuri Martins Costa, Leonardo Rigoldi Bonjardim
UNLABELLED: Investigating the collective impact of psychometric properties and sleep quality on pain sensitivity in temporomandibular disorder (TMD) patients could improve clinical management strategies. OBJECTIVE: Assessing whether combined psychometric properties and sleep quality impact painful mechanical sensitivity and pain modulation in TMD patients. MATERIALS AND METHODS: A cross-sectional study using secondary data analysis of 77 TMD patients and 101 controls...
May 7, 2024: Clinical Oral Investigations
https://read.qxmd.com/read/38714438/a-comparison-of-the-dysphonia-severity-index-and-singing-voice-handicap-index-between-trained-and-untrained-male-iranian-traditional-singers
#4
JOURNAL ARTICLE
Mohadesehalsadat Hosseiniheshmatian, Akbar Darouie, Arezoo Hasanvand, Enayatollah Bakhshi
OBJECTIVES: This study aimed to compare trained and untrained Iranian traditional singers on the Dysphonia Severity Index (DSI) and the Singing Voice Handicap Index. The second objective was to examine the relationship between the DSI and Persian version of the Singing Voice Handicap Index (P-SVHI) scores in each group of trained and untrained Iranian traditional singers. STUDY DESIGN: This study is a comparative cross-sectional study. METHODS: This study included 17 trained male Iranian traditional singers who were compared with 17 untrained ones who were matched in terms of age...
May 6, 2024: Journal of Voice
https://read.qxmd.com/read/38711218/single-cell-transcriptome-landscape-and-cell-fate-decoding-in-human-brain-organoids-after-transplantation
#5
JOURNAL ARTICLE
Shi-Bo Xu, Xin-Rui Li, Pan Fan, Xiyang Li, Yuan Hong, Xiao Han, Shanshan Wu, Chu Chu, Yuejun Chen, Min Xu, Mingyan Lin, Xing Guo, Yan Liu
Human stem cells and derivatives transplantation are widely used to treat nervous system diseases, while the fate determination of transplanted cells is not well elucidated. To explore cell fate changes of human brain organoids before and after transplantation, human brain organoids are transplanted into prefrontal cortex (PFC) and hippocampus (HIP), respectively. Single-cell sequencing is then performed. According to time-series sample comparison, transplanted cells mainly undergo neural development at 2 months post-transplantation (MPT) and then glial development at 4MPT, respectively...
May 6, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38710224/rehabilitation-program-for-post-laryngectomy-patients-following-ileocolon-flap-transfer-for-voice-reconstruction-an-essential-part-of-success
#6
JOURNAL ARTICLE
Katie Kai-Yuan Lin, Chi-Wen Huang, Shih-Heng Chen, Jian-Jr Lee, Hung-Chi Chen
BACKGROUND: Speech restoration is important for communication and social activities after pharyngolaryngectomy in head and neck cancer or corrosive injury. Several techniques of voice restoration have been developed to improve life quality. The aim of this paper was to focus on the microsurgical transfer of ileocolon flap and outcome of further voice rehabilitation. PATIENTS AND METHODS: From 2010 to 2022, 69 patients had ileocolon flap at our hospital with postoperative speech training and regular follow-up for over one year...
May 6, 2024: Journal of Reconstructive Microsurgery
https://read.qxmd.com/read/38706893/constructing-a-prognostic-model-of-uterine-corpus-endometrial-carcinoma-and-predicting-drug-sensitivity-responses-using-programmed-cell-death-related-pathways
#7
JOURNAL ARTICLE
Jingwen Meng, Chen Zong, Meixia Wang, Yu Chen, Shaojie Zhao
Background: Uterine Corpus Endometrial Carcinoma (UCEC) is the most common type of cancer that develops in the uterus, specifically originating from the endometrium, the inner lining of the uterus. Programmed cell death (PCD) is a highly regulated process that eliminates damaged, aged, or unwanted cells in the body. Dysregulation of PCD pathways can contribute to the formation and progression of various cancers, including UCEC. Methods: Fourteen PCD pathways (autophagy-dependent cell death, alkaliptosis, apoptosis, cuproptosis, entotic cell death, ferroptosis, immunogenic cell death, lysosome-dependent cell death, MPT-driven necrosis, necroptosis, netotic cell death, oxeiptosis, parthanatos, and pyroptosis) were involved in building a prognostic signature...
2024: Journal of Cancer
https://read.qxmd.com/read/38706594/malignant-phyllodes-tumor-of-the-breast-with-predominant-osteosarcoma-and-chondrosarcomatous-differentiation-a-rare-case-report-and-review-of-literature
#8
Wenfang Li, Qin Ou, Yingdong Li, Linlin Yuan Yuan
BACKGROUND: Phyllodes tumors (PTs), which account for less than 1% of mammary gland tumors, composed of both epithelial and stromal components. If a malignant heterologous component is encountered, PT is considered malignant. Malignant phyllodes tumors (MPTs) only account for 8% to 20% of PTs. We report a case of MPT with osteosarcoma and chondrosarcoma differentiation and review the literature to discuss the differential diagnosis and therapy. CASE PRESENTATION: A 59-year-old Chinese woman come to our hospital because of a palpable mass she had had for 1 months in the left breast...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38700335/innate-phase-production-of-ifn-%C3%AE-by-memory-and-effector-t-cells-expressing-early-activation-marker-cd69-during-infection-with-cryptococcus-deneoformans-in-the-lungs
#9
JOURNAL ARTICLE
Anna Miyahara, Aya Umeki, Ko Sato, Toshiki Nomura, Hideki Yamamoto, Tomomitsu Miyasaka, Daiki Tanno, Ikumi Matsumoto, Tong Zong, Takafumi Kagesawa, Akiho Oniyama, Kotone Kawamura, Xiaoliang Yuan, Rin Yokoyama, Yuki Kitai, Emi Kanno, Hiromasa Tanno, Hiromitsu Hara, Sho Yamasaki, Shinobu Saijo, Yoichiro Iwakura, Keiko Ishii, Kazuyoshi Kawakami
Cryptococcus deneoformans is a yeast-type fungus that causes fatal meningoencephalitis in immunocompromised patients and evades phagocytic cell elimination through an escape mechanism. Memory T (Tm) cells play a central role in preventing the reactivation of this fungal pathogen. Among these cells, tissue-resident memory T (TRM ) cells quickly respond to locally invaded pathogens. This study analyzes the kinetics of effector T (Teff) cells and Tm cells in the lungs after cryptococcal infection. Emphasis is placed on the kinetics and cytokine expression of TRM cells in the early phase of infection...
May 3, 2024: Infection and Immunity
https://read.qxmd.com/read/38693900/on-the-hunt-for-the-missed-genetic-causes-of-multiple-primary-tumors
#10
JOURNAL ARTICLE
Fiona Chan-Pak-Choon, William D Foulkes
Improved cancer screening and treatment programs have led to an increased survivorship of patients with cancer, but consequently also to the rise in number of individuals with multiple primary tumors (MPT). Germline testing is the first approach investigating the cause of MPT, as a positive result provides a diagnosis and proper clinical management to the affected individual and their family. Negative or inconclusive genetic results could suggest non-genetic causes, but are negative genetic results truly negative? Herein, we discuss the potential sources of missed genetic causes and highlight the trove of knowledge MPT can provide...
May 2, 2024: Cancer Prevention Research
https://read.qxmd.com/read/38690425/impact-of-maximum-phonation-time-on-postoperative-dysphagia-and-prognosis-after-cardiac-surgery
#11
JOURNAL ARTICLE
Masato Ogawa, Seimi Satomi-Kobayashi, Mari Hamaguchi, Kodai Komaki, Hifumi Kusu, Kazuhiro P Izawa, Shunsuke Miyahara, Yoshitada Sakai, Ken-Ichi Hirata, Kenji Okada
OBJECTIVE: The incidence of postoperative complications, including dysphagia, increases as the population undergoing cardiovascular surgery ages. This study aimed to explore the potential of maximum phonation time (MPT) as a simple tool for predicting postextubation dysphagia (PED) and major adverse cardiac and cerebrovascular events (MACCEs). METHODS: This retrospective study included 442 patients who underwent elective cardiac surgery at a university hospital...
April 2024: JTCVS open
https://read.qxmd.com/read/38687780/acoustic-wave-induced-ferh-magnetic-phase-transition-and-its-application-in-antiferromagnetic-pattern-writing-and-erasing
#12
JOURNAL ARTICLE
Huiliang Wu, Qingfang Liu, Runliang Gao, Shuai Mi, Lei Jia, Jianing Wang, Huibo Liu, Senfu Zhang, Jinwu Wei, Xiangqian Wang, Genliang Han, Jianbo Wang
We explore the FeRh magnetic phase transition (MPT) and magnetic phase domain (MPD) with the introduction of surface acoustic waves (SAWs). The effects of the SAW pulses with different pulse widths and powers on resistance-temperature loops are investigated, revealing that the SAW can reduce the thermal hysteresis. Meanwhile, the SAW-induced comb-like antiferromagnetic (AFM) phase domains are observed. By changing the pulse width and SAW frequency, we further realize a writing-erasing process of the different comb-like AFM phase domains in the mixed-phase regime of the cooling transition branch...
April 30, 2024: ACS Nano
https://read.qxmd.com/read/38684845/a-link-between-circulating-immune-complexes-and-acute-kidney-injury-in-human-visceral-leishmaniasis
#13
JOURNAL ARTICLE
Gabriela Corrêa-Castro, Maria Luciana Silva-Freitas, Ludmila de Paula, Leonardo Soares Pereira, Maria Rita Teixeira Dutra, Hermano Gomes Albuquerque, Glaucia Cota, Caroline de Azevedo Martins, Alda Maria Da-Cruz, Adriano Gomes-Silva, Joanna Reis Santos-Oliveira
Visceral leishmaniasis (VL) is an infectious disease caused by Leishmania infantum. Clinically, VL evolves with systemic impairment, immunosuppression and hyperactivation with hypergammaglobulinemia. Although renal involvement has been recognized, a dearth of understanding about the underlying mechanisms driving acute kidney injury (AKI) in VL remains. We aimed to evaluate the involvement of immunoglobulins (Igs) and immune complexes (CIC) in the occurrence of AKI in VL patients. Fourteen VL patients were evaluated between early treatment and 12 months post-treatment (mpt)...
April 30, 2024: Scientific Reports
https://read.qxmd.com/read/38661378/association-of-perioperative-oral-swallowing-function-with-post-esophagectomy-outcomes-and-nutritional-statuses-in-patients-with-esophageal-cancer
#14
JOURNAL ARTICLE
Sohei Matsumoto, Kohei Wakatsuki, Hiroshi Nakade, Tomohiro Kunishige, Shintaro Miyao, Satoko Aoki, Akinori Tsujimoto, Takanari Tatsumi, Masahiro Soga, Masayuki Sho
Dysphagia after esophagectomy is a serious complication; however, no method has been established to accurately assess swallowing function. We evaluated the association of swallowing function tests with patients' post-esophagectomy complications and nutritional statuses. We retrospectively reviewed the data of 95 patients with esophageal cancer who underwent esophagectomy between 2016 and 2021. We performed perioperative swallowing function tests, including the repetitive saliva swallowing test (RSST), maximum phonation time (MPT), and laryngeal elevation (LE)...
April 25, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38649315/can-we-use-the-maximum-phonation-time-as-a-screening-of-pulmonary-forced-vital-capacity-in-post-covid-19-syndrome-patients
#15
JOURNAL ARTICLE
Juliana Alves Souza, Adriane Schmidt Pasqualoto, Carla Aparecida Cielo, Débora Bonesso Andriollo, Denis Altieri Oliveira Moraes
OBJECTIVE: To verify the accuracy of the maximum phonation time of the vowel /a/ (MPT/a/), fricative /s/ (MPT/s/), number counting (MPTC), and number reached in this count (CN) to estimate forced vital capacity (FVC) in patients with post-COVID-19 syndrome. METHOD: Cross-sectional study involving adult patients, who were admitted to the intensive care unit and referred to the Post-COVID-19 Rehabilitation Outpatient Clinic. Voice function was assessed using a Vocal Handicap Index (VHI) self-assessment questionnaire and MPT tests...
April 21, 2024: Journal of Voice
https://read.qxmd.com/read/38642524/effect-of-voice-training-intervention-on-swallowing-function-in-patients-with-head-and-neck-cancer-undergoing-radiotherapy-a-randomized-controlled-trial
#16
JOURNAL ARTICLE
Yan Liu, Ran Hou, Qinqin Yu, Qiaohong Niu
PURPOSE: We aimed to evaluate the effect of voice training in patients with head and neck cancer who were undergoing radiotherapy. METHOD: This study used a randomized controlled trial design. IBM SPSS 26.0 was used to randomly divide 74 patients into a control group and an experimental group. The control group followed a swallowing exercises program, and the experimental group additionally received ABCLOVE voice training. Both training programs continued throughout the entire radiotherapy cycle...
March 15, 2024: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://read.qxmd.com/read/38639510/analysis-of-factors-on-voice-quality-in-thyroidectomy-patients
#17
JOURNAL ARTICLE
S Subaşi, Ö Dere, S Şahin, Ç Gökdoğan, I Kayilioğlu, C Yazkan, Ö Özcan
OBJECTIVE: Vocal cord paralysis (VCP) is a serious complication in thyroidectomy operations; however, its management remains unclear. The present study evaluated the voice parameters of patients who underwent surgery using Intraoperative Neurophysiologic Monitoring (IONM). PATIENTS AND METHODS: A total of 52 patients (41 females and 11 males) who underwent a total thyroidectomy operation were evaluated using objective and subjective voice analysis examinations before and after surgery...
April 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38638666/lunotriquetral-synostosis-as-a-cause-of-ulnar-sided-wrist-pain-a-case-report
#18
Mpt Alves
The diagnostic workout of ulnar sided wrist pain may be challenging, since there can be many different causes for it, varying from ulnar nerve problems to fractures. Congenital lunotriquetral synostosis may present as a source of pain in some cases, but it is a rare diagnosis. The author presents a case of post-traumatic ulnar sided wrist pain in a patient with Minnaar's type 1 congenital lunotriquetral synostosis.
March 2024: Malaysian Orthopaedic Journal
https://read.qxmd.com/read/38636302/effect-of-2-aminoethoxydiphenyl-borate-on-the-functions-of-mouse-skeletal-muscle-mitochondria
#19
JOURNAL ARTICLE
Mikhail V Dubinin, Alexander V Chulkov, Anastasia D Igoshkina, Alena A Cherepanova, Natalia V Mikina
This work examined the effect of 2-aminoethoxydiphenyl borate (2-APB) on the functioning of isolated mouse skeletal muscle mitochondria and modeled its putative interaction with mitochondrial proteins. We have shown that 2-APB is able to dose-dependently suppress mitochondrial respiration in state 3 and 3UDNP driven by substrates of complex I and II. This effect of 2-APB was accompanied by a slight dose-dependent decrease in mitochondrial membrane potential and appears to be due to inhibition of complex I and complex III of the electron transport chain (ETC) with IC50 values of 200 and 120 μM, respectively...
April 16, 2024: Biochemical and Biophysical Research Communications
https://read.qxmd.com/read/38627323/refining-bayesian-hierarchical-mpt-modeling-integrating-prior-knowledge-and-ordinal-expectations
#20
JOURNAL ARTICLE
Alexandra Sarafoglou, Beatrice G Kuhlmann, Frederik Aust, Julia M Haaf
Multinomial processing tree (MPT) models are a broad class of statistical models used to test sophisticated psychological theories. The research questions derived from these theories often go beyond simple condition effects on parameters and involve ordinal expectations (e.g., the same-direction effect on the memory parameter is stronger in one experimental condition than another) or disordinal expectations (e.g., the effect reverses in one experimental condition). Here, we argue that by refining common modeling practices, Bayesian hierarchical models are well suited to estimate and test these expectations...
April 16, 2024: Behavior Research Methods
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