keyword
MENU ▼
Read by QxMD icon Read
search

mpt

keyword
https://www.readbyqxmd.com/read/28345678/laryngeal-manual-therapy-palpatory-evaluation-scale-a-preliminary-study-to-examine-its-usefulness-in-diagnosis-of-occupational-dysphonia
#1
Ewelina Woźnicka, Ewa Niebudek-Bogusz, Joanna Morawska, Justyna Wiktorowicz, Mariola Śliwińska-Kowalska
BACKGROUND: The aim of this study has been to assess the larynx and soft tissue around the vocal tract in a group of people with healthy voice, and in a group of patients with occupational dysphonia using the new laryngeal manual therapy palpatory evaluation scale (LMTPE). MATERIAL AND METHODS: The examinations were performed in a study (dysphonic) group of professional voice users who had developed voice disorders (N = 51) and in the control group of normophonic subjects (N = 50)...
March 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28333630/multilinear-spatial-discriminant-analysis-for-dimensionality-reduction
#2
Sen Yuan, Xia Mao, Lijiang Chen
In the last few years, great efforts have been made to extend linear projection technique (LPT) for multidimensional data (i.e. tensor), generally referred to as multilinear projection technique (MPT). The vectorized nature of LPT requires high dimensional data to be converted to vector, hence may lose spatial neighborhood information of raw data. MPT well addresses this problem by encoding multidimensional data as general tensors of second or even higher order. In this paper, we propose a novel multilinear projection technique, called multilinear spatial discriminant analysis (MSDA), to identify the underlying manifold of high-order tensor data...
March 21, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28320189/tempol-4-hydroxy-tempo-inhibits-anoxia-induced-progression-of-mitochondrial-dysfunction-and-associated-neurobehavioral-impairment-in-neonatal-rats
#3
Puneet K Samaiya, Gopeshwar Narayan, Ashok Kumar, Sairam Krishnamurthy
BACKGROUND: Anoxia leads to a robust generation of reactive oxygen species/nitrogen species which can result in mitochondrial dysfunction and associated cell death in the cerebral cortex of neonates. AIM: The present study investigated the pharmacological role of tempol in the treatment of rat neonatal cortical mitochondrial dysfunction induced insult progression (day-1 to day-7) and associated neurobehavioral alterations post-anoxia. METHODS: Rat pups of 30h age or postnatal day 2 (PND2) were randomly divided into 5 groups (n=5 per group): (1) Control; (2) Anoxia; (3) Anoxia+Tempol 75mg/kg; (4) Anoxia+Tempol 150mg/kg; and (5) Anoxia+Tempol 300mg/kg, and subjected to two episode of anoxia (10min each) at 24h of time interval in an enclosed chamber supplied with 100% N2...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28317798/nontuberculous-mycobacterial-species-and-mycobacterium-tuberculosis-complex-coinfection-in-patients-with-pulmonary-tuberculosis-in-dr-soetomo-hospital-surabaya-indonesia
#4
Ni Made Mertaniasih, Deby Kusumaningrum, Eko Budi Koendhori, Tutik Kusmiati, Desak Nyoman Surya Suameitria Dewi
OBJECTIVE/BACKGROUND: The aim of this study was to analyze the detection of nontuberculous mycobacterial (NTM) species derived from sputum specimens of pulmonary tuberculosis (TB) suspects. Increasing prevalence and incidence of pulmonary infection by NTM species have widely been reported in several countries with geographical variation. MATERIALS AND METHODS: Between January 2014 and September 2015, sputum specimens from chronic pulmonary TB suspect patients were analyzed...
January 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28315699/the-neglected-functions-of-intrinsically-disordered-proteins-and-the-origin-of-life
#5
REVIEW
Laurent Jaeken
The example of gelatine shows that extended proteins behave quite differently than globular ones: with water they form a gel. Historically the colloid view of protoplasm was discredited in favour of membrane-(pump)-theory (MPT), but unjustified. In his association-induction hypothesis Ling demonstrates that MPT is full of contradictions and that the colloid view has to be re-considered. In that case IDP's play a crucial role in this. What Ling calls the 'living state' consists of the unitary protoplasmic structure from which it was experimentally demonstrated that it can survive and keep Na(+) and K(+) concentrations without a delineating membrane...
March 15, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28300957/dosage-dependent-effect-of-high-resistance-straw-exercise-in-dysphonic-and-non-dysphonic-women
#6
Sabrina Mazzer Paes, Mara Behlau
Purpose: to study the dosage dependent effect of high-resistance straw exercise in women with behavioral dysphonia and in vocally healthy women. Methods: 25 dysphonic women (DG), with average age of 35 years (SD = 10.5) and 30 vocally healthy women (VHG), with average age of 31.6 years (SD = 10.3). The participants produced a continuous sound into a thin high-resistance straw for seven minutes, being interrupted after the first, third, fifth and seventh minute. At each interval, speech samples were recorded (sustained vowel and counting up to 20) and subsequently acoustically analyzed...
March 9, 2017: CoDAS
https://www.readbyqxmd.com/read/28296041/mitochondrial-oxidative-stress-and-dysfunction-induced-by-single-and-multi-wall-carbon-nanotubes-a-comparative-study
#7
Parvaneh Naserzadeh, Fatemeh Ghanbary, Enayatollah Seydi, Alireza Ghasemi, Mohammad Taghi Joghataei, Khadijeh Ashtari, Mohsen Akbari
With the ever-increasing use of carbon nanotubes (CNTs) in health-related and engineering applications, the hazardous risks of this material have become a major concern. It is well-known that CNTs accumulate with cytotoxic and genotoxic levels within vital organs. It has also been shown that treating cell cultures with CNTs resulted in cell cycle arrest and increased apoptosis/necrosis. The goal of this pilot study is to perform a comprehensive comparative study on the toxicity of single-wall (SW) and multi-wall (MW) carbon nanotubes in rat skin cells...
March 10, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28284974/mevalonolactone-disrupts-mitochondrial-functions-and-induces-permeability-transition-pore-opening-in-rat-brain-mitochondria-implications-for-the-pathogenesis-of-mevalonic-aciduria
#8
Cristiane Cecatto, Alexandre Umpierrez Amaral, Janaína Camacho da Silva, Alessandro Wajner, Kálita Dos Santos Godoy, Rafael Teixeira Ribeiro, Aline de Mello Gonçalves, Carmen Regla Vargas, Moacir Wajner
Mevalonic aciduria (MVA) is caused by severe deficiency of mevalonic kinase activity leading to tissue accumulation and high urinary excretion of mevalonic acid (MA) and mevalonolactone (ML). Patients usually present severe neurologic symptoms whose pathophysiology is poorly known. Here, we tested the hypothesis that the major accumulating metabolites are toxic by investigating the in vitro effects of MA and ML on important mitochondrial functions in rat brain and liver mitochondria. ML, but not MA, markedly decreased mitochondrial membrane potential (ΔΨm), NAD(P)H content and the capacity to retain Ca(2+) in the brain, besides inducing mitochondrial swelling...
March 8, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28284029/shared-function-and-moonlighting-proteins-in-molybdenum-cofactor-biosynthesis
#9
Silke Leimkühler
The biosynthesis of the molybdenum cofactor (Moco) is a highly conserved pathway in bacteria, archaea and eukaryotes. The molybdenum atom in Moco containing enzymes is coordinated to the dithiolene group of a tricyclic pyranopterin monophosphate cofactor. The biosynthesis of Moco can be divided into three conserved steps, with a fourth one present only in bacteria and archaea: 1) formation of cyclic pyranopterin monophosphate, 2) formation of molybdopterin (MPT), 3) insertion of molybdenum into MPT to form Mo-MPT, and 4) additional modification of Mo-MPT in bacteria with the attachment of a GMP or CMP nucleotide, forming the dinucleotide variants of Moco...
March 11, 2017: Biological Chemistry
https://www.readbyqxmd.com/read/28271554/examination-of-wound-healing-after-curettage-by-multiphoton-tomography-of-human-skin-in-vivo
#10
S Springer, M Zieger, A Böttcher, J Lademann, M Kaatz
BACKGROUND: The multiphoton tomography (MPT) has evolved into a useful tool for the non-invasive investigation of morphological and biophysical characteristics of human skin in vivo. Until now, changes of the skin have been evaluated mainly by using clinical and histological techniques. In this study, the progress of wound healing was investigated by MPT over 3 weeks with a final examination after 24 months. Especially, the collagen degradation, reepithelization and tissue formation were examined...
March 7, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28269986/differentiation-using-microwave-plasma-torch-desorption-mass-spectrometry-of-navel-oranges-cultivated-in-neighboring-habitats
#11
Xinchen Wang, Meiling Yang, Zhiyuan Wang, Hua Zhang, Guofeng Wang, Min Deng, Huanwen Chen, Liping Luo
The molecular fingerprinting of intact fruit samples combined with statistical data analysis can allow the assessment of fruit quality and location of origin. Herein, microwave plasma torch desorption ionization mass spectrometry (MPT-MS) was applied to produce molecular fingerprints for the juice sac and exocarp of navel oranges cultivated in three closely located habitats, and the mass spectrometric fingerprints were differentiated by principal component analysis (PCA). Because of the relatively high temperature and high ionization efficiency of MPT, the volatile aroma compounds and semivolatile chemicals in the navel oranges were sensitively detected and confidently identified by collision induced dissociation (CID)...
March 14, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28268129/responses-of-middle-frequency-modulations-in-vocal-fundamental-frequency-to-different-vocal-intensities-and-auditory-feedback
#12
Shao-Hsuan Lee, Tuan-Jen Fang, Jen-Fang Yu, Guo-She Lee
OBJECTIVES AND BACKGROUND: Auditory feedback can make reflexive responses on sustained vocalizations. Among them, the middle-frequency power of F0 (MFP) may provide a sensitive index to access the subtle changes in different auditory feedback conditions. MATERIALS AND METHODS: Phonatory airflow temperature was obtained from 20 healthy adults at two vocal intensity ranges under four auditory feedback conditions: (1) natural auditory feedback (NO); (2) binaural speech noise masking (SN); (3) bone-conducted feedback of self-generated voice (BAF); and (4) SN and BAF simultaneously...
March 3, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28251264/calcium-induced-mitochondrial-permeability-transitions-parameters-of-ca-2-ion-interactions-with-mitochondria-and-effects-of-oxidative-agents
#13
Nina G Golovach, Vitali T Cheshchevik, Elena A Lapshina, Tatsiana V Ilyich, Ilya B Zavodnik
We evaluated the parameters of Ca(2+)-induced mitochondrial permeability transition (MPT) pore formations, Ca(2+) binding constants, stoichiometry, energy of activation, and the effect of oxidative agents, tert-butyl hydroperoxide (tBHP), and hypochlorous acid (HOCl), on Ca(2+) -mediated process in rat liver mitochondria. From the Hill plot of the dependence of MPT rate on Ca(2+) concentration, we determined the order of interaction of Ca(2+) ions with the mitochondrial sites, n = 3, and the apparent Kd = 60 ± 12 µM...
March 1, 2017: Journal of Membrane Biology
https://www.readbyqxmd.com/read/28210881/comprehensive-genomic-profiling-of-malignant-phyllodes-tumors-of-the-breast
#14
Sahar Nozad, Christine E Sheehan, Laurie M Gay, Julia A Elvin, Jo-Anne Vergilio, James Suh, Shakti Ramkissoon, Alexa B Schrock, Kim M Hirshfield, Nadia Ali, Shridar Ganesan, Siraj M Ali, Vincent A Miller, Philip J Stephens, Jeffrey S Ross, Jon H Chung
PURPOSE: Malignant phyllodes tumors (MPT) are exceptionally rare, and the genomic drivers of these tumors are still being elucidated. We performed comprehensive genomic profiling (CGP) of MPT to identify genomic alterations that will inform approaches to targeted therapy for patients with MPT, including relapsed, refractory, and metastatic disease. METHODS: DNA was extracted from formalin-fixed, paraffin-embedded samples from 24 consecutive patient cases of MPT...
February 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28194954/gecko-inspired-nanotentacle-surface-enhanced-raman-spectroscopy-substrate-for-sampling-and-reliable-detection-of-pesticide-residues-in-fruits-and-vegetables
#15
Pan Wang, Long Wu, Zhicheng Lu, Qin Li, Wenmin Yin, Fan Ding, Heyou Han
Rapid sampling and multicomponent detection are crucial for monitoring of pesticide residues analysis. Here, a gecko-inspired nanotentacle surface-enhanced Raman spectroscopy (G-SERS) platform is proposed for the first time for the simultaneous detection of three kinds of pesticides via a simple and intuitive "press and peeled-off" approach. The G-SERS platform obtained from seeding deposition of silver nanoparticles (Ag NPs) on 3D PDMS nanotentacle array is flexible and free-standing. Compared with other substrates, this G-SERS substrate can simultaneously provide outstanding SERS activity (enhancement factor = 1...
February 6, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28170236/protonation-and-sulfido-versus-oxo-ligation-changes-at-the-molybdenum-cofactor-in-xanthine-dehydrogenase-xdh-variants-studied-by-x-ray-absorption-spectroscopy
#16
Stefan Reschke, Stefan Mebs, Kajsa G V Sigfridsson-Clauss, Ramona Kositzki, Silke Leimkühler, Michael Haumann
Enzymes of the xanthine oxidase family are among the best characterized mononuclear molybdenum enzymes. Open questions about their mechanism of transfer of an oxygen atom to the substrate remain. The enzymes share a molybdenum cofactor (Moco) with the metal ion binding a molybdopterin (MPT) molecule via its dithiolene function and terminal sulfur and oxygen groups. For xanthine dehydrogenase (XDH) from the bacterium Rhodobacter capsulatus, we used X-ray absorption spectroscopy to determine the Mo site structure, its changes in a pH range of 5-10, and the influence of amino acids (Glu730 and Gln179) close to Moco in wild-type (WT), Q179A, and E730A variants, complemented by enzyme kinetics and quantum chemical studies...
February 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28162777/assumptions-behind-scoring-source-versus-item-memory-effects-of-age-hippocampal-lesions-and-mild-memory-problems
#17
Elisa Cooper, Andrea Greve, Richard N Henson
Source monitoring paradigms have been used to separate: 1) the probability of recognising an item (Item memory) and 2) the probability of remembering the context in which that item was previously encountered (Source memory), conditional on it being recognised. Multinomial Processing Tree (MPT) models are an effective way to estimate these conditional probabilities. Moreover, MPTs make explicit the assumptions behind different ways to parameterise Item and Source memory. Using data from six independent groups across two different paradigms, we show that one would draw different conclusions about the effects of age, age-related memory problems and hippocampal lesions on Item and Source memory, depending on the use of: 1) standard accuracy calculation vs MPT analysis, and 2) two different MPT models...
January 12, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28153981/does-the-membrane-pacemaker-theory-of-metabolism-explain-the-size-dependence-of-metabolic-rate-in-marine-mussels
#18
Alexey Sukhotin, Natalia Fokina, Tatiana Ruokolainen, Christian Bock, Hans-Otto Pörtner, Gisela Lannig
According to the Membrane Pacemaker Theory of metabolism (MPT) allometric scaling of metabolic rate in animals is determined by the composition of cellular and mitochondrial membranes that changes with body size in a predictable manner. MPT has been elaborated from interspecific comparisons in mammals. It projects that the degree of unsaturation of membrane phospholipids decreases in larger organisms, thereby lowering ion permeability of the membranes and making cellular and thus whole animal metabolism more efficient...
February 2, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28133923/a-comparative-study-of-ex-vivo-skin-optical-clearing-using-two-photon-microscopy
#19
Anton Sdobnov, Maxim E Darvin, Juergen Lademann, Valery Tuchin
Multiphoton tomography (MPT) is a prospective tool for imaging the skin structure. Aiming to increase the probing depth, a comparative ex vivo study of optical clearing of porcine ear skin was performed by using two optical clearing agents (OCAs), i.e., glycerol and iohexol (Omnipaque(TM) ) at different concentrations, which exhibit different osmotic properties. The results show that a topical application of glycerol or Omnipaque(TM) solutions onto the skin for 60 min significantly improved the depth and contrast of the MPT signals...
January 30, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28120059/minipterional-craniotomy-for-treatment-of-unruptured-middle-cerebral-artery-aneurysms-a-single-center-comparative-analysis-with-standard-pterional-approach-as-regard-to-safety-and-efficacy-of-aneurysm-clipping-and-the-advantages-of-reconstruction
#20
Carmelo Lucio Sturiale, Giuseppe La Rocca, Alfredo Puca, Eduardo Fernandez, Massimiliano Visocchi, Enrico Marchese, Giovanni Sabatino, Alessio Albanese
Pterional craniotomy (PT) has long been the standard approach for the treatment of middle cerebral artery (MCA) aneurysms, even though it may cause temporalis muscle atrophy, facial nerve injury, and masticatory difficulties. Minipterional craniotomy (MPT) is an alternative approach that may provide the same surgical corridor, limiting the risk of postoperative esthetic and functional complications. From January 2011 to December 2014 we consecutively performed 68 craniotomies for surgical treatment of unruptured MCA aneuryms: 37 were standard PT and 31 were MPT...
2017: Acta Neurochirurgica. Supplement
keyword
keyword
87438
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"