keyword
https://read.qxmd.com/read/38662539/update-on-applications-of-endoscopic-cryotherapy-in-the-gastrointestinal-tract
#1
JOURNAL ARTICLE
Sarah Enslin, Vivek Kaul
PURPOSE OF REVIEW: Endoscopic cryotherapy has emerged as a minimally invasive procedure for targeted tissue ablation within the gastrointestinal tract. This review aims to provide a comprehensive overview of current clinical applications of EC with a review of the pertinent literature. RECENT FINDINGS: Endoscopic cryotherapy has demonstrated safety and efficacy for various gastrointestinal conditions. Recent studies have highlighted the efficacy of endoscopic cryotherapy, including both liquid nitrogen-based spray cryotherapy and the novel cryoballoon focal ablation system, in achieving complete eradication of dysplasia and neoplasia in Barrett's esophagus...
April 25, 2024: Current Opinion in Gastroenterology
https://read.qxmd.com/read/38661701/navigating-clinical-questions
#2
JOURNAL ARTICLE
Debra Barrett Graham
Lead with the problem, never the intervention.
May 1, 2024: American Journal of Nursing
https://read.qxmd.com/read/38660977/evaluation-of-patient-education-materials-from-large-language-artificial-intelligence-models-on-carpal-tunnel-release
#3
JOURNAL ARTICLE
Brett J Croen, Mohammed S Abdullah, Ellis Berns, Sarah Rapaport, Alexander K Hahn, Caitlin C Barrett, Andrew D Sobel
BACKGROUND: ChatGPT, an artificial intelligence technology, has the potential to be a useful patient aid, though the accuracy and appropriateness of its responses and recommendations on common hand surgical pathologies and procedures must be understood. Comparing the sources referenced and characteristics of responses from ChatGPT and an established search engine (Google) on carpal tunnel surgery will allow for an understanding of the utility of ChatGPT for patient education. METHODS: A Google search of "carpal tunnel release surgery" was performed and "frequently asked questions (FAQs)" were recorded with their answer and source...
April 25, 2024: Hand: Official Journal of the American Association for Hand Surgery
https://read.qxmd.com/read/38660654/esophageal-cancer-screening-early-detection-and-treatment-current-insights-and-future-directions
#4
REVIEW
Hong-Tao Qu, Qing Li, Liang Hao, Yan-Jing Ni, Wen-Yu Luan, Zhe Yang, Xiao-Dong Chen, Tong-Tong Zhang, Yan-Dong Miao, Fang Zhang
Esophageal cancer ranks among the most prevalent malignant tumors globally, primarily due to its highly aggressive nature and poor survival rates. According to the 2020 global cancer statistics, there were approximately 604000 new cases of esophageal cancer, resulting in 544000 deaths. The 5-year survival rate hovers around a mere 15%-25%. Notably, distinct variations exist in the risk factors associated with the two primary histological types, influencing their worldwide incidence and distribution. Squamous cell carcinoma displays a high incidence in specific regions, such as certain areas in China, where it meets the cost-effectiveness criteria for widespread endoscopy-based early diagnosis within the local population...
April 15, 2024: World Journal of Gastrointestinal Oncology
https://read.qxmd.com/read/38659862/the-role-of-prenatal-maternal-sex-steroid-hormones-in-weight-and-adiposity-at-birth-and-growth-trajectories-during-infancy
#5
Ying Meng, Loralei Thornburg, Caitlin Dreisbach, Charlotte Orzolek, Amber Kautz, Hannah Murphy, Zorimar Rivera- Núñez, Christina Wang, Richard Miller, Thomas O'Connor, Emily Barrett
Objective : Intrauterine factors can impact fetal and child growth and may underlie the developmental origins of childhood obesity. Sex steroid hormone exposure during pregnancy is a plausible target because of the impact on placental vascularization, nutrient transportation, bone growth, adipogenesis, and epigenetic modifications. In this study we assessed maternal sex steroid hormones in each trimester in relation to birthweight, neonatal adiposity, and infant growth trajectories, and evaluate sensitive windows of development...
April 10, 2024: Research Square
https://read.qxmd.com/read/38659791/investigative-power-of-genomic-informational-field-theory-gift-relative-to-gwas-for-genotype-phenotype-mapping
#6
Panagiota Kyratzi, Oswald Matika, Amey H Brassington, Clare E Connie, Juan Xu, David A Barrett, Richard D Emes, Alan L Archibald, Andras Paldi, Kevin D Sinclair, Jonathan Wattis, Cyril Rauch
Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using averages and variances from genotype-phenotype datasets. Averages and variances are legitimated upon creating distribution density functions obtained through the grouping of data into categories. However, as data from within a given category cannot be differentiated, the investigative power of such methodologies is limited...
April 16, 2024: bioRxiv
https://read.qxmd.com/read/38658761/probing-entanglement-in-a-2d-hard-core-bose-hubbard-lattice
#7
JOURNAL ARTICLE
Amir H Karamlou, Ilan T Rosen, Sarah E Muschinske, Cora N Barrett, Agustin Di Paolo, Leon Ding, Patrick M Harrington, Max Hays, Rabindra Das, David K Kim, Bethany M Niedzielski, Meghan Schuldt, Kyle Serniak, Mollie E Schwartz, Jonilyn L Yoder, Simon Gustavsson, Yariv Yanay, Jeffrey A Grover, William D Oliver
Entanglement and its propagation are central to understanding many physical properties of quantum systems1-3 . Notably, within closed quantum many-body systems, entanglement is believed to yield emergent thermodynamic behaviour4-7 . However, a universal understanding remains challenging owing to the non-integrability and computational intractability of most large-scale quantum systems. Quantum hardware platforms provide a means to study the formation and scaling of entanglement in interacting many-body systems8-14 ...
April 24, 2024: Nature
https://read.qxmd.com/read/38658746/phylogenomics-and-the-rise-of-the-angiosperms
#8
JOURNAL ARTICLE
Alexandre R Zuntini, Tom Carruthers, Olivier Maurin, Paul C Bailey, Kevin Leempoel, Grace E Brewer, Niroshini Epitawalage, Elaine Françoso, Berta Gallego-Paramo, Catherine McGinnie, Raquel Negrão, Shyamali R Roy, Lalita Simpson, Eduardo Toledo Romero, Vanessa M A Barber, Laura Botigué, James J Clarkson, Robyn S Cowan, Steven Dodsworth, Matthew G Johnson, Jan T Kim, Lisa Pokorny, Norman J Wickett, Guilherme M Antar, Lucinda DeBolt, Karime Gutierrez, Kasper P Hendriks, Alina Hoewener, Ai-Qun Hu, Elizabeth M Joyce, Izai A B S Kikuchi, Isabel Larridon, Drew A Larson, Elton John de Lírio, Jing-Xia Liu, Panagiota Malakasi, Natalia A S Przelomska, Toral Shah, Juan Viruel, Theodore R Allnutt, Gabriel K Ameka, Rose L Andrew, Marc S Appelhans, Montserrat Arista, María Jesús Ariza, Juan Arroyo, Watchara Arthan, Julien B Bachelier, C Donovan Bailey, Helen F Barnes, Matthew D Barrett, Russell L Barrett, Randall J Bayer, Michael J Bayly, Ed Biffin, Nicky Biggs, Joanne L Birch, Diego Bogarín, Renata Borosova, Alexander M C Bowles, Peter C Boyce, Gemma L C Bramley, Marie Briggs, Linda Broadhurst, Gillian K Brown, Jeremy J Bruhl, Anne Bruneau, Sven Buerki, Edie Burns, Margaret Byrne, Stuart Cable, Ainsley Calladine, Martin W Callmander, Ángela Cano, David J Cantrill, Warren M Cardinal-McTeague, Mónica M Carlsen, Abigail J A Carruthers, Alejandra de Castro Mateo, Mark W Chase, Lars W Chatrou, Martin Cheek, Shilin Chen, Maarten J M Christenhusz, Pascal-Antoine Christin, Mark A Clements, Skye C Coffey, John G Conran, Xavier Cornejo, Thomas L P Couvreur, Ian D Cowie, Laszlo Csiba, Iain Darbyshire, Gerrit Davidse, Nina M J Davies, Aaron P Davis, Kor-Jent van Dijk, Stephen R Downie, Marco F Duretto, Melvin R Duvall, Sara L Edwards, Urs Eggli, Roy H J Erkens, Marcial Escudero, Manuel de la Estrella, Federico Fabriani, Michael F Fay, Paola de L Ferreira, Sarah Z Ficinski, Rachael M Fowler, Sue Frisby, Lin Fu, Tim Fulcher, Mercè Galbany-Casals, Elliot M Gardner, Dmitry A German, Augusto Giaretta, Marc Gibernau, Lynn J Gillespie, Cynthia C González, David J Goyder, Sean W Graham, Aurélie Grall, Laura Green, Bee F Gunn, Diego G Gutiérrez, Jan Hackel, Thomas Haevermans, Anna Haigh, Jocelyn C Hall, Tony Hall, Melissa J Harrison, Sebastian A Hatt, Oriane Hidalgo, Trevor R Hodkinson, Gareth D Holmes, Helen C F Hopkins, Christopher J Jackson, Shelley A James, Richard W Jobson, Gudrun Kadereit, Imalka M Kahandawala, Kent Kainulainen, Masahiro Kato, Elizabeth A Kellogg, Graham J King, Beata Klejevskaja, Bente B Klitgaard, Ronell R Klopper, Sandra Knapp, Marcus A Koch, James H Leebens-Mack, Frederic Lens, Christine J Leon, Étienne Léveillé-Bourret, Gwilym P Lewis, De-Zhu Li, Lan Li, Sigrid Liede-Schumann, Tatyana Livshultz, David Lorence, Meng Lu, Patricia Lu-Irving, Jaquelini Luber, Eve J Lucas, Manuel Luján, Mabel Lum, Terry D Macfarlane, Carlos Magdalena, Vidal F Mansano, Lizo E Masters, Simon J Mayo, Kristina McColl, Angela J McDonnell, Andrew E McDougall, Todd G B McLay, Hannah McPherson, Rosa I Meneses, Vincent S F T Merckx, Fabián A Michelangeli, John D Mitchell, Alexandre K Monro, Michael J Moore, Taryn L Mueller, Klaus Mummenhoff, Jérôme Munzinger, Priscilla Muriel, Daniel J Murphy, Katharina Nargar, Lars Nauheimer, Francis J Nge, Reto Nyffeler, Andrés Orejuela, Edgardo M Ortiz, Luis Palazzesi, Ariane Luna Peixoto, Susan K Pell, Jaume Pellicer, Darin S Penneys, Oscar A Perez-Escobar, Claes Persson, Marc Pignal, Yohan Pillon, José R Pirani, Gregory M Plunkett, Robyn F Powell, Ghillean T Prance, Carmen Puglisi, Ming Qin, Richard K Rabeler, Paul E J Rees, Matthew Renner, Eric H Roalson, Michele Rodda, Zachary S Rogers, Saba Rokni, Rolf Rutishauser, Miguel F de Salas, Hanno Schaefer, Rowan J Schley, Alexander Schmidt-Lebuhn, Alison Shapcott, Ihsan Al-Shehbaz, Kelly A Shepherd, Mark P Simmons, André O Simões, Ana Rita G Simões, Michelle Siros, Eric C Smidt, James F Smith, Neil Snow, Douglas E Soltis, Pamela S Soltis, Robert J Soreng, Cynthia A Sothers, Julian R Starr, Peter F Stevens, Shannon C K Straub, Lena Struwe, Jennifer M Taylor, Ian R H Telford, Andrew H Thornhill, Ifeanna Tooth, Anna Trias-Blasi, Frank Udovicic, Timothy M A Utteridge, Jose C Del Valle, G Anthony Verboom, Helen P Vonow, Maria S Vorontsova, Jurriaan M de Vos, Noor Al-Wattar, Michelle Waycott, Cassiano A D Welker, Adam J White, Jan J Wieringa, Luis T Williamson, Trevor C Wilson, Sin Yeng Wong, Lisa A Woods, Roseina Woods, Stuart Worboys, Martin Xanthos, Ya Yang, Yu-Xiao Zhang, Meng-Yuan Zhou, Sue Zmarzty, Fernando O Zuloaga, Alexandre Antonelli, Sidonie Bellot, Darren M Crayn, Olwen M Grace, Paul J Kersey, Ilia J Leitch, Hervé Sauquet, Stephen A Smith, Wolf L Eiserhardt, Félix Forest, William J Baker
Angiosperms are the cornerstone of most terrestrial ecosystems and human livelihoods1,2 . A robust understanding of angiosperm evolution is required to explain their rise to ecological dominance. So far, the angiosperm tree of life has been determined primarily by means of analyses of the plastid genome3,4 . Many studies have drawn on this foundational work, such as classification and first insights into angiosperm diversification since their Mesozoic origins5-7 . However, the limited and biased sampling of both taxa and genomes undermines confidence in the tree and its implications...
April 24, 2024: Nature
https://read.qxmd.com/read/38658491/predictability-of-existing-iol-formulas-after-cataract-surgery-in-patients-with-a-previous-history-of-radial-keratotomy-a-retrospective-cohort-study-and-literature-review
#9
JOURNAL ARTICLE
Majid Moshirfar, Ronald A Sperry, Amal W Altaf, Isabella M Stoakes, Phillip C Hoopes
INTRODUCTION: This study aims to evaluate the accuracy of 12 different intraocular lens (IOL) power calculation formulas for post-radial keratotomy (RK) eyes. The investigation utilizes recent advances in topography/tomography devices and artificial intelligence (AI)-based calculators, comparing the results to those reported in current literature to assess the efficacy and predictability of IOL calculations for this patient group. METHODS: In this retrospective study, 37 eyes from 24 individuals with a history of RK who underwent cataract surgery at Hoopes Vision Center were analyzed...
April 25, 2024: Ophthalmology and Therapy
https://read.qxmd.com/read/38656810/advancements-in-the-application-of-uterine-ultrasound-elastography
#10
REVIEW
Francesca Barrett, Stephanie Willson, Marie Werner
PURPOSE OF REVIEW: This article reviews recent advances in ultrasound elastography in diagnosing and evaluating the normal nongravid uterus and the infertile uterus in the gynecologic patient. RECENT FINDINGS: Focusing on the most recent primary literature, studies have demonstrated new findings among a breadth of gynecologic clinical settings. Studies in the nongravid uterus have found that menopausal status, age, and menstrual phase have not been associated with changes in uterine tissue stiffness...
June 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38656709/biparametric-mri-in-prostate-cancer-during-active-surveillance-is-it-safe
#11
REVIEW
Iztok Caglic, Nikita Sushentsev, Tom Syer, Kang-Lung Lee, Tristan Barrett
Active surveillance (AS) is the preferred option for patients presenting with low-intermediate-risk prostate cancer. MRI now plays a crucial role for baseline assessment and ongoing monitoring of AS. The Prostate Cancer Radiological Estimation of Change in Sequential Evaluation (PRECISE) recommendations aid radiological assessment of progression; however, current guidelines do not advise on MRI protocols nor on frequency. Biparametric (bp) imaging without contrast administration offers advantages such as reduced costs and increased throughput, with similar outcomes to multiparametric (mp) MRI shown in the biopsy naïve setting...
April 24, 2024: European Radiology
https://read.qxmd.com/read/38654541/risk-of-intrapartum-cesarean-delivery-in-twin-pregnancies-a-retrospective-cohort-study
#12
JOURNAL ARTICLE
Moshe Barg, Ben Melamed, Amir Aviram, Elad Mei-Dan, Jon Barrett, Nir Melamed
OBJECTIVE: To compare the risk of intrapartum cesarean delivery (CD) between patients with twin and singleton pregnancies undergoing a trial of labor and identify risk factors for intrapartum CD in twin pregnancies. METHODS: The present study was a retrospective cohort study of patients with a twin or singleton pregnancy who underwent a trial of labor at ≥340/7 weeks in a single center (2015-2022). The primary outcome was the rate of intrapartum CD. In twin pregnancies, this outcome was limited to CD of both twins...
April 23, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38654449/the-intricate-physiology-of-veno-venous-extracorporeal-membrane-oxygenation-an-overview-for-clinicians
#13
REVIEW
Emilia Tomarchio, Francesca Momigliano, Lorenzo Giosa, Patrick Duncan Collins, Nicholas A Barrett, Luigi Camporota
During veno-venous extracorporeal membrane oxygenation (V-V ECMO), blood is drained from the central venous circulation to be oxygenated and decarbonated by an artificial lung. It is then reinfused into the right heart and pulmonary circulation where further gas-exchange occurs. Each of these steps is characterized by a peculiar physiology that this manuscript analyses, with the aim of providing bedside tools for clinical care: we begin by describing the factors that affect the efficiency of blood drainage, such as patient and cannulae position, fluid status, cardiac output and ventilatory strategies...
April 2024: Perfusion
https://read.qxmd.com/read/38654044/genomic-landscape-of-diploid-and-aneuploid-microsatellite-stable-early-onset-colorectal-cancer
#14
JOURNAL ARTICLE
Yumei Zhou, Xianfeng Chen, Jun Chen, Conner D Kendrick, Ramesh K Ramanathan, Rondell P Graham, Kimberlee F Kossick, Lisa A Boardman, Michael T Barrett
Although colorectal cancer (CRC) remains the second leading cause of cancer-related death in the United States, the overall incidence and mortality from the disease have declined in recent decades. In contrast, there has been a steady increase in the incidence of CRC in individuals under 50 years of age. Hereditary syndromes contribute disproportionately to early onset CRC (EOCRC). These include microsatellite instability high (MSI+) tumors arising in patients with Lynch Syndrome. However, most EOCRCs are not associated with familial syndromes or MSI+ genotypes...
April 23, 2024: Scientific Reports
https://read.qxmd.com/read/38653809/aligning-front-of-pack-labelling-with-dietary-guidelines-including-whole-grains-in-the-health-star-rating
#15
JOURNAL ARTICLE
Caitlin Byron, Katrina R Kissock, Eden M Barrett, Eleanor J Beck
PURPOSE: Front-of-pack labelling systems, such as the Health Star Rating (HSR), aim to aid healthy consumer dietary choices and complement national dietary guidelines. Dietary guidelines aim to be holistic by extending beyond the individual nutrients of food, including other food components that indicate diet quality, including whole grains. We aimed to test the feasibility of including whole grains in the HSR algorithm, to better inform dietary guidance in Australia coherent with existing dietary guidelines...
April 23, 2024: European Journal of Nutrition
https://read.qxmd.com/read/38652931/outcome-of-tonsillotomy-in-children-with-obstructive-sleep-disordered-breathing
#16
JOURNAL ARTICLE
Tina Kissow Lildal, An Boudewyns, Konstantinos Kamperis, Søren Rittig, Jannik B Bertelsen, Jonas Holm, Thomas Qvist Barrett, Jakob Korsholm, Ali Abood, Therese Ovesen
OBJECTIVE/BACKGROUND: Most children treated for obstructive sleep disordered breathing (oSDB) are not systematically assessed by polysomnography (PSG) nor by structuredsymptom quantification before surgical treatment. The main objective of this study wasto investigate the effect of adeno-tonsillotomy (ATO) on symptom burden and PSGparameters. METHODS: Children aged 2-10 years with oSDB were selected for ATO based uponclinical findings according to current standards of care in Denmark...
April 15, 2024: Sleep Medicine
https://read.qxmd.com/read/38651575/left-ventricular-unloading-in-patients-supported-with-veno-arterial-extra-corporeal-membrane-oxygenation-an-international-euroelso-survey
#17
JOURNAL ARTICLE
Saad M Ezad, Matthew Ryan, Nicholas Barrett, Luigi Camporota, Justyna Swol, Marta V Antonini, Dirk W Donker, Federico Pappalardo, Navin K Kapur, Louise Rose, Divaka Perera
INTRODUCTION: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) improves end-organ perfusion in cardiogenic shock but may increase afterload, which can limit cardiac recovery. Left ventricular (LV) unloading strategies may aid cardiac recovery and prevent complications of increased afterload. However, there is no consensus on when and which unloading strategy should be used. METHODS: An online survey was distributed worldwide via the EuroELSO newsletter mailing list to describe contemporary international practice and evaluate heterogeneity in strategies for LV unloading...
April 2024: Perfusion
https://read.qxmd.com/read/38648876/serum-levels-of-hydroxylated-metabolites-of-arachidonic-acid-cross-sectionally-and-longitudinally-predict-knee-pain-progression-an-observational-cohort-study
#18
JOURNAL ARTICLE
James Turnbull, Rakesh R Jha, Peter R W Gowler, Rose Ferrands-Bentley, Dong-Hyun Kim, David A Barrett, Aliya Sarmanova, Gwen S Fernandes, Michael Doherty, Weiya Zhang, David A Walsh, Ana M Valdes, Victoria Chapman
OBJECTIVE: To examine associations between serum oxylipins, which regulate tissue repair and pain signalling, and knee pain/radiographic osteoarthritis (OA) at baseline and knee pain at 3 year follow-up. METHOD: Baseline, and 3 year follow-up, knee pain phenotypes were assessed from 154 participants in the Knee Pain in the Community Cohort (KPIC) study. Serum and radiographic Kellgren and Lawrence (KL) and Nottingham line drawing atlas (NLDA) OA scores were collected at baseline...
April 20, 2024: Osteoarthritis and Cartilage
https://read.qxmd.com/read/38648857/aapm-task-group-334-a-guidance-document-to-using-radiotherapy-immobilization-devices-and-accessories-in-an-mr-environment
#19
JOURNAL ARTICLE
Maritza A Hobson, Yanle Hu, Barrett Caldwell, Gil'ad N Cohen, Carri Glide-Hurst, Long Huang, Paul D Jackson, Sunyoung Jang, Ulrich Langner, Hannah J Lee, Ives R Levesque, Sreeram Narayanan, Justin C Park, John Steffen, Q Jackie Wu, Yong Zhou
Use of magnetic resonance (MR) imaging in radiation therapy has increased substantially in recent years as more radiotherapy centers are having MR simulators installed, requesting more time on clinical diagnostic MR systems, or even treating with combination MR linear accelerator (MR-linac) systems. With this increased use, to ensure the most accurate integration of images into radiotherapy (RT), RT immobilization devices and accessories must be able to be used safely in the MR environment and produce minimal perturbations...
April 22, 2024: Medical Physics
https://read.qxmd.com/read/38645042/affective-symptoms-in-pregnancy-are-associated-with-the-vaginal-microbiome
#20
Kristin Scheible, Robert Beblavy, Michael B Sohn, Xing Qui, Ann L Gill, Janiret Narvaez-Miranda, Jessica Brunner, Richard K Miller, Emily S Barrett, Tom G O'Connor, Steven R Gill
UNLABELLED: Composition of the vaginal microbiome in pregnancy is associated with adverse maternal, obstetric, and child health outcomes. Identifying the sources of individual differences in the vaginal microbiome is therefore of considerable clinical and public health interest. The current study tested the hypothesis that vaginal microbiome composition during pregnancy is associated with an individual's experience of affective symptoms and stress exposure. Data were based on a prospective longitudinal study of a diverse and medically healthy community sample of 275 mother-infant pairs...
April 12, 2024: bioRxiv
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