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https://www.readbyqxmd.com/read/28437755/an-in-vitro-study-of-cartilage-meniscus-tribology-to-understand-the-changes-caused-by-a-meniscus-implant
#1
Sara Ehsani Majd, Aditya Iman Rizqy, Hans J Kaper, Tannin A Schmidt, Roel Kuijer, Prashant K Sharma
Active lifestyles increase the risk of meniscal injury. A permanent meniscus implant of polycarbonate urethane (PCU) is a promising treatment to postpone/prevent total knee arthroplasty. Study of the changes in articular cartilage tribology in the presence of PCU is essential in developing the optimum meniscus implant. Therefore, a cartilage-meniscus reciprocating, sliding model was developed in vitro, mimicking the stance and swing phases of the gait cycle. The meniscus was further replaced with PCU and surface-modified PCUs (with C18 chains, mono-functional polydimethylsiloxane groups and mono-functional polytetrafluoroethylene groups) to study the changes...
April 18, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28437501/pronator-teres-myotendinous-tear
#2
Usama Qayyum, Diego Villacis, Charles M Jobin
Pronator teres muscle strain is a rare sporting injury reported thus far only in cricket and golf players. The injury appears to occur when the sporting club or racket strikes the ground during a forceful swing and causes the elbow to experience an eccentric force during resisted elbow flexion and pronation. On initial presentation, this injury can be mistaken for injury to the medial ulnar collateral ligament, or exacerbation of medial epicondylitis. On examination, bruising and tenderness distal to the elbow over the course of the pronator teres are often present...
March 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28433867/validity-and-repeatability-of-inertial-measurement-units-for-measuring-gait-parameters
#3
Edward P Washabaugh, Tarun Kalyanaraman, Peter G Adamczyk, Edward S Claflin, Chandramouli Krishnan
Inertial measurement units (IMUs) are small wearable sensors that have tremendous potential to be applied to clinical gait analysis. They allow objective evaluation of gait and movement disorders outside the clinic and research laboratory, and permit evaluation on large numbers of steps. However, repeatability and validity data of these systems are sparse for gait metrics. The purpose of this study was to determine the validity and between-day repeatability of spatiotemporal metrics (gait speed, stance percent, swing percent, gait cycle time, stride length, cadence, and step duration) as measured with the APDM Opal IMUs and Mobility Lab system...
April 12, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28433389/comparison-of-methodologies-to-assess-muscle-co-contraction-during-gait
#4
H Souissi, R Zory, J Bredin, P Gerus
The aim of this study was to compare co-contraction index (CCI) computed from muscle moments to different co-activation indexes (Co-Act) derived from EMG data at the ankle and the knee joint during gait. An EMG-driven model was used to estimate muscle moments during over-ground walking gait at a self-selected velocity from twelve healthy subjects. The CCI calculated from muscle moments was compared with three Co-Acts estimated from the normalized EMG data. The co-activation methods produced lower values than the CCI during the first double-support and the swing phase at the ankle joint and during the stance phase at the knee joint...
April 9, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28432328/tactile-flow-overides-other-cues-to-self-motion
#5
Laurence R Harris, Kenzo Sakurai, William H A Beaudot
Vestibular-somatosensory interactions are pervasive in the brain but it remains unclear why. Here we explore the contribution of tactile flow to processing self-motion. We assessed two aspects of self-motion: timing and speed. Participants sat on an oscillating swing and either kept their hands on their laps or rested them lightly on an earth-stationary surface. They viewed a grating oscillating at the same frequency as their motion and judged its phase or, in a separate experiment, its speed relative to their perceived motion...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28430147/suitability-of-strain-gage-sensors-for-integration-into-smart-sport-equipment-a-golf-club-example
#6
Anton Umek, Yuan Zhang, Sašo Tomažič, Anton Kos
Wearable devices and smart sport equipment are being increasingly used in amateur and professional sports. Smart sport equipment employs various sensors for detecting its state and actions. The correct choice of the most appropriate sensor(s) is of paramount importance for efficient and successful operation of sport equipment. When integrated into the sport equipment, ideal sensors are unobstructive, and do not change the functionality of the equipment. The article focuses on experiments for identification and selection of sensors that are suitable for the integration into a golf club with the final goal of their use in real time biofeedback applications...
April 21, 2017: Sensors
https://www.readbyqxmd.com/read/28428034/near-anatomical-correction-using-a-ct-guided-technique-of-a-forearm-malunion-in-a-15-year-old-girl-a-case-report-including-surgical-technique
#7
Ralph M Jeuken, Roel P Hendrickx, Martijn G Schotanus, Edwin J Jansen
BACKGROUND: In this case report we describe a left-arm both-bone forearm fracture in a 15-year old girl who fell off of a swing. Conservative treatment with an above-elbow cast failed,resulting in a malunion with functional impairment. The pro- and supination were 90/0/10, respectively. The patient complained of difficulties performing daily activities. For this pediatric case a corrective osteotomy was proposed using a CT-guided technique aiming for maximum anatomical and functional outcome...
April 17, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28427694/gait-pattern-in-patients-with-different-multiple-sclerosis-phenotypes
#8
Irena Dujmovic, Sasa Radovanovic, Vanja Martinovic, Jelena Dackovic, Gorica Maric, Sarlota Mesaros, Tatjana Pekmezovic, Vladimir Kostic, Jelena Drulovic
BACKGROUND: Gait pattern is frequently impaired in multiple sclerosis (MS), however gait characteristics in patients with different MS phenotypes have not been fully elucidated. METHODS: We analyzed spatio-temporal gait pattern characteristics in patients with relapsing-remitting (RR, n=52) and primary-progressive (PP, n=18) MS in comparison with age-matched healthy controls (HC, n=40). All subjects performed a standardized simple walking task, a dual motor- motor task, a dual motor-mental task, and a triple combined motor-mental task at a GAITRite electronic walkway of 5...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28424473/highly-gate-tuneable-rashba-spin-orbit-interaction-in-a-gate-all-around-inas-nanowire-metal-oxide-semiconductor-field-effect-transistor
#9
K Takase, Y Ashikawa, G Zhang, K Tateno, S Sasaki
III-V semiconductors have been intensively studied with the goal of realizing metal-oxide-semiconductor field-effect transistors (MOSFETs) with high mobility, a high on-off ratio, and low power consumption as next-generation transistors designed to replace current Si technology. Of these semiconductors, a narrow band-gap semiconductor InAs has strong Rashba spin-orbit interaction, thus making it advantageous in terms of both high field-effect transistor (FET) performance and efficient spin control. Here we report a high-performance InAs nanowire MOSFET with a gate-all-around (GAA) structure, where we simultaneously control the spin precession using the Rashba interaction...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28416900/measurement-errors-when-estimating-the-vertical-jump-height-with-flight-time-using-photocell-devices-the-example-of-optojump
#10
A Attia, W Dhahbi, A Chaouachi, J Padulo, D P Wong, K Chamari
Common methods to estimate vertical jump height (VJH) are based on the measurements of flight time (FT) or vertical reaction force. This study aimed to assess the measurement errors when estimating the VJH with flight time using photocell devices in comparison with the gold standard jump height measured by a force plate (FP). The second purpose was to determine the intrinsic reliability of the Optojump photoelectric cells in estimating VJH. For this aim, 20 subjects (age: 22.50±1.24 years) performed maximal vertical jumps in three modalities in randomized order: the squat jump (SJ), counter-movement jump (CMJ), and CMJ with arm swing (CMJarm)...
March 2017: Biology of Sport
https://www.readbyqxmd.com/read/28416148/alterations-in-autonomic-cerebrovascular-control-after-spinal-cord-injury
#11
Dong-Il Kim, Can Ozan Tan
Among chronic cardiovascular and metabolic sequelae of spinal cord injury (SCI) is an up-to four-fold increase in the risk of ischemic and hemorrhagic stroke, suggesting that individuals with SCI cannot maintain stable cerebral perfusion. In able-bodied individuals, the cerebral vasculature is able to regulate cerebral perfusion in response to swings in arterial pressure (cerebral autoregulation), blood gases (cerebral vasoreactivity), and neural metabolic demand (neurovascular coupling). This ability depends, at least partly, on intact autonomic function, but high thoracic and cervical spinal cord injuries result in disruption of sympathetic and parasympathetic cerebrovascular control...
April 4, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28415050/free-radicals-and-polyphenols-the-redox-chemistry-of-neurodegenerative-diseases
#12
REVIEW
Sonia Losada-Barreiro, Carlos Bravo-Díaz
The oxidation of bioorganic materials by air and, particularly, the oxidative stress involved in the cell loss and other pathologies associated with neurodegenerative diseases (NDs) are of enormous social and economic importance. NDs generally involve free radical reactions, beginning with the formation of an initiating radical by some redox, thermal or photochemical process, causing nucleic acid, protein and lipid oxidations and the production of harmful oxidative products. Physically, persons afflicted by NDs suffer progressive loss of memory and thinking ability, mood swings, personality changes, and loss of independence...
March 29, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28414156/modeling-of-interactions-between-functional-domains-of-aldh1l1
#13
David A Horita, Sergey A Krupenko
ALDH1L1, a member of the aldehyde dehydrogenase superfamily of enzymes, catalyzes the conversion of 10-formyltetrahydrofolate to tetrahydrofolate and CO2. The enzyme is a tetramer of identical subunits, with each subunit consisting of three functional domains that originated from unrelated genes. The N- and C-terminal domains are catalytic, while the intermediate domain transfers the reaction intermediate from the N- to the C-terminal domain. The intermediate domain is an acyl carrier protein, possessing the covalently attached 4'-phosphopantetheine (4-PP) prosthetic group...
April 14, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28413690/a-dynamic-model-for-gps-based-attitude-determination-and-testing-using-a-serial-robotic-manipulator
#14
Almat Raskaliyev, Sarosh Patel, Tarek Sobh
A computational algorithm is developed for estimating accurately the attitude of a robotic arm which moves along a predetermined path. This algorithm requires preliminary input data obtained in the static mode to yield phase observables for the precise, 3-axis attitude determination of a swinging manipulator in the dynamic mode. Measurements are recorded simultaneously by three GPS L1 receivers and then processed in several steps to accomplish this task. First, artkconv batch executable converts GPS receiver readings into RINEX format to generate GPS observables and ephemeris for multiple satellites...
July 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28410536/the-influence-of-ball-swing-on-the-timing-and-coordination-of-a-natural-interceptive-task
#15
Vishnu Sarpeshkar, David L Mann, Wayne Spratford, Bruce Abernethy
Successful interception relies on the use of perceptual information to accurately guide an efficient movement strategy that allows performers to be placed at the right place at the right time. Although previous studies have highlighted the differences in the timing and coordination of movement that underpin interceptive expertise, very little is known about how these movement patterns are adapted when intercepting targets that follow a curvilinear flight-path. The aim of this study was to examine how curvilinear ball-trajectories influence movement patterns when intercepting a fast-moving target...
April 11, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28409952/nonsymmetric-interactions-trigger-collective-swings-in-globally-ordered-systems
#16
Andrea Cavagna, Irene Giardina, Asja Jelic, Stefania Melillo, Leonardo Parisi, Edmondo Silvestri, Massimiliano Viale
Many systems in nature, from ferromagnets to flocks of birds, exhibit ordering phenomena on the large scale. In condensed matter systems, order is statistically robust for large enough dimensions, with relative fluctuations due to noise vanishing with system size. Several biological systems, however, are less stable and spontaneously change their global state on relatively short time scales. Here we show that there are two crucial ingredients in these systems that enhance the effect of noise, leading to collective changes of state on finite time scales and off-equilibrium behavior: the nonsymmetric nature of interactions between individuals, and the presence of local heterogeneities in the topology of the network...
March 31, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28408157/microsoft-kinect-can-distinguish-differences-in-over-ground-gait-between-older-persons-with-and-without-parkinson-s-disease
#17
Moataz Eltoukhy, Christopher Kuenze, Jeonghoon Oh, Marco Jacopetti, Savannah Wooten, Joseph Signorile
Gait patterns differ between healthy elders and those with Parkinson's disease (PD). A simple, low-cost clinical tool that can evaluate kinematic differences between these populations would be invaluable diagnostically; since gait analysis in a clinical setting is impractical due to cost and technical expertise. This study investigated the between group differences between the Kinect and a 3D movement analysis system (BTS) and reported validity and reliability of the Kinect v2 sensor for gait analysis. Nineteen subjects participated, eleven without (C) and eight with PD (PD)...
April 10, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28407505/a-randomized-controlled-trial-on-providing-ankle-foot-orthoses-in-patients-with-sub-acute-stroke-short-term-kinematic-and-spatiotemporal-effects-and-effects-of-timing
#18
Corien D M Nikamp, Marte S H Hobbelink, Job van der Palen, Hermie J Hermens, Johan S Rietman, Jaap H Buurke
Initial walking function is often limited after stroke, and regaining walking ability is an important goal in rehabilitation. Various compensatory movement strategies to ensure sufficient foot-clearance are reported. Ankle-foot orthoses (AFOs) are often prescribed to improve foot-clearance and may influence these strategies. However, research studying effects of actual AFO-provision early after stroke is limited. We conducted an explorative randomized controlled trial and aimed to study the short-term effects of AFO-provision on kinematic and spatiotemporal parameters in patients early after stroke...
March 30, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28401818/-analysing-gait-in-the-gp-s-consulting-room
#19
T van Meulenbroek, I P J Huijnen, G H H Meys, G M Rommers
Gait disorders are often seen in the general practitioner (GP)'s consulting room. Orthopaedic or neurological problems may lead to abnormalities in gait. A careful analysis is important to advice or refer the patient for additional diagnostics or treatment. Basic gait analysis can be performed on any patient by applying a systematic stepwise observation. This is illustrated here by three case reports. This observation starts by looking at parameters such as walking speed, safety, efficiency etc. Analysis of biomechanical pattern such as step frequency, stride length and a detailed analysis of the different joint movements during the stance and swing phase can subsequently be performed...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28401186/caspase-9-swings-both-ways-in-the-apoptosome
#20
Chu-Chiao Wu, Shawn B Bratton
For nearly 2 decades, investigators have debated whether cysteinyl-aspartate-specific protease 9 (caspase-9) is activated within the apoptotic protease-activating factor 1 (Apaf-1) apoptosome through proximity-induced homodimerization or through formation of a holoenzyme. Recently, we have demonstrated that caspase-9 forms (and likely transitions between) both caspase-9 homo- and Apaf-1:caspase-9 heterodimers, each of which plays unique roles in the recruitment and activation of caspase-9.
2017: Molecular & Cellular Oncology
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