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arteritis and TRAPS

Raúl Iglesias, José M García-Estévez, César Ayres, Antonio Acuña, Adolfo Cordero-Rivera
The importance of disease-mediated invasions and the role of parasite spillover as a substantial threat to the conservation of global biodiversity are now well known. Although competition between invasive sliders Trachemys scripta elegans and indigenous European turtles has been extensively studied, the impact of this invasive species on diseases affecting native populations is poorly known. During winter 2012-2013 an unusual event was detected in a population of Emys orbicularis (Linnaeus, 1758) inhabiting a pond system in Galicia (NW Spain)...
February 10, 2015: Diseases of Aquatic Organisms
Christian A Bowers, Dany Saad, Daniel O Clegg, Perry Ng, Frederic Clayton, Souha Haydoura, Richard H Schmidt
OBJECT: Tumor necrosis factor (TNF)-α inhibitors are effective at treating certain inflammatory and autoimmune disorders. They are generally safe; potential adverse events include infections (bacterial, fungal, and viral), congestive heart failure exacerbations, and the potential for demyelinating diseases and possibly certain malignancies. We present the first documented case of fungal internal carotid artery (ICA) mycotic aneurysm in a patient being treated with a TNF-α inhibitor...
May 2015: Journal of Neurological Surgery. Part A, Central European Neurosurgery
M Bouyon, F Blanc, L Ballonzoli, M Fleury, C Zaenker, C Speeg-Schatz, J de Seze
INTRODUCTION: Meningiomas are benign primary meningeal tumors. Their diagnosis may be incidental or in response to a work-up for neurological or ophthalmological symptoms. PATIENTS AND METHODS: The clinical course of five patients with ophthalmological symptoms leading to the diagnosis of meningioma is described. RESULTS: The case reports consist of five women (48 to 54 years old - mean 52 years at the onset of symptoms), all suffering from a progressive unilateral decrease in visual acuity with a normal initial fundus examination and ipsilateral visual field changes...
March 2013: Journal Français D'ophtalmologie
L Macovei, Gabriela Omete, Cătălina Arsenescu-Georgescu
Sometimes, acute aortic dissection diagnosis, a significant cardiological and surgical emergency, is particularly difficult. Therefore, Takayasu arteritis associated dissection fold may be a real diagnostic "trap", in spite of all modern exploratory techniques.
January 2011: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Haruki Yamakawa, Yasuhiko Kaku, Shin-ichi Yoshimura, Akio Ohkuma, Noboru Sakai
BACKGROUND: Dissecting aneurysm of the posterior inferior cerebellar artery (PICA) uninvolved with the vertebral artery is rare. The exact pathohistological diagnosis might result in 'unknown' because the underlying pathoanatomical features are, for a variety of reasons, not always identified. CASE DESCRIPTION: We report herein two cases of dissecting aneurysm harbored in different segments of the distal posterior inferior cerebellar artery. In our cases, after trapping the PICA at both just proximal and distal to the aneurysm, the abnormal portion was successfully resected with/without an end-to-end anastomosis...
February 2005: Clinical Neurology and Neurosurgery
Hayato Funiu, Yasuaki Kokubo, Rei Kondo, Makoto Saino, Masato Ohki, Takamasa Kayama, Hiroyuki Orita, Shigeki Hirooka
We describe here successful surgical treatment of a rare case of a rapidly enlarged aneurysm due to Takayasu's arteritis. A 22-year-old woman presented with a 1-month history of hoarseness and left neck pain. Contrast-enhanced computerized tomography showed an unruptured partially thrombosed aneurysm, and angiography revealed a large aneurysm of the common carotid artery. After hospitalization, the symptoms, interestingly, resolved spontaneously. While angiography at 2 weeks after admission showed the aneurysm to have reduced in size, 2 months later it showed the left common carotid artery aneurysm to be substantially enlarged in size and aneurysmal formation of the right external carotid artery...
November 2004: Nō to Shinkei, Brain and Nerve
Wei Ma Krupa, Misha Dewan, Myung-Shin Jeon, Paul J Kurtin, Brian R Younge, Jörg J Goronzy, Cornelia M Weyand
Immature dendritic cells (DCs) are scattered throughout peripheral tissues and act as sentinels that sample the antigenic environment. After activation, they modify their chemokine receptor profile and migrate toward lymphoid tissues. On arrival, they have matured into chemokine-producing DCs that express co-stimulatory molecules and can prime naive T cells. Normal temporal arteries contain immature DCs that are located at the media-adventitia border. In temporal arteries affected by giant cell arteritis, DCs are highly enriched and activated and have matured into fully differentiated cells producing the chemokines, CCL18, CCL19, and CCL21...
November 2002: American Journal of Pathology
M Pineda Marfa
INTRODUCTION: The rheumatic disorders and vasculites are inflammatory processes affecting connective tissue in different organs. The inflamed cells liberate destructive enzymes which harm tissues, producing IgE, IgM, IgG antibodies and autoimmune complexes. OBJECTIVE: To review the current classification of these conditions and describe the commonest neurological complications in children. Infantile systemic lupus erythematosus is the commonest; it affects the dermis, joints, blood vessels, heart, kidney and brain...
August 1, 2002: Revista de Neurologia
Jun C Takahashi, Nobuyuki Sakai, Koji Iihara, Hideki Sakai, Toshio Higashi, Shuji Kogure, Ayumi Taniguchi, Hatsue I Ueda, Izumi Nagata
Polyarteritis nodosa (PAN) is a rare systemic necrotizing arteritis that involves small- and medium-sized arteries in various organs. Although aneurysm formation in visceral arteries is a typical finding in PAN, intracranial aneurysms are much less common, and only a few cases of aneurysm rupture associated with this disease have been documented. In this paper, the authors report on a ruptured PAN aneurysm of the anterior cerebral artery; the lesion was trapped and resected. On histological examination, extensive fibrinoid necrosis and an inflammatory infiltration of leukocytes were seen in the aneurysm wall...
January 2002: Journal of Neurosurgery
J P de Jager
BACKGROUND: Polymyalgia rheumatica (PMR) needs to be considered in the patient over 55 years of age who presents with stiffness and pain. It appears to exist in a continuum with giant cell arteritis (GCA), and the differential diagnosis is large. It may affect one in 200 patients in this age group. Corticosteroid toxicity is a major problem, either because of inappropriate dosage or prolonged disease. OBJECTIVE: To provide an up to date understanding of the concepts of this group of disorders in order to allow rapid recognition, better management, and to minimise toxicity of the necessary treatment...
July 2001: Australian Family Physician
S Matsubara, K Fushimi, K Ogawa, H Kikkawa, A Nakata, R Kameda, M Kikuchi, K Naito, K Ikezawa
BACKGROUND: The Lewis rat among highly inbred strains exhibits significant airway hyperresponsiveness (AHR) following intravenous administration of Sephadex G-200 (Sephadex). The aim of this study was to investigate the association of Sephadex-induced AHR with changes in airway inflammation in Lewis rats. METHODS: A suspension (0.5 mg/ml/rat) of Sephadex was intravenously administered to male Lewis rats on days 0, 2 and 5. Measurement of airway responsiveness to serotonin, bronchoalveolar lavage (BAL) and histological study were performed on day 2-11...
May 1998: International Archives of Allergy and Immunology
J G Pereira Arias, J A Gallego Sánchez, J Larrinaga Simón, N Prieto Ugidos, L Estallo Laliena, C Bernuy Malfaz
Inflammatory iliac aneurysms are uncommon and account for 1-2% of total abdominal aneurysms. These aneurysms are more susceptible to present urological symptoms and are difficult to diagnose because of their uncommon incidence and location in the deep pelvis which makes them little accessible to physical examination. This case report presents one patient with right obstructive uropathy secondary to extrinsic ureteral trapping due to inflammatory iliac aneurysm which evolved favourably after ureterolysis, endoaneurysmectomy and interposition of aortoiliac graft...
March 1997: Actas Urologicas Españolas
R Kleemann, U Deschl, G Dietmann, O H Wilhelms, R Juchem, W Rebel, F Hartig
24 hours after an i.v. injection of 2 mg Sephadex G 200 particles ovalbumin sensitized Sprague Dawley rats show an antigen specific bronchial hyperreactivity and an unspecific hyperreactivity against serotonin. The aim of this study was to investigate the effects of Sephadex on blood parameters and lung pathology to find the morphological substrate of bronchial hyperreactivity in this animal model. In the blood neutrophilia (p < 0.01) but no eosinophilia was present. We conclude that a blood eosinophilia needs not to be necessarily correlated with hyperreactivity of the airways like claimed by other investigators for this animal model...
June 1996: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
R Quintero, H Muñoz, J Hasbún, R Pommer, J Gutiérrez, J Sánchez, G Hidalgo, E Caerstens, L Muñoz, R Ramírez
We present the first report in our country of endoscopic fetal surgery in a patient with a twin pregnancy and twin reversal arteral perfusion (TRAP sequence). We performed fetoscopic ligation of the umbilical cord of an acardiac twin at 26 week's gestation.
1995: Revista Chilena de Obstetricia y Ginecología
Y Noishiki, Y Tomizawa, Y Yamane, T Okoshi, S Satoh, A Matsumoto
We have previously demonstrated rapid and complete endothelialization in synthetic fabric vascular prostheses that have been pretreated with autologous venous tissue fragments. However, significant thrombogenicity has been a major problem when this method has been applied to small-diameter grafts. By masking the positively charged collagen fibrils in the tissue fragments with negatively charged heparin, we were able to overcome this problem. A canine jugular vein was resected, minced into tissue fragments, and suspended...
May 1993: Journal of Thoracic and Cardiovascular Surgery
H Yamaguchi, M Morisada
Administration of high doses of Na2EDTA or feeding animals a low calcium diet leads to angiolytic changes of the mesenteric arteries as reported in previous papers. Slight inflammatory reactions in the arterial wall including leucocytic infiltration and exudation could be demonstrated. The reason is thought to be the lack of morphological changes of the endothelium. As far as the endothelium was concerned a lift up phenomenon of the endothelial cells and the formation of subendothelial vacuoles was observed, but no endothelial gap formation or desquamation...
1985: Experimental Pathology
S D Sorden, R F Lemanske, W L Castleman
Airway eosinophilia has been proposed as a major pathogenetic event in bronchial asthma and airway hyperresponsiveness. Intravenous injection of Sephadex G200 in rats induces pulmonary and blood eosinophilia and alters pulmonary responsiveness to 5-hydroxytryptamine. To characterize the early pulmonary inflammatory responses following Sephadex administration, and to determine the timing of the onset of pulmonary eosinophilia relative to blood eosinophilia, Sprague-Dawley rats were injected intravenously with Sephadex G200 beads...
July 1990: Veterinary Pathology
I Takahashi, H Takamura, S Gotoh, H Sasaki, K Makino, N Suzuki, I Nishihara, T Ishikawa, M Andoh
A case of a dissecting aneurysm of the left posterior inferior cerebellar artery caused by giant cell angiitis is presented. A 22-year-old woman was admitted on August 30, 1990, with sudden onset of severe occipital headache and vomiting. Neurological examination on admission only showed severe meningismus. CT scan demonstrated subarachnoid hemorrhage and a small hematoma in the 4th ventricle. A left vertebral angiogram demonstrated that the left posterior inferior cerebellar artery was occluded at the lateral medullary segment...
March 1992: No Shinkei Geka. Neurological Surgery
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