Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Velma K Lopez, Estee Y Cramer, Robert Pagano, John M Drake, Eamon B O'Dea, Madeline Adee, Turgay Ayer, Jagpreet Chhatwal, Ozden O Dalgic, Mary A Ladd, Benjamin P Linas, Peter P Mueller, Jade Xiao, Johannes Bracher, Alvaro J Castro Rivadeneira, Aaron Gerding, Tilmann Gneiting, Yuxin Huang, Dasuni Jayawardena, Abdul H Kanji, Khoa Le, Anja Mühlemann, Jarad Niemi, Evan L Ray, Ariane Stark, Yijin Wang, Nutcha Wattanachit, Martha W Zorn, Sen Pei, Jeffrey Shaman, Teresa K Yamana, Samuel R Tarasewicz, Daniel J Wilson, Sid Baccam, Heidi Gurung, Steve Stage, Brad Suchoski, Lei Gao, Zhiling Gu, Myungjin Kim, Xinyi Li, Guannan Wang, Lily Wang, Yueying Wang, Shan Yu, Lauren Gardner, Sonia Jindal, Maximilian Marshall, Kristen Nixon, Juan Dent, Alison L Hill, Joshua Kaminsky, Elizabeth C Lee, Joseph C Lemaitre, Justin Lessler, Claire P Smith, Shaun Truelove, Matt Kinsey, Luke C Mullany, Kaitlin Rainwater-Lovett, Lauren Shin, Katharine Tallaksen, Shelby Wilson, Dean Karlen, Lauren Castro, Geoffrey Fairchild, Isaac Michaud, Dave Osthus, Jiang Bian, Wei Cao, Zhifeng Gao, Juan Lavista Ferres, Chaozhuo Li, Tie-Yan Liu, Xing Xie, Shun Zhang, Shun Zheng, Matteo Chinazzi, Jessica T Davis, Kunpeng Mu, Ana Pastore Y Piontti, Alessandro Vespignani, Xinyue Xiong, Robert Walraven, Jinghui Chen, Quanquan Gu, Lingxiao Wang, Pan Xu, Weitong Zhang, Difan Zou, Graham Casey Gibson, Daniel Sheldon, Ajitesh Srivastava, Aniruddha Adiga, Benjamin Hurt, Gursharn Kaur, Bryan Lewis, Madhav Marathe, Akhil Sai Peddireddy, Przemyslaw Porebski, Srinivasan Venkatramanan, Lijing Wang, Pragati V Prasad, Jo W Walker, Alexander E Webber, Rachel B Slayton, Matthew Biggerstaff, Nicholas G Reich, Michael A Johansson
During the COVID-19 pandemic, forecasting COVID-19 trends to support planning and response was a priority for scientists and decision makers alike. In the United States, COVID-19 forecasting was coordinated by a large group of universities, companies, and government entities led by the Centers for Disease Control and Prevention and the US COVID-19 Forecast Hub (https://covid19forecasthub.org). We evaluated approximately 9.7 million forecasts of weekly state-level COVID-19 cases for predictions 1-4 weeks into the future submitted by 24 teams from August 2020 to December 2021...
May 6, 2024: PLoS Computational Biology
#2
JOURNAL ARTICLE
Shahrul Azhar Md Hanif, Mohd Rohaizat Hassan, Muhammad Ridzwan Rafi'i, Ahmad Farid Nazmi Abdul Halim, Mohd 'Ammar Ihsan Ahmad Zamzuri, Muhammad Ismail, Siti Salwa Ibrahim, Massitah Mihat, Lokman Rejali, Muhammad Habiruddin Zubir, Muhammad Salihin Mahadi, Shazwanis Ahmad Ismail, Veshny Ganesan, Muhammad Fahmi Mohd Fadzil
BACKGROUND: Melioidosis, a tropical infectious disease caused by Burkholderia pseudomallei, is epidemic in most region in Southeast Asia with high case fatality. However, there is scanty information regarding the disease's epidemiological pattern, demographics, and underlying risk factors. METHOD: This 5-year retrospective study of 185 confirmed cases which were taken from the Negeri Sembilan Melioidosis Registry between 2018 and 2022. We aim to describe the incidence, mortality rate, case fatality, relationship with meteorology, and factors that influence mortality in this central region of Peninsular Malaysia...
May 6, 2024: PLoS Neglected Tropical Diseases
#3
JOURNAL ARTICLE
Mpho Silima, Nicola Christofides, Hannabeth Franchino-Olsen, Nataly Woollett, Franziska Meinck
In South Africa, Mental Health (MH), HIV, and Intimate Partner Violence (IPV) form a syndemic, that disproportionately affects women. These challenges are often co-occurring and create complex adversities for women. Recognising these intersections and the broader socio-cultural dynamics at play is crucial to understanding the layered experiences of these women and developing effective interventions. This research explores the experiences of the women living with at least two of the epidemics (HIV, IPV and or MH) and how they cope...
2024: PLOS Glob Public Health
#4
JOURNAL ARTICLE
Sali Hafez, Sharif A Ismail, Zandile Zibwowa, Nadin Alhamshary, Reem Elsayed, Mandeep Dhaliwal, Fiona Samuels, Ade Fakoya
Community action is broadly recognised as central to comprehensive and effective system responses to pandemics. However, there is uncertainty about how and where communities can be best supported to bolster long-term resilience and preparedness. We applied a typology of community interventions (Community Informing, Consulting, Involving, Collaborating or Empowering-or CICICE) to cover the diverse range of interventions identified across the literature and used this to structure a scoping review addressing three linked topics: (i) how CICICE interventions have been understood and applied in the literature on epidemic and pandemic preparedness; (ii) the spectrum of interventions that have been implemented to strengthen CICICE and (iii) what evidence is available on their effectiveness in influencing preparedness for current and future emergencies...
2024: PLOS Glob Public Health
#5
REVIEW
Amin Ullah, Rajeev K Singla, Zahra Batool, Dan Cao, Bairong Shen
Childhood obesity is a chronic inflammatory epidemic that affects children worldwide. Obesity affects approximately 1 in 5 children worldwide. Obesity in children can worsen weight gain and raise the risk of obesity-related comorbidities like diabetes and non-alcoholic fatty liver disease (NAFLD). It can also negatively impact the quality of life for these children. Obesity disrupts immune system function, influencing cytokine (interleukins) balance and expression levels, adipokines, and innate and adaptive immune cells...
May 6, 2024: Reviews in Endocrine & Metabolic Disorders
#6
JOURNAL ARTICLE
Tianyu Cheng, Xingfu Zou
In this paper, we introduce the notion of practically susceptible population, which is a fraction of the biologically susceptible population. Assuming that the fraction depends on the severity of the epidemic and the public's level of precaution (as a response of the public to the epidemic), we propose a general framework model with the response level evolving with the epidemic. We firstly verify the well-posedness and confirm the disease's eventual vanishing for the framework model under the assumption that the basic reproduction number <mml:math xmlns:mml="https://www...
May 6, 2024: Journal of Mathematical Biology
#7
JOURNAL ARTICLE
Amy Adair, Li Lynn Tan, Jackson Feng, Jason Girkin, Nathan Bryant, Mingyang Wang, Francesca Mordant, Li-Jin Chan, Nathan W Bartlett, Kanta Subbarao, Phillip Pymm, Wai-Hong Tham
UNLABELLED: Human coronavirus (hCoV) OC43 is endemic to global populations and usually causes asymptomatic or mild upper respiratory tract illness. Here, we demonstrate the neutralization efficacy of isolated nanobodies from alpacas immunized with the S1B and S1C domain of the hCoV-OC43 spike glycoprotein. A total of 40 nanobodies bound to recombinant OC43 protein with affinities ranging from 1 to 149 nM. Two nanobodies WNb 293 and WNb 294 neutralized virus at 0.21 and 1.79 nM, respectively...
May 6, 2024: Journal of Virology
#8
JOURNAL ARTICLE
Ashlee Candelaria, Lauren Marek, Deborah Kanda, Jamie Griego, Teresa Rutledge
Background: The opioid epidemic is a public health crisis. However, opioid prescription recommendations have not been established in gynecological oncology, and guidelines that incorporate patient-reported pain are lacking. Objectives: The article aims to evaluate prescribing patterns, utilization, and patient-reported pain control in gynecological oncology patients at a large tertiary academic center. Methods: This was a two-phase, prospective cohort study. For Phase 1, patients undergoing hysterectomy through the gynecological oncology division at the University of New Mexico were enrolled...
May 6, 2024: Journal of Women's Health
#9
JOURNAL ARTICLE
Zulqurnain Sabir, Atef F Hashem, Zill E Shams, M A Abdelkawy
In this study, a stochastic computing structure is provided for the numerical solutions of the SIRC epidemic delay differential model, i.e. SIRC-EDDM using the dynamics of the COVID-19. The design of the scale conjugate gradient (CG) neural networks (SCGNNs) is presented for the numerical treatment of SIRC-EDDM. The mathematical model is divided into susceptible <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>S</mml:mi><mml:mo>(</mml:mo><mml:mi>ρ</mml:mi><mml:mo>)</mml:mo></mml:mrow><mml:mo>,</mml:mo></mml:math> recovered <mml:math xmlns:mml="https://www...
May 6, 2024: Computer Methods in Biomechanics and Biomedical Engineering
#10
REVIEW
Zamasomi P B Luvuno, Ebenezer Wiafe, NomaKhosi Mpofana, Makgobole M Urusla, Celenkosini T Nxumalo
BACKGROUND: Targeted interventions for key populations remain critical for realisation of epidemic control for human immunodeficiency virus (HIV) infection because of the causal relationship between HIV infection in the general population and among key population groups. AIM: To consolidate evidence on the fast-track interventions towards achieving HIV epidemic control among key populations. METHODS: A rapid scoping review was conducted using the methodological framework by Arksey and O' Malley...
April 8, 2024: African Journal of Primary Health Care & Family Medicine
#11
JOURNAL ARTICLE
Weiqi Chen, Linbin Wang
Under the new coronavirus epidemic, the implementation of public health measures has generated some resistance in countries around the world. The essence of examining the human rights claims of those who oppose the epidemic is that they have a too narrow understanding of individual human rights and ignore the obligation implications of human rights itself. From the historical point of view, health and epidemic prevention is the objective necessity of the survival and development of human society; From the ethical point of view, the joint fight against the epidemic is the moral obligation of the coordinated development of individuals and society...
May 15, 2024: Heliyon
#12
JOURNAL ARTICLE
Mitch Brinkkemper, Meliawati Poniman, Esther Siteur-van Rijnstra, Widad Ait Iddouch, Tom P L Bijl, Denise Guerra, Khadija Tejjani, Marloes Grobben, Farien Bhoelan, Denzel Bemelman, Ronald Kempers, Marit J van Gils, Kwinten Sliepen, Toon Stegmann, Yme U van der Velden, Rogier W Sanders
Zoonotic events by sarbecoviruses have sparked an epidemic (severe acute respiratory syndrome coronavirus [SARS-CoV]) and a pandemic (SARS-CoV-2) in the past two decades. The continued risk of spillovers from animals to humans is an ongoing threat to global health and a pan-sarbecovirus vaccine would be an important contribution to pandemic preparedness. Here, we describe multivalent virosome-based vaccines that present stabilized spike proteins from four sarbecovirus strains, one from each clade. A cocktail of four monovalent virosomes or a mosaic virosome preparation induced broad sarbecovirus binding and neutralizing antibody responses in mice...
May 17, 2024: IScience
#13
JOURNAL ARTICLE
Emily Kleinbart, Haley Tornberg, Christopher Rivera-Pintado, Krystal Hunter, Matthew T Kleiner, Lawrence S Miller, Mark Pollard, Catherine J Fedorka
BACKGROUND: Given the current opioid epidemic, it is crucial to highly regulate the prescription of narcotic medications for pain management. The use of electronic prescriptions (e-scripts) through the hospital's electronic medical record platform allows physicians to fill opioid prescriptions in smaller doses, potentially limiting the total quantity of analgesics patients have access to and decreasing the potential for substance misuse. The purpose of this study is to determine how the implementation of e-scripts changed the quantity of opioids prescribed following shoulder surgeries...
May 2024: JSES Rev Rep Tech
#14
JOURNAL ARTICLE
Cunling Yan, Xiaoyu Liu, Ning Zhang, Ying Liu, Bingjie Wang, Caihong Sun, Yunli Tang, Yue Qi, Bingyan Yu, Luhao Zhang, Ning Ning
BACKGROUND: Strengthening the construction of community resilience and reducing disaster impacts are on the agenda of the Chinese government. The COVID-19 pandemic could alter the existing community resilience. This study aims to explore the dynamic change trends of community resilience in China and analyze the primary influencing factors of community resilience in the context of COVID-19, as well as construct Community Resilience Governance System Framework in China. METHODS: A community advancing resilience toolkit (CART) was used to conduct surveys in Guangdong, Sichuan, and Heilongjiang provinces in China in 2015 and 2022, with community resilience data and information on disaster risk awareness and disaster risk reduction behaviors of residents collected...
2024: Frontiers in Public Health
#15
REVIEW
Joao P De Aquino, Matthew E Sloan, Julio C Nunes, Gabriel P A Costa, Jasmin L Katz, Debora de Oliveira, Jocelyn Ra, Victor M Tang, Ismene L Petrakis
Alcohol use disorder (AUD) and chronic pain disorders are pervasive, multifaceted medical conditions that often co-occur. However, their comorbidity is often overlooked, despite its prevalence and clinical relevance. Individuals with AUD are more likely to experience chronic pain than the general population. Conversely, individuals with chronic pain commonly alleviate their pain with alcohol, which may escalate into AUD. This narrative review discusses the intricate relationship between AUD and chronic pain...
May 1, 2024: American Journal of Psychiatry
#16
REVIEW
Thomas R Kosten
Substance use disorders (SUD) present a worldwide challenge with few effective therapies except for the relative efficacy of opioid pharmacotherapies, despite limited treatment access. However, the proliferation of illicit fentanyl use initiated a dramatic and cascading epidemic of lethal overdoses. This rise in fentanyl overdoses regenerated an interest in vaccine immunotherapy, which, despite an optimistic start in animal models over the past 50 years, yielded disappointing results in human clinical trials of vaccines against nicotine, stimulants (cocaine and methamphetamine), and opioids...
May 1, 2024: American Journal of Psychiatry
#17
JOURNAL ARTICLE
M H Liu, Y X Sun, Z L Li, L J Zhang, S H Wu, X G Ma, Y H Liu, L Li
Objective: To understand the status of tuberculosis diagnosis and treatment capacity and the development and changes of tuberculosis diagnosis and treatment in provincial and municipal designated medical institutions in China from 2017 to 2022, so as to provide a basis for the formulation of relevant policies for the improvement and development of designated medical institutions for tuberculosis and the tuberculosis prevention and treatment service system, and to provide reasonable support for further strengthening the capacity of designated medical institutions for tuberculosis...
May 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
#18
REVIEW
Mala Kamboj, R Keerthika, Anjali Narwal, Ambika Gupta, Anju Devi, Adarsh Kumar, Gitika Sharma
PURPOSE: Oral diseases act as a silent epidemic, and the pathogenetic role of interleukin-33/ suppression of tumorigenicity-2 axis (IL-33/ST2) remains unclear due to a lack of literature. This review has attempted to highlight the importance of this axis in oral diseases, which may be helpful in developing therapeutic modalities required to halt disease progression. MATERIALS AND METHODS: A thorough search was conducted using various databases. Original research articles that assessed both IL-33 and ST2 levels in oral diseases using different techniques were included in the review...
May 3, 2024: Advances in Medical Sciences
#19
JOURNAL ARTICLE
Oliver Nørholm Kempf, Thora Wesenberg Helt, Klaus Birkelund Johansen, Charlotte Rittig, Louise Lundby-Christensen, Marianne Sjølin Frederiksen, Pernille Mathiesen, Malene Boas, Preben Berg Nielsen, Annie Ellermann, Klaus Børch, Jens Jakob Petersen, Thomas Houmann Petersen, Cæcilie Trier Sønderskov, Jesper Andersen, Rasmus Gaardskær Nielsen, Eva Mosfeldt Jeppesen, Vibeke Brix Christensen
INTRODUCTION: To assess the effect of long-term isolation on the mental state of Danish youth. This study aimed to investigate trends in paracetamol overdoses among people under 18 years of age in Denmark during Covid-19 restrictions as an indicator of mental health. METHODS: All patients under the age of 18 years presenting with paracetamol overdose at one of the 18 paediatric departments in Denmark from 2016 to 2021 were included. They were identified in all Danish hospital databases using specific diagnostic codes...
April 16, 2024: Danish Medical Journal
#20
JOURNAL ARTICLE
Suneesh Kaimala, Shareena Saeed Lootah, Neha Mehra, Challagandla Anil Kumar, Saeeda Al Marzooqi, Prabha Sampath, Suraiya Anjum Ansari, Bright Starling Emerald
Obesity is a multifactorial disease that is part of today's epidemic and also increases the risk of other metabolic diseases. Long noncoding RNAs (lncRNAs) provide one tier of regulatory mechanisms to maintain metabolic homeostasis. Although lncRNAs are a significant constituent of the mammalian genome, studies aimed at their metabolic significance, including obesity, are only beginning to be addressed. Here, a developmentally regulated lncRNA, termed as obesity related (Obr), whose expression in metabolically relevant tissues such as skeletal muscle, liver, and pancreas is altered in diet-induced obesity, is identified...
May 5, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
