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Pain improvement for Lumbar disk degeneration

A Spallone, M Çelniku
A 49 years-old man came to our attention with severe flaccid paraparesis occurring 10 days before, almost immediately after he had immerged his legs in boiling water for treating his severe left lombo-crural pain. This was known to be due to a right L3-L4 herniated disk diagnosed by MRI. At the examination he showed severe motor paresis and absent reflexes of his lower limbs, whilst crural pain was very mild and sensation and urinary function were unaffected. The results of his neurological examination led us to suspect an acute motor axon degeneration related to the heating shock...
October 11, 2016: World Neurosurgery
David C Noriega, Francisco Ardura, Ruben Hernández-Ramajo, Miguel Angel Martín-Ferrero, Israel Sánchez-Lite, Borja Toribio, Mercedes Alberca, Veronica García, José Maria Moraleda, Ana Sánchez, Javier García-Sancho
BACKGROUND: Degenerative disc disease often causes severe low-back pain, a public health problem with huge economic and life quality impact. Chronic cases often require surgery, which may lead to biomechanical problems and accelerated degeneration of the adjacent segments. Autologous mesenchymal stromal cells (MSC) treatments have shown feasibility, safety and strong indications of clinical efficacy. We present here a randomized, controlled trial using allogeneic MSC, which are logistically more convenient than autologous cells...
September 21, 2016: Transplantation
Rebecca J Crawford, Thomas Volken, Stephanie Valentin, Markus Melloh, James M Elliott
BACKGROUND: The spinal column including its vertebrae and disks has been well examined and extensively reported in relation to age-aggregated degeneration. In contrast, paravertebral muscles are poorly represented in describing normative degeneration. Increasing evidence points to the importance of paravertebral muscle quality in low back health, and their potential as a modifiable factor in low back pain (LBP). Studies examining normative decline of paravertebral muscles are needed to advance the field's etiological understanding...
2016: Scoliosis and Spinal Disorders
Lei Dang, Zhongqiang Chen, Xiaoguang Liu, Zhaoqing Guo, Qiang Qi, Weishi Li, Yan Zeng, Liang Jiang, Feng Wei, Chuiguo Sun, Zhongjun Liu
BACKGROUND: Lumbar disk herniation in adults is thought to be caused by repetitive overloading and age-rated degenerative changes. However, these causes are absent in children and adolescent patients. We assume that structural malformations in the lumbar spine could predispose intervertebral disks to early degeneration and hence need to be surgically fused. This issue has never been raised before. OBJECTIVE: To investigate the assumption that structural malformations in the lumbar spine could predispose intervertebral disks to early degeneration and hence need to be surgically fused...
December 2015: Neurosurgery
Salih Müjde, Nuri Erel, Fırat Ozan
OBJECTIVE: The aim of this study was to assess the outcomes of fusion technique via posterior instrumentation in combination with transverse decompression in the surgical treatment of degenerative lumbar canal stenosis. METHODS: Forty-five patients-39 women (86.7%) and 6 men (13.3%)-were included. Mean age was 58.68±8.63 years with mean follow-up of 51.71±20.96 months. Preoperative and postoperative clinical evaluation was performed using the Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) for overall pain...
2015: Acta Orthopaedica et Traumatologica Turcica
Jun Sato, Seiji Ohtori, Sumihisa Orita, Kazuyo Yamauchi, Yawara Eguchi, Nobuyasu Ochiai, Kazuki Kuniyoshi, Yasuchika Aoki, Junichi Nakamura, Masayuki Miyagi, Miyako Suzuki, Gou Kubota, Kazuhide Inage, Takeshi Sainoh, Kazuki Fujimoto, Yasuhiro Shiga, Koki Abe, Hiroto Kanamoto, Gen Inoue, Kazuhisa Takahashi
PURPOSE: Extreme lateral interbody fusion provides minimally invasive treatment of spinal deformity, but complications including nerve and psoas muscle injury have been noted. To avoid nerve injury, mini-open anterior retroperitoneal lumbar interbody fusion methods using an approach between the aorta and psoas, such as oblique lumbar interbody fusion (OLIF) have been applied. OLIF with percutaneous pedicle screws without posterior decompression can indirectly decompress the spinal canal in lumbar degenerated spondylolisthesis...
August 6, 2015: European Spine Journal
Yi Yang, Ying Hong, Hao Liu, Yueming Song, Tao Li, Limin Liu, Quan Gong
PURPOSE: A retrospective study was conducted to compare clinical outcome with radiographic data and clinical complications between isobar posterior dynamic stabilization (IPDS, Scient'x, France) and posterior lumbar inter-body fusion (PLIF) for lumbar degenerative disease. METHODS: 113 consecutive patients (IPDS group, N=62; PLIF group, N=51) with lumbar degenerative disease were operated on between March 2009 and November 2011. Patient charts, radiographic films and medical records were reviewed...
September 2015: Clinical Neurology and Neurosurgery
Takahito Fujimori, Hai Le, William W Schairer, Sigurd H Berven, Erion Qamirani, Serena S Hu
Study Design Retrospective cohort study. Objective To compare the clinical and radiographic outcomes of transforaminal lumbar interbody fusion (TLIF) and posterolateral lumbar fusion (PLF) in the treatment of degenerative spondylolisthesis. Methods This study compared 24 patients undergoing TLIF and 32 patients undergoing PLF with instrumentation. The clinical outcomes were assessed by visual analog scale (VAS) for low back pain and leg pain, physical component summary (PCS) of the 12-item Short-Form Health Survey, and the Oswestry Disability Index (ODI)...
April 2015: Global Spine Journal
Mingyuan Yang, Chao Li, Ziqiang Chen, Yushu Bai, Ming Li
BACKGROUND: Decompression and fusion is considered as the 'gold standard' for the treatment of degenerative lumbar diseases, however, many disadvantages have been reported in several studies, recently like donor site pain, pseudoarthrosis, nonunion, screw loosening, instrumentation failure, infection, adjacent segment disease (ASDis) and degeneration. Dynamic neutralization system (Dynesys) avoids many of these disadvantages. This system is made up of pedicle screws, polyethylene terephthalate cords, and polycarbonate urethane spacers to stabilize the functional spinal unit and preserve the adjacent motion after surgeries...
November 2014: Indian Journal of Orthopaedics
Prashanth J Rao, Ajanthan Loganathan, Vivian Yeung, Ralph J Mobbs
BACKGROUND: There is limited information on clinical outcomes after anterior lumbar interbody fusion (ALIF) based on the indications for surgery. OBJECTIVE: To compare the clinical and radiological outcomes of ALIF for each surgical indication. METHODS: This prospective clinical study included 125 patients who underwent ALIF over a 2-year period. The patients were evaluated preoperatively and postoperatively. Outcome measures included the Short Form-12, Oswestry Disability Index, Visual Analog Scale, and Patient Satisfaction Index...
January 2015: Neurosurgery
Felipe Vieira-Pellenz, Angel Oliva-Pascual-Vaca, Cleofás Rodriguez-Blanco, Alberto Marcos Heredia-Rizo, François Ricard, Ginés Almazán-Campos
OBJECTIVE: To evaluate the short-term effect on spinal mobility, pain perception, neural mechanosensitivity, and full height recovery after high-velocity, low-amplitude (HVLA) spinal manipulation (SM) in the lumbosacral joint (L5-S1). DESIGN: Randomized, double-blind, controlled clinical trial with evaluations at baseline and after intervention. SETTING: University-based physical therapy research clinic. PARTICIPANTS: Men (N=40; mean age ± SD, 38 ± 9...
September 2014: Archives of Physical Medicine and Rehabilitation
Michael Luchtmann, Yvonne Steinecke, Sebastian Baecke, Ralf Lützkendorf, Johannes Bernarding, Jana Kohl, Boris Jöllenbeck, Claus Tempelmann, Patrick Ragert, Raimund Firsching
Chronic pain is one of the most common health complaints in industrial nations. For example, chronic low back pain (cLBP) disables millions of people across the world and generates a tremendous economic burden. While previous studies provided evidence of widespread functional as well as structural brain alterations in chronic pain, little is known about cortical changes in patients suffering from lumbar disc herniation. We investigated morphometric alterations of the gray and white matter of the brain in patients suffering from LDH...
2014: PloS One
Michael Athanasakopoulos, Andreas F Mavrogenis, George Triantafyllopoulos, Spiros Koufos, Spiros G Pneumaticos
Few clinical studies have reported polyetheretherketone (PEEK) rod pedicle screw spinal instrumentation systems (CD-Horizon Legacy PEEK rods; Medtronic, Minneapolis, Minnesota). This article describes a clinical series of 52 patients who underwent posterior spinal fusion using the PEEK Rod System between 2007 and 2010. Of the 52 patients, 25 had degenerative disk disease, 10 had lateral recess stenosis, 6 had degenerative spondylolisthesis, 6 had lumbar spine vertebral fracture, 4 had combined lateral recess stenosis and degenerative spondylolisthesis, and 1 had an L5 giant cell tumor...
July 2013: Orthopedics
Dae-Woong Kwon, Kyung-Hyun Kim, Jeong-Yoon Park, Dong-Kyu Chin, Keun-Su Kim, Young-Eun Cho, Sung-Uk Kuh
PURPOSE: The posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) techniques are commonly used surgical methods for wide indications such as degeneration or trauma. Although they are rarely required for lumbar disk disease in younger patients, there are a few children and adolescents who are indicated for PLIF or TLIF for other reasons, such as congenital severe stenosis with or without lumbar instability that requires wide decompression or severe bony spur that need to be removed...
August 2013: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Hye-Young Kim, Byung-Wan Choi
OBJECT: This study was intended to objectively demonstrate the effect of interspinous implantation through preoperative and postoperative radiological analyses in degenerative lumbar spinal stenosis. METHODS: This study included 20 segments of 14 cases that had been diagnosed as spinal stenosis through physical and radiological findings and had interspinous implantation (X-stop(®)). On simple radiography, height and width of the intervertebral foramen, height of the anterior and posterior intervertebral disks, and interbody angle were measured...
April 2013: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
Choon Sung Lee, Dong-Ho Lee, Chang Ju Hwang, Hyoungmin Kim, Hyounmin Noh
STUDY DESIGN: Retrospective clinical and radiographic assessment of 21 levels of 18 consecutive patients treated using total lumbar disk replacement (TDR) for degenerative disk disease. OBJECTIVES: To report clinical and radiographic outcomes after TDR using the Mobidisc prosthesis. In addition, to determine whether there is a correlation between clinical and radiologic outcomes and prosthesis positioning. SUMMARY OF BACKGROUND DATA: TDR for lumbar degenerative disk disease is reported to provide good clinical and radiographic outcomes...
May 2014: Journal of Spinal Disorders & Techniques
S Ferrari, F Costa, M Fornari
Spondylolisthesis is a pathological condition caused by the slipping of a vertebral body, compared to the underlying structure, following structural and/or degenerative changes to the spine. Studies have attempted evidence to the connection between the natural history of spondylolisthesis, the degree and progression of the slip factor, as well as the pain and disability. Studies have reported a high level of heterogeneity of these factors in different patients as well as difficulty in predicting behaviour. It has been suggested that vertebral instability, independent of the slip factor, could be considered the most important factor to be treated conservatively or surgically...
June 2012: European Journal of Physical and Rehabilitation Medicine
Jae-Sung Kim, Jeffrey S Kroin, Xin Li, Howard S An, Asokumar Buvanendran, Dongyao Yan, Kenneth J Tuman, Andre J van Wijnen, Di Chen, Hee-Jeong Im
INTRODUCTION: Degeneration of the interverterbral disk is as a cause of low-back pain is increasing. To gain insight into relationships between biological processes, structural alterations and behavioral pain, we created an animal model in rats. METHODS: Disk degeneration was induced by removal of the nucleus pulposus (NP) from the lumbar disks (L4/L5 and L5/L6) of Sprague Dawley rats using a 0.5-mm-diameter microsurgical drill. The degree of primary hyperalgesia was assessed by using an algometer to measure pain upon external pressure on injured lumbar disks...
2011: Arthritis Research & Therapy
Haktan Karaman, Adnan Tüfek, Gönül Ölmez Kavak, Sedat Kaya, Zeynep Baysal Yildirim, Ersin Uysal, Feyzi Celik
STUDY DESIGN: Prospective observational study. OBJECTIVE: Our aim is to investigate the efficacy and safety of TransDiscal Biacuplasty. SUMMARY OF BACKGROUND DATA: Chronic discogenic pain is one of the leading causes of low back pain; however, the condition is not helped by most non-invasive methods. The results of major surgical operations for these patients are unsatisfactory. Recently, attention has shifted to disk heating methods for treatment...
2010: International Journal of Medical Sciences
Michael Ogon, Alexander Tuschel
OBJECTIVE: Improvement of chronic low back pain caused by degenerative disc disease. Maintenance of motion in the treated segment. Reduction of possible adjacent-segment degeneration. INDICATIONS: Chronic low back pain, resistant to conservative therapy due to painful degeneration of the intervertebral disks ("degenerative disk disease"). CONTRAINDICATIONS: Spondylolisthesis, scoliosis, osteoporosis, infection, spinal stenosis, degeneration of the vertebral articulations, (pathologic) fractures...
November 2010: Operative Orthopädie und Traumatologie
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