Chenfei Wang, Wei He, Feifei Wang, Haiyang Yong, Tao Bo, Dingjin Yao, Yitong Zhao, Chaolan Pan, Qiaoyu Cao, Si Zhang, Ming Li
Currently, many types of non-linear topological structure polymers, such as brush-shaped, star, branched and dendritic structures, have captured much attention in the field of gene delivery and nanomedicine. Compared with linear polymers, non-linear topological structural polymers offer many advantages, including multiple terminal groups, broad and complicated spatial architecture and multi-functionality sites to enhance gene delivery efficiency and targeting capabilities. Nevertheless, the complexity of their synthesis process severely hampers the development and applications of nonlinear topological polymers...
January 27, 2024: Journal of Nanobiotechnology