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https://www.readbyqxmd.com/read/29222719/longevity-of-visual-improvements-following-transcorneal-electrical-stimulation-and-efficacy-of-retreatment-in-three-individuals-with-retinitis-pigmentosa
#1
Ava K Bittner, Kenneth Seger
PURPOSE: A small-scale randomized controlled trial conducted by our group found that four of seven retinitis pigmentosa (RP) subjects who received six weekly Transcorneal Electrical Stimulation (TES) sessions developed significant improvements in visual acuity (VA), quick contrast sensitivity function (qCSF), and/or Goldmann visual fields (GVF). We longitudinally monitored three of these participants for declining visual function due to natural RP progression to determine the duration of their responses and administered retreatments...
December 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29220705/therapeutic-landscapes-and-longevity-wellness-tourism-in-bama
#2
Liyuan Huang, Honggang Xu
Due to the rising demand for healthcare products and concern over environmental pollution, wellness tourism has been booming in China in recent years. The therapeutic landscape theory provides a multi-scale interpretation of wellness tourism to explore how wellness tourists achieve health in healing places. By presenting the results of 83 interviews conducted in Bama, China, this study reveals that the "longevity village" Bama, endorsed by centenarians, provides a retreat that combines natural beauty and a harmonious neighbourhood for wellness tourists...
November 28, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29220418/plant-mediated-female-transcriptomic-changes-post-mating-in-a-tephritid-fruit-fly-bactrocera-tryoni
#3
Kumaran Nagalingam, Chloé A van der Burg, Yujia Qin, Stephen L Cameron, Anthony R Clarke, Peter J Prentis
Female post-mating behaviours are regulated by complex factors involving males, females and the environment. In insects, plant secondary compounds that males actively forage for, may indirectly modify female behaviours by altering male behaviour and physiology. In the tephritid fruit fly, Bactrocera tryoni, females mated with males previously fed on plant-derived phenylpropanoids (= 'lures' based on usage in tephritid literature), have longer mating refractoriness, greater fecundity and reduced longevity than females mated with non-lure fed males...
December 6, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29219151/familial-hypercholesterolaemia
#4
REVIEW
Joep C Defesche, Samuel S Gidding, Mariko Harada-Shiba, Robert A Hegele, Raul D Santos, Anthony S Wierzbicki
Familial hypercholesterolaemia is a common inherited disorder characterized by abnormally elevated serum levels of low-density lipoprotein (LDL) cholesterol from birth, which in time can lead to cardiovascular disease (CVD). Most cases are caused by autosomal dominant mutations in LDLR, which encodes the LDL receptor, although mutations in other genes coding for proteins involved in cholesterol metabolism or LDLR function and processing, such as APOB and PCSK9, can also be causative, although less frequently...
December 7, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29218330/interactive-effects-of-parental-age-on-offspring-fitness-and-age-assortative-mating-in-a-wild-bird
#5
E Keith Bowers, Scott K Sakaluk, Charles F Thompson
Variation in parental age can have important consequences for offspring fitness and the structure of populations and disease transmission. However, our understanding of the effects of parental age on offspring in natural populations is limited. Here, we investigate consequences of parental age for offspring fitness and test for age-assortative mating in a short-lived bird, the house wren (Troglodytes aedon). Offspring immunoresponsiveness increased with maternal age and decreased with paternal age, but the strength of these effects varied with the age of one's mate...
June 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29217082/-prosthetic-genioplasty-versus-osseous-genioplasty-in-aesthetic-chin-augmentation-literature-review-and-knowledge-update
#6
A Baus, K Rem, M Revol, S Cristofari
Chin augmentation is commonly practiced, whether in microgenia treatment, in cases of orthognathic or cosmetic surgery. Located at the crossroads of many specialties, the technique choice still differs according to the surgeon specialiy. A large number of publications on the subject are available. A comparaison between different surgical methods is therefore possible concerning their indications and their complication. The purpose of this study was to carry out a literature review, with updating knowledge, as well as a synthesis indication regarding aesthetic osseous and alloplastic genioplasty...
December 4, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29214546/biology-of-a-neotropical-harlequin-stink-bug-runibia-perspicua-f
#7
A L Marsaro, A R Panizzi, T Lucini
Laboratory and field studies were conducted with nymphs and adults of the Neotropical stink bug Runibia perspicua (F.) to evaluate their biology on plants. Total nymph mortality was ca. 13% on immature fruits of Brunfelsia australis Benth. (IFBA) and 90% on raw shelled peanuts, Arachis hypogaea L. (RSP); no nymphs survived on immature pods of green bean, Phaseolus vulgaris L., or on immature fruits of privet, Ligustrum lucidum Ait. Nymph developmental time was ca. 36 on IFBA and 55 days on RSP. Body weight was significantly greater when nymphs were raised isolated compared to those raised in groups...
December 7, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/29211978/revamping-mitochondrial-shape-to-live-longer
#8
Lena Pernas, Luca Scorrano
Whether and how mitochondria connect reduced energy intake to healthy aging are unclear. In this issue of Cell Metabolism, Weir et al. (2017) find that constitutive AMPK activation and dietary restriction promote longevity in C. elegans via remodeling of the mitochondrial network and fatty acid oxidation in peripheral tissues.
December 5, 2017: Cell Metabolism
https://www.readbyqxmd.com/read/29211691/long-term-monitoring-of-water-treatment-technology-designed-for-radium-removal-removal-efficiencies-and-norm-formation
#9
Liie Hill, Siiri Suursoo, Madis Kiisk, Alar Jantsikene, Nele Nilb, Rein Munter, Enn Realo, Rein Koch, Kaisa Putk, Maria Leier, Taavi Vaasma, Kadri Isakar
A drinking water treatment plant in Viimsi, Estonia, was monitored over three years for iron, manganese, radium-226, radium-228, as well as their daughter nuclides, in order to determine the efficiency of the treatment process, gain an insight into the removal mechanisms and interactions between radium, iron, and manganese, and assess the overall longevity and performance of the technology along with the possible build-up of NORM in the treatment process. During the study, samples were collected from raw water, first and second stage filtrate, consumer water, backwash water and filter materials...
December 6, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29210129/effect-of-resveratrol-and-pterostilbene-on-aging-and-longevity
#10
REVIEW
Yi-Rong Li, Shiming Li, Chi-Chien Lin
Over the past years, several studies have found that foods rich in polyphenols protect against age-related disease, such as atherosclerosis, cardiovascular disease, cancer, arthritis, cataracts, osteoporosis, type 2 diabetes (T2D), hypertension and Alzheimer's disease. Resveratrol and pterostilbene, the polyphenol found in grape and blueberries, have beneficial effects as anti-aging compounds through modulating the hallmarks of aging, including oxidative damage, inflammation, telomere attrition and cell senescence...
December 6, 2017: BioFactors
https://www.readbyqxmd.com/read/29210015/internet-use-social-networks-loneliness-and-quality-of-life-among-adults-aged-50-and-older-mediating-and-moderating-effects
#11
Rabia Khalaila, Adi Vitman-Schorr
BACKGROUND: The increase in longevity of people on one hand, and on the other hand the fact that the social networks in later life become increasingly narrower, highlights the importance of Internet use to enhance quality of life (QoL). However, whether Internet use increases or decreases social networks, loneliness, and quality of life is not clear-cut. PURPOSES: To explore the direct and/or indirect effects of Internet use on QoL, and to examine whether ethnicity and time the elderly spent with family moderate the mediation effect of Internet use on quality of life throughout loneliness...
December 5, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29209823/autologous-arteriovenous-fistulas-for-hemodialysis-using-microsurgery-techniques-in-children-weighing-less-than-20%C3%A2-kg
#12
Vasiliki Karava, Pascal Jehanno, Theresa Kwon, Georges Deschênes, Marie-Alice Macher, Pierre Bourquelot
BACKGROUND: This study aimed to describe the efficiency and longevity of arteriovenous fistula (AVF) for hemodialysis (HD) in children weighing ≤20 kg. METHODS: We collected data of all AVFs created using microsurgery techniques between 1988 and 2015. Success was considered as the ability to use the AVF for HD. Primary and secondary patency rates were measured. RESULTS: Forty-eight AVFs (35 forearm, 13 upper arm) were created in 41 children with a median weight of 13...
December 5, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29209583/what-makes-the-optimal-wound-healing-material-a-review-of-current-science-and-introduction-of-a-synthetic-nanofabricated-wound-care-scaffold
#13
REVIEW
Matthew R MacEwan, Sarah MacEwan, Tamas R Kovacs, Joel Batts
Wound matrix materials are used to improve the regeneration of dermal and epidermal layers in both acute and chronic wounds. Contemporary wound matrices are primarily composed of biologic materials such as processed xenogeneic and allogeneic tissues. Unfortunately, existing biologic wound matrices possess multiple limitations including poor longevity, durability, strength, and enzymatic resistance required for persistent support for new tissue formation. A fully-synthetic, resorbable electrospun material (Restrata Wound Matrix, Acera, St...
October 2, 2017: Curēus
https://www.readbyqxmd.com/read/29209506/border-terriers-under-primary-veterinary-care-in-england-demography-and-disorders
#14
Dan G O'Neill, Elisabeth C Darwent, David B Church, Dave C Brodbelt
Background: The Border Terrier is a working terrier type that is generally considered to be a relatively healthy and hardy breed. This study aimed to characterise the demography and common disorders of Border Terriers receiving veterinary care in England using de-identified electronic patient record data within the VetCompass™ Programme. Results: Annual birth proportion for Border Terriers showed a decreasing trend from 1.46% in 2005 to 0.78% in 2014. The median adult bodyweight for males (10...
2017: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/29209423/the-physiological-effects-of-slow-breathing-in-the-healthy-human
#15
Marc A Russo, Danielle M Santarelli, Dean O'Rourke
Slow breathing practices have been adopted in the modern world across the globe due to their claimed health benefits. This has piqued the interest of researchers and clinicians who have initiated investigations into the physiological (and psychological) effects of slow breathing techniques and attempted to uncover the underlying mechanisms. The aim of this article is to provide a comprehensive overview of normal respiratory physiology and the documented physiological effects of slow breathing techniques according to research in healthy humans...
December 2017: Breathe
https://www.readbyqxmd.com/read/29209360/assortative-mating-by-ethnicity-in-longevous-families
#16
Paola Sebastiani, Anastasia Gurinovich, Harold Bae, Stacy L Andersen, Thomas T Perls
Recent work shows strong evidence of ancestry-based assortative mating in spouse pairs of the older generation of the Framingham Heart Study. Here, we extend this analysis to two studies of human longevity: the Long Life Family Study (LLFS), and the New England Centenarian Study (NECS). In the LLFS, we identified 890 spouse pairs spanning two generations, while in the NECS we used data from 102 spouse pairs including offspring of centenarians. We used principal components of genome-wide genotype data to demonstrate strong evidence of ancestry-based assortative mating in spouse pairs of the older generation and also confirm the decreasing trend of endogamy in more recent generations...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/29209284/the-sit-and-wait-hypothesis-in-bacterial-pathogens-a-theoretical-study-of-durability-and-virulence
#17
Liang Wang, Zhanzhong Liu, Shiyun Dai, Jiawei Yan, Michael J Wise
The intriguing sit-and-wait hypothesis predicts that bacterial durability in the external environment is positively correlated with their virulence. Since its first proposal in 1987, the hypothesis has been spurring debates in terms of its validity in the field of bacterial virulence. As a special case of the vector-borne transmission versus virulence tradeoff, where vector is now replaced by environmental longevity, there are only sporadic studies over the last three decades showing that environmental durability is possibly linked with virulence...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29209084/sublethal-effects-of-buprofezin-on-development-and-reproduction-in-the-white-backed-planthopper-sogatella-furcifera-hemiptera-delphacidae
#18
Ehsan Ali, Xun Liao, Peng Yang, Kaikai Mao, Xiaolei Zhang, Muhammad Shakeel, Abdalla M A Salim, Hu Wan, Jianhong Li
In the present study, the effects of sublethal concentrations of buprofezin on life-table traits of S. furcifera were evaluated for two consecutive generations (F0 and F1). Our results exhibited that the fecundity, life span (longevity) and hatchability of the F0 and F1 generations were significantly decreased at LC30 compared to the control. However, copulation was not significantly affected for the F0 or F1 generations at sublethal concentrations. The female life span was affected negatively at both treatments in F0 and at LC30 in F1, compared to the control...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29208615/association-between-exercise-and-the-risk-of-dementia-results-from-a-nationwide-longitudinal-study-in-china
#19
Zi Zhou, Jian Fu, Y Alicia Hong, Ping Wang, Ya Fang
OBJECTIVE: This study was conducted to examine the causal association between exercise and the risk of dementia among older Chinese adults. DESIGN: Longitudinal population-based study with a follow-up duration of 9 years. SETTING: Data for the Chinese Longitudinal Healthy Longevity Survey waves occurring from 2002 to 2011-2012 were extracted from the survey database. PARTICIPANTS: In total, 7501 dementia-free subjects who were older than 65 years were included at baseline...
December 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/29208024/selection-of-a-suitable-reference-gene-for-quantitative-gene-expression-in-mouse-lymph-nodes-after-vaccination
#20
Yung-Yi C Mosley, Harm HogenEsch
BACKGROUND: The quantification of gene expression is an important tool in the evaluation of the immune response to vaccines. Reliable reference genes for gene expression studies in mouse draining lymph nodes after vaccination have not been reported. RESULTS: The utility of seven potential reference genes was investigated using commercially available Taq-man primer/probe mixes. Results were evaluated with RefFinder, a web-based program including multiple algorithm methods such as geNorm, NormFinder, BestKeeper and the comparative delta-Ct...
December 6, 2017: BMC Research Notes
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