Jan Lubinski, Joanne Kotsopoulos, Pal Moller, Tuya Pal, Andrea Eisen, Larissa Peck, Beth Y Karlan, Amber Aeilts, Charis Eng, Louise Bordeleau, William D Foulkes, Nadine Tung, Fergus J Couch, Robert Fruscio, Teresa Ramon Y Cajal, Christian F Singer, Susan L Neuhausen, Dana Zakalik, Cezary Cybulski, Jacek Gronwald, Tomasz Huzarski, Klaudia Stempa, Jeffrey Dungan, Carey Cullinane, Olufunmilayo I Olopade, Kelly Metcalfe, Ping Sun, Steven A Narod
IMPORTANCE: Magnetic resonance imaging (MRI) surveillance is offered to women with a pathogenic variant in the BRCA1 or BRCA2 gene who face a high lifetime risk of breast cancer. Surveillance with MRI is effective in downstaging breast cancers, but the association of MRI surveillance with mortality risk has not been well defined. OBJECTIVE: To compare breast cancer mortality rates in women with a BRCA1 or BRCA2 sequence variation who entered an MRI surveillance program with those who did not...
February 29, 2024: JAMA Oncology