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Prostate cancer and ultrasound

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https://www.readbyqxmd.com/read/29771696/the-future-of-anesthesia-for-interventional-radiology
#1
Annie Amin, Jason Scott Lane
PURPOSE OF REVIEW: To review novel procedures in interventional radiology and describe anesthetic implications. RECENT FINDINGS: Noninvasive treatment options for patients who are nonsurgical candidates are on the rise. The complication rate for patients receiving anesthesia in the interventional radiology suite is higher than other nonoperating room anesthetizing locations. The investigative use of catheter-directed thrombolysis for acute submassive pulmonary embolism will likely lead to an increased demand for anesthesia assistance...
May 15, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29770311/-super-active-surveillance-mri-ultrasound-fusion-biopsy-and-ablation-for-less-invasive-management-of-prostate-cancer
#2
REVIEW
Jonathan B Bloom, Samuel A Gold, Graham R Hale, Kareem N Rayn, Vikram K Sabarwal, Ivane Bakhutashvili, Vladimir Valera, Baris Turkbey, Peter A Pinto, Bradford J Wood
Multiparametric magnetic resonance imaging (mpMRI) of the prostate has allowed clinicians to better visualize and target suspicious lesions during biopsy. Targeted prostate biopsies give a more accurate representation of the true cancer volume and stage so that appropriate treatment or active surveillance can be selected. Advances in technology have led to the development of MRI and ultrasound fusion platforms used for targeted biopsies, monitoring cancer progression, and more recently for the application of focal therapy...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29764692/combined-high-dose-rate-brachytherapy-and-external-beam-radiotherapy-for-clinically-localised-prostate-cancer
#3
Iosif Strouthos, Georgios Chatzikonstantinou, Nikolaos Zamboglou, Natasa Milickovic, Sokratis Papaioannou, Dimitra Bon, Constantinos Zamboglou, Claus Rödel, Dimos Baltas, Nikolaos Tselis
PURPOSE: To report the clinical outcomes and treatment-related toxicities after combined high-dose-rate (HDR) brachytherapy (BRT) with external beam radiotherapy (EBRT) for patients with clinically localised high-risk prostate cancer. MATERIAL AND METHODS: Between 2008 and 2012, three hundred and three consecutive patients with organ-confined high-risk prostate cancer were treated with definitive radiotherapy consisting of HDR-BRT followed by supplemental EBRT. The transrectal 3D-ultrasound-based HDR-BRT boost consisted of two single-fraction implants of 10...
May 12, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29758220/evaluation-of-an-aggressive-prostate-biopsy-strategy-in-men-younger-than-50-years-of-age
#4
Hanan Goldberg, Zachary Klaassen, Thenappan Chandrasekar, Christopher J D Wallis, Ants Toi, Rashid Sayyid, Bimal Bhindi, Michael Nesbitt, Andrew Evans, Theo van der Kwast, Joan Sweet, Nathan Perlis, Robert J Hamilton, Girish S Kulkarni, Antonio Finelli, Alexandre Zlotta, Neil Fleshner
INTRODUCTION: Longitudinal cohort studies and guidelines demonstrate that PSA ≥1 ng/mL in younger patients confer an increased risk of delayed prostate cancer (PC) death. In our institution we have used an aggressive biopsy strategy among younger patients with PSA of>1 ng/ml. Our objective was to determine the proportion of detected cancer and specifically, clinical significant cancer, with this strategy. METHODS: The prostate biopsy (PB) database at Princess Margaret Cancer Centre was queried for patients younger than 50 who underwent a first PB between 2000 and 2016...
May 11, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29757474/automated-patient-specific-transperineal-ultrasound-probe-setups-for-prostate-cancer-patients-undergoing-radiotherapy
#5
Saskia Maria Camps, Frank Verhaegen, Ben G L Vanneste, Peter H N de With, Davide Fontanarosa
PURPOSE: The use of ultrasound imaging is not widespread in prostate cancer radiotherapy workflows, despite several advantages (e.g. allowing real-time volumetric organ tracking). This can be partially attributed to the need for a trained operator during acquisition and interpretation of the images. We introduce and evaluate an algorithm that can propose a patient-specific transperineal ultrasound probe setup, based on a CT scan and anatomical structure delineations. The use of this setup during the simulation and treatment stage could improve usability of ultrasound imaging for relatively untrained operators (radiotherapists with less than one year experience with ultrasound)...
May 14, 2018: Medical Physics
https://www.readbyqxmd.com/read/29756298/primary-whole-gland-ablation-for-localized-prostate-cancer-with-high-intensity-focused-ultrasound-the-important-predictors-of-biochemical-recurrence
#6
Po Yen Chen, Po Hui Chiang, Yi Yang Liu, Yao Chi Chuang, Yuan Tso Cheng
OBJECTIVES: To identify predictive factors of biochemical recurrence for patients undergoing high-intensity focused ultrasound treatment for localized prostate cancer. METHODS: We retrospectively identified patients receiving whole-gland prostate ablation with high-intensity focused ultrasound for localized prostate cancer from 2009 to 2015. All the patients received pre-high-intensity focused ultrasound radical transurethral resection of the prostate. We included perioperative parameters as follows: age, preoperative prostate volume, stage of operation, initial prostate-specific antigen, T stage, postoperative prostate-specific antigen nadir, Gleason score, time to prostate-specific antigen nadir and the presence of prostate-specific antigen biochemical recurrence...
May 13, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29743538/which-technology-to-select-for-primary-focal-treatment-of-prostate-cancer-european-section-of-urotechnology-esut-position-statement
#7
REVIEW
Roman Ganzer, Vinodh Kumar Adithyaa Arthanareeswaran, Hashim U Ahmed, Andrea Cestari, Pascal Rischmann, Georg Salomon, Dogu Teber, Evangelos Liatsikos, Jens-Uwe Stolzenburg, Eric Barret
BACKGROUND: With growing interest in focal therapy (FT) of prostate cancer (PCa) there is an increasing armamentarium of treatment modalities including high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation (FLA), irreversible electroporation (IRE), vascular targeted photodynamic therapy (VTP), focal brachytherapy (FBT) and stereotactic ablative radiotherapy (SABR). Currently there are no clear recommendations as to which of these technologies are appropriate for individual patient characteristics...
May 9, 2018: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/29740844/association-between-male-accesory-gland-infections-and-prostate-cancer-in-turkish-men-a-case-control-study
#8
S Aykan, M Z Temiz, M Yilmaz, I Ulus, E Yuruk, A Y Muslumanoglu
It is well known that chronic inflammation contributes to several forms of human cancer. Although several studies have investigated the association between prostatitis and prostate cancer, there is a lack of specifically designed study about male accessory gland infections (MAGI) and prostate cancer co-occurrence. We aimed to investigate this association with a case-control study in Turkish men. A total of 155 patients were enrolled to the study. After the pathological examination of the transrectal ultrasound-guided prostate biopsy specimens, patients were divided the two groups as control and prostate cancer and the presence of MAGI was determined...
May 8, 2018: Andrologia
https://www.readbyqxmd.com/read/29733838/validation-of-pi-rads-version-2-for-the-detection-of-prostate-cancer
#9
Sebastian L Hofbauer, Beatrice Kittner, Andreas Maxeiner, Robin Heckmann, Maximillian Reimann, Laura Wiemer, Patrick Asbach, Matthias Haas, Tobias Penzkofer, Carsten Stephan, Frank Friedersdorff, Florian Fuller, Kurt Miller, Hannes Cash
PURPOSE: The second version of the Prostate Imaging Reporting and Data System (PI-RADSv2) was introduced in 2015 to standardize the interpretation and reporting of multiparametric prostate magnetic resonance imaging (mpMRI). Recently, low cancer detection rates (CDR) for PI-RADSv2 category 4 lesions were reported. Therefore the aim of the study was to evaluate the CDR of PI-RADSv2 in a large prospective cohort. METHODS: The study included 704 consecutive men with primary or prior negative biopsies who underwent MRI/ultrasound fusion-guided targeted biopsy (TB) and 10-core systematic prostate biopsy (SB) between September 2015 and May 2017...
May 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29733837/multiparametric-mri-ultrasound-fusion-prostate-biopsy-are-two-biopsy-cores-per-mri-lesion-required
#10
P Dimitroulis, R Rabenalt, A Nini, A Hiester, I Esposito, L Schimmöller, G Antoch, P Albers, C Arsov
PURPOSE: For multiparametric MRI/Ultrasound fusion prostate biopsy (FUSBx) the number of taken biopsy cores is arbitrary established by urologists. Moreover, general consensus on the number of biopsy cores to be obtained from a single MRI-lesion is lacking. Therefore, we aimed to evaluate the feasibility of obtaining only one biopsy core per MRI-lesion. MATERIALS AND METHODS: We retrospectively evaluated 2128 biopsy cores of 1064 prostatic lesions (two cores per lesion) in 418 patients regarding prostate cancer (PCa) detection (histology) and Gleason score (GS) of the first biopsy core (FBC) compared to the second biopsy core (SBC)...
May 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29732281/imaging-for-the-selection-and-monitoring-of-men-on-active-surveillance-for-prostate-cancer
#11
REVIEW
Maria C Velasquez, Nachiketh Soodana Prakash, Vivek Venkatramani, Bruno Nahar, Sanoj Punnen
Traditional prostate imaging is fairly limited, and only a few imaging modalities have been used for this purpose. Until today, grey scale ultrasound was the most widely used method for the characterization of the prostatic gland, however its limitations for prostate cancer (PCa) detection are well known and hence ultrasound is primarily used to localize the prostate and facilitate template prostate biopsies. In the past decade, multiparametric magnetic resonance imaging (mpMRI) of the prostate has emerged as a promising tool for the detection of PCa...
April 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29732206/patient-experience-after-transperineal-template-prostate-biopsy-compared-to-prior-transrectal-ultrasound-guided-prostate-biopsy
#12
Nikita R Bhatt, Kieran Breen, Usman M Haroon, Muhammad Akram, Hugh D Flood, Subhasis K Giri
Introduction: Transperineal template prostate biopsy (TTPB) is reported to have higher cancer detection and lower complication rate compared to transrectal ultrasound guided prostate biopsy (TRUSPB).However, there is no report of the same patient's experience with both types of biopsy.To compare the patient reported experience in the same cohort of patients who underwent both TRUSPB and TTPB, using validated questionnaires. Material and methods: We retrospectively utilised the Patient Reported Outcome Methods (PROM) tool validated for TRUSPB and the International Index of Erectile Function (IIEF-5) questionnaire to collect longitudinal data at follow-up in the same cohort of patients who underwent both TTPB and TRUSPB between January 2015 and February 2016...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29730256/the-role-of-imaging-in-prostate-cancer-care-pathway-novel-approaches-to-urologic-management-challenges-along-ten-imaging-touch-points
#13
REVIEW
Qian Li, Feixiang Xiang, Xueying Lin, Joseph R Grajo, Long Yang, Yufeng Xu, Yu Duan, Urvi Vyas, Mukesh Harisinghani, Umar Mahmood, Anthony E Samir
We map out a typical prostate cancer care pathway through discussion of updates on modern imaging. Multiparametric MRI (mpMRI) is the most sensitive and specific imaging tool for diagnosis and local staging, transrectal ultrasound remains the most widely used technique for prostate biopsy guidance, CT and bone scan are useful in initial staging and recurrence detection. Novel imaging techniques in ultrasound elastography and mpMRI allow for increased lesion detection sensitivity and have the potential to enhance biopsy, while the development of new PET radiotracers has great promise for improved detection of local and metastatic disease in patients with biochemical recurrence...
May 3, 2018: Urology
https://www.readbyqxmd.com/read/29728517/a-first-in-man-study-of-68-ga-nanocolloid-pet-ct-sentinel-lymph-node-imaging-in-prostate-cancer-demonstrates-aberrant-lymphatic-drainage-pathways
#14
Jacki A Doughton, Michael S Hofman, Peter Eu, Rodney J Hicks, Scott G Williams
Purpose: To assess feasibility, safety and utility of a novel 68 Ga-nanocolloid radio-tracer with PET-CT lymphoscintigraphy for identification of sentinel lymph nodes (SLN). Methods: Pilot study of patients from a tertiary cancer hospital who required insertion of gold fiducials for prostate cancer radiation therapy. Participation did not affect cancer management. Ultrasound-guided transperineal intra-prostatic injection of PET tracer (iron oxide nanocolloid labelled with gallium-68) after placement of fiducials...
May 4, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29725946/spectrophotometric-photodynamic-diagnosis-of-prostate-cancer-cells-excreted-in-voided-urine-using-5-aminolevulinic-acid
#15
Yasushi Nakai, Makito Miyake, Satoshi Anai, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Sayuri Onisi, Nobumichi Tanaka, Kiyohide Fujimoto
To evaluate the feasibility of photodynamic diagnosis using 5-aminolevulinic acid (PDD-ALA) for detection of prostate cancer (PCa) cells in urine samples after prostate massage in patients who were suspected to have PCa. One hundred and eighty-nine patients with abnormal digital rectal examination and/or an elevated prostate-specific antigen (PSA) level who underwent initial prostate biopsy were recruited. After prostate massage, the first 60 mL of voided urine was collected. For PDD-ALA, 50 mL was used. The rest of collected urine was used for polymerase chain reaction (PCR) of PSA and glyceraldehyde 3-phosphate dehydrogenase (GAPDH)...
May 4, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29723459/-clinicopathological-features-of-primary-seminal-vesicle-adenocarcinoma-a-report-of-4-cases-and-review-of-the-literature
#16
Jia-Ning Guo, Hui Li, Zhan-Dong Hu, En-Li Liang, Ji-Wu Chang
Objective: To investigate the clinicopathological characteristics, diagnosis, and treatment of primary seminal vesicle adenocarcinoma (SVAC). METHODS: We analyzed the clinical data and clinicopathological characteristics of 4 cases of primary SVAC treated in the Department of Urology of the Second Hospital of Tianjin Medical University and reviewed relevant literature. RESULTS: All the 4 patients were treated by open radical resection of the seminal vesicle and prostate and pathologically diagnosed with SVAC...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29723457/-one-puncture-one-needle-trus-guided-prostate-biopsy-for-prevention-of-postoperative-infections
#17
Xiao-Fu Qiu, Guo-Sheng Yang, Bo-Te Chen, Li Ma
Objective: To explore the feasibility and effectiveness of "one-puncture one-needle" transrectal ultrasound (TRUS)-guided prostate biopsy in the prevention of postoperative infections. METHODS: We retrospectively analyzed the clinical data about "one-puncture one-needle" (the observation group) and "one-person one-needle" (the control group) TRUS-guided prostate biopsy performed in the Second People's Hospital of Guangdong Province from January 2005 to December 2015, and compared the incidence rates of puncture-related infection between the two strategies...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29721063/photoacoustic-imaging-as-an-early-biomarker-of-radio-therapeutic-efficacy-in-head-and-neck-cancer
#18
Laurie J Rich, Austin Miller, Anurag K Singh, Mukund Seshadri
The negative impact of tumor hypoxia on radiotherapeutic efficacy is well recognized. However, an easy to use, reliable imaging method for assessment of tumor oxygenation in routine clinical practice remains elusive. Photoacoustic imaging (PAI) is a relatively new imaging technique that utilizes a combination of light and ultrasound (US) to enable functional imaging of tumor hemodynamic characteristics in vivo . Several clinical trials are currently evaluating the utility of PAI in cancer detection for breast, thyroid, and prostate cancer...
2018: Theranostics
https://www.readbyqxmd.com/read/29719325/incremental-value-of-68-gallium-prostate-specific-membrane-antigen-positron-emission-tomography-computed-tomography-in-patients-with-abnormal-prostate-specific-antigen-and-benign-transrectal-ultrasound-biopsy
#19
Manoj Gupta, Partha Sarathi Choudhury, Sudhir Rawal, Gurudutt Gupta
Introduction: Bladder outlet obstruction due to prostate enlargement is a common health problem in male and frequently investigated with prostate-specific antigen (PSA) and transrectal ultrasound (TRUS). TRUS-guided biopsy is critical to differentiate benign prostatic hyperplasia (BPH) or prostate cancer (PCa) even though it has been associated with false negative with reported 3%-16% incidence of PCa in BPH specimens. Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT), a targeted molecular imaging for PCa, has showed promising results in recurrence and staging...
April 2018: Urology Annals
https://www.readbyqxmd.com/read/29715138/comparing-image-guided-targeted-biopsies-to-radical-prostatectomy-specimens-for-accurate-characterization-of-the-index-tumor-in-prostate-cancer
#20
Francesco Porpiglia, Stefano DE Luca, Enrico Checcucci, Diletta Garrou, Matteo Manfredi, Fabrizio Mele, Angela Pecoraro, Roberto Passera, Enrico Bollito, Cristian Fiori
AIM: To evaluate the accuracy of multiparametric magnetic resonance-transrectal ultrasound fusion targeted biopsy (TBx) in the characterization of the index tumor, as confirmed by association with radical prostatectomy (RP) specimens. PATIENTS AND METHODS: A total of 152 patients with TBx-confirmed prostate cancer (PCa) underwent robot-assisted RP. Stained whole-mount histological sections were used as the reference standard. All lesions with a volume >0.5 ml and/or pathological Gleason score (GS) >6 were defined as clinically significant PCa...
May 2018: Anticancer Research
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