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https://www.readbyqxmd.com/read/29907442/predictors-of-mitral-annulus-enlargement-a-real-time-three-dimensional-transesophageal-study
#1
V Boilève, J Dreyfus, D Attias, A Scheuble, I Codogno, E Brochet, A Vahanian, D Messika-Zeitoun
BACKGROUND: Mitral annulus (MA) enlargement can be observed in various cardiac conditions but respective influence of left atrial (LA) and left ventricle (LV) size remained unclear. METHODS: In 120 patients who underwent a clinically indicated 3D-transesophageal-echocardiography, 30 atrial fibrillation (AF), 30 secondary mitral regurgitation (SMR), 30 primary myxomatous mitral regurgitation (PMR) and 30 mitral stenosis (MS), we evaluated the association between MA area (MA-area) and LA volume (LAvol) measured using the biplane area-length method, end-diastolic (LVEDV) and end-systolic (LVESV) volumes measured using the biplane Simpson method...
June 5, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29905827/predictors-of-residual-tricuspid-regurgitation-after-percutaneous-closure-of-atrial-septal-defect
#2
Martina Nassif, Frank van der Kley, Mohammad Abdelghani, Deborah N Kalkman, Rianne H A C M de Bruin-Bon, Berto J Bouma, Martin J Schalij, David R Koolbergen, Jan G P Tijssen, Barbara J M Mulder, Robbert J de Winter
Aims: Functional tricuspid regurgitation (TR) associated with atrial septal defects (ASDs) is frequently present due to right-sided volume-overload. Tricuspid valve (TV) repair is often considered in candidates for surgical ASD closure, and percutaneous TV repair is currently under clinical investigation. In this study, we develop a prediction model to identify patients with residual moderate/severe TR after percutaneous ASD closure. Methods and results: In this observational study, 172 adult patients (26% male, age 49 ± 17 years) with successful percutaneous ASD closure had pre- and post-procedural echocardiography...
June 13, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29904583/recent-advances-in-transcatheter-management-of-pulmonary-regurgitation-after-surgical-repair-of-tetralogy-of-fallot
#3
REVIEW
Matthew I Jones, Shakeel A Qureshi
Surgical repair of tetralogy of Fallot (ToF) in childhood is associated with generally good outcomes, and almost all children can be expected to survive until adulthood. However, significant pulmonary regurgitation leading to progressive right ventricular dilatation is common in teenagers or young adults because of the nature of the surgical intervention. In patients whose repair included placement of a right ventricle to pulmonary artery conduit, it has been possible to place a stented valve within the conduit to treat this...
2018: F1000Research
https://www.readbyqxmd.com/read/29904483/pulmonary-venous-varix-associated-with-mitral-regurgitation-mimicking-a-mediastinal-mass-a-case-report-and-review-of-the-literature
#4
Dana AlNuaimi, Reem AlKetbi, Usama AlBastaki, Claude Pierre-Jerome, Ebrahim Ahmad Ebrahim
Pulmonary vein varix is an unusual cause of a mediastinal mass on a chest radiograph. It may be found as an isolated malformation or as a sequela of pulmonary venous hypertension. We encountered a case presenting with left hemiparesis and a past medical history of rheumatic heart disease. The chest radiograph revealed a well-defined mediastinal mass that turned out to be a hugely dilated pulmonary vein on contrast enhanced computed tomography of the chest. The computed tomography of the brain and upper abdomen revealed bilateral cerebral infarction and splenic infarction...
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29904131/quantitative-study-of-abdominal-blood-flow-patterns-in-patients-with-aortic-dissection-by-4-dimensional-flow-mri
#5
Dongting Liu, Zhanming Fan, Yu Li, Nan Zhang, Zhonghua Sun, Jing An, Aurélien F Stalder, Andreas Greiser, Jiayi Liu
The purpose of this study is to evaluate the hemodynamic characteristics of the true lumen (TL) and the false lumen (FL) in 16 patients with aortic dissection (AD) using 4D flow magnetic resonance imaging (MRI) and thoracic and abdominal computed tomography (CT) angiography. The quantitative parameters that were measured in the TL and FL included velocity and flow. The mean area and regurgitant fraction of the TL were significantly lesser at all four levels (p < 0.05); the average through-plane velocity, peak velocity magnitude, average net flow, peak flow, and net forward volume in the TL were considerably higher (p < 0...
June 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29903680/-non-infective-endocarditis
#6
A Le Bot, P Jégo, E Donal, E Flécher, M Revest, P Tattevin
Non-infective endocarditis, also referred to as non-bacterial thrombotic endocarditis, represent a wide range of rare pathologies, often severe. This review gathered the data available in the literature, to decipher the major information collected on the pathophysiology, the diagnosis and the treatment of these heterogeneous diseases, often misdiagnosed. Characteristics of non-infective endocarditis are similar to infective endocarditis in terms of valvular lesions (mostly left-sided, with regurgitations and vegetations), and their complications (embolism)...
June 11, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29903514/dobutamine-stress-echocardiography-in-pulmonary-arterial-hypertension
#7
Stefano Ghio, Federico Fortuni, Alessandra Greco, Annalisa Turco, Carlo Lombardi, Laura Scelsi, Claudia Raineri, Benedetta Matrone, Eleonora Vullo, Stefania Guida, Roberto Badagliacca, Luigi Oltrona Visconti
BACKGROUND: There is a growing interest in exploring the concept of right ventricular functional reserve in patients with pulmonary arterial hypertension. However, it is still unclear how it should be assessed. Aim of the study was to investigate the determinants of the changes in cardiac output and in pulmonary pressure during dobutamine stress echocardiography in pulmonary arterial hypertension. METHODS: Low-dose dobutamine stress echocardiography was performed in 55 patients and 28 controls...
June 8, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29902642/diagnosis-and-treatment-of-rumination-syndrome
#8
Magnus Halland, John Pandolfino, Elizabeth Barba
Rumination syndrome is a functional gastrointestinal disorder characterized by effortless post-prandial regurgitation. The disorder appears uncommon, although only limited epidemiological data are available. Awareness of the characteristic symptoms is essential for recognizing the disorder, and thus avoiding the long delay in diagnosis which many patients experience. Whilst objective testing by post-prandial esophageal high resolution impedance manometry is available in select referral centers, a clinical diagnosis can be made in most patients...
June 11, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29902273/finite-element-analysis-of-annuloplasty-and-papillary-muscle-relocation-on-a-patient-specific-mitral-regurgitation-model
#9
Fanwei Kong, Thuy Pham, Caitlin Martin, John Elefteriades, Raymond McKay, Charles Primiano, Wei Sun
OBJECTIVES: Functional mitral regurgitation (FMR) is a significant complication of left ventricle (LV) dysfunction associated with poor prognosis and commonly treated by undersized ring annuloplasty. This study aimed to quantitatively simulate the treatment outcomes and mitral valve (MV) biomechanics following ring annulopalsty and papillary muscle relocation (PMR) procedures for a FMR patient. METHODS: We utilized a validated finite element model of the left heart for a patient with severe FMR and LV dilation from our previous study and simulated virtual ring annuloplasty procedures with various sizes of Edwards Classic and GeoForm annuloplasty rings...
2018: PloS One
https://www.readbyqxmd.com/read/29902265/clinical-use-of-submaximal-treadmill-exercise-testing-and-assessments-of-cardiac-biomarkers-nt-probnp-and-ctni-in-dogs-with-presymptomatic-mitral-regurgitation
#10
Leona Wall, Annika Mohr, Florenza Lüder Ripoli, Nayeli Schulze, Camila Duarte Penter, StephanOscar Hungerbuehler, Jan-Peter Bach, Karin Lucas, Ingo Nolte
Exercise intolerance is the first symptom of heart disease. Yet an objective and standardised method in canine cardiology to assess exercise capacity in a clinical setting is lacking. In contrast, exercise testing is a powerful diagnostic tool in humans, providing valuable information on prognosis and impact of therapeutic intervention. To investigate whether an exercise test reveals differences between dogs with early stage mitral regurgitation (MR) and dogs without cardiac disease, 12 healthy beagles (healthy group, HG) and 12 dogs with presymptomatic MR (CHIEF B1 / B2, patient group, PG) underwent a six-stage submaximal exercise test (ET) on a motorised treadmill...
2018: PloS One
https://www.readbyqxmd.com/read/29901810/on-x-mitral-valve-replacement-a-single-centre-experience-in-318-patients
#11
Giacomo Murana, Jacopo Alfonsi, Carlo Savini, Carlo Mariani, Giuditta Coppola, Valeria Lo Coco, Emanuele Pilato, Davide Pacini, Roberto Di Bartolomeo
OBJECTIVES: If mitral valve repair is not feasible, mitral valve replacement remains the only option. Based on our overall experience with the On-X mitral valve, the aim of this study was to investigate early and late outcomes after mitral valve replacement using this latest generation prosthesis. METHODS: From 1998 to 2016, 600 patients received an On-X prosthesis in the mitral position. Of them, we excluded all patients who had combined aortic procedures and retrospectively analysed 318 consecutive patients who had a mitral valve replacement...
June 12, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29899656/robotic-assisted-transthoracic-esophageal-diverticulectomy
#12
Bengi Balci, Gizem Kilinc, Bülent Calik, Gökhan Akbulut
Introduction: Esophageal diverticulum is a rare entity with symptoms that include dysphagia, halitosis, chest pain, and regurgitation. Indications for surgery include the presence of any of these symptoms and a diverticulum larger than 3 cm because of the increased risk of malignancy and aspiration. Treatment is open or minimally invasive surgery performed from the transhiatal or transthoracic approach. Case Description: Three patients were investigated by esophagogastroduodenoscopy, esophageal manometry, and computed tomography and were given the diagnosis of epiphrenic diverticulum of the esophagus...
April 2018: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/29898465/follow-up-of-the-novel-free-margin-running-suture-technique-for-mitral-valve-repair
#13
Alfonso Agnino, Alberto Maria Lanzone, Andrea Albertini, Amedeo Anselmi
The free margin running suture (FMRS) is a novel technique for nonresection correction of degenerative mitral regurgitation. It was employed in 37 minimally invasive mitral repair cases. We performed a retrospective collection of in-hospital data and a clinical/echocardiographic follow-up. All patients were discharged with none or mild mitral regurgitation, except one who had mild-to-moderate (2+) regurgitation. At follow-up (average: 2.1 years), all patients were alive; there were no instances of recurrent regurgitation, one case of 2+ regurgitation, and no valve-related complications...
June 13, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29897441/left-ventricular-assist-device-implantation-with-and-without-concomitant-tricuspid-valve-surgery-a-systematic-review-and-meta-analysis
#14
Kevin M Veen, Rahatullah Muslem, Osama I Soliman, Kadir Caliskan, Marit E A Kolff, Dagmar Dousma, Olivier C Manintveld, Ozcan Birim, Ad J J C Bogers, Johanna J M Takkenberg
OBJECTIVES: Moderate-to-severe tricuspid regurgitation is common in end-stage heart disease and is associated with an impaired survival after left ventricular assist device (LVAD) surgery. Controversy remains whether concomitant tricuspid valve surgery (TVS) during LVAD implantation is beneficial. We aimed to provide a contemporary overview of outcomes in patients who underwent LVAD surgery with or without concomitant TVS. METHODS: A systematic literature search was performed for articles published between January 2005 and March 2017...
April 20, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29897435/mitral-valve-posterior-leaflet-reconstruction-using-extracellular-matrix-an-acute-porcine-study
#15
Marcell J Tjørnild, Søren N Skov, Karen B Poulsen, Mona Sharghbin, Leila L Benhassen, Lisa Carlson Hanse, Farhad Waziri, Diana M Røpcke, Sten L Nielsen, J Michael Hasenkam
OBJECTIVES: To investigate mitral valve posterior leaflet and subvalvular reconstruction using a 2-ply small intestinal submucosal extracellular matrix sheet. METHODS: Mitral valve posterior leaflet and subvalvular reconstruction was characterized in an acute 80-kg porcine model with 7 pigs acting as their own controls. The characterization was based on pressure catheter measurements of pressure differences to identify mitral regurgitation, stenosis and systolic anterior motion...
April 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29897254/the-relationship-between-primary-acquired-nasolacrimal-duct-obstruction-and-gastroesophageal-reflux
#16
Naser Owji, Mohammad Radaei, Behzad Khademi
Purpose/Aim of the study: To evaluate if there is any relationship or coincidence between Gastroesophageal reflux disease (GERD) and primary acquired nasolacrimal duct obstruction (PANDO). MATERIAL AND METHODS: We enrolled 180 patients with primary acquired nasolacrimal duct obstruction, confirmed by positive regurgitation on sac squeezing or by irrigation test. In the control group any patient with lacrimal drainage obstruction was excluded. For diagnosis of gasteroesophgal reflux we used a (Gerd Q) questionnaire by R...
June 13, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29897149/atrial-involvement-in-arrhythmogenic-right-ventricular-cardiomyopathy-patients-referred-for-ventricular-arrhythmias-ablation
#17
Lingmin Wu, Jingru Bao, Erpeng Liang, Siyang Fan, Lihui Zheng, Zhongpeng Du, Gang Chen, Ligang Ding, Shu Zhang, Yan Yao
BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable myocardium disorder that predominantly affects the ventricle. Little is known about atrial involvement. This study aimed to assess atrial involvement, especially the role of genotype on atrium in ARVC. METHODS: The incidence, characterization and predictors of atrial involvement were investigated. Nine known ARVC-causing genes were screened and the correlation between genotype and atrial involvement was assessed...
June 13, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29897014/future-technology-of-mitral-valve-repair-and-replacement-for-mitral-valve-disease
#18
Kelly Kohorst, Mias Pretorius
Mitral regurgitation is the most common valvular disease and significant (moderate/severe) mitral regurgitation is found in 2.3% of the population older than 65 years. New transcatheter minimally invasive technologies are being developed to address mitral valve disease in patients deemed too high a risk for conventional open-heart surgery. There are several features of the mitral valve (saddle-shaped noncalcified annulus with irregular leaflet geometry) that make a transcatheter approach to repair or replacing the valve more challenging compared with the aortic valve...
June 1, 2018: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29897008/interventional-echocardiography-of-the-mitral-valve-what-the-interventionist-wants-to-know
#19
Ludmil Mitrev, Nayan Desai, Ahmed Awad, Sajjad Sabir
The past 2 decades have seen a proliferation of transcatheter mitral valve (MV) therapies, which are less invasive and distinct from surgical MV repair or replacement. The commonly used MV transcatheter therapies include (1) percutaneous mitral balloon commissurotomy (PMBC) for rheumatic mitral stenosis; (2) edge-to-edge repair with the MitraClip for mitral regurgitation; (3) valve-in-valve implantation in bioprosthetic MV, native MV, or mitral ring; and (4) closure of paravalvular leaks (PVLs). This article will focus on the use of echocardiography in the diagnosis, patient selection, procedural guidance, and postprocedural follow-up for PMBC, with notes on the role of transesophageal echocardiography in transcatheter interventions for prosthetic valve degeneration and PVL closure...
June 1, 2018: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29896861/galectin-3-and-st2-as-predictors-of-therapeutic-success-in-high-risk-patients-undergoing-percutaneous-mitral-valve-repair-mitraclip
#20
Oliver Dörr, Claudia Walther, Christoph Liebetrau, Till Keller, Thomas Sommer, Niklas Boeder, Matthias Bayer, Pascal Bauer, Helge Möllmann, Luise Gaede, Christian Troidl, Sandra Voss, Timm Bauer, Christian W Hamm, Holger Nef
BACKGROUND: Percutaneous mitral valve repair (PMVR) is an interventional treatment option in patients with severe mitral regurgitation (MR) who have a high risk for open-heart surgery. Currently, there is limited information about predictors of procedural success after PMVR. Galectin-3 (Gal-3) and ST2 induce fibrotic alterations in severe MR and heart failure. The aim of the present study was to examine the predictive value of Gal-3 and ST2 as specific indicators of therapeutic success in high-risk patients undergoing PMVR...
June 12, 2018: Clinical Cardiology
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