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https://www.readbyqxmd.com/read/29688145/use-of-echocardiography-at-diagnosis-and-detection-of-acute-cardiac-disease-in-youth-with-systemic-lupus-erythematosus
#1
J C Chang, A M Knight, R Xiao, L M Mercer-Rosa, P F Weiss
Objectives There are no guidelines on the use of echocardiography to detect cardiac manifestations of childhood-onset systemic lupus erythematosus (SLE). We quantify the prevalence of acute cardiac disease in youth with SLE, describe echocardiogram utilization at SLE diagnosis, and compare regional echocardiogram use with incident cardiac diagnoses. Methods Using the Clinformatics® DataMart (OptumInsight, Eden Prairie, MN) de-identified United States administrative database from 2000 to 2013, we identified youth ages 5-24 years with new-onset SLE (≥3 ICD-9 SLE codes 710...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29665445/acute-kidney-injury-during-treatment-with-high-dose-cloxacillin-a-report-of-23-cases-and-literature-review
#2
Aurélie Lavergne, Cécile Vigneau, Elisabeth Polard, Louise Triquet, Nathalie Rioux-Leclercq, Pierre Tattevin, Léonard Golbin
BACKGROUND: International guidelines recommend high-dose cloxacillin for endocarditis or osteoarticular infections due to meticillin-susceptible staphylococci. However, data on the tolerability of these regimens are scarce. METHODS: We used the computerized registry of suspected drug-related adverse events in our institution. Cases of acute kidney injury (AKI), as defined by KDIGO, in patients receiving high-dose cloxacillin, were retrospectively reviewed. Data were collected from medical charts on a standardized questionnaire...
April 14, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29663969/adherence-to-infective-endocarditis-prevention-guidelines-by-israeli-dentists-who-treat-children
#3
Nili Tickotsky, Sarit Faibis, Geula Gellman, Michael Shoshani, Yael Kutiner, Moti Moskovitz
PURPOSE: To examine the rate of adherence of Israeli dentists who treat children and their rate of adherence, in 2010-2011 and in 2016, to changes made to the 2008 American Heart Association (AHA) guidelines for endocarditis prevention. METHODS: A questionnaire on adherence to AHA guidelines was handed out in two consecutive continuing education courses in 2010-2011 and again in 2016. Data were analyzed using student's t test, chi-square, and analysis of variance...
January 15, 2018: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/29642989/cardiogenic-causes-of-fever
#4
Jan Smid, Maximilian Scherner, Oliver Wolfram, Thomas Groscheck, Jens Wippermann, Rüdiger C Braun-Dullaeus
BACKGROUND: Persistent fever of unknown cause is only rarely of cardiac origin, but heart disease must be considered in the differential diagnosis. Aside from endocarditis, pericarditis and various other conditions may be responsible. METHODS: This review is based on pertinent articles retrieved by a selective search in PubMed and Google Scholar employing the term "fever" in combination with "myocardial infarction," "pericarditis," "endocarditis," and "postcardiac injury," with additional consideration of current cardiological guidelines...
March 23, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29629256/european-society-of-cardiology-proposed-diagnostic-echocardiographic-algorithm-in-elective-patients-with-clinical-suspicion-of-infective-endocarditis-diagnostic-yield-and-prognostic-implications-in-clinical-practice
#5
Andrea Barbieri, Francesca Mantovani, Roberta Lugli, Francesca Bursi, Matteo Fabbri, Ylenia Bartolacelli, Marcella Manicardi, Guglielmo Stefanelli, Cristina Mussini, Giuseppe Boriani
Background: Echocardiography plays a central role in diagnosing infective endocarditis (IE). Accordingly, the European Society of Cardiology (ESC) has proposed a diagnostic echocardiographic algorithm. However, new studies are still needed to evaluate the degree of implementation of these guidelines in clinical practice and their consequences on incidence and prognosis of IE. Aim: This study aims to investigate the diagnostic yield of the ESC proposed echocardiographic algorithm in patients with suspected IE...
January 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29581048/what-risk-of-endocarditis-is-low-enough-to-justify-the-omission-of-transoesophageal-echocardiography-in-staphylococcus-aureus-bacteraemia-a-narrative-review
#6
REVIEW
George S Heriot, Steven Y C Tong, Allen C Cheng, Danny Liew
BACKGROUND: recent criteria able to identify patients with Staphylococcus aureus bacteraemia (SAB) who are at very low risk of endocarditis raise the question of whether transoesophageal echocardiography (TOE) is appropriate for these patients. AIMS: to estimate the probability of occult endocarditis complicating SAB below which a TOE-guided treatment strategy no longer offers the best 180-day survival), and examine the key uncertainties affecting this result. SOURCES: Estimates of the parameters required to calculate the Pauker-Kassirer testing threshold were identified from studies published prior to 1 June 2017 using a composite search strategy involving a systematic search for relevant controlled trials and guidelines followed by a non-systematic iterative search of the observational literature...
March 23, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29563819/a-case-of-brucella-melitensis-endocarditis-in-a-patient-with-cardiovascular-implantable-electronic-device
#7
Wasl Al-Adsani, Ali Ahmad, Mohammad Al-Mousa
Background: Brucellosis is a bacterial infection, caused by the nonmotile gram-negative aerobic coccobacilli. The clinical manifestation of brucellosis is variable, ranging from mild disease to severe disease. The gold standard test to confirm the diagnosis of brucellosis is assaying blood, bone marrow, or other body fluids or by tissue culture. Preferred first-line treatment in adults with uncomplicated, nonlocalized disease consists of doxycycline-aminoglycoside combination. The recommended duration of treatment is 6 weeks...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29558307/cerebral-microbleeds-imaging-and-clinical-significance
#8
Sven Haller, Meike W Vernooij, Joost P A Kuijer, Elna-Marie Larsson, Hans Rolf Jäger, Frederik Barkhof
Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility-weighted (SW) imaging. CMBs are detected with increasing frequency because of the more widespread use of high magnetic field strength and of newer dedicated MR imaging techniques such as three-dimensional gradient-echo T2*-weighted and SW imaging. The imaging appearance of CMBs is mainly because of changes in local magnetic susceptibility and reflects the pathologic iron accumulation, most often in perivascular macrophages, because of vasculopathy...
April 2018: Radiology
https://www.readbyqxmd.com/read/29526448/s-aureus-endocarditis-clinical-aspects-and-experimental-approaches
#9
REVIEW
V Hoerr, M Franz, M W Pletz, M Diab, S Niemann, C Faber, T Doenst, P C Schulze, S Deinhardt-Emmer, B Löffler
Infective endocarditis (IE) is a life-threatening disease, caused by septic vegetations and inflammatory foci on the surface of the endothelium and the valves. Due to its complex and often indecisive presentation the mortality rate is still about 30%. Most frequently bacterial microorganisms entering the bloodstream are the underlying origin of the intracardiac infection. While the disease was primarily restricted to younger patients suffering from rheumatic heart streptococci infections, new at risk categories for Staphylococcus (S...
February 21, 2018: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/29516497/platelet-transfusion-is-not-associated-with-increased-mortality-or-morbidity-in-patients-undergoing-cardiac-surgery
#10
Slavisa Ninkovic, Zoe McQuilten, Robert Gotmaker, Andrew E Newcomb, Merrole F Cole-Sinclair
BACKGROUND: Transfusion of platelets is common in cardiac surgery, and while there are guidelines for their use, there are concerns about potential risks. We aimed to assess the impact of platelet transfusion on mortality, thrombosis, and infection in this patient group. STUDY DESIGN AND METHODS: A retrospective cohort study of all patients at St Vincent's Hospital Melbourne who underwent a first cardiac surgery procedure from June 2001 to June 2014 was conducted...
May 2018: Transfusion
https://www.readbyqxmd.com/read/29496402/cardiac-18-f-fdg-pet-ct-procedure-for-the-diagnosis-of-prosthetic-endocarditis-and-intracardiac-devices
#11
S Aguadé Bruix, A Roque Pérez, H Cuéllar Calabria, M N Pizzi
Infective endocarditis (IE) is a serious condition with a poor prognosis, its mortality unchanged significantly despite diagnostic and therapeutic advances in the last 30years. The diagnostic ability of the modified Duke criteria in prosthetic endocarditis and/or devices does not exceed 50%, so new tools are necessary for the diagnosis of this entity in this context. The 18 F-FDG PET/CTA combines a highly sensitive technique to detect inflammatory-infectious activity with a technique with high anatomical resolution to assess the structural lesions associated with endocarditis...
May 2018: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/29492935/trends-in-infective-endocarditis
#12
Khadija Mzoughi, Ihsen Zairi, Samia Ben Hamida, Sofien Kamoun, Fethia Ben Moussa, Sana Fennira, Sondos Kraiem
INTRODUCTION: Infectious endocarditis (IE) is a rare disease with a high mortality. In 2009, the European society of cardiology restricted antibiotic prophylaxis to a smaller number of cardiac conditions with very high risk for IE. Did these changes in the guidelines have an impact on the epidemiological and bacteriological profile of IE? AIM: The main aim of our work was to study the evolution of the microbiological profile of IE from 1991 to 2016. METHODS: We realized an analytic retrospective study comparing two groups: group 1 included patients admitted for a certain IE before September 2009 and group 2 those admitted after that date...
April 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29468436/repair-of-infected-mitral-valves-what-have-we-learned
#13
REVIEW
Yu-Ning Hu, Song Wan
Infective endocarditis (IE) is associated with high mortality and morbidity and requires surgical intervention in about half of all patients. Mitral valve repair (MVrep) is reported to achieve better results than mitral valve replacement because the insertion of a prosthesis during active infection is avoided. However, MVrep in active IE is complicated and no definitive guidelines have been compiled. The current study reviews the literature from 2000 to 2016 and summarizes the surgical details of MVrep for IE...
February 21, 2018: Surgery Today
https://www.readbyqxmd.com/read/29462176/outcome-of-enterococcus-faecalis-infective-endocarditis-according-to-the-length-of-antibiotic-therapy-preliminary-data-from-a-cohort-of-78-patients
#14
Juan M Pericàs, Carlos Cervera, Asunción Moreno, Cristina Garcia-de-la-Mària, Manel Almela, Carles Falces, Eduard Quintana, Bàrbara Vidal, Jaume Llopis, David Fuster, Carlos A Mestres, Francesc Marco, Jose M Miró
BACKGROUND: International guidelines recommend 4 weeks of treatment with ampicillin plus gentamicin (A+G) for uncomplicated native valve Enterococcus faecalis infective endocarditis (EFIE) and 6 weeks in the remaining cases. Ampicillin plus ceftriaxone (A+C) is always recommended for at least 6w, with no available studies assessing its suitability for 4w. We aimed to investigate differences in the outcome of EFIE according to the duration (4 versus 6 weeks) of antibiotic treatment (A+G or A+C)...
2018: PloS One
https://www.readbyqxmd.com/read/29459947/association-of-vegetation-size-with-embolic-risk-in-patients-with-infective-endocarditis-a-systematic-review-and-meta-analysis
#15
Divyanshu Mohananey, Ashley Mohadjer, Gosta Pettersson, Jose Navia, Steven Gordon, Nabin Shrestha, Richard A Grimm, L Leonardo Rodriguez, Brian P Griffin, Milind Y Desai
Importance: Infective endocarditis is a life-threating condition with annual mortality of as much as 40% and is associated with embolic events in as many as 80% of cases. These embolic events have notable prognostic implications and have been linked to increased length of stay in intensive care units and mortality. A vegetation size greater than 10 mm has often been suggested as an optimal cutoff to estimate the risk of embolism, but the evidence is based largely on small observational studies...
April 1, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29452115/bioprosthetic-versus-mechanical-valve-replacement-for-infective-endocarditis-focus-on-recurrence-rates
#16
Nana Toyoda, Shinobu Itagaki, Henry Tannous, Natalia N Egorova, Joanna Chikwe
BACKGROUND: Consensus guidelines for prosthesis selection in infective endocarditis recommend bioprosthetic or mechanical valve replacement based on life expectancy and comorbidity. However, contemporary outcome data are limited to institution series. METHODS: The outcomes of 3,447 patients identified from mandatory discharge databases in California and New York states who had either primary isolated mitral (n=1603) or aortic (n=1,844) valve replacement for active endocarditis between 1998 and 2010, were compared according to whether they received bioprosthetic (n=1,673, 48...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29450741/utility-of-cardiac-computed-tomography-scanning-in-the-diagnosis-and-pre-operative-evaluation-of-patients-with-infective-endocarditis
#17
Jason R Sims, Nandan S Anavekar, Krishnaswamy Chandrasekaran, James M Steckelberg, Walter R Wilson, Bernard J Gersh, Larry M Baddour, Daniel C DeSimone
Transesophageal echocardiography (TEE) is the gold standard imaging study used in the diagnosis of infective endocarditis (IE). Computed tomography angiography (CTA) has undergone rapid advancement as a cardiac imaging technique and has previously shown promise in small non-randomized studies for evaluation of IE. We hypothesized that cardiac CTA would perform similarly to TEE in the detection of endocarditic lesions and that there would be no difference in clinical outcomes whether the coronary arteries were evaluated by CTA or invasive coronary angiography (ICA)...
February 15, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29430890/tricuspid-valve-replacement-results-of-an-orphan-procedure-which-is-the-best-prosthesis
#18
Dominik Wiedemann, Veronika Rupprechter, Julia Mascherbauer, Andreas Kammerlander, Bruno Mora, Kamen Dimitrov, Benedikt Weber, Martin Andreas, Günther Laufer, Alfred Kocher
BACKGROUND: Replacement of the tricuspid valve is uncommon. Prostheses specifically designed for the this position are not available. Bovine, porcine as well as mechanical valve prostheses are currently used, however, the most suitable prosthesis type has not been defined. METHODS: We retrospectively analyzed all consecutive patients who underwent tricuspid valve replacement (TVR) at the Medical University of Vienna from 1996 to 2014. Baseline patient characteristics, prosthesis type, and postoperative outcome data were collected...
February 8, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29404364/peri-procedural-antibiotic-prophylaxis-in-ventricular-septal-defect-a-case-study-to-re-visit-guidelines
#19
Nadish Garg, Mannu Nayyar, Rami N Khouzam, Salem A Salem, Devarshi Ardeshna
The current American Heart Association (AHA)/American College of Cardiology (ACC) guidelines do not recommend antibiotic prophylaxis for infective endocarditis (IE) in patients with acyanotic congenital valvular heart disease due to lack of any proven benefit and potential harm associated with antibiotics. As recognized by the guidelines, some acyanotic congenital heart disease, such as ventricular septal defects (VSDs), are associated with a high velocity jet and pose a greater risk of peri-procedural endocarditis...
January 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29357050/clinical-variation-in-the-use-of-echocardiography-in-staphylococcus-aureus-bacteraemia-a-multi-centre-cohort-study
#20
George S Heriot, Steven Y C Tong, Allen C Cheng, Irani Thevarajan, Michele R Levinson, Kumar Visvanathan, Danny Liew
The objective of this investigation was to assess whether between-hospital variation in echocardiography usage for patients with Staphylococcus aureus bacteraemia (SAB) is explained by differences in patients' pre-test probability of endocarditis. This was a retrospective cohort study at three neighbouring hospitals in Australia. Consecutive episodes of SAB were reviewed for the presence of three endocarditis risk factors (community onset, prolonged bacteraemia and the presence of an intracardiac prosthetic device) and the performance and results of all echocardiography studies within 30 days...
March 2018: European Journal of Clinical Microbiology & Infectious Diseases
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