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https://www.readbyqxmd.com/read/29330034/successful-treatment-of-a-penicillin-intermediate-and-ceftriaxone-resistant-granulicatella-adiacens-presumed-prosthetic-valve-endocarditis-with-vancomycin
#1
Bruce M Jones, Roby M Hersey, Irwin J Trestman, Christopher M Bland
Advancements in rapid diagnostics have helped to identify nutritionally variant streptococci (NVS) as an increasing cause of infective endocarditis. This case report highlights the challenges in susceptibility testing and the importance of appropriate empiric treatment for Granulicatella adiacens, as well as considerations for future practice guideline recommendations. Guidelines for treatment of IE caused by NVS are currently limited to patients with native valve disease. We present a patient with presumed prosthetic valve endocarditis caused by Granulicatella adiacens, with clinically relevant resistance to recommended first-line agents (penicillin and ceftriaxone), who was successfully treated with 8 weeks of intravenous (IV) vancomycin...
January 9, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29326959/use-of-antibiotic-prophylaxis-for-tooth-extractions-dental-implants-and-periodontal-surgical-procedures
#2
Katie J Suda, Heather Henschel, Ursula Patel, Margaret A Fitzpatrick, Charlesnika T Evans
Background: Guidelines for antibiotics prior to dental procedures for patients with specific cardiac conditions and prosthetic joints have changed, reducing indications for antibiotic prophylaxis. In addition to guidelines focused on patient comorbidities, systematic reviews specific to dental extractions and implants support preprocedure antibiotics for all patients. However, data on dentist adherence to these recommendations are scarce. Methods: This was a cross-sectional study of veterans undergoing tooth extractions, dental implants, and periodontal procedures...
January 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29324478/site-of-entry-and-surgical-timing-in-infective-endocarditis
#3
Francesco Bovenzi, Lucia Borelli, Lauro Cortigiani
: Infective endocarditis is the manifestation of the endocardial involvement during a systemic infectious process.The prognosis of this condition is still dismal, and the mortality associated with it remains high despite improvement in antimicrobial treatment. Antibiotic prophylaxis is still recommended only in high-risk cases, that is, procedures at high risk for inducing systemic bacteremia.It is important to provide an educational prophylaxis consisting of sound hygienic recommendations for the cleansing of the oral cavity, the skin, genital-urinary, and gastrointestinal systems...
January 10, 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29244073/incidence-of-infective-endocarditis-among-patients-considered-at-high-risk
#4
Lauge Østergaard, Nana Valeur, Nikolaj Ihlemann, Henning Bundgaard, Gunnar Gislason, Christian Torp-Pedersen, Niels Eske Bruun, Lars Søndergaard, Lars Køber, Emil Loldrup Fosbøl
Aims: Patients with prior infective endocarditis (IE), a prosthetic heart valve, or a cyanotic congenital heart disease (CHD) are considered to be at high risk of IE by guidelines. However, knowledge is sparse on the relative risk of IE between these three groups and compared controls. Methods and results: Using Danish nationwide registries (1996-2015), we identified all patients with prior IE, a prosthetic heart valve, or a complex CHD (defined as tetralogy of Fallot, truncus arteriosus, and transposition of great arteries) as well as matched control populations...
December 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29229070/infective-endocarditis-an-update-for-dental-surgeons
#5
REVIEW
Andrew Narendran Robinson, Paul Anantharajah Tambyah
Infective endocarditis (IE) is associated with significant morbidity and mortality. The prevention of infective endocarditis, for many years, has involved the identification of at risk patients undergoing medical or dental procedures and the use of pre-procedural antibiotic prophylaxis. However, evidence regarding the effectiveness of such measures is lacking while evidence is mounting for the adverse effects of inappropriate antibiotic use. International guidelines for antibiotic prophylaxis were amended, radically in some cases to reflect this...
December 2017: Singapore Dental Journal
https://www.readbyqxmd.com/read/29228242/mortality-risk-prediction-in-infective-endocarditis-surgery-reliability-analysis-of-specific-scores
#6
Laura Varela, Jose López-Menéndez, Ana Redondo, Edmundo Ricardo Fajardo, Javier Miguelena, Tomasa Centella, Miren Martín, Rafael Muñoz, Enrique Navas, Jose Luis Moya, Jorge Rodríguez-Roda
OBJECTIVES: We assessed the prognostic utility of risk scores in surgery for infective endocarditis (IE) to evaluate their reliability in mortality risk prediction. METHODS: An observational retrospective study was developed to include all patients who underwent surgery for active IE from 2002 to 2016. Classical and endocarditis-specific risk scores were calculated. RESULTS: A total of 180 patients were included in the study. The 30-day mortality rate was 26...
December 8, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29200087/rapid-explantation-of-rapid-deployment-sutureless-valve-in-case-of-acute-endocarditis-how-to-remove-safely-sutureless-perceval-s-prostheses
#7
Lorenzo Di Bacco, Steffen Pfeiffer, Theodor J M Fischlein, Giuseppe Santarpino
We report a case of infective endocarditis on a Perceval S aortic valve bioprosthesis, and we describe a feasible and useful technique that can help remove the infected valve. These maneuvers consist of an "x-movement" reached with the aid of anatomical forceps. The risk of infective endocarditis in patients with prosthetic valves is a well-known phenomena in cardiac surgery, and it can represent a life-threatening event in many cases. According to guidelines, an emergency surgical intervention is required in case of high risk of embolization, vegetation superior than 1 cm or acute cardiac failure secondary to the acute valve dysfunction...
November 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29174663/a-nationwide-survey-of-french-dentists-knowledge-and-implementation-of-current-guidelines-for-antibiotic-prophylaxis-of-infective-endocarditis-in-patients-with-predisposing-cardiac-conditions
#8
Alexandra Cloitre, Xavier Duval, Bruno Hoen, François Alla, Philippe Lesclous
OBJECTIVES: To prevent infective endocarditis in patients with predisposing cardiac conditions, antibiotic prophylaxis is recommended worldwide, except in the United Kingdom. To determine the relevance of this strategy, investigating how the current guidelines are applied is crucial. The first aim of this study was to assess dentists' implementation of the current guidelines. The secondary aims were to identify relevant areas to improve the training of dentists and to determine temporal trends in practitioners' attitudes by comparison with 2 previous surveys conducted in 1991 and 2001...
October 18, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29161405/quantifying-infective-endocarditis-risk-in-patients-with-predisposing-cardiac-conditions
#9
Martin H Thornhill, Simon Jones, Bernard Prendergast, Larry M Baddour, John B Chambers, Peter B Lockhart, Mark J Dayer
Aims: There are scant comparative data quantifying the risk of infective endocarditis (IE) and associated mortality in individuals with predisposing cardiac conditions. Methods and results: English hospital admissions for conditions associated with increased IE risk were followed for 5 years to quantify subsequent IE admissions. The 5-year risk of IE or dying during an IE admission was calculated for each condition and compared with the entire English population as a control...
November 17, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29129257/temporal-changes-in-infective-endocarditis-guidelines-during-the-last-12-years-high-level-evidence-needed
#10
Lauge Østergaard, Nana Valeur, Henning Bundgaard, Jawad H Butt, Nikolaj Ihlemann, Lars Køber, Emil L Fosbøl
BACKGROUND: Infective endocarditis (IE) is a complex disease necessitating extensive clinical guidelines. The guidelines from the American Heart Association (AHA) and the European Society of Cardiology (ESC) have been markedly extended during the last 12 years. We examined the evidence base for these changes. METHODS: IE guidelines published by AHA and ESC were reviewed. We categorized and combined guidelines into 3 time periods: (1) 2004 (AHA) and 2005 (ESC), (2) 2007 (AHA) and 2009 (ESC), and (3) 2015 (AHA) and 2015 (ESC)...
November 2017: American Heart Journal
https://www.readbyqxmd.com/read/29121980/a-complicated-prosthetic-valve-endocarditis-due-to-methicillin-resistant-staphylococci-treated-with-linezolid-and-ciprofloxacin-a-case-report
#11
C G K Amiyangoda, H Wimalaratna, S Bowatte
BACKGROUND: Prosthetic valve endocarditis (PVE) due to methicillin resistant Staphylococcus aureus (MRSA) is a rare disease with significant mortality and morbidity. With the emerging resistance and adverse effect profile of vancomycin which is the standard treatment, there is a compelling necessity of an effective alternative for vancomycin. Linezolid is proved as such an agent for infections caused by MRSA in other sites. However to-date the evidence for successful use of linezolid for MRSA prosthetic valve endocarditis is limited only for few case studies...
November 9, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29107651/is-antibiotic-prophylaxis-to-prevent-infective-endocarditis-worthwhile
#12
REVIEW
Mark Dayer, Martin Thornhill
Infective endocarditis (IE) is a rare condition which is associated with considerable morbidity and mortality. Almost 100 years ago, the links between endocarditis and procedures, particularly dental procedures, were postulated. Over 50 years ago the first guidelines recommending antibiotic prophylaxis (AP), with the aim of preventing IE developing after procedures, were proposed. However, there has only ever been circumstantial evidence in humans that AP prevents IE. The rarity of IE has made a randomised controlled clinical trial impractical to date...
October 26, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29077791/prosthetic-valve-candida-spp-endocarditis-new-insights-into-long-term-prognosis-the-escape-study
#13
Claire Rivoisy, Antonio Vena, Laura Schaeffer, Caroline Charlier, Arnaud Fontanet, François Delahaye, Emilio Bouza, Olivier Lortholary, Patricia Munoz, Agnès Lefort
Background: Prosthetic valve endocarditis caused by Candida spp. (PVE-C) is rare and devastating, with international guidelines based on expert recommendations consisting in the combination of surgery and subsequent azole treatment. Methods: PVE-C collected in Spain and France between 2001 and 2015 were retrospectively analyzed with a focus on management and outcome. Results: Forty-six cases were followed up for a median of 9 months. Twenty-two (48%) patients had a past history of endocarditis; 30 (65%) cases were nosocomial or healthcare-related, 9 (20%) patients were intravenous drug users...
October 25, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29071426/echocardiography-in-infective-endocarditis-state-of-the-art
#14
REVIEW
Luis Afonso, Anupama Kottam, Vivek Reddy, Anirudh Penumetcha
PURPOSE OF REVIEW: In this review, we examine the central role of echocardiography in the diagnosis, prognosis, and management of infective endocarditis (IE). RECENT FINDINGS: 2D transthoracic echocardiography (TTE) and transesophageal echocardiography TEE have complementary roles and are unequivocally the mainstay of diagnostic imaging in IE. The advent of 3D and multiplanar imaging have greatly enhanced the ability of the imager to evaluate cardiac structure and function...
October 25, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/29064220/the-management-of-infections-and-the-use-of-antibiotic-prophylaxis-by-dentists-a-review-of-the-evidence
#15
George Maranon
Dentistry plays an important role in managing the antibiotic resistance problem. Guidelines for the use of antibiotics for prevention of endocarditis, prosthetic joint infections and other medical conditions have changed frequently. Unfortunately, the original guidelines and subsequent changes were often made through consensus opinions and not evidence based. Clinical decisions on the use of antibiotics must be made on the basis of the scientific evidence with knowledge of the most current guidelines and indications...
March 2017: Journal of the California Dental Association
https://www.readbyqxmd.com/read/29055511/the-relationship-between-causative-microorganisms-and-cardiac-lesions-caused-by-infective-endocarditis-new-perspectives-from-the-contemporary-cohort-of-patients
#16
Danijela Trifunovic, Bosiljka Vujisic-Tesic, Biljana Obrenovic-Kircanski, Branislava Ivanovic, Dimitra Kalimanovska-Ostric, Milan Petrovic, Marija Boricic-Kostic, Snezana Matic, Goran Stevanovic, Jelena Marinkovic, Olga Petrovic, Gordana Draganic, Mirjana Tomic-Dragovic, Svetozar Putnik, Dejan Markovic, Vladimir Tutus, Ivana Jovanovic, Maja Markovic, Ivana M Petrovic, Jelena M Petrovic, Jelena Stepanovic
BACKGROUND: The etiology of infective endocarditis (IE) is changing. More aggressive forms with multiple IE cardiac lesions have become more frequent. This study sought to explore the relationship between contemporary causative microorganisms and IE cardiac lesions and to analyze the impact of multiple lesions on treatment choice. METHODS: In 246 patients hospitalized for IE between 2008 and 2015, cardiac lesions caused by IE were analyzed by echocardiography, classified according to the 2015 European Society of Cardiology guidelines and correlated with microbiological data...
October 18, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29034174/rare-case-of-rhizobium-radiobacter-bioprosthetic-mitral-valve-endocarditis
#17
Ryan Halas, Chris Jacob, Karun Badwal, Rafi Mir
Rhizobium radiobacter is an aerobic, gram negative, rod-shaped, bacterium typically found in the soil. Commonly a plant pathogen, it is also a rare human pathogen causing serious disease. Risk factors for infection include neutropenia, leukopenia, catheters, hospitalization, and low CD4+ lymphocyte count, especially in patients with malignancy or human immunodeficiency virus. There is currently limited literature to establish a definitive guideline for antimicrobial therapy and obtaining susceptibilities from a specialized laboratory is appropriate...
2017: IDCases
https://www.readbyqxmd.com/read/29026622/lower-extremity-mycotic-aneurysm-in-a-patient-with-listeria-monocytogenes-associated-prosthetic-valve-endocarditis
#18
Elham Rahmati, P Jan Geiseler, Rosemary C She
Introduction.Listeria monocytogenes is a rare etiology of infectious endocarditis with only 30 cases of prosthetic valve and about twice as many native valve infections described in the literature. We describe an unusual presentation of an endovascular embolic phenomenon with associated lower extremity mycotic aneurysm due to Listeria monocytogenes prosthetic aortic valve and aortic endograft infection. Case presentation. This is a case of an elderly gentleman with prior history of bioprosthetic aortic valve placement and aortic arch repair who was admitted with several weeks of constitutional symptoms and left lower leg pain...
May 2017: JMM Case Reports
https://www.readbyqxmd.com/read/28991871/treatment-of-st-elevation-myocardial-infarction-in-the-setting-of-infective-endocarditis-a-need-for-treatment-guidelines
#19
Nnaemeka Ukwuoma, Daniel Villarreal, Ravi Doobay, Jennifer Proctor
No abstract text is available yet for this article.
October 2, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28988732/rupture-of-an-occult-intracranial-mycotic-aneurysm-after-intravenous-thrombolysis-with-recombinant-tissue-plasminogen-activator-for-acute-ischemic-stroke
#20
Jared Glenn, Margaret Strecker-McGraw, Ian McGraw, Karim Jabbar, Nathan A James, C Keith Stone
BACKGROUND: The treatment of acute ischemic stroke with recombinant tissue plasminogen activator (rtPA) has become the mainstay of treatment, but its use carries a risk of subsequent intracranial hemorrhage (ICH). Guidelines have been developed to aid in the selection of the appropriate candidates to treat with rtPA to reduce this risk. We present a case of a stroke patient who was an appropriate candidate and was treated with rtPA who experienced a fatal subarachnoid hemorrhage due to a ruptured mycotic aneurysm (MA)...
November 2017: Journal of Emergency Medicine
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