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https://www.readbyqxmd.com/read/28222575/the-effect-of-pacing-strategy-on-physiological-kinetic-and-performance-variables-during-simulated-rowing-ergometer
#1
Eleni Dimakopoulou, Elias Zacharogiannis, Chrysoula Chairopoulou, Socratis Kaloupsis, Theodoros Platanou
BACKGROUND: This study compared the effects of self selected (SSP), negative (NPS) and even (EPS) pacing strategy on performance time, kinetic and physiological variables in overall 2km rowing and in first and second 1km. METHODS: Fifteen male rowers (15.37 ± 1.34 yrs) realized four tests: an incremental test on a rowing ergometer to determine their VO2peak and three experimental 2 km rowing race, where first 1km was manipulated. From SSP a negative pacing strategy, 4% slower than the mean velocity of SSP, and an even pacing strategy (EPS) with mean velocity of SSP, were developed...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28222558/effects-of-gait-training-using-the-hybrid-assistive-limb%C3%A2-%C3%A2-in-recovery-phase-stroke-patients-a-2-month-follow-up-randomized-controlled-study
#2
Hiroki Watanabe, Ryohei Goto, Naoki Tanaka, Akira Matsumura, Hisako Yanagi
BACKGROUND: Gait training using the Hybrid Assistive Limb ® (HAL ®) may have beneficial effects on post-stroke gait function and independent walking. However, the long-term and medium-term efficacies of gait training using HAL ® in stroke patients remain unclear. OBJECTIVE: To compare the medium-term efficacy of gait training using a single-leg version of the Hybrid Assistive Limb ® (HAL ®) on the paretic side with conventional gait training (CGT) in recovery-phase stroke patients...
January 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222534/a-meta-analysis-of-memantine-for%C3%A2-depression
#3
Taro Kishi, Shinji Matsunaga, Nakao Iwata
We conducted a systematic review and meta-analysis on whether memantine was beneficial for the treatment of depressive symptoms in major depressive disorder (MDD) and bipolar disorder (BD). The analysis included double-blind, randomized, placebo-controlled trials of memantine in MDD and BD. The primary outcome measures for efficacy and safety were response rate and all-cause discontinuation, respectively. Risk ratio (RR) and standardized mean difference with 95% confidence intervals (95% CI) were calculated...
February 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222514/one-year-evolution-of-behavioral-and%C3%A2-psychological-symptoms-of-dementia-in-patients-initially-hospitalized-in%C3%A2-cognitive-behavioral-units-the-evital-prospective-cohort
#4
Isabelle Rouch, Elodie Pongan, Béatrice Trombert, Florence Fabre, Nicolas Auguste, Claire Sellier, Magalie Freulon, Sophie Jacqueline, Denis Federico, Christelle Mouchoux, Géraldine Martin-Gaujard, Pierre Krolak-Salmon, Bernard Laurent, Jean-Michel Dorey
BACKGROUND: The 2008-2012 French Alzheimer's Plan has provided hospital Cognitive and Behavioral Units (CBU) to improve the management of patients with productive behavioral and psychological symptoms of dementia (BPSD). Little is known concerning the behavioral outcome of these patients after discharge. OBJECTIVE: The present study investigated the long-term evolution of BPSD over one year after CBU discharge. METHODS: The EVITAL cohort included 221 participants admitted to the CBUs of 3 French hospitals...
February 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222489/characterization-of-a-novel-signal-transducer-element-intrinsic-to-class-iiia-b-adenylate-cyclases-and-guanylate-cyclases
#5
Miriam Ziegler, Jens Bassler, Stephanie Beltz, Anita Schultz, Andrei N Lupas, Joachim E Schultz
Adenylate cyclases (ACs) are signalling proteins that produce the second messenger cAMP. Class III ACs comprises four groups (class IIIa-d); of these, class IIIa and IIIb ACs have been identified in bacteria and eukaryotes. Many class IIIa ACs are anchored to membranes via hexahelical domains. In eukaryotic ACs, membrane anchors are well conserved, suggesting that this region possesses important functional characteristics that are as yet unknown. To address this question, we replaced the hexahelical membrane anchor of the mycobacterial AC Rv1625c by the hexahelical quorum-sensing receptor from Legionella, LqsS...
February 21, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28222487/pyrrole-derivatives-and-diterpene-alkaloids-from-the-south-china-sea-sponge-agelas-nakamurai
#6
Mei-Jun Chu, Xu-Li Tang, Guo-Fei Qin, Yan-Ting Sun, Lei Li, Nicole J de Voogd, Ping-Lin Li, Guo-Qiang Li
Two pairs of new non-brominated racematic pyrrole derivatives, (±)-nakamurine D (1) and (±)-nakamurine E (2), two new diterpene alkaloids, iso-agelasine C (16), and iso-agelasidine B (21), together with fifteen known pyrrole derivatives((±)-3 - 15), five known diterpene alkaloids (17 - 20, 22) were isolated from the South China Sea sponge Agelas nakamurai. The racemic mixtures, compounds 1 - 4, were resolved into four pairs of enantiomers, (+)-1 and (-)-1, (+)-2 and (-)-2, (+)-3 and (-)-3, and (+)-4 and (-)-4, by chiral HPLC...
February 21, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28222465/autologous-conditioned-plasma-versus-placebo-injection-therapy-in-lateral-epicondylitis-of-the-elbow-a-double-blind-randomized-study
#7
Volker Schöffl, Wolfgang Willauschus, Felix Sauer, Thomas Küpper, Isabelle Schöffl, Christoph Lutter, Kolja Gelse, Jörg Dickschas
Introduction There are various therapeutic approaches to the treatment of lateral epicondylitis, a highly prevalent musculoskeletal disorder. Recently, injection therapy with autologous conditioned plasma (ACP) has shown promise as a new approach. Methods Set up as a prospective, double-blind, randomized controlled clinical trial, this study involved 50 patients with lateral epicondylitis. Following external randomization, 25 patients received one round of injection therapy with ACP (platelet rich plasma, PRP), while the remaining 25 patients received a placebo of 0...
February 21, 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/28222235/visual-appearance-of-a-virtual-upper-limb-modulates-the-temperature-of-the-real-hand-a-thermal-imaging-study-in-immersive-virtual-reality
#8
G Tieri, A Gioia, M Scandola, E F Pavone, S M Aglioti
To explore the link between Sense of Embodiment (SoE) over a virtual hand and physiological regulation of skin temperature, twenty-four healthy participants were immersed in virtual reality through a Head Mounted Display and had their real limb temperature recorded by means of a high-sensitivity infrared camera. Participants observed a virtual right upper limb (appearing either normally, or with the hand detached from the forearm) or limb-shaped non-corporeal control objects (continuous or discontinuous wooden blocks) from a first-person perspective...
February 21, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28222199/examining-current-or-future-trade-offs-for-biodiversity-conservation-in-north-eastern-australia
#9
April E Reside, Jeremy VanDerWal, Atte Moilanen, Erin M Graham
With the high rate of ecosystem change already occurring and predicted to occur in the coming decades, long-term conservation has to account not only for current biodiversity but also for the biodiversity patterns anticipated for the future. The trade-offs between prioritising future biodiversity at the expense of current priorities must be understood to guide current conservation planning, but have been largely unexplored. To fill this gap, we compared the performance of four conservation planning solutions involving 662 vertebrate species in the Wet Tropics Natural Resource Management Cluster Region in north-eastern Australia...
2017: PloS One
https://www.readbyqxmd.com/read/28222182/epidemiological-tracing-of-bovine-tuberculosis-in-switzerland-multilocus-variable-number-of-tandem-repeat-analysis-of-mycobacterium-bovis-and-mycobacterium-caprae
#10
Giovanni Ghielmetti, Simone Scherrer, Ute Friedel, Daniel Frei, Dominique Suter, Lukas Perler, Max M Wittenbrink
BACKGROUND: After 15 years of absence, in 2013 bovine tuberculosis (bTB), caused by Mycobacterium (M.) bovis and M. caprae, reemerged in the Swiss dairy cattle population. In order to identify the sources of infection as well as the spread of the agents, molecular-epidemiologic tracing by MIRU-VNTR analysis in combination with spoligotyping was performed. A total of 17 M. bovis and 7 M. caprae isolates were cultured from tuberculous bovine lymph nodes and analyzed with a set of 49 genetic markers by using automated capillary electrophoresis...
2017: PloS One
https://www.readbyqxmd.com/read/28222156/toothbrush-abrasivity-in-a-long-term-simulation-on-human-dentin-depends-on-brushing-mode-and-bristle-arrangement
#11
Mozhgan Bizhang, Ilka Schmidt, Yong-Hee Patricia Chun, Wolfgang H Arnold, Stefan Zimmer
OBJECTIVE: The aim of this study was to evaluate the susceptibility of dentin to brushing abrasion using four different toothbrushes (rotating-oscillating, sonic and two types of manual toothbrushes) with the same brushing forces. METHODS: Dentin samples (n = 72) were selected from 72 impacted third molars. Half of the surface of dentin samples was covered with an adhesive tape, creating a protected and a freely exposed area in the same specimen. Brushing was performed with either a: sonic (Sonicare PowerUp, Philips GmbH, Hamburg, Germany), b: oscillating-rotating (Oral B Vitality Precisions Clean, Procter & Gamble, Schwalbach am Taunus, Germany) or two different manual toothbrushes c: flat trim brush head toothbrush (Dr...
2017: PloS One
https://www.readbyqxmd.com/read/28222130/dengue-virus-antibody-database-systematically-linking-serotype-specificity-with-epitope-mapping-in-dengue-virus
#12
Sidhartha Chaudhury, Gregory D Gromowski, Daniel R Ripoll, Ilja V Khavrutskii, Valmik Desai, Anders Wallqvist
BACKGROUND: A majority infections caused by dengue virus (DENV) are asymptomatic, but a higher incidence of severe illness, such as dengue hemorrhagic fever, is associated with secondary infections, suggesting that pre-existing immunity plays a central role in dengue pathogenesis. Primary infections are typically associated with a largely serotype-specific antibody response, while secondary infections show a shift to a broadly cross-reactive antibody response. METHODS/PRINCIPAL FINDINGS: We hypothesized that the basis for the shift in serotype-specificity between primary and secondary infections can be found in a change in the antibody fine-specificity...
February 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28222110/different-antibiotic-growth-promoters-induce-specific-changes-in-the-cecal-microbiota-membership-of-broiler-chicken
#13
Marcio C Costa, Jose A Bessegatto, Amauri A Alfieri, J Scott Weese, João A B Filho, Alexandre Oba
Antimicrobials are sometimes given to food animals at low doses in order to promote faster growth. However, the mechanisms by which those drugs improve performance are not fully understood. This study aimed to investigate the impact of zinc bacitracin (55g/ton), enramycin (10g/ton); halquinol® (30g/ton); virginiamycin (16,5g/ton) and avilamycin (10g/ton) on the cecal microbiota of broiler chicken, compared to a control group. Six hundred and twenty four chicks (Cobb 500) arriving to an experimental unit were randomly assigned into each treatment with four repetitions per treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28222019/practical-motives-are-prominent-in-test-ordering-in-the-emergency-department
#14
Armando van der Horst, Dennis J van de Wijngaart, Jolanda Scherrenburg, Nadine van Dijk, Pim M W Janssens
BACKGROUND: Laboratory test ordering under time pressure may impact test-ordering behavior. METHODS: To investigate the test-ordering behavior of doctors working under such pressure, we designed a questionnaire for trainees and staff in the Emergency Department (ED). This questionnaire addressed topics such as necessity of requested tests, time spent on ordering, costs and availability of tests, and the time of the day. We hypothesized that ordering behavior would be guided predominantly by the medical need of tests and aimed at identifying practical motives that also have an effect...
February 21, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28221989/evaluation-of-a-multiplex-pcr-assay-for-the-identification-of-salmonella-serovars-enteritidis-and-typhimurium-using-retail-and-abattoir-samples
#15
Dele Ogunremi, Susan Nadin-Davis, Andrée Ann Dupras, Imelda Gálvan Márquez, Katayoun Omidi, Louise Pope, John Devenish, Teresa Burke, Ray Allain, Daniel Leclair
A multiplex PCR was developed to identify the two most common serovars of Salmonella causing foodborne illness in Canada, namely, serovars Enteritidis and Typhimurium. The PCR was designed to amplify DNA fragments from four Salmonella genes, namely, invA gene (211-bp fragment), iroB gene (309-bp fragment), Typhimurium STM 4497 (523-bp fragment), and Enteritidis SE147228 (612-bp fragment). In addition, a 1,026-bp ribosomal DNA (rDNA) fragment universally present in bacterial species was included in the assay as an internal control fragment...
February 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221969/development-and-validation-of-pathogen-environmental-monitoring-programs-for-small-cheese-processing-facilities
#16
Sarah M Beno, Matthew J Stasiewicz, Alexis D Andrus, Robert D Ralyea, David J Kent, Nicole H Martin, Martin Wiedmann, Kathryn J Boor
Pathogen environmental monitoring programs (EMPs) are essential for food processing facilities of all sizes that produce ready-to-eat food products exposed to the processing environment. We developed, implemented, and evaluated EMPs targeting Listeria spp. and Salmonella in nine small cheese processing facilities, including seven farmstead facilities. Individual EMPs with monthly sample collection protocols were designed specifically for each facility. Salmonella was detected in only one facility, with likely introduction from the adjacent farm indicated by pulsed-field gel electrophoresis data...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221919/variation-in-campylobacter-multilocus-sequence-typing-subtypes-from-chickens-as-detected-on-three-plating-media
#17
M E Berrang, S R Ladely, R J Meinersmann, J E Line, B B Oakley, N A Cox
The objective of this study was to compare subtypes of Campylobacter jejuni and Campylobacter coli detected on three selective Campylobacter plating media to determine whether each medium selected for different subtypes. Fifty ceca and 50 carcasses (representing 50 flocks) were collected from the evisceration line in a commercial broiler processing plant. Campylobacter was cultured and isolated from cecal contents and carcass rinses on Campy-Cefex, Campy Line, and RF Campylobacter jejuni/coli agars. When a positive result was obtained with all three media, one colony of the most prevalent morphology on each medium was selected for further analysis by full genome sequencing and multilocus sequence typing...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221896/accuracy-and-thoroughness-of-treatment-summaries-provided-as-part-of-survivorship-care-plans-prepared-by-two-cancer-centers
#18
Amye J Tevaarwerk, William G Hocking, Jamie L Zeal, Mindy Gribble, Lori Seaborne, Kevin A Buhr, Kari B Wisinski, Mark E Burkard, Douglas A Wiegmann, Mary E Sesto
PURPOSE: Treatment summaries prepared as part of survivorship care planning should correctly and thoroughly report diagnosis and treatment information. METHODS: As part of a clinical trial, summaries were prepared for patients with stage 0 to III breast cancer at two cancer centers. Summaries were prepared per the standard of care at each center via two methods: using the electronic health record (EHR) to create and facilitate autopopulation of content or using manual data entry into an external software program to create the summary...
February 21, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28221873/characterization-of-enterohemorrhagic-escherichia-coli-on-veal-hides-and-carcasses
#19
Joseph M Bosilevac, Rong Wang, Brandon E Luedtke, Susanne Hinkley, Tommy L Wheeler, Mohammad Koohmaraie
Enterohemorrhagic Escherichia coli (EHEC) are Shiga toxin-producing E. coli associated with the most severe forms of foodborne illnesses. The U.S. Department of Agriculture, Food Safety and Inspection Service has identified a higher percentage of non-O157 EHEC compared with E. coli O157:H7-positive samples collected from veal trimmings than from products produced from other cattle slaughter classes. Therefore samples were collected from hides and preevisceration carcasses at five veal processors to assess E...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221858/genotypic-and-phenotypic-characterization-of-methicillin-resistant-staphylococcus-aureus-isolated-from-bovine-mastitic-milk-in-korea
#20
Jae Won Song, Soo Jin Yang, Sook Shin, Keun Seok Seo, Yong Ho Park, Kun Taek Park
Staphylococcus aureus is a major etiological pathogen for bovine mastitis, foodborne illness, and various clinical infections. Methicillin-resistant S. aureus (MRSA) has been isolated from bovine mastitic milk, and the presence of MRSA in milk is a major public health concern. We investigated the frequency of MRSA isolation from mastitic raw milk in Korea and characterized the patterns of antimicrobial resistance, virulence, and genotypes of the MRSA isolates. A total of 1,222 raw milk samples were collected from 47 dairy farms in Gyeonggi province from 2011 to 2012...
October 2016: Journal of Food Protection
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