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Hemangioma

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https://www.readbyqxmd.com/read/28551065/role-of-selective-intra-arterial-embolization-in-benign-liver-tumors
#1
M D Ferrer Puchol, C La Parra Casado, A Cervera Araez, R Sala López, E Esteban Hernández, A Cremades Mira, R Ramiro Gandia
OBJECTIVE: To present cases of symptomatic benign liver tumors diagnosed and treated with intra-arterial embolization before surgery. MATERIAL AND METHODS: We present the cases of 7 patients diagnosed with symptomatic benign liver tumors that required treatment: 1 focal nodular hyperplasia, 2 giant cavernous hemangiomas, 1 hepatic adenomatosis, and 3 hepatic adenomas. Once the feeding arteries were identified, tumors were embolized with polyvinyl alcohol particles (500μm-700μm) and then the feeding artery was plugged with coils if there was an arterial pedicle to ensure the total vascular exclusion of the tumor...
May 24, 2017: Radiología
https://www.readbyqxmd.com/read/28550689/a-diagnostic-program-of-vascular-tumor-and-vascular-malformations-in-children-according-to-modern-classification
#2
Iryna Benzar
The aim of the study was to analyze the cohort of inpatient children with vascular anomalies according to the globally accepted classification introduced by the ISSVA. METHODS: The study included 205 inpatient children within the time period of the years 2010-2015. Types of vascular anomalies (VAs), age of patients, diagnostic procedures, and anatomical localization of VAs were analyzed. RESULTS: 65 patients of first year of life had vascular tumors, with prevalence of infantile hemangiomas (IHs) in 57 (87...
May 26, 2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/28548465/assessment-of-infantile-hemangiomas-using-a-handheld-wireless-diffuse-optical-spectroscopic-device
#3
Christopher J Fong, Maria C Garzon, Jennifer W Hoi, Hyun K Kim, Christine T Lauren, Kimberly Morel, Lauren Geller, Nina Antonov, Nicole Weitz, June Wu, Andreas H Hielscher
BACKGROUND/OBJECTIVES: Infantile hemangiomas (IHs) are vascular tumors with the potential for significant morbidity. There is a lack of validated objective tools to assess IH severity and response to treatment. Diffuse optical spectroscopy (DOS), a noninvasive, nonionizing imaging modality, can measure total hemoglobin concentration and hemoglobin oxygen saturation in tissue to assess IH vascularity and response to treatment. Our objective was to evaluate the utility of a wireless, handheld DOS system to assess IH characteristics at selected points during their clinical course...
May 26, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28546918/b-cell-receptor-signaling-pathway-involved-in-benign-lymphoepithelial-lesions-of-the-lacrimal-gland
#4
Xiao-Na Wang, Xin Ge, Jing Li, Xiao Liu, Jian-Min Ma
AIM: To detect the expression of B cell receptor signaling pathway (BCRSP) in lacrimal gland benign lymphoepithelial lesions (LGBLEL). METHODS: Gene microarray was used to compare whole-genome expression in lacrimal gland tissues from LGBLEL patients to tissues from orbital cavernous hemangioma (control tissues). Expression of BCRSP was confirmed by polymerase chain reaction (PCR) and immunohistochemistry. RESULTS: The expression of 22 genes of the BCRSP increased significantly in LGBLEL patients...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28546705/sinonasal-mass-a-recent-study-of-its-clinicopathological-profile
#5
P Agarwal, R Panigrahi
A variety of non-neoplastic and neoplastic conditions involving the nasal cavity, paranasal sinuses (PNS), and nasopharynx are commonly encountered in clinical practice. The objectives of the study were to identify various pathological conditions that present with sinus or nasal mass, to understand their varied clinical behavior, to know the distribution of various lesions among the different age and sex groups, and to study the management of sinonasal masses and its outcome on follow-up. A prospective study was carried out from September 2013 to August 2015, in the Otorhinolaryngology Department of Hi-Tech Medical College & Hospital, Bhubaneswar, Odisha...
June 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28545938/an-update-of-77-cases-diagnosed-as-oral-hemangiomas-based-on-glut-1-positivity
#6
Tiago João da Silva Filho, Denise Hélen Imaculada Pereira de Oliveira, Veruska Lima Moura Brasil, Cassiano Francisco Weege Nonaka, Éricka Janine Dantas da Silveira, Lélia Maria Guedes Queiroz
OBJECTIVES: To evaluate cases diagnosed as "oral hemangiomas" based on the immunohistochemical expression of human glucose transporter protein (GLUT-1) and on histopathological features, and to investigate whether the classification proposed by the ISSVA was used correctly to classify these lesions. MATERIAL AND METHODS: All cases stored in the archives of an Oral Pathology Service and diagnosed as "oral hemangiomas" were reviewed. Seventy-seven cases were analyzed regarding the expression of GLUT-1...
May 22, 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/28544751/constitutional-abnormalities-of-idh1-combined-with-secondary-mutations-predispose-a-patient-with-maffucci-syndrome-to-acute-lymphoblastic-leukemia
#7
Shinsuke Hirabayashi, Masafumi Seki, Daisuke Hasegawa, Motohiro Kato, Nobuyuki Hyakuna, Takuya Shuo, Shunsuke Kimura, Kenichi Yoshida, Keisuke Kataoka, Yoichi Fujii, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Nobutaka Kiyokawa, Satoru Miyano, Seishi Ogawa, Junko Takita, Atsushi Manabe
Maffucci syndrome is a nonhereditary disorder caused by somatic mosaic isocitrate dehydrogenase 1 or 2 (IDH1 or IDH2) mutations and is characterized by multiple enchondromas along with hemangiomas. Malignant transformation of enchondromas to chondrosarcomas and secondary neoplasms, such as brain tumors or acute myeloid leukemia, are serious complications. A 15-year-old female with Maffucci syndrome developed B-cell precursor acute lymphoblastic leukemia (BCP-ALL). A somatic mutation in IDH1 was detected in hemangioma and leukemic cells...
May 24, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28543755/comparison-of-two-formulations-of-topical-timolol-for-the-treatment-of-infantile-hemangiomas
#8
Michelle Si Ying Ng, Yong-Kwang Tay, Shanna Shan-Yi Ng, Alice Yee Wah Foong, Mark Jean-Aan Koh
This report compares the efficacy of timolol maleate 0.5% eyedrops (TM) with that of timolol maleate 0.5% ophthalmic gel-forming solution in the treatment of infantile hemangiomas (IHs). Sixty-six patients undergoing treatment with topical timolol were retrospectively reviewed; our results revealed similar therapeutic efficacies for both types of timolol formulations. Early treatment initiation (<3 mos) and superficial lesions correlated with better treatment response. TM eyedrops may be a more cost effective, equally efficacious modality of treatment for IHs...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28540347/interdisciplinary-management-of-head-and-neck-vascular-anomalies-clinical-presentation-diagnostic-findings-and-minimalinvasive-therapies
#9
REVIEW
Maliha Sadick, Walter A Wohlgemuth, Roland Huelse, Bettina Lange, Thomas Henzler, Stefan O Schoenberg, Haneen Sadick
OBJECTIVES: Vascular anomalies are included in the 30 000 rare diseases worldwide affecting less than 5/10 000 people. Depending on their morphology and biological properties, they can cause varied disorders with organ involvement. Almost 60% of vascular anomalies have a predilection for the head and neck region in children. Clinical and scientific effort to establish interdisciplinary management concepts for vascular anomalies is increasing worldwide. METHODS: Especially in the head and neck region, clinical impairment and organ dysfunction is associated with cosmetic issues that may represent a physical and psychological issue for the patient...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28540013/infantile-periocular-hemangioma
#10
REVIEW
Mehdi Tavakoli, Saeid Yadegari, Mahnaz Mosallaei, Maryam Aletaha, Hossein Salour, Wendy W Lee
Infantile periocular hemangiomas (IPH) are common benign vascular tumors that present early in childhood. They typically show a rapid nonlinear growth pattern a few weeks after birth during a proliferative phase, then continue with an involution phase and may result in serious ocular or systemic complications. Theses tumors may present in a range of small isolated lesions to multiple, diffuse involvements. Understanding the nature of the disease, the natural course, complications, indications for intervention, and treatment modalities would be helpful for ophthalmologists, who will likely be consulted for periocular cases...
April 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28538565/urinary-excretion-of-microrna-126-is-a-biomarker-for-hemangioma-proliferation
#11
Ayan Biswas, Xueliang Pan, Melissa Meyer, Savita Khanna, Sashwati Roy, Gregory Pearson, Richard Kirschner, Patricia Witman, Esteban Fernandez Faith, Chandan K Sen, Gayle M Gordillo
BACKGROUND: Hemangiomas are unique endothelial cell tumors that involute spontaneously, which makes interpreting their response to therapies difficult. The objective of this work was to identify a potential biomarker in the urine of children with infantile hemangiomas that would facilitate testing new therapies. METHODS: A prospective longitudinal study in children with hemangiomas and age-matched healthy controls was performed to determine whether microRNA-126, which is highly abundant in fetal endothelial cells, was more abundant in the urine of affected children...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28538262/parafoveal-microvascular-features-on-optical-coherence-tomography-angiography-in-eyes-with-circumscribed-choroidal-hemangioma
#12
Kareem Sioufi, Emil A T Say, Sandor C Ferenczy, Carol L Shields
PURPOSE: To evaluate parafoveal microvasculature in eyes with circumscribed choroidal hemangioma using optical coherence tomography angiography. METHODS: Fourteen eyes with unilateral circumscribed choroidal hemangioma were imaged using OCT for central macular thickness and optical coherence tomography angiography for superficial and deep foveal avascular zone area, and superficial and deep capillary density (CD), comparing affected and paired fellow eyes. RESULTS: Mean patient age was 53 years, and mean visual acuity was 20/60 in the involved eye and 20/25 in the fellow eye...
May 19, 2017: Retina
https://www.readbyqxmd.com/read/28537410/-liver-hemangiomas-when-is-invasive-treatment-indicated
#13
V Třeška, T Skalický, V Liška, J Fichtl, J Brůha, M Skála, J Šebek, P Duras
INTRODUCTION: Liver hemangiomas are the most common benign tumors of the liver. Most are asymptomatic and are found accidentally by ultrasonography, computed tomography or magnetic resonance imaging of the abdomen. Liver hemangiomas usually do not need any treatment. Nevertheless, symptomatic, giant hemangiomas can be indicated for surgery, embolization or thermoablation. The aim of this study was to define based on our own experience and on the literature when and what treatment option should be indicated in patients suffering from liver hemangioma...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28537049/laser-treatment-for-urethral-hemangiomas-report-of-three-cases
#14
Mohammad Javad Soleimani, Pejman Shadpour, Kaveh Mehravaran, Amir Hossein Kashi
To present our experience with coagulation/laser treatment of urethral hemangiomas. Three cases with small to medium sized urethral hemangiomas in penile and posterior urethra presented with hematuria or urethral bloody discharge. All patients were male. They were treated with thermal or Nd-YAG laser coagulation in the first session. Recurrence of hematuria/bloody discharge happened in two patients within one month from the first treatment that was managed with a second session of laser coagulation. No third session of intervention for hematuria/bloody discharge was required in any patient during 10-39 months of follow up...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28536486/emerging-indications-for-fractionated-gamma-knife-radiosurgery
#15
Emory McTyre, Corbin A Helis, Michael Farris, Lisa Wilkins, Darrell Sloan, William H Hinson, J Daniel Bourland, William A Dezarn, Michael T Munley, Kounosuke Watabe, Fei Xing, Adrian W Laxton, Stephen B Tatter, Michael D Chan
BACKGROUND: Gamma Knife radiosurgery (GKRS) allows for the treatment of intracranial tumors with a high degree of dose conformality and precision. There are, however, certain situations wherein the dose conformality of GKRS is desired, but single session treatment is contraindicated. In these situations, a traditional pin-based GKRS head frame cannot be used, as it precludes fractionated treatment. OBJECTIVE: To report our experience in treating patients with fractionated GKRS using a relocatable, noninvasive immobilization system...
February 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28536212/incidental-discovery-of-a-large-complicated-arteriovenous-haemangioma
#16
Alberto Anthony Goizueta, Peter Libbey, Anthony Moulton, Rabih El-Bizri
Arteriovenous haemangiomas within the chest are rare and uncommonly documented. After a 60-year-old woman with a history of smoking underwent a routine chest X-ray revealing a right apical mass, further investigations led to the discovery of a large extrapulmonary arteriovenous haemangioma in the superior mediastinum. Additionally, this case became complicated when the hemangioma was found to not only be compressing adjacent major arteries and veins, but also invading into the spinal canal and displacing the spinal cord...
May 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28535651/-study-of-susceptibility-weighted-imaging-on-mr-and-pathologic-findings-to-distinguish-benign-or-malignant-soft-tissue-tumor
#17
J Liu, Y Chen, X M Bao, X L Ling, J P Ding, Z K Zhang
Objective: To explore the diagnostic performance of susceptibility weighted imaging (SWI)in distinguishing benign or malignant soft tissue tumor, and to study pathological observation. Methods: Sixty-eight patients with soft tissue tumor, who received no previous treatment or invasive examination, received routine preoperative MRI examination and SWI scanning. The graduation and distribution of intratumoral susceptibility signal intensity(ITSS) and proportion of tumor volume were observed.The pathological results were also included for comparative analysis...
May 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28533854/-a-rare-cause-of-exophthalmia-intraorbital-cavernous-hemangioma-about-a-case
#18
Abderrazzak El Saqui, Mohamed Aggouri, Mohamed Benzagmout, Khalid Chakour, Mohamed El Faiz Chaoui
Cavernous hemangioma is the most frequent primary benign vascular tumor of the orbit in the adult; the median age of diagnosis is 42 years with a female predominance. This tumor develops slowly and has no tendency for spontaneous regression; it is electively located at the level of the retro-ocular muscular cone but it can develop in the extraconic space. Clinically it appears as progressive irreducible, non-pulsating, painless (unless there's an unexpected complication) exophthalmia, associated with decrease in visual acuity in 2/3 of cases...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28529555/detection-of-p53-and-bcl-2-expression-in-cutaneous-hemangioma-through-the-quantum-dot-technique
#19
Tian Tang, Duan-Lian Zhang
Hemangioma is one of the most common types of infantile vascular benign tumor. The aim of the present study was to investigate the role of B-cell lymphoma 2 (Bcl-2) and tumor protein p53 (p53) in the proliferation and apoptosis of hemangioma cells. A total of 38 paraffin-embedded hemangioma specimens (16 males and 22 females) and another 5 paraffin-embedded healthy surrounding tissue samples, collected between January 2007 and December 2010, were obtained from the Department of Pathology at Renmin Hospital of Wuhan University (Wuhan, China)...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28523875/mimickers-of-infantile-hemangiomas
#20
Ross M Brockman, Stephen R Humphrey, David C Moe, Paula E North, David M King, John N Jensen, Dawn H Siegel, Beth A Drolet
Infantile hemangiomas (IHs) are the most common tumors of infancy and usually follow a typical course of growth and involution. We report four soft tissue tumors that were referred to the pediatric dermatology clinic as IHs and the process by which they were diagnosed and treated. Clinicians should be aware of presentations of these uncommon, but serious soft tissue tumors. Many of these mimickers have a vastly different clinical prognosis, and early intervention to limit sequelae is crucial. Biopsy of atypical lesions should be considered early in the diagnostic process since they have varied prognosis and treatment strategies...
May 2017: Pediatric Dermatology
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