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https://www.readbyqxmd.com/read/28927009/brush-polymer-of-donor-accepter-dyads-via-adduct-formation-between-lewis-base-polymer-donor-and-all-carbon-lewis-acid-acceptor
#1
Yang Wang, Miao Hong, Travis S Bailey, Eugene Y-X Chen
A synthetic method that taps into the facile Lewis base (LB)→Lewis acid (LA) adduct forming reaction between the semiconducting polymeric LB and all carbon LA C60 for the construction of covalently linked donor-acceptor dyads and brush polymer of dyads is reported. The polymeric LB is built on poly(3-hexylthiophene) (P3HT) macromers containing either an alkyl or vinyl imidazolium end group that can be readily converted into the N-heterocyclic carbene (NHC) LB site, while the brush polymer architecture is conveniently constructed via radical polymerization of the macromer P3HT with the vinyl imidazolium chain end...
September 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28926614/effect-of-chronic-stress-on-running-wheel-activity-in-mice
#2
Evan DeVallance, Dale Riggs, Barbara Jackson, Travis Parkulo, Stanley Zaslau, Paul D Chantler, I Mark Olfert, Randy W Bryner
Acute and chronic stress have been reported to have differing effects on physical activity in rodents, but no study has examined a chronic stress protocol that incorporates stressors often experienced by rodents throughout a day. To examine this, the effects of the Unpredictable Chronic Mild Stress (UCMS) protocol on voluntary running wheel activity at multiple time points, and/or in response to acute removal of chronic stress was determined. Twenty male Balb/c mice were given access and accustomed to running wheels for 4 weeks, after which they were randomized into 2 groups; exercise (EX, n = 10) and exercise with chronic stress using a modified UCMS protocol for 7 hours/day (8:00 a...
2017: PloS One
https://www.readbyqxmd.com/read/28926300/an-updated-scheme-for-categorizing-foods-implicated-in-foodborne-disease-outbreaks-a-tri-agency-collaboration
#3
LaTonia C Richardson, Michael C Bazaco, Cary Chen Parker, Daniel Dewey-Mattia, Neal Golden, Karen Jones, Karl Klontz, Curtis Travis, Joanna Zablotsky Kufel, Dana Cole
BACKGROUND: Foodborne disease data collected during outbreak investigations are used to estimate the percentage of foodborne illnesses attributable to specific food categories. Current food categories do not reflect whether or how the food has been processed and exclude many multiple-ingredient foods. MATERIALS AND METHODS: Representatives from three federal agencies worked collaboratively in the Interagency Food Safety Analytics Collaboration (IFSAC) to develop a hierarchical scheme for categorizing foods implicated in outbreaks, which accounts for the type of processing and provides more specific food categories for regulatory purposes...
September 19, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28925622/evaluating-physician-employment-contracts-how-do-your-benefits-measure-up
#4
Travis Singleton, Phil Miller
No abstract text is available yet for this article.
September 2017: Family Practice Management
https://www.readbyqxmd.com/read/28924493/evaluating-emotional-and-biological-sensitivity-to-maternal-behavior-among-self-injuring-and-depressed-adolescent-girls-using-nonlinear-dynamics
#5
Sheila E Crowell, Jonathan E Butner, Travis J Wiltshire, Ascher K Munion, Mona Yaptangco, Theodore P Beauchaine
High sensitivity and reactivity to behaviors of family members characterizes several forms of psychopathology, including self-inflicted injury (SII). We examined mother-daughter behavioral and psychophysiological reactivity during a conflict discussion using nonlinear dynamics to assess asymmetrical associations within time-series data. Depressed, SII, and control adolescents and their mothers participated (n=76 dyads). We expected that (1) mothers' evocative behaviors would affect behavioral and psychophysiological reactivity among depressed and, especially, SII adolescents, (2) adolescents' behaviors would not evoke mothers' behavioral or physiological reactivity, and (3) control teens and mothers would be less reactive, with no dynamic associations in either direction...
March 1, 2017: Clinical Psychological Science
https://www.readbyqxmd.com/read/28923914/new-ultrasound-techniques-promise-further-advances-in-aki-and-ckd
#6
REVIEW
Travis D Hull, Anupam Agarwal, Kenneth Hoyt
AKI and CKD are important clinical problems because they affect many patients and the associated diagnostic and treatment paradigms are imperfect. Ultrasound is a cost-effective, noninvasive, and simple imaging modality that offers a multitude of means to improve the diagnosis, monitoring, and treatment of both AKI and CKD, especially considering recent advances in this technique. Ultrasound alone can attenuate AKI and prevent CKD by stimulating the splenic cholinergic anti-inflammatory pathway. Additionally, microbubble contrast agents are improving the sensitivity and specificity of ultrasound for diagnosing kidney disease, especially when these agents are conjugated to ligand-specific mAbs or peptides, which make the dynamic assessment of disease progression and response to treatment possible...
September 18, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28922595/a-new-order-parameter-based-method-for-characterizing-radiation-damage-in-amorphous-materials
#7
Nikolaos Galanakis, Karl Patrick Travis
We present a new method of characterizing damage arising from α-recoil cascades in amorphous materials including glasses. The approach taken is topological, yielding information of atom connectivity and utilizing complete sets of orthogonal functions (spherical harmonics and Hermite functions) to compute order parameters. The utility of our new approach is demonstrated by first applying it to models of radiation damaged crystalline zircon, enabling validation against the standard defect counting method (Wigner-Seitz)...
September 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28921520/anti-m%C3%A3-llerian-hormone-and-risk-of-ovarian-cancer-in-nine-cohorts
#8
Seungyoun Jung, Naomi Allen, Alan A Arslan, Laura Baglietto, Aurelio Barricarte, Louise A Brinton, Brian L Egleston, Roni T Falk, Renée T Fortner, Kathy J Helzlsouer, Yutang Gao, Annika Idahl, Rudolph Kaaks, Vittorio Krogh, Melissa A Merritt, Eva Lundin, N Charlotte Onland-Moret, Sabina Rinaldi, Helena Schock, Xiao-Ou Shu, Patrick M Sluss, Paul N Staats, Carlotta Sacerdote, Ruth C Travis, Anne Tjønneland, Antonia Trichopoulou, Shelley S Tworoger, Kala Visvanathan, Elisabete Weiderpass, Anne Zeleniuch-Jacquotte, Joanne F Dorgan
Animal and experimental data suggest that anti-Müllerian hormone (AMH) serves as a marker of ovarian reserve and inhibits the growth of ovarian tumors. However, few epidemiologic studies have examined the association between AMH and ovarian cancer risk. We conducted a nested case-control study of 302 ovarian cancer cases and 336 matched controls from nine cohorts. Prediagnostic blood samples of premenopausal women were assayed for AMH using a picoAMH enzyme-linked immunosorbent assay. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable-adjusted conditional logistic regression...
September 18, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28921241/evaluating-the-efficacy-of-vaginal-dehydroepiandosterone-for-vaginal-symptoms-in-postmenopausal-cancer-survivors-ncctg-n10c1-alliance
#9
Debra L Barton, Jeff A Sloan, Lynne T Shuster, Paula Gill, Patricia Griffin, Kathleen Flynn, Shelby A Terstriep, Fauzia N Rana, Travis Dockter, Pamela J Atherton, Michaela Tsai, Keren Sturtz, Jacqueline M Lafky, Mike Riepl, Jacqueline Thielen, Charles L Loprinzi
BACKGROUND: Women with estrogen deficiencies can suffer from vaginal symptoms that negatively impact sexual health. This study evaluated vaginal dehydroepiandrosterone (DHEA) for alleviation of vaginal symptoms. METHODS: This three-arm randomized, controlled trial evaluated DHEA 3.25 mg and DHEA 6.5 mg, each compared to a plain moisturizer (PM) over 12 weeks, to improve the severity of vaginal dryness or dyspareunia, measured with an ordinal scale, and overall sexual health using the Female Sexual Function Index (FSFI)...
September 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28919862/changes-in-dimensionality-and-fractal-scaling-suggest-soft-assembled-dynamics-in-human-eeg
#10
Travis J Wiltshire, Matthew J Euler, Ty L McKinney, Jonathan E Butner
Humans are high-dimensional, complex systems consisting of many components that must coordinate in order to perform even the simplest of activities. Many behavioral studies, especially in the movement sciences, have advanced the notion of soft-assembly to describe how systems with many components coordinate to perform specific functions while also exhibiting the potential to re-structure and then perform other functions as task demands change. Consistent with this notion, within cognitive neuroscience it is increasingly accepted that the brain flexibly coordinates the networks needed to cope with changing task demands...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28919230/morbidity-and-mortality-of-meningioma-resection-increases-in-octogenarians
#11
Jeremy Steinberger, Rachel S Bronheim, Prashant Vempati, Eric K Oermann, Travis R Ladner, Nathan J Lee, Parth Kothari, John M Caridi, Raj K Shrivastava
BACKGROUND: The incidence of meningioma has increased drastically recently, particularly in the elderly. Surgical intervention has the potential to reduce neurological symptoms and to achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes following meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications following craniotomy for resection of meningioma...
September 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28919049/perioperative-outcomes-of-syndromic-paraganglioma-and-pheochromocytoma-resection-in-patients-with-von-hippel-lindau-disease-multiple-endocrine-neoplasia-type-2-or-neurofibromatosis-type-1
#12
James J Butz, Qi Yan, Travis J McKenzie, Toby N Weingarten, Alexandre N Cavalcante, Irina Bancos, William F Young, Darrell R Schroeder, David P Martin, Juraj Sprung
BACKGROUND: Pheochromocytoma and/or paraganglioma associated with neurofibromatosis type 1, multiple endocrine neoplasia type 2A, and von Hippel-Lindau disease have different catecholamine biochemical phenotypes. We examined perioperative outcomes of pheochromocytoma/paraganglioma resection in 3 syndromic forms. METHODS: Retrospective review of patients undergoing resection of syndromic pheochromocytoma/paraganglioma from 2000 through 2016. RESULTS: Eighty-one patients underwent pheochromocytoma/paraganglioma resection (multiple endocrine neoplasia type 2A, n = 36; neurofibromatosis type 1, n = 26; von Hippel-Lindau disease, n = 19)...
September 14, 2017: Surgery
https://www.readbyqxmd.com/read/28917558/cardiac-sympathectomy-for-the-management-of-ventricular-arrhythmias-refractory-to-catheter-ablation
#13
Travis Richardson, Ricardo Lugo, Pablo Saavedra, George Crossley, Walter Clair, Sharon Shen, Juan Carlos Estrada, Jay Montgomery, M Benjamin Shoemaker, Christopher Ellis, Gregory F Michaud, Eric Lambright, Arvindh Kanagasundram
BACKGROUND: Catheter ablation is now a mainstay of therapy for ventricular arrhythmias (VA). However, there are scenarios where either physiologic or anatomical factors make ablation less likely to be successful. OBJECTIVES: To demonstrate that cardiac sympathetic denervation (CSD) may be an alternate therapy for patients with difficult to ablate VA. METHODS: We identified all patients referred for CSD at a single center for indications other than LQTS and CPVT who had failed catheter ablation...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28914476/corrigendum-digital-quantification-of-dna-replication-and-chromosome-segregation-enables-determination-of-antimicrobial-susceptibility-after-only-15%C3%A2-minutes-of-antibiotic-exposure
#14
Nathan G Schoepp, Eugenia M Khorosheva, Travis S Schlappi, Matthew S Curtis, Romney M Humphries, Janet A Hindler, Rustem F Ismagilov
No abstract text is available yet for this article.
September 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28912557/a-nmda-receptor-calcium-influx-assay-sensitive-to-stimulation-by-glutamate-and-glycine-d-serine
#15
Hongqiu Guo, L Miguel Camargo, Fred Yeboah, Mary Ellen Digan, Honglin Niu, Yue Pan, Stephan Reiling, Gilberto Soler-Llavina, Wilhelm A Weihofen, Hao-Ran Wang, Y Gopi Shanker, Travis Stams, Anke Bill
N-methyl-D-aspartate-receptors (NMDARs) are ionotropic glutamate receptors that function in synaptic transmission, plasticity and cognition. Malfunction of NMDARs has been implicated in a variety of nervous system disorders, making them attractive therapeutic targets. Overexpression of functional NMDAR in non-neuronal cells results in cell death by excitotoxicity, hindering the development of cell-based assays for NMDAR drug discovery. Here we report a plate-based, high-throughput approach to study NMDAR function...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912219/news-at-a-glance
#16
John Travis
No abstract text is available yet for this article.
September 15, 2017: Science
https://www.readbyqxmd.com/read/28910820/prospective-investigation-of-risk-factors-for-prostate-cancer-in-the-uk-biobank-cohort-study
#17
Aurora Perez-Cornago, Timothy J Key, Naomi E Allen, Georgina K Fensom, Kathryn E Bradbury, Richard M Martin, Ruth C Travis
BACKGROUND: Prostate cancer is the most common cancer in British men but its aetiology is not well understood. We aimed to identify risk factors for prostate cancer in British males. METHODS: We studied 219 335 men from the UK Biobank study who were free from cancer at baseline. Exposure data were collected at recruitment. Prostate cancer risk by the different exposures was estimated using multivariable-adjusted Cox proportional hazards models. RESULTS: In all, 4575 incident cases of prostate cancer occurred during 5...
September 14, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28910427/epidemiology-of-conjunctivitis-in-us-emergency-departments
#18
David A Ramirez, Travis C Porco, Thomas M Lietman, Jeremy D Keenan
No abstract text is available yet for this article.
September 14, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28905717/use-of-liposomal-bupivacaine-for-postoperative-analgesia-in-an-incisional-pain-model-in-rats-rattus-norvegicus
#19
Stacey C Kang, Katechan Jampachaisri, Travis L Seymour, Stephen A Felt, Cholawat Pacharinsak
The local anesthetic bupivacaine is valuable for perioperative analgesia, but its use in the postoperative period is limited by its short duration of action. Here, we evaluated the application of a slow-release liposomal formulation of bupivacaine for postoperative analgesia. The aim was to assess whether liposomal bupivacaine effectively attenuates postoperative mechanical and thermal hypersensitivity in a rat model of incisional pain. Rats (n = 36) were randomly assigned to 1 of 5 treatment groups: saline, 1 mL/kg SC every 12 h for 2 d; buprenorphine HCl, 0...
January 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28905233/gated-thoracic-magnetic-resonance-angiography-at-3t-noncontrast-versus-blood-pool-contrast
#20
Chengcheng Zhu, Henrik Haraldsson, Kimberly Kallianos, Liang Ge, Elaine Tseng, Travis Henry, David Saloner, Michael D Hope
Both noncontrast and contrast-enhanced approaches to gated thoracic magnetic resonance angiography (MRA) for aortic root evaluation have been reported at 3T. We compare qualitative and quantitative image quality measures for the two approaches, and assess the reproducibility of standard aortic measurements. Respiratory and cardiac gated MRA of the chest was performed at 3T in 45 patients: 23 after administration of iron-based blood pool contrast, and 22 without contrast. Image quality was assessed with a 5-point Likert scale, vessel lumen-to-muscle contrast ratios, and vessel wall sharpness...
September 13, 2017: International Journal of Cardiovascular Imaging
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