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https://www.readbyqxmd.com/read/28740862/giant-convecting-mud-balls-of-the-early-solar-system
#1
Philip A Bland, Bryan J Travis
Carbonaceous asteroids may have been the precursors to the terrestrial planets, yet despite their importance, numerous attempts to model their early solar system geological history have not converged on a solution. The assumption has been that hydrothermal alteration was occurring in rocky asteroids with material properties similar to meteorites. However, these bodies would have accreted as a high-porosity aggregate of igneous clasts (chondrules) and fine-grained primordial dust, with ice filling much of the pore space...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28740585/testosterone-and-the-heart
#2
Travis Goodale, Archana Sadhu, Steven Petak, Richard Robbins
Testosterone (T) has a number of important effects on the cardiovascular system. In men, T levels begin to decrease after age 40, and this decrease has been associated with an increase in all-cause mortality and cardiovascular (CV) risk. Low T levels in men may increase their risk of developing coronary artery disease (CAD), metabolic syndrome, and type 2 diabetes. Reduced T levels in men with congestive heart failure (CHF) portends a poor prognosis and is associated with increased mortality. Studies have reported a reduced CV risk with higher endogenous T concentration, improvement of known CV risk factors with T therapy, and reduced mortality in T-deficient men who underwent T replacement therapy versus untreated men...
April 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/28739524/social-instability-stress-in-adolescent-male-rats-reduces-social-interaction-and-social-recognition-performance-and-increases-oxytocin-receptor-binding
#3
Travis E Hodges, Jennet L Baumbach, Marina L Marcolin, Remco Bredewold, Alexa H Veenema, Cheryl M McCormick
Social experiences in adolescence are essential for displaying context-appropriate social behaviours in adulthood. We previously found that adult male rats that underwent social instability stress (SS) in adolescence had reduced social interactions with unfamiliar peers compared with non-stressed controls (CTL). Here we determined whether SS altered social recognition and social reward and brain oxytocin and vasopressin receptor density in adolescence. We confirmed that SS rats spent less time interacting with unfamiliar peers than did CTL rats (p = 0...
July 21, 2017: Neuroscience
https://www.readbyqxmd.com/read/28739321/preventing-intravenous-contrast-extravasation-in-ct-a-simple-solution
#4
Brandy Conner, Ryan Ash, Wendy Allen, Travis Brown, Jacqueline Hill, Marcus Hook, Shelby Fishback
No abstract text is available yet for this article.
July 21, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28738947/outpatient-total-thyroidectomy-is-safe-for-moderate-volume-surgeons
#5
Jonathan Black, Travis Cotton, Jen Jen Yeh
Traditionally, total thyroidectomy (TT) was an inpatient procedure, but recent trends indicate that patients are often discharged on the day of surgery. This has been proven safe for high-volume surgeons but has not been studied for low (<10 TT per year) and moderate volume surgeons (<24 TT per year). Retrospective review was performed for 414 total thyroidectomies between 2005 and 2013. Emergency department visits and readmissions within 30 days of surgery were captured, but were considered the same for the purpose of this analysis...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738944/predicting-postoperative-complications-for-acute-care-surgery-patients-using-the-acs-nsqip-surgical-risk-calculator
#6
Jessica R Burgess, Benjamin Smith, Rebecca Britt, Leonard Weireter, Travis Polk
The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) risk calculator has been used to assist surgeons in predicting the risk of postoperative complications. This study aims to determine if the risk calculator accurately predicts complications in acute care surgical patients undergoing laparotomy. A retrospective review was performed on all patients on the acute care surgery service at a tertiary hospital who underwent laparotomy between 2011 and 2012. The preoperative risk factors were used to calculate the estimated risks of postoperative complications in both the original ACS NSQIP calculator and updated calculator (June 2016)...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738082/short-term-sleep-deprivation-leads-to-decreased-systemic-redox-metabolites-and-altered-epigenetic-status
#7
Malav S Trivedi, Dana Holger, Anh Tuyet Bui, Travis J A Craddock, Jaime L Tartar
Sleep is critical for repair as well as the rejuvenation processes in the body and many of these functions are regulated via underlying cellular metabolic homeostasis. Changes in sleep pattern are reported to alter such metabolic function resulting in altered disease susceptibility or behavior. Here, we measured the extent to which overnight total sleep deprivation (SD) in young adult humans can influence systemic (plasma-derived) redox-metabolism including the major antioxidant, glutathione as well as DNA methylation levels...
2017: PloS One
https://www.readbyqxmd.com/read/28737530/ultrasound-characteristics-of-clinically-dislocated-but-reducible-hips-with-ddh
#8
Brendan Striano, Emily K Schaeffer, Travis H Matheney, Vidayadhar V Upasani, Charles T Price, Kishore Mulpuri, Wudbhav N Sankar
BACKGROUND: Although ultrasound (US) is frequently used in diagnosis and management of infantile developmental dysplasia of the hip, precise ultrasonographic parameters of what constitutes a dislocation, subluxation etc remain poorly defined. The purpose of this study was (1) to describe the ultrasonographic characteristics of a large cohort of clinically dislocated but reducible hips and (2) to begin to develop ultrasonographic definitions for what constitutes a hip dislocation. METHODS: A retrospective review of prospectively collected data from an international multicenter study group on developmental dysplasia of the hip was conducted on all patients under 6 months of age with hip(s) that were dislocated at rest but reducible based on initial physical examination (ie, Ortolani positive)...
July 21, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28736349/completion-of-the-circle-of-willis-varies-by-gender-age-and-indication-for-cta
#9
Orel A Zaninovich, Wyatt L Ramey, Christina M Walter, Travis M Dumont
OBJECTIVE: The Circle of Willis (CoW) is the foremost anastomosis and blood distribution center of the brain. Its effectiveness depends on its completion and the size and patency of its vessels. Gender- and age-related anatomical variations in the CoW may play an important role in the pathogenesis of cerebrovascular diseases. In this study, we analyzed CT angiograms to assess for differences in CoW completion related to gender, age, and indication for CTA. METHODS: 834 CTAs were retrospectively analyzed for all CoW vessels to compare the incidence of complete CoW and variation frequency based on gender, age, and indication...
July 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28736204/neural-stability-a-reflection-of-automaticity-in-reading
#10
Silvia Siu-Yin Lam, Travis White-Schwoch, Steven G Zecker, Jane Hornickel, Nina Kraus
Automaticity, the ability to perform a task rapidly with minimal effort, plays a key role in reading fluency and is indexed by rapid automatized naming (RAN) and processing speed. Yet little is known about automaticity's neurophysiologic underpinnings. The more efficiently sound is encoded, the more automatic sound processing can be. In turn, this automaticity could free up cognitive resources such as attention and working memory to help build an integrative reading network. Therefore, we hypothesized that automaticity and reading fluency correlate with stable neural representation of sounds, given a larger body of literature suggesting the close relationship between neural stability and the integrative function in the central auditory system...
July 20, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28731829/pattern-and-process-in-the-comparative-study-of-convergent-evolution
#11
D Luke Mahler, Marjorie G Weber, Catherine E Wagner, Travis Ingram
Understanding processes that have shaped broad-scale biodiversity patterns is a fundamental goal in evolutionary biology. The development of phylogenetic comparative methods has yielded a tool kit for analyzing contemporary patterns by explicitly modeling processes of change in the past, providing neontologists tools for asking questions previously accessible only for select taxa via the fossil record or laboratory experimentation. The comparative approach, however, differs operationally from alternative approaches to studying convergence in that, for studies of only extant species, convergence must be inferred using evolutionary process models rather than being directly measured...
August 2017: American Naturalist
https://www.readbyqxmd.com/read/28730972/aoac-smpr-%C3%A2-2017-011-standard-method-performance-requirements-smprs-for-identification-and-quantitation-of-free-alpha-amino-acids-in-dietary-ingredients-and-supplements
#12
Garrett Zielinski, Gisele Atkinson, Sneh Bhandari, Paul Burns, Danielle Citrolo, Christine Farthing, Brandi Glover, Adam Horkey, Holly Johnson, Adam Kuszak, Jeff Lin, J Andreas Lippert, Elizabeth Mudge, Maria Ofitserova, Lars M Reimann, Aniko M Solyom, Darryl M Sullivan, John Szpylka, John Travis, Jason Lynn Wubben, Jinchuan Yang, Hong You, Kurt Young, Scott G Coates
No abstract text is available yet for this article.
July 21, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28729062/pharmacological-activation-of-ampk-inhibits-incision-evoked-mechanical-hypersensitivity-and-the-development-of-hyperalgesic-priming-in-mice
#13
Michael D Burton, Dipti V Tillu, Khadijah Mazhar, Galo L Mejia, Marina N Asiedu, Kufreobong Inyang, Travis Hughes, Bo Lian, Gregory Dussor, Theodore J Price
New therapeutics to manage post-surgical pain are needed to mitigate the liabilities of opioid and other analgesics. Our previous work shows that key modulators of excitability in peripheral nociceptors, such as extracellular signal-regulated kinases (ERK) are inhibited by activation of adenosine monophosphate activated protein kinase (AMPK). We hypothesized that AMPK activation would attenuate acute incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming caused by surgery in mice...
July 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28727858/association-of-velopharyngeal-insufficiency-with-quality-of-life-and-patient-reported-outcomes-after-speech-surgery
#14
Aditi Bhuskute, Jonathan R Skirko, Christina Roth, Ahmed Bayoumi, Blythe Durbin-Johnson, Travis T Tollefson
Importance: Patients with cleft palate and other causes of velopharyngeal insufficiency (VPI) suffer adverse effects on social interactions and communication. Measurement of these patient-reported outcomes is needed to help guide surgical and nonsurgical care. Objectives: To further validate the VPI Effects on Life Outcomes (VELO) instrument, measure the change in quality of life (QOL) after speech surgery, and test the association of change in speech with change in QOL...
July 20, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28727610/the-metabolopathy-of-tissue-injury-hemorrhagic-shock-and-resuscitation-in-a-rat-model
#15
Anne L Slaughter, Geoffrey R Nunns, Angelo D'Alessandro, Anirban Banerjee, Kirk C Hansen, E E Moore, Christopher C Silliman, Travis Nemkov, Hunter B Moore, Miguel Fragoso, Kiara Leasia, Erik D Peltz
INTRODUCTION: The metabolic consequences of trauma induce significant clinical pathology. In this study we evaluate the independent, metabolic contributions of tissue injury (TI) and combined tissue injury and hemorrhagic shock (TI / HS) using MS-metabolomics in a controlled animal model of critical injury. METHODS: Sprague-Dawley rats (n = 14) underwent TI alone or TI / HS, followed by resuscitation with normal saline and shed blood. Plasma was collected (baseline, post-laparotomy, post-HS, post-resuscitation) for Ultra High Pressure Liquid Chromatography (UHPLC) MS-metabolomics...
July 19, 2017: Shock
https://www.readbyqxmd.com/read/28726603/clinical-laboratory-values-as-early-indicators-of-ebola-virus-infection-in-nonhuman-primates
#16
Ronald B Reisler, Chenggang Yu, Michael J Donofrio, Travis K Warren, Jay B Wells, Kelly S Stuthman, Nicole L Garza, Sean A Vantongeren, Ginger C Donnelly, Christopher D Kane, Mark G Kortepeter, Sina Bavari, Anthony P Cardile
The Ebola virus (EBOV) outbreak in West Africa during 2013-2016 demonstrated the need to improve Ebola virus disease (EVD) diagnostics and standards of care. This retrospective study compared laboratory values and clinical features of 3 nonhuman primate models of lethal EVD to assess associations with improved survival time. In addition, the study identified laboratory values useful as predictors of survival, surrogates for EBOV viral loads, and triggers for initiation of therapeutic interventions in these nonhuman primate models...
August 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28726312/spinal-cord-stimulator-related-infections-findings-from-a-multicenter-retrospective-analysis-of-2737-implants
#17
Markus A Bendel, Travis O'Brien, Bryan C Hoelzer, Timothy R Deer, Thomas P Pittelkow, Shrif Costandi, David R Walega, Gerges Azer, Salim M Hayek, Zhen Wang, Jason S Eldrige, Wenchun Qu, Joshua M Rosenow, Steven M Falowski, Stephanie A Neuman, Susan M Moeschler, Catherine Wassef, Christopher Kim, Tariq Niazi, Taher Saifullah, Brian Yee, Chong Kim, Christine L Oryhan, Daniel T Warren, Imanuel Lerman, Ruben Mora, Michael Hanes, Thomas Simopoulos, Sanjiv Sharma, Chris Gilligan, Warren Grace, Timothy Ade, Nagy A Mekhail, John P Hunter, Daniel Choi, Deborah Y Choi
INTRODUCTION: Surgical site infection is a potential complication of spinal cord stimulator (SCS) implantation. Current understanding of the epidemiology, diagnosis, and treatment of these infections is based largely on small clinical studies, many of which are outdated. Evidence-based guidelines for management of SCS-related infections thus rely instead on expert opinion, case reports, and case series. In this study, we aim to provide a large scale retrospective study of infection management techniques specifically for SCS implantation...
July 20, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28725840/the-impact-of-revised-discharge-instructions-on-patient-satisfaction
#18
Heather Markey Waniga, Travis Gerke, Alena Shoemaker, Derek Bourgoine, Pracha Eamranond
INTRODUCTION: The impact of discharge instructions on a patient's experience is not fully understood. This research explored whether nurse- and physician-generated discharge instructions had a positive effect on patient perceptions regarding their discharge experience. METHODS: We compared Press Ganey discharge-related patient satisfaction scores for the year prior to and the year subsequent to implementing revised discharge instructions for all patients admitted to a 180-bed community-based hospital...
September 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28722569/mass-azithromycin-and-malaria-parasitemia-in-niger-results-from-a-community-randomized-trial
#19
Kieran S O'Brien, Sun Y Cotter, Abdou Amza, Boubacar Kadri, Baido Nassirou, Nicole E Stoller, Zhaoxia Zhou, Chris Cotter, Sheila K West, Robin L Bailey, Philip J Rosenthal, Bruce D Gaynor, Travis C Porco, Thomas M Lietman
Studies designed to determine the effects of mass administration of azithromycin on trachoma have suggested that mass azithromycin distributions may also reduce the prevalence of malaria. These studies have typically examined the impact of a small number of treatments over short durations. In this prespecified substudy of a cluster-randomized trial for trachoma, we compared malaria parasitemia prevalence in 24 communities in Niger randomized to receive either annual or biannual mass azithromycin distributions over 3 years...
June 19, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28720857/population-variation-in-the-trophic-niche-of-the-trinidadian-guppy-from-different-predation-regimes
#20
Eugenia Zandonà, Christopher M Dalton, Rana W El-Sabaawi, Jason L Howard, Michael C Marshall, Susan S Kilham, David N Reznick, Joseph Travis, Tyler J Kohler, Alexander S Flecker, Steven A Thomas, Catherine M Pringle
Population variation in trophic niche is widespread among organisms and is of increasing interest given its role in both speciation and adaptation to changing environments. Trinidadian guppies (Poecilia reticulata) inhabiting stream reaches with different predation regimes have rapidly evolved divergent life history traits. Here, we investigated the effects of both predation and resource availability on guppy trophic niches by evaluating their gut contents, resource standing stocks, and δ(15)N and δ(13)C stable isotopes across five streams during the wet season...
July 18, 2017: Scientific Reports
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