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Cox Maze

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https://www.readbyqxmd.com/read/27909520/surgical-ablation-of-atrial-fibrillation-is-electrical-isolation-of-the-pulmonary-veins-a-must
#1
REVIEW
Bart Maesen Md PhD, Ines Van Loo Md, Laurent Pison Md PhD, Mark La Meir Md PhD
Ablation of atrial fibrillation (AF) is a well-established treatment option for patients with symptomatic AF refractory to antiarrhythmic drugs. The cornerstone of catheter ablation is electrical isolation of the pulmonary veins, since the pulmonary veins are the most common location for triggers of AF. Electrical reconnection of the pulmonary veins is associated with arrhythmia recurrence and therefore diminishes long-term success of catheter ablation of AF. Therefore, durable pulmonary vein isolation remains a condition sine qua non for catheter ablation of AF...
June 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27873505/hyperbaric-oxygen-pretreatment-improves-cognition-and-reduces-hippocampal-damage-via-p38-mitogen-activated-protein-kinase-in-a-rat-model
#2
Baisong Zhao, Yongying Pan, Zixin Wang, Haiping Xu, Xingrong Song
PURPOSE: To investigate the effects of hyperbaric oxygen (HBO) pretreatment on cognitive decline and neuronal damage in an Alzheimer's disease (AD) rat model. MATERIALS AND METHODS: Rats were divided into three groups: normal saline (NS), AD, and HBO+AD. In the AD group, amyloid β peptide (Aβ)₁₋₄₀ was injected into the hippocampal CA1 region of the brain. NS rats received NS injection. In the HBO+AD group, rats received 5 days of daily HBO therapy following Aβ₁₋₄₀ injection...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27854045/development-of-the-maze-procedure-and-the-contribution-of-japanese-surgeons
#3
REVIEW
Shinya Takahashi, Taijiro Sueda
OBJECTIVE: The Cox-Maze procedure is the most popular surgical procedure in the world for eliminating atrial fibrillation (AF). Japanese surgeons performed and modified its procedure. This review describes the concept of the Maze procedure, modifications of the Maze procedure and findings related to the Maze procedure obtained by Japanese surgeons. METHODS: Original Cox-Maze procedures and modified Maze procedures developed by Japanese surgeons were reviewed chronologically...
November 16, 2016: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27832044/early-results-of-the-modified-right-atrial-lesion-set-for-the-cox-cryomaze-procedure
#4
Faisal Habib Cheema, Muhammad Amir Younus, Osama T Siddiqui, Muhammad Jabran Younus, Muhammad Arif Mahmood, Mohammad Bin Pervez, Harold G Roberts
OBJECTIVE: The standard right atrial lesion (RAL) set, as originally outlined in the Cox-Maze III procedure, can be technically challenging when using a cryoprobe to create the lesions. We report our initial experience with an alternative set of RALs for the surgical treatment of atrial fibrillation (AF). METHODS: Between September 2011 and January 2015, a total of 112 patients underwent a CryoMaze procedure with biatrial lesions using argon-based cryoablation (cryoprobe temperature, -160°C)...
September 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27747025/atrial-fibrillation-review-of-current-treatment-strategies
#5
Joshua Xu, Jessica G Y Luc, Kevin Phan
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in modern clinical practice, with an estimated prevalence of 1.5-2%. The prevalence of AF is expected to double in the next decades, progressing with age and increasingly becoming a global medical challenge. The first-line treatment for AF is often medical treatment with either rate control or anti-arrhythmic agents for rhythm control, in addition to anti-coagulants such as warfarin for stroke prevention in patient at risk. Catheter ablation has emerged as an alternative for AF treatment, which involves myocardial tissue lesions to disrupt the underlying triggers and substrates for AF...
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27738072/surgery-for-supraventricular-tachycardia-and-congenital-heart-defects-long-term-efficacy-of-the-combined-approach-in-adult-patients
#6
Alessandro Giamberti, Francesca R Pluchinotta, Massimo Chessa, Alessandro Varrica, Raffaele Vitale, Alessandro Frigiola, Carlo Pappone, Marco Ranucci
AIMS: Supraventricular arrhythmias are a major cause of morbidity and mortality in adult patients with congenital heart disease (CHD). Intraoperative ablation offers an alternative for patients who failed ablation procedures or are requiring concomitant surgical intervention. We present our long-term results with the surgical treatment of arrhythmias in adults with CHD (ACHD) undergoing elective cardiac surgery and the clinical predictors for arrhythmia recurrence. METHODS AND RESULTS: Between 2002 and 2013, 80 consecutive patients with CHD, mean age of 39 years, underwent intraoperative ablation with monopolar irrigated radiofrequency during cardiac surgery procedures...
October 12, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27730514/intranasal-insulin-administration-ameliorates-streptozotocin-icv-induced-insulin-receptor-dysfunction-neuroinflammation-amyloidogenesis-and-memory-impairment-in-rats
#7
N Rajasekar, Chandishwar Nath, Kashif Hanif, Rakesh Shukla
Alzheimer's disease (AD) is associated with reduced insulin level and impairment of insulin receptor (IR) signaling in the brain, which correlates to amyloid pathology, neuroinflammation, and synaptic neurotoxicity. Clinical studies show that intranasal insulin improves memory in AD patients without peripheral hypoglycemia. However, neuroprotective molecular mechanism of the beneficial effect of intranasal insulin in AD pathology is unexplored. Therefore, we investigated the role of intranasal insulin on intracerebroventricular (ICV) streptozotocin (STZ)-induced memory impairment in rats as evaluated in the Morris water maze test...
October 11, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27664426/the-totally-thoracoscopic-maze-procedure-for-the-treatment-of-atrial-fibrillation
#8
Charlotte van Laar, Johannes Kelder, Bart P van Putte
The purpose of this study was to update the current evidence regarding the efficacy and safety of the totally thoracoscopic maze (TT-maze) procedure for the treatment of atrial fibrillation (AF). Fourteen studies published between 2011 and 2016 and comprising 1171 patients were included as follows: 545 (46%) patients had paroxysmal AF (pAF), 268 (23%) persistent AF (persAF) and 358 (31%) longstanding persistent AF (LSPAF). Fixed- and random-effect models were used to calculate the pooled overall freedom from atrial arrhythmias...
September 23, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27558131/persistent-atrial-standstill-following-the-cox-maze-iii-procedure-reversal-with-sustained-atrial-pacing
#9
Harsh Agrawal, Kul Aggarwal, Martin A Alpert
Atrial standstill is a rare disorder of cardiac rhythm that is characterized by total absence of electrical activity in one or both atria. We report herein the case of a patient with atrial fibrillation and symptomatic 4.0 s pauses who received a ventricular demand pacemaker. The patient later underwent mitral valve replacement with a pericardial tissue valve and the Cox-maze III procedure for symptomatic mitral stenosis and atrial fibrillation. Following surgery, he developed atrial standstill and became pacemaker dependent...
August 25, 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/27544292/left-sided-surgical-ablation-for-patients-with-atrial-fibrillation-who-are-undergoing-concomitant-cardiac-surgical-procedures
#10
Niv Ad, Sari D Holmes, Deborah Lamont, Deborah J Shuman
BACKGROUND: Growing evidence indicates the effectiveness of surgical ablation confined to the left atrium, especially with short duration of atrial fibrillation (AF) and smaller left atrial (LA) size. This study examined rhythm status and predictors of failure in this group of patients. METHODS: Of 800 patients who underwent concomitant surgical ablation (2005 to 2015), 110 had LA-only ablation. Rhythm status was defined according to Heart Rhythm Society guidelines: sinus rhythm (SR) without class I/III antiarrhythmic drugs (AADs)...
August 17, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27521177/a-modified-cox-maze-iv-procedure-a-simpler-technique-for-the-surgical-treatment-of-atrial-fibrillation
#11
Jun Shi, Zhi-Xuan Bai, Ben-Gui Zhang, Wen-Jun Ren, Ying-Qiang Guo
OBJECTIVES: To determine the effectiveness of a simplified surgical treatment method for atrial fibrillation (AF). METHODS: Between September 2012 and October 2013, 120 patients (mean age, 52.3 ± 8.8 years) underwent valve surgery and concomitant bipolar radiofrequency ablation for the treatment of AF. Patients were randomized to a Cox maze IV procedure (CMP-IV) group (n = 60) or a modified CMP-IV (MCMP-IV) group (n = 60). Freedom from AF was defined as freedom from any left atrial arrhythmia lasting <30 s and no requirement of antiarrhythmic drugs after 6 months...
August 11, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27488281/redefining-the-role-of-peripheral-lps-as-a-neuroinflammatory-agent-and-evaluating-the-role-of-hydrogen-sulphide-through-metformin-intervention
#12
Virendra Tiwari, Manjari Singh, Jitendra K Rawat, Uma Devi, Rajnish K Yadav, Subhadeep Roy, Swetlana Gautam, Shubhini A Saraf, Vikas Kumar, Nazam Ansari, Abdulaziz S Saeedan, Gaurav Kaithwas
OBJECTIVE: The present study was aimed to enumerate the role of metformin-associated H2S release against lipopolysaccharide (LPS) induced neuroinflammation. MATERIALS AND METHODS: Five groups of animals were subjected to treatment as control (normal saline), toxic control (LPS, 125 µg/kg, i.p.), and three separate groups treated with 6.25, 12.5, and 25 mg/kg of metformin along with LPS for a period of 28 days. LPS was administered on 1st, 2nd, 3rd, 4th, 23rd, 24th, 25th and 26th day...
October 2016: Inflammopharmacology
https://www.readbyqxmd.com/read/27349157/outcomes-of-surgical-ablation-for-atrial-fibrillation-a-10-year-experience
#13
Andrew J Borrie, Brecon H Wademan
AIM: Surgical ablation for atrial fibrillation has been performed at Wellington hospital for 10 years. This audit aims to evaluate the outcomes from surgical intervention for atrial fibrillation and identify variables affecting clinical results. METHOD: A retrospective audit of clinical outcomes was performed including all patients who had received surgical intervention for atrial fibrillation from 2004 to 2013. RESULTS: Forty-seven patients who underwent surgical intervention for atrial fibrillation were identified and reviewed...
2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27325346/fix-what-is-broken-scar-homogenization-in-persistent-atrial-fibrillation
#14
Karoly Kaszala, Kenneth A Ellenbogen
No abstract text is available yet for this article.
September 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27276653/silibinin-rescues-learning-and-memory-deficits-by-attenuating-microglia-activation-and-preventing-neuroinflammatory-reactions-in-samp8-mice
#15
Ge Jin, Dafeng Bai, Shiliang Yin, Zhihang Yang, Dan Zou, Zhong Zhang, Xiaoxiu Li, Yan Sun, Qiwen Zhu
Silibinin was reported to be effective in reversing the learning and memory deficits of several AD animal models. These improvements are thought to be regulated by various factors, including antioxidative stress, inhibition of acetylcholinesterase activity and Aβ aggregation. However, there are still no reports that demonstrate the effect of silibinin on microglia activation in vivo. Thus, in this study, we used the senescence-accelerated mouse (SAMP8) strain to test the effects of silibinin on behavioral impairments and microglia activation-induced neuroinflammation...
August 26, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27262176/gender-differences-in-management-and-clinical-outcomes-of-atrial-fibrillation-patients
#16
Natasha A Kassim, Andrew D Althouse, Dingxin Qin, George Leef, Samir Saba
BACKGROUND: Prior research has identified gender differences in the epidemiology and clinical management of atrial fibrillation (AF). The primary aim of this study is to systematically analyze a cohort of AF men and women and evaluate their baseline demographics, treatment, and clinical outcomes by gender. METHODS: We examined the records of 5976 (42% women) consecutive AF patients who were prescribed at least one anti-arrhythmic drug between 2006 and 2013. From this cohort, 4311 (72%) patients had anticoagulation data available and were included in the final analysis...
June 1, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27248647/cox-maze-iv-cryoablation-and-postoperative-heart-failure-in-mitral-valve-surgery-patients
#17
Gabriella Boano, Meriam Åström Aneq, Jennie Kemppi, Farkas Vánky
OBJECTIVE: The indications for and the risk and benefit of concomitant surgical ablation for atrial fibrillation (AF) have not been fully delineated. Our aim was to survey whether the Cox-maze IV procedure is associated with postoperative heart failure (PHF) or other adverse short-term outcomes after mitral valve surgery (MVS). DESIGN: Consecutive patients with AF undergoing MVS with (n = 50) or without (n = 66) concomitant Cox-maze IV cryoablation were analysed regarding perioperative data and one-year mortality...
June 16, 2016: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/27212634/severe-systolic-anterior-motion-after-aortic-valve-replacement-and-cox-maze-surgery
#18
Corstiaan A den Uil, Maarten Ter Horst, Sakir Akin, Tjebbe W Galema
Surgical aortic valve replacement may be complicated by severe dynamic left ventricular outflow tract obstruction and cardiogenic shock in the postoperative period. We present a patient who developed severe anterior motion following aortic valve and Cox MAZE surgery which necessitated a mitral valve replacement. doi: 10.1111/jocs.12763 (J Card Surg 2016;31:429-431).
July 2016: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/27211963/a-modified-epicardial-radiofrequency-ablation-for-preoperative-atrial-fibrillation-combined-with-isolated-aortic-valve-disease
#19
Zhaolei Jiang, Nan Ma, Hao Liu, Min Tang, Fangbao Ding, Chunrong Bao, Ju Mei
Isolated aortic valve diseases can lead to atrial fibrillation (AF) by causing left atrium pressure overload and enlargement. At present, most patients with preoperative AF and isolated aortic valve disease have undergone a Cox-maze IV procedure through a left atriotomy under cardiopulmonary bypass with aortic cross-clamping. Here, we describe a novel modified epicardial radiofrequency ablation procedure performed on a beating heart without aortic cross-clamping or opening the left atrium. This technique has proved to be safe and feasible, with good clinical outcomes...
June 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27164468/cerebrolysin-improves-memory-and-ameliorates-neuronal-atrophy-in-spontaneously-hypertensive-aged-rats
#20
Carlos Solis-Gaspar, Ruben A Vazquez-Roque, Ma De Jesús Gómez-Villalobos, Gonzalo Flores
The spontaneously hypertensive (SH) rat has been used as an animal model of vascular dementia (VD). Our previous report showed that, SH rats exhibited dendritic atrophy of pyramidal neurons of the CA1 dorsal hippocampus and layers 3 and 5 of the prefrontal cortex (PFC) at 8 months of age. In addition, we showed that cerebrolysin (Cbl), a neurotrophic peptide mixture, reduces the dendritic atrophy in aged animal models. This study aimed to determine whether Cbl was capable of reducing behavioral and neuronal alterations, in old female SH rats...
September 2016: Synapse
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