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Spina bifida

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https://www.readbyqxmd.com/read/27904817/transitional-vertebra-and-spina-bifida-occulta-related-with-chronic-low-back-pain-in-a-young-patient
#1
Maryam Kundi, Maham Habib, Sumbal Babar, Asif K Kundi, Salman Assad, Amjad Sheikh
Bertolotti's syndrome (BS) must be considered as a differential diagnosis in a young patient presenting with low back pain (LBP). We present a case of a 26-year-old male complaining of mild chronic LBP for six years, radiating to his left thigh for the past six months. He has been taking non-steroidal anti-inflammatory drugs (NSAIDs) with skeletal muscle relaxants for pain relief. The X-ray and computed tomography (CT) imagings showed congenital enlargement of the left transverse process of the fifth lumbar (L5) vertebra forming pseudo-articulation with the sacrum and unilateral pars interarticularis defect at the L4 level on the left side, respectively...
October 19, 2016: Curēus
https://www.readbyqxmd.com/read/27891778/paternal-and-joint-parental-occupational-pesticide-exposure-and-spina-bifida-in-the-national-birth-defects-prevention-study-1997-to-2002
#2
Stacy M Pettigrew, Erin M Bell, Alissa R Van Zutphen, Carissa M Rocheleau, Gary M Shaw, Paul A Romitti, Andrew Olshan, Philip J Lupo, Aida Soim, Jennifer A Makelarski, Adrian M Michalski, Wayne Sanderson
BACKGROUND: Because of persistent concerns over the association between pesticides and spina bifida, we examined the role of paternal and combined parental occupational pesticide exposures in spina bifida in offspring using data from a large population-based study of birth defects. METHODS: Occupational information from fathers of 291 spina bifida cases and 2745 unaffected live born control infants with estimated dates of delivery from 1997 to 2002 were collected by means of maternal report...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27883265/genomic-approaches-to-the-assessment-of-human-spina-bifida-risk
#3
REVIEW
M Elizabeth Ross, Christopher E Mason, Richard H Finnell
Structural birth defects are a leading cause of mortality and morbidity in children world-wide, affecting as much as 6% of all live births. Among these conditions, neural tube defects (NTDs), including spina bifida and anencephaly, arise from a combination of complex gene and environment interactions that are as yet poorly understood within human populations. Rapid advances in massively parallel DNA sequencing and bioinformatics allow for analyses of the entire genome beyond the 2% of the genomic sequence covering protein coding regions...
November 24, 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27881468/elevated-ambient-temperatures-and-risk-of-neural-tube-defects
#4
Nathalie Auger, William D Fraser, Laura Arbour, Marianne Bilodeau-Bertrand, Tom Kosatsky
OBJECTIVES: The association between ambient heat and neural tube defects has received limited attention, despite imminent climate warming this century. We sought to determine the relationship between elevated outdoor temperatures during neurogenesis and risk of neural tube defects. METHODS: We carried out a retrospective cohort study of 887 710 fetuses between 3 and 4 weeks postconception from the months of April through September for 1988-2012 in Quebec, Canada...
November 22, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27878110/discontinuation-of-antimicrobial-prophylaxis-ap-in-children-with-spina-bifida-a-case-series-analysis
#5
Kevin G Couloures, Michael Anderson, Michael Machiorlatti, Olivera Marsenic, Lawrence Opas
BACKGROUND: Spina bifida increases the risk for urinary tract infections (UTI). Antimicrobial prophylaxis (AP) reduces symptomatic UTI's but selects resistant organisms. Measures to ensure regular and complete emptying of the bladder combined with treatment of constipation reduce the risk for UTI. OBJECTIVES: Demonstrate that close adherence to a catheterization regimen in children with spina bifida (Selective Treatment - ST) reduces the need for antimicrobial prophylaxis...
September 2016: Nephro-urology Monthly
https://www.readbyqxmd.com/read/27875931/early-numeracy-skills-in-preschool-aged-children-a-review-of-neurocognitive-findings-and-implications-for-assessment-and-intervention
#6
Kimberly P Raghubar, Marcia A Barnes
OBJECTIVES: The goals are to (1) provide a review of the typical and atypical development of early numeracy; (2) present what is known about the neurocognitive underpinnings of early numeracy; and (3) discuss the implications for early assessment and intervention. METHOD: Studies on the development of typical and atypical early numeracy are reviewed with a particular focus on longitudinal findings including those from our work on spina bifida myelomeningocele. Implications of this research for assessment are presented...
November 23, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27875031/prevalence-of-neural-tube-defects-in-a-rural-area-of-north-india-from-2001-to-2014-a-population-based-survey
#7
Shashi Kant, Sumit Malhotra, Arvind Kumar Singh, Partha Haldar, Ravneet Kaur, Puneet Misra, Neerja Gupta
BACKGROUND: Neural tube defects (NTDs) are one of the commonest birth defects. There was paucity of community-based data on occurrence of NTDs in India, especially from rural parts of the country. Against this background, the current study was carried out with main objectives to determine the prevalence of NTDs and its specific types (anencephaly, spina bifida and encephalocele) in a rural community setting over the time period 2001 to 2014. METHODS: This was a community-based cross-sectional study carried out in 28 villages of Ballabgarh Tehsil of Faridabad district in north India (population ∼ 96,000)...
November 22, 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27868580/attention-lapses-in-children-with-spina-bifida-and-hydrocephalus-and-children-with-attention-deficit-hyperactivity-disorder
#8
Gabriel G De la Torre, Alba Martin, Elizabeth Cervantes, Rocio Guil, Jose M Mestre
Attentional lapses are usually defined as temporary and often brief shifts of attention away from some primary task to unrelated internal information processing. This study addressed the incidence of attention lapses and differences in attentional functioning in 30 children with attention-deficit/hyperactivity disorder (ADHD), 26 healthy children, and 29 children with spina bifida myelomeningocele and hydrocephalus (SBH). Assessments were conducted using computerized tonic and phasic attention tests, the Symbol Digit Modalities Test (SDMT), and the Trail Making Test Form B (TMT-B)...
November 20, 2016: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/27862592/retrograde-continence-enema-in-children-with-spina-bifida-not-as-effective-as-first-thought
#9
Sebastian K King, Lefteris Stathopoulos, Loreto Pinnuck, Judy Wells, John Hutson, Yves Heloury
AIM: The aim of the study is to investigate the effectiveness of Peristeen retrograde continence enema (RCE) in the management of faecal incontinence in children with spina bifida. METHODS: We identified a homogenous group of spina bifida patients in whom RCE was initiated (Jan 2006-July 2013). Confidential assessments included (i) Fecal Incontinence Quality Of Life (FIQOL), (ii) St Marks Faecal Incontinence score, (iii) Cleveland Clinic Constipation score and (iv) Neurogenic Bowel Dysfunction score...
November 10, 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27862078/current-controversies-in-prenatal-diagnosis-1-in-utero-therapy-for-spina-bifida-is-ready-for-endoscopic-repair
#10
Michael Belfort, Jan Deprest, Kurt Hecher
No abstract text is available yet for this article.
November 18, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27857789/epidemiology-of-the-neural-tube-defects-in-kashmir-valley
#11
Masood Ahmed Laharwal, Arif Hussain Sarmast, Altaf Umer Ramzan, Abrar Ahad Wani, Nayil Khursheed Malik, Sajad Hussain Arif, Masooma Rizvi
INTRODUCTION/BACKGROUND: Neural tube defects (NTD) are the most common congenital malformations affecting the brain and spinal cord and have a multifactorial etiology. Genetic and environmental factors have been found to cause these defects, both individually and in combination. AIMS AND OBJECTIVES: The aim of this study was to determine the incidence, types, demographics, risk factors, and other associated anomalies relevant to NTDs in Kashmir Valley. MATERIALS AND METHODS: A 2-year hospital-based prospective study was carried out from November 2013 to October 2015...
July 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/27831479/testing-the-utility-of-a-bio-neuropsychosocial-model-for-predicting-medical-adherence-and-responsibility-during-early-adolescence-in-youth-with-spina-bifida
#12
Alexandra M Psihogios, Caitlin Murray, Kathy Zebracki, Laura Acevedo, Grayson N Holmbeck
OBJECTIVES : The present longitudinal, multi-method, and multi-informant study examined biological, neuropsychological, and social predictors of medical adherence and responsibility among early adolescents with spina bifida (SB). METHODS : Youth with SB (M age = 11.40 at Time 1) and their parents and teachers completed surveys, and families and peers completed observational assessments, at two biennial data collection time points (n = 112 for both time points). Multinomial logistic regressions tested predictors of group membership (adherent vs...
November 9, 2016: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/27822764/hemimetameric-shift-in-spina-bifida-three-case-reports
#13
Huseyin Canaz, Gokhan Canaz, Bekir Yavuz Ucar, Ibrahim Alatas
PURPOSE: Hemivertebrae is the most frequent reason of congenital scoliosis, and hemimetameric shift is a finding, which is characterized by two hemivertebraes located contralateral, with at least one normal vertebra between them. Embryologically, hemivertebrae is caused by delay in somite movements and as a result, a total vertebral shift occurs because of mismatches in the following segments. Hemimetameric shift accompanying spina bifida is described as extremely rare. There are only two case series of hemimetameric shift in literature but no spina bifida patient was reported in these series...
November 7, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27804246/polymyxin-b-immobilized-column-direct-hemoperfusion-for-adolescent-toxic-shock-syndrome
#14
Etsuro Nanishi, Yuichirou Hirata, Sooyoung Lee, Noriyuki Kaku, Kenta Momii, Kensuke Kubota, Hisanori Nishio, Yoshihiko Maehara, Toshiro Hara
Toxic shock syndrome (TSS) is a critical illness associated with toxin from Staphylococcus aureus. Despite recent advances in critical care, mortality remains high and additional effective therapy is required. We report an adolescent case of TSS successfully treated with direct hemoperfusion using polymyxin-B immobilized fiber (PMX-DHP). The patient with spina bifida also had ischial pressure ulcer, and developed TSS associated with methicillin-resistant S. aureus. Despite conventional treatment, the patient developed refractory shock, which was immediately improved with PMX-DHP...
October 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27800063/a-proposed-solution-to-a-urological-tightrope-walk-the-challenge-of-transition-of-spina-bifida-patients-from-pediatric-to-adult-care-in-ontario
#15
REVIEW
Martin A Koyle, Nicole Golda, Christopher Hillis, Betty Oldershaw, Margaret DeMelo, Jennifer Uyeno
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27800050/-if-you-build-it%C3%A2-creating-an-adequate-support-system-to-transition-the-care-of-pediatric-patients-with-spina-bifida-into-adulthood
#16
Peter A M Anderson
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27800048/a-proposed-solution-to-a-urological-tightrope-walk-the-challenge-of-transition-of-spina-bifida-patients-from-pediatric-to-adult-care-in-ontario
#17
REVIEW
Martin A Koyle, Nicole Golda, Christopher Hillis, Betty Oldershaw, Margaret DeMelo, Jennifer Uyeno
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27798984/rate-of-shunt-revision-as-a-function-of-age-in-patients-with-shunted-hydrocephalus-due-to-myelomeningocele
#18
Esther B Dupepe, Betsy Hopson, James M Johnston, Curtis J Rozzelle, W Jerry Oakes, Jeffrey P Blount, Brandon G Rocque
OBJECTIVE It is generally accepted that cerebrospinal fluid shunts fail most frequently in the first years of life. The purpose of this study was to describe the risk of shunt failure for a given patient age in a well-defined cohort with shunted hydrocephalus due to myelomeningocele (MMC). METHODS The authors analyzed data from their institutional spina bifida research database including all patients with MMC and shunted hydrocephalus. For the entire population, the number of shunt revisions in each year of life was determined...
November 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27787650/the-relationship-between-the-level-of-lesion-and-progression-in-reimer-s-index-of-spina-bifida-patients
#19
Huseyin Gunay, Murat Celal Sozbilen, Mahmut Altınisik, Ismail Eralp Kacmaz, Elcil Kaya Bicer
AIM: We aimed to evaluate the influence of the lesion level and acetabular displasia on the progression of hip dislocation in patients with spina bifida. MATERIAL AND METHOD: Two hundred twelve hips of 106 cases with spina bifida were evaluated both clinically and radiologically. Their vertebral level of lesions, clinical examinations, radiological migration index, and acetabulum terms were noted and were evaluated in terms of their relations with the level of lesion-migration and dysplasia...
October 27, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27780281/surgical-management-of-functional-constipation-preliminary-report-of-a-new-approach-using-a-laparoscopic-sigmoid-resection-combined-with-a-malone-appendicostomy
#20
Alessandra Gasior, Giulia Brisighelli, Karen Diefenbach, Victoria Alison Lane, Carlos Reck, Richard J Wood, Marc Levitt
Introduction Functional constipation is a common problem in children. It usually can be managed with laxatives but a small subset of patients develop intolerable cramps and need to be temporarily treated with enemas. The senior author has previously reported: 1) open sigmoid resection as a surgical option, but this did not sufficiently reduce the laxative need, then 2) a transanal approach (with resection of rectosigmoid), but this led to a high rate of soiling due to extensive stretching of the anal canal and loss of the rectal reservoir...
October 25, 2016: European Journal of Pediatric Surgery
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