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https://www.readbyqxmd.com/read/28214906/-evaluating-the-quality-of-care-in-nursing-homes-comparison-of-three-international-models
#1
Alessandro Rubino, Fabrizio Leigheb, Carmela Rinaldi, Angelo Di Dio, Sanita Knesse, Chiara Donnarumma, Massimiliano Panella
The aim of this observational descriptive study was to identify the main international models evaluating the quality of nursing homes for non self-sufficient elderly persons, and to apply them in the Italian health system. Firstly, a bibliographic search of institutional websites and Pubmed-Medline was performed to identify the main international models. Secondly, three variables were chosen to evaluate the level of implementability of the models: (1) frequency of use of quality indicators in the international models; (2) degree of constructability of the models in two Italian nursing homes; (3) perceived relevance of the indicators used by the chosen models, by nursing home workers...
November 2016: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28214772/i-could-have-done-otherwise-availability-of-counterfactual-comparisons-informs-the-sense-of-agency
#2
Eugenia Kulakova, Nima Khalighinejad, Patrick Haggard
Personal control and agency are closely associated with the counterfactual notion that a person could have done otherwise (CDO). In both philosophy and law, this counterfactual evaluation determines responsibility and punishment, yet little is known about its influence on agents' experience during action. We used a risky decision-making task to study how counterfactual evaluations influenced participants' sense of agency. Two factors were manipulated independently: the presence/absence of counterfactual comparisons between actions and the presence/absence of counterfactual comparisons between outcomes of these actions...
February 16, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28213842/determination-of-the-porosity-of-plga-microparticles-by-tracking-their-sedimentation-velocity-using-a-flow-imaging-microscope-flowcam
#3
A S Sediq, S K D Waasdorp, M R Nejadnik, M M C van Beers, J Meulenaar, R Verrijk, W Jiskoot
PURPOSE: To investigate whether particle sedimentation velocity tracking using a flow imaging microscope (FlowCAM) can be used to determine microparticle porosity. METHODS: Two different methods were explored. In the first method the sedimentation rate of microparticles was tracked in suspending media with different densities. The porosity was calculated from the average apparent density of the particles derived by inter- or extrapolation to the density of a suspending medium in which the sedimentation velocity was zero...
February 17, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28213396/fear-by-association-perceptions-of-anti-immigrant-policy-and-health-outcomes
#4
Edward D Vargas, Gabriel R Sanchez, Melina Juárez
The United States is experiencing a renewed period of immigration and immigrant policy activity as well as heightened enforcement of such policies. This intensified activity can affect various aspects of immigrant health, including mental health. We use the Robert Wood Johnson Foundation 2015 Latino National Health and Immigration Survey (n = 1,493) to examine the relationship between immigration and immigrant policy and Latino health and well-being. We estimate a series of categorical regression models and find that there are negative health consequences associated with Latinos' perceptions of living in states with unfavorable anti-immigration laws, including reporting poor health and problems with mental health...
February 17, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28213010/the-pathogenesis-and-pathophysiology-of-gestational-diabetes-mellitus-deductions-from-a-three-part-longitudinal-metabolomics-study-in-china
#5
REVIEW
Kai P Law, Hua Zhang
Gestational diabetes mellitus (GDM) is a form of diabetes that is first recognised during pregnancy, with no evidence of pre-existing type 1 or type 2 diabetes. The prevalence of GDM has been rising steadily over the past few decades, coinciding with the ongoing epidemic of obesity and type 2 diabetes. Although GDM normally disappears after delivery, women who have been previously diagnosed with GDM are at a greater risk of developing gestational diabetes in subsequent pregnancies, and type 2 diabetes later in life...
February 14, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28212440/emergent-inequality-and-self-organized-social-classes-in-a-network-of-power-and-frustration
#6
Benoit Mahault, Avadh Saxena, Cristiano Nisoli
We propose a simple agent-based model on a network to conceptualize the allocation of limited wealth among more abundant expectations at the interplay of power, frustration, and initiative. Concepts imported from the statistical physics of frustrated systems in and out of equilibrium allow us to compare subjective measures of frustration and satisfaction to collective measures of fairness in wealth distribution, such as the Lorenz curve and the Gini index. We find that a completely libertarian, law-of-the-jungle setting, where every agent can acquire wealth from or lose wealth to anybody else invariably leads to a complete polarization of the distribution of wealth vs...
2017: PloS One
https://www.readbyqxmd.com/read/28212401/preload-based-starling-like-control-of-rotary-blood-pumps-an-in-vitro-evaluation
#7
Mahdi Mansouri, Shaun D Gregory, Robert F Salamonsen, Nigel H Lovell, Michael C Stevens, Jo P Pauls, Rini Akmeliawati, Einly Lim
Due to a shortage of donor hearts, rotary left ventricular assist devices (LVADs) are used to provide mechanical circulatory support. To address the preload insensitivity of the constant speed controller (CSC) used in conventional LVADs, we developed a preload-based Starling-like controller (SLC). The SLC emulates the Starling law of the heart to maintain mean pump flow ([Formula: see text]) with respect to mean left ventricular end diastolic pressure (PLVEDm) as the feedback signal. The SLC and CSC were compared using a mock circulation loop to assess their capacity to increase cardiac output during mild exercise while avoiding ventricular suction (marked by a negative PLVEDm) and maintaining circulatory stability during blood loss and severe reductions in left ventricular contractility (LVC)...
2017: PloS One
https://www.readbyqxmd.com/read/28212329/enzyme-assisted-discovery-of-antioxidant-peptides-from-edible-marine-invertebrates-a-review
#8
REVIEW
Tsun-Thai Chai, Yew-Chye Law, Fai-Chu Wong, Se-Kwon Kim
Marine invertebrates, such as oysters, mussels, clams, scallop, jellyfishes, squids, prawns, sea cucumbers and sea squirts, are consumed as foods. These edible marine invertebrates are sources of potent bioactive peptides. The last two decades have seen a surge of interest in the discovery of antioxidant peptides from edible marine invertebrates. Enzymatic hydrolysis is an efficient strategy commonly used for releasing antioxidant peptides from food proteins. A growing number of antioxidant peptide sequences have been identified from the enzymatic hydrolysates of edible marine invertebrates...
February 16, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28212204/1-2-4-dibromophenyl-3-6-6-trimethyl-1-5-6-7-tetrahydro-4h-indazol-4-one-a-novel-opioid-receptor-agonist-with-less-accompanying-gastrointestinal-dysfunction-than-morphine
#9
Po-Kuan Chao, Shau-Hua Ueng, Li-Chin Ou, Teng-Kuang Yeh, Wan-Ting Chang, Hsiao-Fu Chang, Shu-Chun Chen, Pao-Luh Tao, Ping-Yee Law, Horace H Loh, Ming-Fu Cheng, Jian-Ying Chuang, Chiung-Tong Chen, Chuan Shih, Shiu-Hwa Yeh
BACKGROUND: The authors investigated the pharmacology and signaling pathways of the opioid receptors modulated by compound 1, 1-(2,4-dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one. METHODS: In vitro studies of compound 1 were assessed by using a radioligand-binding assay (n = 3), a cyclic adenosine monophosphate assay (n = 3), a β-arrestin assay (n = 3), an internalization assay (n = 3), and an immunohistochemistry (n = 8). In vivo studies of compound 1 were characterized using a tail-flick test (n = 5 to 6), tail-clip test (n = 7), von Frey hair test (n = 5), and charcoal meal test (n = 5)...
February 17, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28212167/the-varying-roles-of-nurses-during-interfacility-care-transitions
#10
Lianne Jeffs, Marianne Saragosa, Madelyn Law, Kerry Kuluski, Sherry Espin, Heidi Parker, Kristen Collins
This study explored health care professionals' perceptions and experiences associated with the role of point-of-care nurses during care transitions from an acute care hospital to a rehabilitation setting to being discharged home. We used a qualitative exploratory design and semistructured interviews. Content analysis revealed 3 themes that point to the ambiguity related to the roles that nurses enact with older patients during care transitions. We suggest ways to better support nurses to engage in quality care transitions...
February 15, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/28212112/cancer-as-robust-intrinsic-state-shaped-by-evolution-a-key-issues-review
#11
Ruoshi Yuan, Xiaomei Zhu, Gaowei Wang, Site Li, Ping Ao
Cancer is a complex disease: its pathology cannot be properly understood in terms of independent players-genes, proteins, molecular pathways, or their simple combinations. This is similar to many-body physics of a condensed phase that many important properties are not determined by a single atom or molecule. The rapidly accumulating large 'omics' data also require a new mechanistic and global underpinning to organize for rationalizing cancer complexity. A unifying and quantitative theory was proposed by some of the present authors that cancer is a robust state formed by the endogenous molecular-cellular network, which is evolutionarily built for the developmental processes and physiological functions...
February 17, 2017: Reports on Progress in Physics
https://www.readbyqxmd.com/read/28211994/building-the-coverage-continuum-the-role-of-state-medicaid-directors-and-insurance-commissioners
#12
Joel Ario, Deborah Bachrach
Issue: The Affordable Care Act has expanded coverage to 20 million newly insured individuals, split between state Medicaid programs and commercially insured marketplaces, with limited integration between the two. The seamless continuum of coverage envisioned by the law is central to achieving the full potential of the Affordable Care Act, but it remains an elusive promise. Goals: To examine the historical and cultural differences between state Medicaid agencies and insurance departments that contribute to this lack of coordination...
2017: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/28211963/a-parametric-model-of-the-brain-vascular-system-for-estimation-of-the-arterial-input-function-aif-at-the-tissue-level
#13
Siamak P Nejad-Davarani, Hassan Bagher-Ebadian, James R Ewing, Douglas C Noll, Tom Mikkelsen, Michael Chopp, Quan Jiang
In this paper, we introduce a novel model of the brain vascular system, which is developed based on laws of fluid dynamics and vascular morphology. This model is used to address dispersion and delay of the arterial input function (AIF) at different levels of the vascular structure and to estimate the local AIF in DCE images. We developed a method based on the simplex algorithm and Akaike information criterion to estimate the likelihood of the contrast agent concentration signal sampled in DCE images belonging to different layers of the vascular tree or being a combination of different signal levels from different nodes of this structure...
February 17, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28211730/kinetic-turbulence-in-relativistic-plasma-from-thermal-bath-to-nonthermal-continuum
#14
Vladimir Zhdankin, Gregory R Werner, Dmitri A Uzdensky, Mitchell C Begelman
We present results from particle-in-cell simulations of driven turbulence in magnetized, collisionless, and relativistic pair plasmas. We find that the fluctuations are consistent with the classical k_{⊥}^{-5/3} magnetic energy spectrum at fluid scales and a steeper k_{⊥}^{-4} spectrum at sub-Larmor scales, where k_{⊥} is the wave vector perpendicular to the mean field. We demonstrate the development of a nonthermal, power-law particle energy distribution f(E)∼E^{-α}, with an index α that decreases with increasing magnetization and increases with an increasing system size (relative to the characteristic Larmor radius)...
February 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28211704/observation-of-classical-quantum-crossover-of-1-f-flux-noise-and-its-paramagnetic-temperature-dependence
#15
C M Quintana, Yu Chen, D Sank, A G Petukhov, T C White, Dvir Kafri, B Chiaro, A Megrant, R Barends, B Campbell, Z Chen, A Dunsworth, A G Fowler, R Graff, E Jeffrey, J Kelly, E Lucero, J Y Mutus, M Neeley, C Neill, P J J O'Malley, P Roushan, A Shabani, V N Smelyanskiy, A Vainsencher, J Wenner, H Neven, John M Martinis
By analyzing the dissipative dynamics of a tunable gap flux qubit, we extract both sides of its two-sided environmental flux noise spectral density over a range of frequencies around 2k_{B}T/h≈1  GHz, allowing for the observation of a classical-quantum crossover. Below the crossover point, the symmetric noise component follows a 1/f power law that matches the magnitude of the 1/f noise near 1 Hz. The antisymmetric component displays a 1/T dependence below 100 mK, providing dynamical evidence for a paramagnetic environment...
February 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28211322/incubation-of-solid-state-c60-fullerene-under-uv-irradiation-mimicking-environmentally-relevant-conditions
#16
Andrea Carboni, Rick Helmus, John R Parsons, Karsten Kalbitz, Pim de Voogt
Carbon-based nanomaterials, such as C60 fullerenes, are expected to accumulate in soil due to direct release and deposition from the atmosphere. However, little is known about the environmental fate of these nanoparticles which may be susceptible to photochemical and microbial degradation. In the present work, C60 was incubated for a period of 28 days and irradiated with UVA light. Three experiments were carried out where the fullerenes were either spiked onto a glass surface or added to quartz sand or sandy soil samples...
February 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28211177/visual-impairment-in-older-institutionalised-canadian-seniors-with-dementia
#17
Estefania Chriqui, Caroline Law, Marie-Jeanne Kergoat, Bernard-Simon Leclerc, Hélène Kergoat
PURPOSE: To estimate the prevalence of visual impairment (VI) in a sub-population of Canadian long-term care facilities, i.e. residents affected by dementia. METHODS: This study was conducted in the long-term care facility units at the Institut universitaire de gériatrie de Montréal. All residents ≥65 years old (y.o.), having a clinical diagnosis of dementia, and able to understand French or English, were eligible for participation in the study. All residents participating in the study received a complete eye exam by an experienced optometrist...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28210984/effect-of-solution-ionic-strength-on-the-pka-of-the-nitroxide-ph-epr-probe-2-2-3-4-5-5-hexamethylimidazolidin-1-oxyl
#18
Kaleigh Margita, Maxim A Voinov, Alex I Smirnov
Spin probe and spin labeling Electron Paramagnetic Resonance methods are indispensable research tools for solving a wide range of bioanalytical problems-from measuring microviscosity and polarity of phase-separated liquids to oxygen concentrations in tissues. One of the emerging uses of spin probes are the studies of proton transfer-related and surface electrostatic phenomena. The latter Electron Paramagnetic Resonance methods rely on molecular probes containing an additional functionality capable of reversible ionization (protonation, in particular) in the immediate proximity to an Electron Paramagnetic Resonance-active reporter group, such as (N-O(•)) for nitroxides...
February 17, 2017: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28210541/a-t1-and-dti-fused-3d-corpus-callosum-analysis-in-mci-subjects-with-high-and-low-cardiovascular-risk-profile
#19
Yi Lao, Binh Nguyen, Sinchai Tsao, Niharika Gajawelli, Meng Law, Helena Chui, Michael Weiner, Yalin Wang, Natasha Leporé
Understanding the extent to which vascular disease and its risk factors are associated with prodromal dementia, notably Alzheimer's disease (AD), may enhance predictive accuracy as well as guide early interventions. One promising avenue to determine this relationship consists of looking for reliable and sensitive in-vivo imaging methods capable of characterizing the subtle brain alterations before the clinical manifestations. However, little is known from the imaging perspective about how risk factors such as vascular disease influence AD progression...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28209640/quantized-thermal-transport-in-single-atom-junctions
#20
Longji Cui, Wonho Jeong, Sunghoon Hur, Manuel Matt, Jan C Klöckner, Fabian Pauly, Peter Nielaba, Juan Carlos Cuevas, Edgar Meyhofer, Pramod Reddy
Thermal transport in individual atomic junctions and chains is of great fundamental interest due to unique quantum effects expected to arise in them. Here, by employing novel, custom-fabricated, picowatt-resolution calorimetric scanning probes, we measure the thermal conductance of gold and platinum metallic wires down to single-atom junctions. Our work reveals that the thermal conductance of gold single atom junctions is quantized at room temperature and shows that the Wiedemann-Franz law relating thermal and electrical conductance is satisfied even in single-atom contacts...
February 16, 2017: Science
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