keyword
MENU ▼
Read by QxMD icon Read
search

lengthening

keyword
https://www.readbyqxmd.com/read/29228043/novel-systems-for-the-application-of-isolated-tensile-compressive-and-shearing-stimulation-of-distraction-callus-tissue
#1
Nicholaus Meyers, Julian Schülke, Anita Ignatius, Lutz Claes
BACKGROUND: Distraction osteogenesis is a procedure widely used for the correction of large bone defects. However, a high complication rate persists, likely due to insufficient stability during maturation. Numerical fracture healing models predict bone regeneration under different mechanical conditions allowing fixation stiffness optimization. However, most models apply a linear elastic material law inappropriate for the transient stresses/strains present during limb lengthening or segment transport...
2017: PloS One
https://www.readbyqxmd.com/read/29227963/the-development-of-a-specific-pathogen-free-spf-barrier-colony-of-marmosets-callithrix-jacchus-for-aging-research
#2
Corinna N Ross, Steven Austad, Kathy Brasky, Celeste J Brown, Larry J Forney, Jonathan A Gelfond, Robert Lanford, Arlan Richardson, Suzette D Tardif
A specific pathogen free (SPF) barrier colony of breeding marmosets (Callithrix jacchus) was established at the Barshop Institute for Longevity and Aging Studies. Rodent and other animal models maintained as SPF barrier colonies have demonstrated improved health and lengthened lifespans enhancing the quality and repeatability of aging research. The marmosets were screened for two viruses and several bacterial pathogens prior to establishing the new SPF colony. Twelve founding animals successfully established a breeding colony with increased reproductive success, improved health parameters, and increased median lifespan when compared to a conventionally housed, open colony...
December 7, 2017: Aging
https://www.readbyqxmd.com/read/29227248/salt-inducible-kinase-3-regulates-the-mammalian-circadian-clock-by-destabilizing-per2-protein
#3
Naoto Hayasaka, Arisa Hirano, Yuka Miyoshi, Isao T Tokuda, Hikari Yoshitane, Junichiro Matsuda, Yoshitaka Fukada
Salt-inducible kinase 3 (SIK3) plays a crucial role in various aspects of metabolism. In the course of investigating metabolic defects in Sik3-deficient mice (Sik3-/-), we observed that circadian rhythmicity of the metabolisms was phase-delayed. Sik3-/- mice also exhibited other circadian abnormalities, including lengthening of the period, impaired entrainment to the light-dark cycle, phase variation in locomotor activities, and aberrant physiological rhythms. Ex vivosuprachiasmatic nucleus slices from Sik3-/- mice exhibited destabilized and desynchronized molecular rhythms among individual neurons...
December 11, 2017: ELife
https://www.readbyqxmd.com/read/29225576/vitamin-d-enhances-efficacy-of-oral-nifedipine-in-treating-preeclampsia-with-severe-features-a-double-blinded-placebo-controlled-and-randomized-clinical-trial
#4
Dan-Dan Shi, Yong Wang, Jun-Jun Guo, Ling Zhou, Na Wang
Vitamin D (VD) has exhibited immunomodulatory role in the pathogenesis of preeclampsia. We hypothesize VD potentiate nifedipine treatment for preeclampsia by shortened the time to control blood pressure and prolong time before subsequent hypertensive crisis. We conduct a randomized trial of 683 primigravid women with preeclampsia, who were assigned to different treatment groups, either nifedipine+placebo or nifedipine+VD orally, by random after screening. Primary endpoints include time to control hypertension and time before another hypertensive crisis...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29223628/five-and-10-year-follow-up-of-nonvascularized-toe-phalanx-transfers
#5
Hidehiko Kawabata, Daisuke Tamura
PURPOSE: The purpose of this study was to evaluate long-term outcomes of nonvascularized toe phalanx transfer. METHODS: We retrospectively reviewed 54 nonvascularized toe phalanx transfers in 29 children with symbrachydactyly. Forty-seven transfers in 24 children were evaluated at 5-year follow-up and 27 transfers in 14 children were evaluated at 10-year follow-up. We recorded the incidence of the early physeal closure and the length of the transferred toe phalanx on plain radiographs at 5- and 10-year follow-up...
December 6, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29223017/biceps-femoris-fascicle-length-during-passive-stretching
#6
Eleftherios Kellis
The purpose of this study was to quantify the relative changes in fascicle (FL) and muscle-tendon unit (LMTU) length of the long head of the biceps femoris (BFlh) at different combinations of hip and knee joint positions. Fourteen participants performed passive knee extension trials from 0°, 45° and 90° of hip flexion. FL, LMTU, pennation angle (PA) and effective FL (FL multiplied by the cosine of the PA) of the BFlh were quantified using ultrasonography (US). Three-way analysis of variance designs indicated that at each hip angle, FL and LMTU increased and PA decreased from 90° to 0° of knee flexion...
December 5, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29220207/mr-imaging-of-muscle-trauma-anatomy-biomechanics-pathophysiology-and-imaging-appearance
#7
Dyan V Flores, Catalina Mejía Gómez, Mauricio Estrada-Castrillón, Edward Smitaman, Mini N Pathria
Muscle is an important component of the muscle-tendon-bone unit, driving skeletal motion through contractions that alter the length of the muscle. The muscle and myotendinous junction (MTJ) are most commonly injured in the young adult, as a result of indirect mechanisms such as overuse or stretching, direct impact (penetrating or nonpenetrating), or dysfunction of the supporting connective tissues. Magnetic resonance (MR) imaging is widely used for assessment of muscle injuries. This review illustrates the MR imaging appearance of a broad spectrum of acute, subacute, and chronic traumatic lesions of muscle, highlighting the pathophysiology, biomechanics, and anatomic considerations underlying these lesions...
December 8, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29219510/spin-fluctuations-in-the-0-7-anomaly-in-quantum-point-contacts
#8
Dennis H Schimmel, Benedikt Bruognolo, Jan von Delft
It has been argued that the 0.7 anomaly in quantum point contacts (QPCs) is due to an enhanced density of states at the top of the QPC barrier (the van Hove ridge), which strongly enhances the effects of interactions. Here, we analyze their effect on dynamical quantities. We find that they pin the van Hove ridge to the chemical potential when the QPC is subopen, cause a temperature dependence for the linear conductance that qualitatively agrees with experiments, strongly enhance the magnitude of the dynamical spin susceptibility, and significantly lengthen the QPC traversal time...
November 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29214392/modulation-of-specific-inhibitory-networks-in-fatigued-locomotor-muscles-of-healthy-males
#9
Stuart Goodall, Glyn Howatson, Kevin Thomas
Reduced maximal force capability of skeletal muscle, as a consequence of exercise, can be due to peripheral or central fatigue mechanisms. In upper-limb muscles, neuromuscular fatigue is concurrent with reduced corticospinal excitability and increased inhibition (lengthened corticospinal silent period [CSP]; reduced short-interval intracortical inhibition [SICI] ratio). However, it is unclear whether these adjustments occur in response to fatiguing exercise of locomotor muscles. This study examined the effect of fatiguing, maximal, knee-extensor exercise on motor cortical excitability and inhibition...
December 6, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29212690/quantifying-the-law-of-diminishing-returns-in-magnetically-controlled-growing-rods
#10
A Ahmad, T Subramanian, P Panteliadis, J Wilson-Macdonald, D A Rothenfluh, C Nnadi
AIMS: Magnetically controlled growing rods (MCGRs) allow non-invasive correction of the spinal deformity in the treatment of early-onset scoliosis. Conventional growing rod systems (CGRS) need repeated surgical distractions: these are associated with the effect of the 'law of diminishing returns'. The primary aim of this study was to quantify this effect in MCGRs over sequential distractions. PATIENTS AND METHODS: A total of 35 patients with a maximum follow-up of 57 months were included in the study...
December 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29212492/using-patient-data-to-optimize-an-expert-based-guideline-on-convalescence-recommendations-after-gynecological-surgery-a-prospective-cohort-study
#11
Esther V A Bouwsma, Johannes R Anema, A Vonk Noordegraaf, Henrica C W de Vet, Judith A F Huirne
BACKGROUND: Convalescence advice is often based on tradition and anecdote from health care providers, rather than being based on experiences from patients themselves. The aim of this study was to analyse recovery in terms of resumption of various daily activities including work, following different laparoscopic and abdominal surgery in order to optimize an expert-based guideline on convalescence recommendations. METHODS: This is a prospective cohort study conducted in nine general and one university hospital in the Netherlands...
December 6, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29210159/safety-of-mtor-inhibitor-continuation-in-pediatric-heart-transplant-recipients-undergoing-surgical-procedures
#12
Ann Heble, Melanie D Everitt, Jane Gralla, Shelley D Miyamoto, Michael Lahart, Jennifer Eshelman
mTOR inhibitors have been associated with SWC when used in the perioperative period. Limited literature is available to guide providers in managing chronic mTOR inhibitor use in the perioperative period, especially in the pediatric setting. The primary aim of this study was to describe the prevalence of SWC with mTOR inhibitor continuation during the perioperative period for major surgeries. Heart transplant recipients ≤25 years old at the time of primary heart transplant receiving sirolimus maintenance therapy during a surgical procedure and within the study period were included...
December 6, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29209982/adherence-to-inhaled-medications-and-its-effect-on-healthcare-utilization-and-costs-among-high-grade-chronic-obstructive-pulmonary-disease-patients
#13
Jee-Ae Kim, Min Kyoung Lim, Kunil Kim, JuHee Park, Chin Kook Rhee
BACKGROUND: Adherence to inhaled medication regimens affects chronic obstructive pulmonary disease (COPD) prognosis and quality of life, and reduces the use of healthcare services, resulting in cost savings. OBJECTIVES: To examine the effects of adherence to inhaled medication regimens on healthcare utilization and costs in high-grade COPD patients. METHODS: We performed an observational retrospective cohort study using a longitudinal data set from the Korean Health Insurance Review and Assessment Service (2008-2013) containing healthcare services' information for 50 million beneficiaries...
December 5, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/29209417/do-athletes-alter-their-running-mechanics-after-an-achilles-tendon-rupture
#14
Daniel Jandacka, Julia Freedman Silvernail, Jaroslav Uchytil, David Zahradnik, Roman Farana, Joseph Hamill
Background: Over the past thirty years, there has been dramatic increase in incidence of Achilles tendon rupture in the athletic population. The purpose of this study was to compare the lower extremity mechanics of Achilles tendon ruptured runners with healthy controls. Methods: The participants with a past history of an Achilles tendon repair (n = 11) and healthy control (n = 11) subgroups were matched on sex, age, type of regular physical activity, mass, height, footfall pattern and lateral dominancy...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29208419/planning-of-polish-physician-workforce-systemic-inconsistencies-challenges-and-possible-ways-forward
#15
Alicja Domagała, Jacek Klich
BACKGROUND: Poland has the lowest number of physicians per 1000 population (2.2/1000) in the EU. This is accompanied by a considerable migration rate of Polish physicians to other EU countries (estimated at above 7%). Among other consequences, this results in waiting lists and unmet health needs. OBJECTIVE: The aim of this article is an identification of the main challenges for physician workforce planning in Poland. METHODS: The authors analysed national and international documents, reports, official statements, publications and statistical databases...
December 1, 2017: Health Policy
https://www.readbyqxmd.com/read/29208195/-treatment-principles-in-bone-reconstruction-and-limb-lengthening-of-the-lower-extremity
#16
Ulrik Kæhler Olesen, Tobias Nygaard, Søren V Kold, Adam Hede
Limb length discrepancies, axis deviations and bone loss on a congenital, traumatic or infectious basis are treated with restoration of axis and bone elongation. The intention is to improve gait and function, to relieve pain caused by imbalance in the musculoskeletal system and to prevent degenerative joint disease. Modern motorized intramedullary nails spare the patients for external fixators, and thus complications are being reduced. X-ray, CT-based planning and a thorough clinical examination is essential for a good result...
November 20, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29207688/radiological-biometric-study-of-metatarsals-and-phalanges
#17
Shrish Patil, G H Hanumantharaya, Suresh P Desai, Madhumati Nidoni
Introduction: Several diseases affect the forefoot bones. Relative dimensions of the forefoot bones are important considerations for preoperative and postoperative assessment of surgeries. The choice of a particular surgery over another can also be made if the surgeon knows the length to which a bone needs to be lengthened or shortened in comparison to other bones of the forefoot. Aim: To measure the dimensions of the metatarsals and phalanges on standardized radiographs and to determine possible correlations amongst them...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29205220/influence-of-modified-muscle-morphology-and-activity-pattern-on-the-results-of-musculoskeletal-system-modelling-in-cerebral-palsy-patient
#18
Justyna Ogrodnik, Szczepan Piszczatowski
PURPOSE: The aim of the present study was to evaluate the influence of modified morphological parameters of the muscle model and excitation pattern on the results of musculoskeletal system numerical simulation in a cerebral palsy patient. METHODS: The modelling of the musculoskeletal system was performed in the AnyBody Modelling System. The standard model (MoCap) was subjected to modifications consisting of changes in morphological parameters and excitation patterns of selected muscles...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29204225/-in-vivo-gastrocnemius-muscle-tendon-ratio-in-patients-with-cerebral-palsy
#19
Muhammad Naghman Choudhry, Haris Naseem, Ihsan Mahmood, Adeel Aqil, Tahir Khan
Background: The position of the gastrocnemius tendon in relation to the leg length may be different in children with cerebral palsy as compared to normal children. The palpation of muscle bellies or previous experience of the operating surgeon is employed to place the surgical incision for lengthening of the gastrocnemius aponeurosis. Inaccurate localisation may cause incorrect incisions and a risk of iatrogenic damage to the vital structures (i.e. sural nerve). Objectives: The aim of our study is to compare gastrocnemius length in-vivo between paretic and unaffected children and create a formula to localise the muscle-tendon junction accurately...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29202984/screwless-scarf-osteotomy-for-hallux-valgus-evaluation-of-radiologic-correction
#20
Dries Van Doninck, Thomas Verschueren, Giovanni A Matricali, Nick Van Opstal, Lennart Scheys, Geoffroy Vandeputte
BACKGROUND: The scarf osteotomy is a standard procedure to correct hallux valgus. Recent modifications in the technique allow for important translations of the bone fragments without the need for screw fixation. We performed the first prospective analysis of radiographic parameters after a screwless scarf osteotomy. Prospective study of pre- and postoperative standing radiographs of the feet let us quantify angle reduction and shortening, lengthening or lowering of the first metatarsal...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
keyword
keyword
46769
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"