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https://www.readbyqxmd.com/read/27755057/programmed-intermittent-epidural-bolus-for-labor-analgesia-during-first-stage-of-labor-a-biased-coin-up-and-down-sequential-allocation-trial-to-determine-the-optimum-interval-time-between-boluses-of-a-fixed-volume-of-10-ml-of-bupivacaine-0-0625-with-fentanyl
#1
Marcelo Epsztein Kanczuk, Nicholas Martin Barrett, Cristian Arzola, Kristi Downey, Xiang Y Ye, Jose C A Carvalho
BACKGROUND: Most studies that have compared programmed intermittent epidural bolus (PIEB) with continuous epidural infusion regimens have included patient-controlled epidural analgesia and/or manual bolus as rescue analgesia for breakthrough pain. Consequently, the optimal time interval between PIEB is yet to be determined. We designed a study to establish the optimal time interval between PIEB of 10 mL of bupivacaine 0.0625% with fentanyl 2 μg/mL to produce effective analgesia in 90% of women during first stage of labor without breakthrough pain...
October 11, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27591455/a-prospective-randomized-blinded-endpoint-controlled-study-continuous-epidural-infusion-versus-programmed-intermittent-epidural-bolus-in-labor-analgesia
#2
Joana Nunes, Sara Nunes, Mariano Veiga, Mara Cortez, Isabel Seifert
BACKGROUND: There is evidence that administration of a programmed intermittent epidural bolus (PIEB) compared to continuous epidural infusion (CEI) leads to greater analgesia efficacy and maternal satisfaction with decreased anesthetic interventions. METHODS: In this study, 166 women with viable pregnancies were included. After an epidural loading dose of 10mL with Ropivacaine 0.16% plus Sufentanil 10μg, parturient were randomly assigned to one of three regimens: A - Ropivacaine 0...
September 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27464978/implementation-of-programmed-intermittent-epidural-bolus-for-the-maintenance-of-labor-analgesia
#3
Brendan Carvalho, Ronald B George, Benjamin Cobb, Christine McKenzie, Edward T Riley
Programmed intermittent epidural bolus (PIEB) is an exciting new technology that has the potential to improve the maintenance of epidural labor analgesia. PIEB compared with a continuous epidural infusion (CEI) has the potential advantage of greater spread within the epidural space and therefore better sensory blockade. Studies have demonstrated a local anesthetic-sparing effect, fewer instrumental vaginal deliveries, less motor blockade, and improvements in maternal satisfaction with PIEB compared with CEI...
October 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27432527/-a-prospective-randomized-blinded-endpoint-controlled-study-continuous-epidural-infusion-versus-programmed-intermittent-epidural-bolus-in-labor-analgesia
#4
Joana Nunes, Sara Nunes, Mariano Veiga, Mara Cortez, Isabel Seifert
BACKGROUND: There is evidence that administration of a programmed intermittent epidural bolus (PIEB) compared to continuous epidural infusion (CEI) leads to greater analgesia efficacy and maternal satisfaction with decreased anesthetic interventions. METHODS: In this study, 166 women with viable pregnancies were included. After an epidural loading dose of 10mL with Ropivacaine 0.16% plus Sufentanil 10μg, parturient were randomly assigned to one of three regimens: A - Ropivacaine 0...
September 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/27387330/obstetric-analgesia-update-2016
#5
Michael Heesen, Markus Klimek
Neuraxial labor analgesia can be initiated via combined spinal-epidural (CSE) or stand-alone epidural. Pros and cons of these techniques are outlined in this review. In recent years computer-integrated patient-controlled epidural analgesia (CI-PCEA) and programed intermittent epidural boluses (PIEB) have been developed, adding to continuous infusion and PCEA for the maintenance of neuraxial analgesia. Postdural puncture headache (PDPH) and fever can occur secondary to labor epidural that both have clinical relevance for the care givers...
July 7, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27361635/injury-profile-of-time-loss-injuries-in-non-elite-community-u-s-rugby-7s-tournament-players-3066-board-131-june-3-3-30-pm-5-00-pm
#6
Richard Ma, Victor Lopez, Christian Victoria, Meryle G Weinstien, Tony Locrotondo, Jessica F Dellalo, Sarah K Piebes, Answorth A Allen
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27100210/a-retrospective-comparison-of-programmed-intermittent-epidural-bolus-with-continuous-epidural-infusion-for-maintenance-of-labor-analgesia
#7
Michael Tien, Terrence K Allen, Amy Mauritz, Ashraf S Habib
OBJECTIVE: To assess whether maintenance of labor epidural analgesia using programmed intermittent epidural bolus (PIEB) is associated with reduced local anesthetic (LA) consumption, patient-controlled epidural analgesia (PCEA) use, and rescue analgesia requirements compared to continuous epidural infusion (CEI). RESEARCH DESIGN AND METHODS: This is a retrospective study at an academic university medical center. Women receiving epidural labor analgesia from March to July of 2015 were identified and categorized into three groups: 1) CEI 5 mL/hr, 2) PIEB 5 mL/60 minutes, 3) PIEB 3 mL/30 minutes...
August 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/26775896/programmed-intermittent-epidural-boluses-for-maintenance-of-labor-analgesia-an-impact-study
#8
C P McKenzie, B Cobb, E T Riley, B Carvalho
INTRODUCTION: The aim of this impact study was to compare the analgesic efficacy and side effect profile of programmed intermittent epidural boluses (PIEB)+patient-controlled epidural analgesia (PCEA) to continuous epidural infusion (CEI)+PCEA for maintenance labor analgesia after the introduction of PIEB at our institution. METHODS: We conducted a retrospective analysis after replacing the background CEI with PIEB for our labor PCEA. Pre-change pump settings were CEI 12mL/h with PCEA (12mL bolus, lockout 15min); PIEB settings were a 9mL bolus every 45min with PCEA (10mL bolus, lockout 10min)...
May 2016: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/26533907/impact-of-uncertainty-in-predicted-risks-on-the-cost-effectiveness-of-risk-stratified-preventive-treatment-strategies
#9
A van Giessen, M Piebes, H Koffijberg
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/23935992/a-role-for-mecp2-in-switching-gene-activity-via-chromatin-unfolding-and-hp1%C3%AE-displacement
#10
Maartje C Brink, Diewertje G E Piebes, Marloes L de Groote, Martijn S Luijsterburg, Corella S Casas-Delucchi, Roel van Driel, Marianne G Rots, M Cristina Cardoso, Pernette J Verschure
Methyl-CpG-binding protein 2 (MeCP2) is generally considered to act as a transcriptional repressor, whereas recent studies suggest that MeCP2 is also involved in transcription activation. To gain insight into this dual function of MeCP2, we assessed the impact of MeCP2 on higher-order chromatin structure in living cells using mammalian cell systems harbouring a lactose operator and reporter gene-containing chromosomal domain to assess the effect of lactose repressor-tagged MeCP2 (and separate MeCP2 domains) binding in living cells...
2013: PloS One
https://www.readbyqxmd.com/read/21788309/programmed-intermittent-epidural-bolus-versus-continuous-epidural-infusion-for-labor-analgesia-the-effects-on-maternal-motor-function-and-labor-outcome-a-randomized-double-blind-study-in-nulliparous-women
#11
RANDOMIZED CONTROLLED TRIAL
Giorgio Capogna, Michela Camorcia, Silvia Stirparo, Alessio Farcomeni
BACKGROUND: Programmed intermittent epidural anesthetic bolus (PIEB) technique may result in reduced total local anesthetic consumption, fewer manual boluses, and greater patient satisfaction compared with continuous epidural infusion (CEI). In this randomized, double-blind study, we compared the incidence of motor block and labor outcome in women who received PIEB or CEI for maintenance of labor analgesia. The primary outcome variable was maternal motor function and the secondary outcome was mode of delivery...
October 2011: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/21411828/measurement-properties-of-headache-specific-outcomes-scales-in-adolescent-athletes
#12
Sarah K Piebes, Alison R Snyder, R Curtis Bay, Tamara C Valovich McLeod
CONTEXT: Recurrent headaches significantly affect health-related quality of life (HRQOL) in adults; the impact of headache on HRQOL among adolescents is unknown, and the psychometric properties of headache-specific outcomes instruments have not been adequately studied in this population. OBJECTIVE: To evaluate the psychometric properties of the Headache Impact Test (HIT-6) and Pediatric Migraine Disability Assessment (PedMIDAS) in healthy adolescent athletes. DESIGN: Descriptive survey...
February 2011: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/20415021/-code-recommendation-veterinary-products-where-are-the-boundaries
#13
Arend Piebes
No abstract text is available yet for this article.
March 15, 2010: Tijdschrift Voor Diergeneeskunde
https://www.readbyqxmd.com/read/19537510/-subacute-ruminal-acidosis-claw-problems-and-infertility-in-high-producing-milk-cows
#14
REVIEW
A H G Piebes, B van de Griend, M J W Rijnders, I J R de Vries, G C van der Weijden, M A Crowe, E Gruys
No abstract text is available yet for this article.
June 1, 2009: Tijdschrift Voor Diergeneeskunde
https://www.readbyqxmd.com/read/19535497/caring-for-student-athletes-following-a-concussion
#15
REVIEW
Sarah K Piebes, Meganne Gourley, Tamara C Valovich McLeod
The school nurse plays a dynamic role in the care and treatment of a concussed athlete. Concussions in the adolescent populations are of special concern due to their potential impact on mental development and cognitive function, as well as an increased risk of serious complications including second impact syndrome. The complexity of a concussion requires collaboration between of a variety of health care and school personnel to create an optimal situation for the student-athlete and their family. As the primary health care provider for students during the school day, school nurses can help ensure all necessary steps are taken to aid the recovery of an injured student-athlete...
August 2009: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/18666436/nfkappab-activation-and-drug-sensitivity-in-human-neoplastic-cells-treated-with-anthracyclines
#16
Beata M Gruber, Elzbieta L Anuszewska, Irena Bubko, Teresa Kasprzycka-Guttman, Irena Misiewicz, Katarzyna Skupińska, Izabela Fokt, Waldemar Piebe
NFkappaB (nuclear factor kappaB) is a transcription factor controlling, among others, cell proliferation and apoptosis. The potent activators of NFkappaB are anthracyclines which can activate apoptotic processes. As shown by some authors, NFkappaB activated by these drugs well correlated with their cytotoxic activity. The aim of this study was to assess the effects of doxorubicin (DOX) and its analogs (annamycin, WP903) on the NFkappaB activity in human melanoma cells: a sensitive (ME18) and a resistant to DOX (ME18/R) and its possible correlation with cell sensitivity to these drugs...
March 2008: Acta Poloniae Pharmaceutica
https://www.readbyqxmd.com/read/16585584/the-bovine-cd1-family-contains-group-1-cd1-proteins-but-no-functional-cd1d
#17
COMPARATIVE STUDY
Ildiko Van Rhijn, Ad P Koets, Jin Seon Im, Diewertje Piebes, Faye Reddington, Gurdyal S Besra, Steven A Porcelli, Willem van Eden, Victor P M G Rutten
The CD1 family of proteins presents lipid Ags to T cells. Human CD1a, CD1b, and CD1c have been shown in humans to present mycobacterial lipid Ags. Cattle, like humans, are a natural host of several mycobacterial pathogens. In this study, we describe the CD1 family of genes in cattle (Bos taurus) and provide evidence that B. taurus expresses CD1a, CD1e, and multiple CD1b molecules, but no CD1c and CD1d molecules. In mice and humans, CD1d is known to present Ag to NKT cells, a T cell lineage that is characterized by a limited TCR repertoire, capable of rapidly secreting large amounts of IFN-gamma and IL-4...
April 15, 2006: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/16492849/a-randomized-comparison-of-programmed-intermittent-epidural-bolus-with-continuous-epidural-infusion-for-labor-analgesia
#18
RANDOMIZED CONTROLLED TRIAL
Cynthia A Wong, John T Ratliff, John T Sullivan, Barbara M Scavone, Paloma Toledo, Robert J McCarthy
Bolus injection through an epidural catheter may result in better distribution of anesthetic solution in the epidural space compared with continuous infusion of the same anesthetic solution. In this randomized, double-blind study we compared total bupivacaine consumption, need for supplemental epidural analgesia, quality of analgesia, and patient satisfaction in women who received programmed intermittent epidural boluses (PIEB) compared with continuous epidural infusion (CEI) for maintenance of labor analgesia...
March 2006: Anesthesia and Analgesia
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