keyword
https://read.qxmd.com/read/38683997/genetic-and-phenotypic-profiling-of-single-living-circulating-tumor-cells-from-patients-with-microfluidics
#21
JOURNAL ARTICLE
Zaizai Dong, Yusen Wang, Gaolian Xu, Bing Liu, Yang Wang, Julien Reboud, Pawel Jajesniak, Shi Yan, Pingchuan Ma, Feng Liu, Yuhao Zhou, Zhiyuan Jin, Kuan Yang, Zhaocun Huang, Minglei Zhuo, Bo Jia, Jian Fang, Panpan Zhang, Nan Wu, Mingzhu Yang, Jonathan M Cooper, Lingqian Chang
Accurate prediction of the efficacy of immunotherapy for cancer patients through the characterization of both genetic and phenotypic heterogeneity in individual patient cells holds great promise in informing targeted treatments, and ultimately in improving care pathways and clinical outcomes. Here, we describe the nanoplatform for interrogating living cell host-gene and (micro-)environment (NICHE) relationships, that integrates micro- and nanofluidics to enable highly efficient capture of circulating tumor cells (CTCs) from blood samples...
May 7, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38682564/tunable-nanofluidic-device-for-digital-nucleic-acid-analysis
#22
JOURNAL ARTICLE
Imman I Hosseini, Seyed Vahid Hamidi, Xavier Capaldi, Zezhou Liu, Matheus Azevedo Silva Pessoa, Sara Mahshid, Walter Reisner
Nano/microfluidic-based nucleic acid tests have been proposed as a rapid and reliable diagnostic technology. Two key steps for many of these tests are target nucleic acid (NA) immobilization followed by an enzymatic reaction on the captured NAs to detect the presence of a disease-associated sequence. NA capture within a geometrically confined volume is an attractive alternative to NA surface immobilization that eliminates the need for sample pre-treatment ( e.g. label-based methods such as lateral flow assays) or use of external actuators ( e...
April 29, 2024: Nanoscale
https://read.qxmd.com/read/38681725/nanofluidic-logic-with-mechano-ionic-memristive-switches
#23
JOURNAL ARTICLE
Theo Emmerich, Yunfei Teng, Nathan Ronceray, Edoardo Lopriore, Riccardo Chiesa, Andrey Chernev, Vasily Artemov, Massimiliano Di Ventra, Andras Kis, Aleksandra Radenovic
Neuromorphic systems are typically based on nanoscale electronic devices, but nature relies on ions for energy-efficient information processing. Nanofluidic memristive devices could thus potentially be used to construct electrolytic computers that mimic the brain down to its basic principles of operation. Here we report a nanofluidic device that is designed for circuit-scale in-memory processing. The device, which is fabricated using a scalable process, combines single-digit nanometric confinement and large entrance asymmetry and operates on the second timescale with a conductance ratio in the range of 9 to 60...
2024: Nature Electronics
https://read.qxmd.com/read/38678146/entropy-optimization-of-lid-driven-micropolar-hybrid-nanofluid-flow-in-a-partially-porous-hexagonal-shaped-cavity-with-relevance-to-energy-efficient-storage-processes
#24
JOURNAL ARTICLE
Anil Ahlawat, Shilpa Chaudhary, Mukesh Kumar Sharma, K Loganathan, Balachandra Pattanaik, Allam Balaram
Hydromagnetically associated heat convection can greatly enhance the performance of high-efficiency thermal appliances and renewable energy sources through an optimized design. This investigation examines the production of thermodynamic irreversibility and heat convection for a double lid-driven flow within a partially porous stratified hexagonal enclosure. The top and bottom-wall are moving in the opposite direction with an equal velocity U0 . The top-wall and the bottom-wall are kept at temperature Tc and Th (Th   <mml:math xmlns:mml="https://www...
April 27, 2024: Scientific Reports
https://read.qxmd.com/read/38675626/secondary-atomization-and-micro-explosion-effect-induced-by-surfactant-and-nanoparticles-on-enhancing-the-combustion-performance-of-al-jp-10-oa-nanofluid-fuel
#25
JOURNAL ARTICLE
Shengji Li, Zixuan Liu, Qianmei Yang, Zhangtao Wang, Xuefeng Huang, Dan Luo
Aluminum/tetrahydrodicyclopentadiene/oleic acid (Al/JP-10/OA) nanofluid fuel is considered a potential fuel for aircraft powered by aviation turbine engines. However, an optimized formula for an Al/JP-10/OA system inducing a secondary atomization and micro-explosion effect and improving the burning performance needs to be developed. With this aim, in this work, the combustion characteristics of pure JP-10, JP-10/OA, JP-10/Al, and Al/JP-10/OA were experimentally tested, and a comparative analysis was conducted...
April 16, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38675004/copper-quantum-dot-polyacrylamide-composite-nanospheres-spreading-on-quartz-flake-surfaces-and-displacing-crude-oil-in-microchannel-chips
#26
JOURNAL ARTICLE
Xinru Ma, Haien Yang, Xiaofei Liu, Lixiang Zeng, Xinzi Li, Lijun Zheng, Yu Yang, Lei Cao, Weikai Meng, Junping Zheng
Polyacrylamide, silica, and other nanoparticles have all been realized in the field of enhanced oil recovery. Researchers often explore the mechanisms of spreading behavior and simulated displacement to develop more efficient types of nanoparticles. In this study, copper quantum dots were introduced into a acrylamide copolymerization system to obtain composite nanospheres and its structure, topographic, and application performance were characterized. The results show that the composite nanospheres have a particle size of around 25 nm, are uniformly loaded with copper particles, and have good temperature resistance...
April 12, 2024: Polymers
https://read.qxmd.com/read/38669337/accurate-prediction-of-solvent-flux-in-sub-1-nm-slit-pore-nanosheet-membranes
#27
JOURNAL ARTICLE
Xiaofang Chen, Yao Qin, Yudan Zhu, Xueling Pan, Yuqi Wang, Hongyu Ma, Ruoxin Wang, Christopher D Easton, Yu Chen, Cheng Tang, Aijun Du, Aisheng Huang, Zongli Xie, Xiwang Zhang, George P Simon, Mark M Banaszak Holl, Xiaohua Lu, Kostya Novoselov, Huanting Wang
Nanosheet-based membranes have shown enormous potential for energy-efficient molecular transport and separation applications, but designing these membranes for specific separations remains a great challenge due to the lack of good understanding of fluid transport mechanisms in complex nanochannels. We synthesized reduced MXene/graphene hetero-channel membranes with sub-1-nm pores for experimental measurements and theoretical modeling of their structures and fluid transport rates. Our experiments showed that upon complete rejection of salt and organic dyes, these membranes with subnanometer channels exhibit remarkably high solvent fluxes, and their solvent transport behavior is very different from their homo-structured counterparts...
April 26, 2024: Science Advances
https://read.qxmd.com/read/38666542/artificial-funnel-nanochannel-device-emulates-synaptic-behavior
#28
JOURNAL ARTICLE
Peiyue Li, Junjie Liu, Jun-Hui Yuan, Yechang Guo, Shaofeng Wang, Pan Zhang, Wei Wang
Creating artificial synapses that can interact with biological neural systems is critical for developing advanced intelligent systems. However, there are still many difficulties, including device morphology and fluid selection. Based on Micro-Electro-Mechanical System technologies, we utilized two immiscible electrolytes to form a liquid/liquid interface at the tip of a funnel nanochannel, effectively enabling a wafer-level fabrication, interactions between multiple information carriers, and electron-to-chemical signal transitions...
April 26, 2024: Nano Letters
https://read.qxmd.com/read/38665553/dual-solutions-of-magnetized-radiative-flow-of-casson-nanofluid-over-a-stretching-shrinking-cylinder-stability-analysis
#29
JOURNAL ARTICLE
Azhar Mustafa Soomro, Mustafa Abbas Fadhel, Liaquat Ali Lund, Zahir Shah, Mansoor H Alshehri, Narcisa Vrinceanu
The enhanced thermal efficiency exhibited by Casson nanofluids offers significant practical applications across various industrial and engineering sectors. This study focuses on the mathematical investigation of the steady magnetohydrodynamic (MHD) boundary layer flow of Casson nanofluid through a stretched/shrinking cylinder, taking into account the effects of suction and thermal radiation. The governing partial differential equations (PDEs) have been subjected to a similarity transformation, resulting in a set of nonlinear ordinary differential equations (ODEs)...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38657046/brain-inspired-computing-with-fluidic-iontronic-nanochannels
#30
JOURNAL ARTICLE
Tim M Kamsma, Jaehyun Kim, Kyungjun Kim, Willem Q Boon, Cristian Spitoni, Jungyul Park, René van Roij
The brain's remarkable and efficient information processing capability is driving research into brain-inspired (neuromorphic) computing paradigms. Artificial aqueous ion channels are emerging as an exciting platform for neuromorphic computing, representing a departure from conventional solid-state devices by directly mimicking the brain's fluidic ion transport. Supported by a quantitative theoretical model, we present easy-to-fabricate tapered microchannels that embed a conducting network of fluidic nanochannels between a colloidal structure...
April 30, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38656267/detection-and-identification-of-single-ribonucleotide-monophosphates-using-a-dual-in-plane-nanopore-sensor-made-in-a-thermoplastic-via-replication
#31
JOURNAL ARTICLE
Chathurika Rathnayaka, Indu A Chandrosoma, Junseo Choi, Katie Childers, Maximillian Chibuike, Khurshed Akabirov, Farhad Shiri, Adam R Hall, Maxwell Lee, Collin McKinney, Matthew Verber, Sunggook Park, Steven A Soper
We report the generation of ∼8 nm dual in-plane pores fabricated in a thermoplastic via nanoimprint lithography (NIL). These pores were connected in series with nanochannels, one of which served as a flight tube to allow the identification of single molecules based on their molecular-dependent apparent mobilities ( i.e. , dual in-plane nanopore sensor). Two different thermoplastics were investigated including poly(methyl methacrylate), PMMA, and cyclic olefin polymer, COP, as the substrate for the sensor both of which were sealed using a low glass transition cover plate (cyclic olefin co-polymer, COC) that could be thermally fusion bonded to the PMMA or COP substrate at a temperature minimizing nanostructure deformation...
April 24, 2024: Lab on a Chip
https://read.qxmd.com/read/38654016/pulsatile-nanofluid-flow-with-variable-pressure-gradient-and-heat-transfer-in-wavy-channel
#32
JOURNAL ARTICLE
A S Dawood, Faisal A Kroush, Ramzy M Abumandour, Islam M Eldesoky
This research contributes to the comprehension of nanofluid behaviour through a wavy channel, emphasizing the significance of considering diverse influences in the modelling process. The study explores the collective influence of pressure gradient variation, magnetic field, porosity, channel waviness, nanoparticle concentration, and heat transfer on nano-blood flow in a two-dimensional wavy channel. In contrast to prior research assuming a constant pulsatile pressure gradient during channel waviness, this innovative study introduces a variable pressure gradient, significantly influencing several associated parameters...
April 23, 2024: Scientific Reports
https://read.qxmd.com/read/38649440/enhanced-stability-superior-anti-corrosive-and-tribological-performance-of%C3%A2-al-2-o-3-water-based-nanofluid-lubricants-with-tannic-acid-and-carboxymethyl-cellulose-over%C3%A2-sdbs-as-surfactant
#33
JOURNAL ARTICLE
Dieter Rahmadiawan, Shih-Chen Shi
In this research work, the stability, tribological, and corrosion properties of a water-based Al2 O3 nanofluid (0.5 wt%) formulated with tannin acid (TA) and carboxymethyl cellulose (CMC) as dispersants or surfactants were investigated. For comparative purposes, sodium dodecylbenzene sulfonate (SDBS) was also incorporated. The stability of the nanofluid was assessed through zeta potential measurements and photo-capturing, revealing the effectiveness of TA and CMC in preventing nanoparticle agglomeration...
April 22, 2024: Scientific Reports
https://read.qxmd.com/read/38649277/reorientation-of-hydrogen-bonds-renders-unusual-enhancement-in-thermal-transport-of-water-in-nanoconfined-environments
#34
JOURNAL ARTICLE
Yuan Gao, Ziqiao Chen, Yue Zhang, Yanwei Wen, Xiaotong Yu, Bin Shan, Baoxing Xu, Rong Chen
Liquid confined in a nanochannel or nanotube has exhibited a superfast transport phenomenon, providing an ideal heat and mass transfer platform to meet the increasingly stringent challenge of thermal management in developing high-power-density nanoelectronics and nanochips. However, understanding the thermal transport of confined liquid is currently lacking and is speculated to be fundamentally different from that of bulk counterparts due to the unprecedented thermodynamics of liquid in nanoconfined environments...
April 22, 2024: Nano Letters
https://read.qxmd.com/read/38638978/assessing-the-cooling-lubricating-agencies-for-sustainable-alternatives-during-machining-of-nimonic-80-economic-and-environmental-impacts
#35
JOURNAL ARTICLE
Mayur A Makhesana, Harsh Vesuwala, Kaushik M Patel, Ana Vafadar, Murat Sarikaya, Navneet Khanna
Developing sustainable manufacturing methods that balance environmental and economic aspects is challenging. A comprehensive analysis of the economics of machining and carbon emissions is essential to encourage adopting sustainable practices. This work presents the machinability and comparative sustainability analysis of Nimonic 80 superalloy when it is machined utilizing a novel, environmentally friendly vegetable oil-based hybrid nanofluid-minimum quantity lubrication (MQL) and liquid carbon dioxide (LCO2 ) technique...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38633639/performance-evaluation-of-nanofluid-based-photovoltaic-thermal-pvt-system-with-regression-analysis
#36
JOURNAL ARTICLE
A K Azad, Salma Parvin, Tahiya Hossain
The recent global energy crisis has shocked Bangladesh's power sectors, and experts recommend using alternative energy sources to conserve natural gas, fossil fuels, and electricity. Numerous investigations on the photovoltaic thermal (PVT) system have been carried out to get the source efficiently. As a result, a parametric evaluation of the PVT system's efficiency in Dhaka, Bangladesh, is investigated numerically using CNT nanofluid as a coolant. The numerical simulation is performed using the Galerkin weighted residual based finite element method...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38633633/comparative-simulation-of-nonlinear-radiative-nano-casson-and-maxwell-fluids-with-periodic-magnetic-force-and-sensitivity-analysis
#37
JOURNAL ARTICLE
Saiful Islam, Md Yousuf Ali, Sk Reza-E-Rabbi
This study investigated cyclic magneto-hydrodynamic radiative effects in Casson and Maxwell fluids, including nonlinear radiation and Arrhenius activation energy. It promotes non-Newtonian fluid use in diverse fields like industry, manufacturing, sciences, medicine, and engineering. Using boundary layer approximations, non-dimensional equations are formulated. For numerical solutions, widely recognized explicit finite difference method (EFDM) has been utilized. To ensure the robustness of EFDM results, stability and convergence tests are performed...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38628761/assessment-of-thermohydraulic-performance-and-entropy-generation-in-an-evacuated-tube-solar-collector-employing-pure-water-and-nanofluids-as-working-fluids
#38
JOURNAL ARTICLE
Oscar A López-Núñez, F Lara, A González-Angeles, A Cardenas-Robles, J J Ramírez-Minguela, J Arturo Alfaro-Ayala
This study conducts a numerical comparison of the thermal performance of three distinct working fluids (pure water, TiO2 , and SiO2 water-based nanofluids) within an evacuated tube solar collector using Computational Fluid Dynamics. The study evaluates thermohydraulic performance alongside global and local entropy generation rates, while considering variations in solar radiation values and inlet mass flow rates. Results indicate that nanofluids demonstrate superior performance under low solar radiation, exhibiting higher outlet temperatures, velocities, thermal efficiency, and exergy efficiency compared to pure water...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38625473/thermal-properties-analysis-and-thermal-cycling-of-hitec-molten-salt-with-h-bn-nanoparticles-for-csp-thermal-energy-storage-applications
#39
JOURNAL ARTICLE
Subbarama Kousik Suraparaju, Hatem Ahmad Aljaerani, Mahendran Samykano, Kumaran Kadirgama, Muhamad Mat Noor, Sendhil Kumar Natarajan
Molten salts are the operational fluid for most concentrated solar power (CSP) systems, which has attracted more attention among the scientific community due to the augmentation of their properties with the doping of nanoparticles. Hexagonal boron nitride (h-BN) nanoparticles were dispersed in HITEC molten salt to create a novel nanofluid and evaluate the h-BN nanoparticles' influence on HITEC thermophysical properties. The influence of nanoparticle concentration (0.1, 0.5, and 1wt.%) of h-BN and HITEC was studied in this research...
April 16, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38623688/layer-by-layer-assembly-of-homopolypeptide-polyelectrolytes-on-asymmetric-nanochannels-for-the-detection-of-nickel-ions
#40
JOURNAL ARTICLE
Pengrong An, Jincan Yang, Tianming Wang, Saiwen Lu, Dehao Wang, Zhuoyue Wang, Chun-Lin Sun, Chuanguang Qin, Jun Li
Nickel stands out as one of the prevalent heavy metal ionic pollutants found in water. It is urgent to devise a simple, efficient, budget-friendly, highly-selective and proficient method for detecting Ni(II). This work reports an approach to design a nanofluidic diode for the ultrasensitive and label-free detection of nickel ions based on layer-by-layer assembly of polyarginine (PA) and polyglutamic acid (γ-PGA) on the inner surface of asymmetric nanochannels. We can tune the adsorption/desorption characteristics of the asymmetric nanochannels for Ni2+ by adjusting the pH changes, i...
April 16, 2024: Analytical Methods: Advancing Methods and Applications
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