Kessarin Thanapirom, Sombat Treeprasertsuk, Ashok Choudhury, Nipun Verma, Radha Krishan Dhiman, Mamun Al Mahtab, Harshad Devarbhavi, Akash Shukla, Saeed Sadiq Hamid, Wasim Jafri, Soek Siam Tan, Guan H Lee, Hasmik Ghazinyan, Ajit Sood, Dong Joon Kim, C E Eapen, Han Tao, Nan Yuemin, A Kadir Dokmeci, Manoj Sahu, Anil Arora, Ashish Kumar, Ramesh Kumar, V G Mohan Prasad, Ananta Shresta, Jose Sollano, Diana Alcantara Payawal, George Lau, Shiv Kumar Sarin
The relationship between ammonia and liver-related complications (LRCs) in acute-on-chronic liver failure (ACLF) patients is not clearly established. This study aimed to evaluate the association between ammonia levels and LRCs in patients with ACLF. The study also evaluated the ability of ammonia in predicting mortality and progression of LRCs. The study prospectively recruited ACLF patients based on the APASL definition from the ACLF Research Consortium (AARC) from 2009 to 2019. LRCs were a composite endpoint of bacterial infection, overt hepatic encephalopathy (HE), and ascites...
March 9, 2024: Scientific Reports