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https://www.readbyqxmd.com/read/27898469/update-on-pigment-dispersion-syndrome-and-pigmentary-glaucoma
#1
Kingsley Okafor, Kateki Vinod, Steven J Gedde
PURPOSE OF REVIEW: The present article reviews the clinical features and pathogenesis of pigment dispersion syndrome and pigmentary glaucoma and provides an update regarding their diagnosis and management. RECENT FINDINGS: Newer imaging modalities including ultrasound biomicroscopy and anterior segment optical coherence tomography facilitate visualization of the iris concavity characteristic of eyes with pigment dispersion syndrome and pigmentary glaucoma. Patients with pigmentary glaucoma may be distinguished from those with other glaucoma types by the presence of typical symptoms, personality type, and patterns of diurnal intraocular pressure fluctuation...
November 25, 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27848022/is-there-a-change-in-the-quality-of-life-comparing-the-micro-invasive-glaucoma-surgery-migs-and-the-filtration-technique-trabeculectomy-in-glaucoma-patients
#2
Milena Pahlitzsch, Matthias K J Klamann, Marie-Luise Pahlitzsch, Johannes Gonnermann, Necip Torun, Eckart Bertelmann
PURPOSE: This study was conducted to assess the impact on the Quality of Life (QOL) of micro-invasive glaucoma surgery (MIGS: iStent, Trabectome) and a penetrating technique such as Trabeculectomy (TE). METHODS: This study evaluated 88 eyes of 88 open angle glaucoma patients undergoing glaucoma surgery: 43 (mean age 72.8 ± 8.8y, female 59.5 %, male 40.5 %) Trabectome (NeoMedix, Inc., Tustin, CA, USA), 20 (mean age 68.6 ± 16.4y, female 60 %, male 40 %) iStent (Glaucos Corporation, Laguna Hills, CA, USA), and 25 TE patients (mean age 74...
November 15, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27815624/contralateral-eye-comparison-study-in-mics-migs-trabectome%C3%A2-vs-istent-inject%C3%A2
#3
Johannes Gonnermann, Eckart Bertelmann, Milena Pahlitzsch, Anna-Karina B Maier-Wenzel, Necip Torun, Matthias K J Klamann
PURPOSE: To compare the safety and efficacy profile after combined micro-incision cataract surgery (MICS) and micro-invasive glaucoma surgery (MIGS) with the ab interno trabeculectomy (Trabectome®) in one eye versus two iStent® inject devices in the contralateral eye in patients with open-angle glaucoma (OAG) and cataract. METHODS: This retrospective, intraindividual eye comparison study included 27 patients (54 eyes) who were treated with combined MICS and ab interno trabeculectomy (group I, Trabectome®) in one eye and two iStent® inject devices (group II, GTS 400) in the fellow eye...
November 4, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27314234/the-new-era-of-glaucoma-micro-stent-surgery
#4
Demetrios T Manasses, Leon Au
Minimally invasive glaucoma surgery (MIGS) has been gaining popularity over the last decade. Although there is no strict definition for MIGS, all the new procedures share the common theme of intraocular pressure reduction with minimal tissue destruction, short surgical time, simple instrumentation and fast postoperative recovery. The use of glaucoma drainage implants has long been the traditional treatment for complex glaucoma, but a new wave of glaucoma micro-stents are now being manufactured with various materials designed to increase aqueous outflow via different channels...
June 17, 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27217122/managing-coexistent-cataract-and-glaucoma-with-istent
#5
Christine L Larsen, Thomas W Samuelson
The iStent is an intraocular implant that resides within Schlemm canal and allows for direct bypass of the trabecular meshwork by aqueous fluid. It is one of several procedures termed microinvasive glaucoma surgery. The prominence of microinvasive glaucoma surgery is growing because of its role in lowering intraocular pressure in mild to moderate glaucoma combined with its favorable safety profile. With transcleral glaucoma filtering surgery, there is an increased potential for significant complications including hypotony, suprachoroidal hemorrhage, and long-term risk of endophthalmitis...
May 20, 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/26995503/combined-phacoemulsification-and-xen45-surgery-from-a-temporal-approach-and-2-incisions
#6
V T Pérez-Torregrosa, Á Olate-Pérez, M Cerdà-Ibáñez, A Gargallo-Benedicto, V Osorio-Alayo, A Barreiro-Rego, A Duch-Samper
OBJECTIVE: To assess the safety and effectiveness of phacoemulsification combined with XEN45 implant surgery in patients with cataract and open-angle glaucoma, with 12-month follow-up. METHODS: A prospective study conducted on 30 eyes requiring phacoemulsification with, at least, 2 medications to control intraocular pressure (IOP). Phacoemulsification combined with XEN45 implant surgery was performed within 15minutes of administering subconjunctival mitomycin C...
September 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/26869753/minimally-invasive-glaucoma-surgery-current-status-and-future-prospects
#7
REVIEW
Grace M Richter, Anne L Coleman
Minimally invasive glaucoma surgery aims to provide a medication-sparing, conjunctival-sparing, ab interno approach to intraocular pressure reduction for patients with mild-to-moderate glaucoma that is safer than traditional incisional glaucoma surgery. The current approaches include: increasing trabecular outflow (Trabectome, iStent, Hydrus stent, gonioscopy-assisted transluminal trabeculotomy, excimer laser trabeculotomy); suprachoroidal shunts (Cypass micro-stent); reducing aqueous production (endocyclophotocoagulation); and subconjunctival filtration (XEN gel stent)...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/26380916/the-development-of-a-micro-shunt-made-from-poly-styrene-block-isobutylene-block-styrene-to-treat-glaucoma
#8
Leonard Pinchuk, Isabelle Riss, Juan F Batlle, Yasushi P Kato, John B Martin, Esdras Arrieta, Paul Palmberg, Richard K Parrish, Bruce A Weber, Yongmoon Kwon, Jean-Marie Parel
Glaucoma is the second leading cause of blindness with ∼70 million people worldwide who are blind from this disease. The currently practiced trabeculectomy surgery, the gold standard treatment used to stop the progression of vision loss, is rather draconian, traumatic to the patient and requires much surgical skill to perform. This article summarizes the more than 10-year development path of a novel device called the InnFocus MicroShunt®, which is a minimally invasive glaucoma drainage micro-tube used to shunt aqueous humor from the anterior chamber of the eye to a flap formed under the conjunctiva and Tenon's Capsule...
September 18, 2015: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/25931808/a-review-of-the-istent-%C3%A2-trabecular-micro-bypass-stent-safety-and-efficacy
#9
REVIEW
Sarah R Wellik, Elizabeth A Dale
There is a significant demand for procedures that can effectively treat glaucoma with low risk and good visual outcomes. To fill this void, procedures termed "minimally invasive glaucoma surgery", are gaining in popularity. This review will focus on the safety and efficacy of one such minimally invasive glaucoma surgery procedure, the trabecular micro-bypass stent. This stent is intended to lower intraocular pressure by directly cannulating Schlemm's canal and thereby enhancing aqueous outflow. Recent randomized controlled trials and case series have demonstrated the micro-bypass stent to be a relatively safe procedure, with limited complications and no serious adverse sequelae...
2015: Clinical Ophthalmology
https://www.readbyqxmd.com/read/25747677/supraciliary-micro-stent-implantation-for-open-angle-glaucoma-failing-topical-therapy-1-year-results-of-a-multicenter-study
#10
RANDOMIZED CONTROLLED TRIAL
Julian García-Feijoo, Magda Rau, Swaantje Grisanti, Salvatore Grisanti, Helmut Höh, Carl Erb, Pravoslava Guguchkova, Iqbal Ahmed, Günther Grabner, Herbert Reitsamer, Tarek Shaarawy, Tsontcho Ianchulev
PURPOSE: To evaluate the safety and efficacy of a supraciliary micro-stent (CyPass Micro-Stent; Transcend Medical, Menlo Park, California, USA) for surgical treatment of glaucoma in patients refractory to topical medications. DESIGN: Multicenter, single-arm interventional study. METHODS: Patients with open-angle glaucoma (Shaffer Grade 3 and 4) and uncontrolled medicated intraocular pressure (IOP) >21 mm Hg at baseline and candidates for conventional glaucoma surgery were enrolled...
June 2015: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/25624671/trabecular-micro-bypass-shunt-istent%C3%A2-basic-science-clinical-and-future
#11
REVIEW
E Randy Craven
The trabecular bypass stent offers an alternative to filtration surgery. Patients who may be ideal candidates for considering this procedure are those with prior conjunctival surgery; for example, those who had a 360° peritomy from a scleral buckle might not do well with a trabeculectomy and there is no space for a tube. Highly myopic patients do not tolerate hypotony well, and the iSTB may be an option for some of these patients. I have used the iSTB in patients on anticoagulants who could not stop them, and they needed something beyond medications and laser to lower the IOP in subjects with open-angle glaucoma...
January 2015: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/25518075/-micro-invasive-glaucoma-surgery
#12
REVIEW
Asaf Achiron, Nardeen Sharif, Romi Noy Achiron, Sagee Nisimov, Sagee Burgansky-Eliash
Intraocular pressure (IOP) reduction is the current treatment in glaucoma. In recent years, minimally invasive glaucoma surgery (MIGS) has been added to the arsenal of surgical options. MIGS can reduce trabecular meshwork resistance to outflow and decrease the IOP with mild side effects. In this article, we review the clinical experience gathered with iSTENT, Bypass, Gold Micro Shunt and the Trabectome.
October 2014: Harefuah
https://www.readbyqxmd.com/read/25510636/micro-invasive-suture-trabeculotomy-after-canaloplasty-preliminary-results
#13
Bogomil Voykov, Peter Szurman, Spyridon Dimopoulos, Focke Ziemssen, Omar Alnahrawy
BACKGROUND: In this study, a conjunctival-sparing ab interno approach for circumferential trabeculotomy, termed micro-invasive suture trabeculotomy (MIST) and its preliminary results are presented. DESIGN: Retrospective case-series in a university setting. PARTICIPANTS: A total of 31 patients with open-angle glaucoma with history of canaloplasty. METHODS: A conjunctival-sparing ab interno approach for circumferential trabeculotomy, termed MIST...
July 2015: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/25284980/istent-trabecular-micro-bypass-stent-for-open-angle-glaucoma
#14
REVIEW
Kim Le, Hady Saheb
Trabecular micro-bypass stents, commonly known as iStents, are micro-invasive glaucoma surgery (MIGS) devices used to treat open-angle glaucoma. Like other MIGS procedures that enhance trabecular outflow, the iStent lowers intraocular pressure (IOP) by creating a direct channel between the anterior chamber and Schlemm's canal. iStents are typically implanted at the time of phacoemulsification for patients with open-angle glaucoma and visually significant cataracts. This review summarizes the published data regarding the efficacy, safety, and cost considerations of trabecular micro-bypass stents...
2014: Clinical Ophthalmology
https://www.readbyqxmd.com/read/24648713/characterization-of-micro-invasive-trabecular-bypass-stents-by-ex-vivo-perfusion-and-computational-flow-modeling
#15
Kendall S Hunter, Todd Fjield, Hal Heitzmann, Robin Shandas, Malik Y Kahook
Micro-invasive glaucoma surgery with the Glaukos iStent® or iStent inject® (Glaukos Corporation, Laguna Hills, CA, USA) is intended to create a bypass through the trabecular meshwork to Schlemm's canal to improve aqueous outflow through the natural physiologic pathway. While the iStent devices have been evaluated in ex vivo anterior segment models, they have not previously been evaluated in whole eye perfusion models nor characterized by computational fluid dynamics. Intraocular pressure (IOP) reduction with the iStent was evaluated in an ex vivo whole human eye perfusion model...
2014: Clinical Ophthalmology
https://www.readbyqxmd.com/read/24550367/improvement-in-outflow-facility-by-two-novel-microinvasive-glaucoma-surgery-implants
#16
Cassandra L Hays, Vikas Gulati, Shan Fan, Thomas W Samuelson, Iqbal Ike K Ahmed, Carol B Toris
PURPOSE: To determine improvement in outflow facility (C) in human anterior segments implanted with a novel Schlemm's canal scaffold or two trabecular micro-bypasses. METHODS: Human anterior segments were isolated from 12 pairs of eyes from donors with no history of ocular disease and then perfused at 50, 40, 30, 20, and 10 mm Hg pressures for 10 minutes each. Baseline C was calculated from perfusion pressures and flow rates. The scaffold was implanted into Schlemm's canal of one anterior segment, and two micro-bypasses were implanted three clock-hours apart in the contralateral anterior segment...
March 2014: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/24452726/prospective-unmasked-evaluation-of-the-istent%C3%A2-inject-system-for-open-angle-glaucoma-synergy-trial
#17
MULTICENTER STUDY
Lilit Voskanyan, Julián García-Feijoó, Jose I Belda, Antonio Fea, Anselm Jünemann, Christophe Baudouin
INTRODUCTION: Micro-invasive glaucoma surgical implantation of trabecular micro-bypass stents, previously shown to be safe and effective for open-angle glaucoma (OAG) subjects during cataract surgery, was considered for evaluation as a sole procedure. The aim of this study was to evaluate the safety and intraocular pressure (IOP)-lowering efficacy after ab interno implantation of two Glaukos Trabecular Micro-Bypass iStent inject second generation devices in subjects with OAG. This study was performed at sites in France, Germany, Italy, Republic of Armenia, and Spain...
February 2014: Advances in Therapy
https://www.readbyqxmd.com/read/23958836/-supraciliary-microstent-for-open-angle-glaucoma-clinical-results-of-a-prospective-multicenter-study
#18
MULTICENTER STUDY
S Grisanti, E Margolina, H Hoeh, M Rau, C Erb, I Kersten-Gomez, H B Dick, S Grisanti
PURPOSE: The suprachoroidal CyPass micro-stent is designed to be implanted into the supraciliary space to facilitate aqueous outflow along the uveoscleral pathway in patients with open-angle glaucoma (OAG). This study assessed the safety of micro-stent implantation in patients undergoing cataract surgery. METHODS: In this multicenter study the CyPass microstent was implanted in patients with OAG undergoing cataract surgery. The implantation was performed using a minimally invasive, conjunctiva-sparing, ab interno intervention...
June 2014: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/23074513/intrastromal-corneal-ring-implants-for-corneal-thinning-disorders-an-evidence-based-analysis
#19
(no author information available yet)
OBJECTIVE: The purpose of this project was to determine the role of corneal implants in the management of corneal thinning disease conditions. An evidence-based review was conducted to determine the safety, effectiveness and durability of corneal implants for the management of corneal thinning disorders. The evolving directions of research in this area were also reviewed. SUBJECT OF THE EVIDENCE-BASED ANALYSIS: The primary treatment objectives for corneal implants are to normalize corneal surface topography, improve contact lens tolerability, and restore visual acuity in order to delay or defer the need for corneal transplant...
2009: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/22249233/micro-invasive-glaucoma-surgery-current-perspectives-and-future-directions
#20
REVIEW
Hady Saheb, Iqbal Ike K Ahmed
PURPOSE OF REVIEW: There is an increasing interest and availability of micro-invasive glaucoma surgery (MIGS) procedures. It is important that this increase is supported by sound, peer-reviewed evidence. This article will define MIGS, review relevant publications in the period of annual review and discuss future directions. RECENT FINDINGS: The results of the pivotal trial comparing a trabecular micro-bypass stent (iStent, Glaukos Corporation, Laguna Hills, CA, USA) combined with phacoemulsification to phacoemulsification alone showed a significantly higher percentage of patients with unmedicated intraocular pressure (IOP) ≤ 21 mmHg, and a comparable safety profile...
March 2012: Current Opinion in Ophthalmology
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