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https://www.readbyqxmd.com/read/29351713/-living-with-localized-prostate-cancer-decision-making-and-coping-with-the-illness
#1
Friederike Kendel, Isabella Otto, Jennifer Engler, Mark Schrader, Christine Holmberg
BACKGROUND: Men diagnosed with localized prostate cancer must make a choice between treatment strategies that differ considerably in their side effects and have different long-term requirements for coping with the disease. The aim of this study was to describe how men perceive their treatment decision retrospectively and which coping strategies they use. MATERIAL & METHODS: Fifteen men (age mean=67.13±9.38 years) diagnosed with localized prostate cancer participated in three focus groups, grouped according to the treatment strategies radical prostatectomy, radiotherapy, and active surveillance...
January 19, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29351712/-immigrated-physicians-chances-and-challenges
#2
Isabel Hohmann, Heide Glaesmer, Yuriy Nesterko
BACKGROUND AND OBJECTIVE: In the health care infrastructure of Germany a demand for physicians with immigrant background exists. The situation of immigrated physicians is largely unexplored so far. In the framework of a pilot study stressors and resources of physicians with immigrant background have been explored concerning their migration-related experiences at German hospitals, and within the medical team. METHODS: As part of a qualitative analysis 8 physicians with immigrant background have been interviewed (problem-centered interview) from July to September 2014...
January 19, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29351662/the-versatile-tanycyte-a-hypothalamic-integrator-of-reproduction-and-energy-metabolism
#3
Vincent Prevot, Bénédicte Dehouck, Ariane Sharif, Philippe Ciofi, Paolo Giacobini, Jerome Clasadonte
The fertility and survival of an individual rely on the ability of the periphery to promptly, effectively and reproducibly communicate with brain neural networks that control reproduction, food intake and energy homeostasis. Tanycytes, a specialized glial cell type lining the wall of the third ventricle in the median eminence of the hypothalamus, appear to act as the linchpin of these processes by dynamically controlling the secretion of neuropeptides into the portal vasculature by hypothalamic neurons and regulating blood-brain and blood-cerebrospinal fluid exchanges, both processes that depend on the ability of these cells to adapt their morphology to the physiological state of the individual...
January 17, 2018: Endocrine Reviews
https://www.readbyqxmd.com/read/29351607/sector-wide-or-disease-specific-implications-of-trends-in-development-assistance-for-health-for-the-sdg-era
#4
Anne L Buffardi
The record of the Millennium Development Goals broadly reflects the trade-offs of disease-specific financing: substantial progress in particular areas, facilitated by time-bound targets that are easy to measure and communicate, which shifted attention and resources away from other areas, masked inequalities and exacerbated fragmentation. In many ways, the Sustainable Development Goals reflect a profound shift towards a more holistic, system-wide approach. To inform responses to this shift, this article builds upon existing work on aggregate trends in donor financing, bringing together what have largely been disparate analyses of sector-wide and disease-specific financing approaches...
January 16, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29351574/self-reported-knowledge-correct-knowledge-and-use-of-uk-drinking-guidelines-among-a-representative-sample-of-the-english-population
#5
Penny Buykx, Jessica Li, Lucy Gavens, Lucie Hooper, Elena Gomes de Matos, John Holmes
Aims: Promotion of lower risk drinking guidelines is a commonly used public health intervention with various purposes, including communicating alcohol consumption risks, informing drinkers' decision-making and, potentially, changing behaviour. UK drinking guidelines were revised in 2016. To inform potential promotion of the new guidelines, we aimed to examine public knowledge and use of the previous drinking guidelines, including by population subgroup. Methods: A demographically representative, cross-sectional online survey of 2100 adults living in England in July 2015 (i...
January 17, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29351571/the-barriers-and-facilitators-for-recognising-distress-in-people-with-severe-dementia-on-general-hospital-wards
#6
G J E Crowther, C A Brennan, M I Bennett
Introduction: psychological symptoms and delirium are common, but underreported in people with dementia on hospital wards. Unrecognised and untreated symptoms can manifest as distress. Identifying distress accurately therefore could act as a trigger for better investigation and treatment of the underlying causes. The challenges faced by healthcare professionals to recognise and report distress are poorly understood. Methods: semi-structured interviews with a purposive sample of 25 healthcare professionals working with older people in general hospitals were conducted...
January 17, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29351520/beyond-clinical-complexity-non-medical-barriers-to-nursing-home-care-for-rural-residents
#7
Carrie Henning-Smith, Katy B Kozhimannil, Michelle M Casey, Shailendra Prasad
We conducted a qualitative content analysis of barriers to nursing home admission for rural residents. Data came from semi-structured interviews with 23 rural hospital discharge planners across five states (Georgia, Idaho, Minnesota, Pennsylvania, and Wisconsin). From those, we identified four themes around non-medical barriers to rural nursing home placement with particular salience in rural areas: financial issues; transportation; nursing home availability and infrastructure; and timeliness. We also identified policy and programmatic interventions across four themes: loosen bureaucratic requirements; improve communication between facilities; increase rural long-term care capacity; and address underlying social determinants of health...
January 19, 2018: Journal of Aging & Social Policy
https://www.readbyqxmd.com/read/29351513/neuroimmune-interactions-from-the-brain-to-the-immune-system-and-vice-versa
#8
Robert Dantzer
Because of the compartmentalization of disciplines that shaped the academic landscape of biology and biomedical sciences in the past, physiological systems have long been studied in isolation from each other. This has particularly been the case for the immune system. As a consequence of its ties with pathology and microbiology, immunology as a discipline has largely grown independently of physiology. Accordingly, it has taken a long time for immunologists to accept the concept that the immune system is not self-regulated but functions in close association with the nervous system...
January 1, 2018: Physiological Reviews
https://www.readbyqxmd.com/read/29351499/graduate-speech-language-pathology-students-initial-self-perceptions-of-skills-critical-for-interprofessional-practice
#9
Courtney Karasinski, Janine L Schmedding-Bartley
Interprofessional collaborative practice is critical for quality service delivery. Given the limited research on speech-language pathology (SLP) students' interprofessional knowledge and skills, this investigation assessed graduate SLP students' self-perceived interprofessional competence and their perceptions of roles of other professionals. Fifty-eight SLP students completed two validated surveys at the beginning of the first or second semester of graduate school. Collectively, the students rated themselves positively on communication, teamwork, attitudes toward interprofessional learning, and professional relationships...
January 19, 2018: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29351483/prenatal-exposure-to-diesel-exhaust-pm2-5-causes-offspring-%C3%AE-cell-dysfunction-in-adulthood
#10
Minjie Chen, Shuai Liang, Xiaobo Qin, Li Zhang, Lianglin Qiu, Sufang Chen, Ziying Hu, Yanyi Xu, Wanjun Wang, Yuhao Zhang, Qi Cao, Zhekang Ying
BACKGROUND: Environmental stressors that encounter in early-life and cause abnormal fetal and/or neonatal development may increase susceptibility to non-communicable diseases such as diabetes. Maternal exposure to ambient fine particulate matter (PM2.5) is associated with various fetal abnormalities, suggesting that it may program offspring's susceptibility to diabetes. In the present study, we therefore examined whether maternal exposure to diesel exhaust PM2.5 (DEP), one of the major sources of ambient PM2...
December 26, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29351444/activated-human-t-lymphocytes-inhibit-tgf%C3%AE-induced-fibroblast-to-myofibroblast-differentiation-via-prostaglandins-d2-and-e2
#11
Shannon H Lacy, Amali P Epa, Stephen J Pollock, Collynn F Woeller, Thomas H Thatcher, Richard P Phipps, Patricia J Sime
In pulmonary fibrosis (PF), fibroblasts and myofibroblasts proliferate and deposit excessive extracellular matrix in the interstitium, impairing normal lung function. As most forms of PF have a poor prognosis and limited treatment options, PF represents an urgent unmet need for novel, effective therapeutics. While the role of immune cells in lung fibrosis is unclear, recent studies suggest that T lymphocyte (T cell) activation may be impaired in PF patients. Further, we have previously shown that activated T cells can produce prostaglandins with anti-scarring potential...
December 20, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/29351367/accurate-understanding-of-infertility-risk-among-families-of-adolescent-males-newly-diagnosed-with-cancer
#12
Vicky Lehmann, Jessica S Flynn, Rebecca H Foster, Kathryn M Russell, James L Klosky
OBJECTIVE: To examine patient and parent understanding of infertility risk (relative to oncologists' risk ratings) among adolescents newly diagnosed with cancer, and to identify background factors related to inaccurate reporting/estimating. METHODS: Male patients (N=137; aged 13-21) and their parents completed self-report questionnaires. Those who reported a fertility-related conversation with their provider (N=102 adolescents, N=74 parents), reported their infertility risk (i...
January 19, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29351364/the-ethical-foundations-of-risk-analysis
#13
Daniel J Rozell
In the field of risk analysis, the normative value systems underlying accepted methodology are rarely explicitly discussed. This perspective provides a critique of the various ethical frameworks that can be used in risk assessments and risk management decisions. The goal is to acknowledge philosophical weaknesses that should be considered and communicated in order to improve the public acceptance of the work of risk analysts.
January 19, 2018: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29351358/microfluidics-based-subretinal-chemical-neuromodulation-of-photoreceptor-degenerated-retinas
#14
Corey M Rountree, John B Troy, Laxman Saggere
Purpose: Retinal prostheses can restore rudimentary vision in cases of photoreceptor degeneration through electrical stimulation, but face difficulties achieving high spatial resolution because electrical current is an inherently unnatural stimulus. We investigated the therapeutic feasibility of using patterned delivery of the glutamate neurotransmitter, a primary agent of natural synaptic communication of the retina, as a biomimetic chemical alternative to electrical current for neuromodulation of photoreceptor degenerate retina...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29351354/the-effects-of-intensive-speech-treatment-on-conversational-intelligibility-in-spanish-speakers-with-parkinson-s-disease
#15
Gemma Moya-Galé, Alireza Goudarzi, Àngels Bayés, Megan McAuliffe, Bram Bulté, Erika S Levy
Purpose: The purpose of this study was to examine the effects of intensive speech treatment on the conversational intelligibility of Castilian Spanish speakers with Parkinson's disease (PD), as well as on the speakers' self-perceptions of disability. Method: Fifteen speakers with a medical diagnosis of PD participated in this study. Speech recordings were completed twice before treatment, immediately posttreatment, and at a 1-month follow-up session. Conversational intelligibility was assessed in 2 ways-transcription accuracy scores and intelligibility ratings on a 9-point Likert scale...
January 19, 2018: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29351224/n-dimensional-lll-reduction-algorithm-with-pivoted-reflection
#16
Zhongliang Deng, Di Zhu, Lu Yin
The Lenstra-Lenstra-Lovász (LLL) lattice reduction algorithm and many of its variants have been widely used by cryptography, multiple-input-multiple-output (MIMO) communication systems and carrier phase positioning in global navigation satellite system (GNSS) to solve the integer least squares (ILS) problem. In this paper, we propose an n-dimensional LLL reduction algorithm (n-LLL), expanding the Lovász condition in LLL algorithm to n-dimensional space in order to obtain a further reduced basis. We also introduce pivoted Householder reflection into the algorithm to optimize the reduction time...
January 19, 2018: Sensors
https://www.readbyqxmd.com/read/29351195/seeing-context-through-metaphor-using-communications-research-to-bring-a-social-determinants-perspective-to-public-thinking-about-child-abuse-and-neglect
#17
Nathaniel Kendall-Taylor, Kate Stanley
Human beings think in metaphor and reason through analogy. The metaphors through which we think influence how we understand and feel about social issues as well as the actions that we see as appropriate and important. Metaphors can be used to increase understanding of how issues work and increase the salience of a given issue, build support for programs and policies necessary to address the issue, and instigate demand for change and civic action. In this paper, we use a mixed methods research design, including brief qualitative interviews, experimental surveys, and focus groups, to test the ability of different metaphors to influence public understanding of the social determinants of child abuse and neglect in the UK...
January 19, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29351109/coordination-of-the-environmental-influences-on-child-health-outcomes-program-so-the-whole-is-greater-than-the-sum-of-its-parts
#18
Brian Smith, Susan Knox, Daniel K Benjamin
PURPOSE OF REVIEW: The Environmental influences on Child Health Outcomes (ECHO) program's mission is to enhance the health of children for generations to come. In this manuscript, we describe the structure of the ECHO Coordinating Center (ECHO-CC) and its role in developing the infrastructure for the ECHO program. RECENT FINDINGS: The ECHO-CC supports ECHO's mission by developing the framework of the ECHO program, coordinating multiple levels of membership in the ECHO community, developing ECHO policies and procedures, and fostering communication and engagement inside and outside of ECHO...
January 17, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29351046/young-adults-experience-of-appearance-altering-orthognathic-surgery-a-longitudinal-interpretative-phenomenologic-analysis
#19
Morna J Liddle, Sarah R Baker, Keith G Smith, Andrew R Thompson
OBJECTIVE: To gain an experiential account of the processes of change associated specifically with orthognathic surgery. DESIGN: A qualitative design was used. Semistructured interviews were carried out with 7 participants approximately 1 week before and 6-8 weeks after surgery. The data were analyzed using interpretative phenomenologic analysis (IPA). SETTING: Participants were recruited from a NHS Dental Hospital. PARTICIPANTS: Patients aged 16 to 25 years scheduled to undergo orthognathic surgery on both the upper and lower jaws were purposively sought to participate...
February 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29351026/the-influences-of-child-intelligibility-and-rate-on-caregiver-responses-to-toddlers-with-and-without-cleft-palate
#20
Jennifer R Frey, Ann P Kaiser, Nancy J Scherer
OBJECTIVE: The purpose of this study was to investigate the influences of child speech intelligibility and rate on caregivers' linguistic responses. DESIGN: This study compared the language use of children with cleft palate with or without cleft lip (CP±L) and their caregivers' responses. Descriptive analyses of children's language and caregivers' responses and a multilevel analysis of caregiver responsivity were conducted to determine whether there were differences in children's productive language and caregivers' responses to different types of child utterances...
February 2018: Cleft Palate-craniofacial Journal
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