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https://www.readbyqxmd.com/read/28813891/quantitative-assessment-of-paretic-limb-dexterity-and-interlimb-coordination-during-bilateral-arm-rehabilitation-training
#1
Chang Xu, Siyi Li, Kui Wang, Zengguang Hou, Ningbo Yu
In neuro-rehabilitation after stroke, the conventional constrained induced movement therapy (CIMT) has been well-accepted. Existing bilateral trainings are mostly on mirrored symmetrical motion. However, complementary bilateral movements are dominantly involved in activities of daily living (ADLs), and functional bilateral therapies may bring better skill transfer from trainings to daily life. Neurophysiological evidence is also growing. In this work, we firstly introduce our bilateral arm training system realized with a haptic interface and a motion sensor, as well as the tasks that have been designed to train both the manipulation function of the paretic arm and coordination of bilateral upper limbs...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813472/an-intronic-line-1-insertion-in-mertk-is-strongly-associated-with-retinopathy-in-swedish-vallhund-dogs
#2
Richard Everson, Louise Pettitt, Oliver P Forman, Olivia Dower-Tylee, Bryan McLaughlin, Saija Ahonen, Maria Kaukonen, András M Komáromy, Hannes Lohi, Cathryn S Mellersh, Jane Sansom, Sally L Ricketts
The domestic dog segregates a significant number of inherited progressive retinal diseases, several of which mirror human retinal diseases and which are collectively termed progressive retinal atrophy (PRA). In 2014, a novel form of PRA was reported in the Swedish Vallhund breed, and the disease was mapped to canine chromosome 17. The causal mutation was not identified, but expression analyses of the retinas of affected Vallhunds demonstrated a 6-fold increased expression of the MERTK gene compared to unaffected dogs...
2017: PloS One
https://www.readbyqxmd.com/read/28813266/intuitive-parenting-understanding-the-neural-mechanisms-of-parents-adaptive-responses-to-infants
#3
REVIEW
Christine E Parsons, Katherine S Young, Alan Stein, Morten L Kringelbach
When interacting with an infant, parents intuitively enact a range of behaviours that support infant communicative development. These behaviours include altering speech, establishing eye contact and mirroring infant expressions and are argued to occur largely in the absence of conscious intent. Here, we describe studies investigating early, pre-conscious neural responses to infant cues, which we suggest support aspects of parental intuitive behaviour towards infants. This work has provided converging evidence for rapid differentiation of infant cues from other salient social signals in the adult brain...
June 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28811605/spatial-and-viewpoint-selectivity-for-others-observed-actions-in-monkey-ventral-premotor-mirror-neurons
#4
Monica Maranesi, Alessandro Livi, Luca Bonini
The spatial location and viewpoint of observed actions are closely linked in natural social settings. For example, actions observed from a subjective viewpoint necessarily occur within the observer's peripersonal space. Neurophysiological studies have shown that mirror neurons (MNs) of the monkey ventral premotor area F5 can code the spatial location of live observed actions. Furthermore, F5 MN discharge can also be modulated by the viewpoint from which filmed actions are seen. Nonetheless, whether and to what extent MNs can integrate viewpoint and spatial location of live observed actions remains unknown...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811289/primary-tumors-limit-metastasis-formation-through-induction-of-il15-mediated-crosstalk-between-patrolling-monocytes-and-nk-cells
#5
Hiroshi Kubo, Sofia Mensurado, Natacha Goncalves-Sousa, Karine Serre, Bruno Silva-Santos
Metastases are responsible for the vast majority of cancer-related deaths. Although tumor cells can become invasive early during cancer progression, metastases formation typically occurs as a late event. How the immune response to primary tumors may dictate this outcome remains poorly understood, which hampers our capacity to manipulate it therapeutically. Here we used a two-step experimental model, based on the highly aggressive B16F10 melanoma, that temporally segregates the establishment of primary tumors (subcutaneously) and the formation of lung metastases (from intravenous injection)...
August 15, 2017: Cancer Immunology Research
https://www.readbyqxmd.com/read/28809892/beam-folding-analysis-and-optimization-of-mask-enhanced-toroidal-multipass-cells
#6
Manuel Graf, Herbert Looser, Lukas Emmenegger, Béla Tuzson
We present computational and experimental investigations of the beam folding properties and fringe suppression capabilities in monolithic toroidal multipass cells (MPCs) when combined with absorption masks. Coherent field simulations based on the Fresnel-Huygens theory were performed to understand the effect of multiple field truncations in such an optically semi-unstable mirror arrangement. The explicit numerical calculation of the radiation field at each reflection allows detailed optimization and performance analysis...
August 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28809876/sub-100%C3%A2-%C3%A2-fs-tm-mgwo4-laser-at-2017%C3%A2-%C3%A2-nm-mode-locked-by-a-graphene-saturable-absorber
#7
Yicheng Wang, Weidong Chen, Mark Mero, Lizhen Zhang, Haifeng Lin, Zhoubin Lin, Ge Zhang, Fabian Rotermund, Young Jun Cho, Pavel Loiko, Xavier Mateos, Uwe Griebner, Valentin Petrov
We present the first sub-100 fs bulk solid-state laser in the 2-μm spectral range employing the monoclinic Tm(3+)-dopedMgWO4 crystal as an active medium. By applying a graphene-based saturable absorber and chirped mirrors for dispersion management, stable self-starting mode-locked operation at 2017 nm was achieved. Nearly Fourier-limited pulses as short as 86 fs featuring a bandwidth of 53 nm were generated at a repetition rate of 76 MHz. A pulse energy of 1.1 nJ was achieved at 87 MHz for a pulse duration of 96 fs...
August 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28809697/geometric-and-photometric-consistency-in-a-mixed-video-and-galvanoscopic-scanning-laser-projection-mapping-system
#8
Petar Pjanic, Simon Willi, Anselm Grundhofer
We present a geometric calibration method to accurately register a galvanoscopic scanning laser projection system (GLP) based on 2D vector input data onto an arbitrarily complex 3D-shaped projection surface. This method allows for accurate merging of 3D vertex data displayed on the laser projector with geometrically calibrated standard rasterization-based video projectors that are registered to the same geometry. Because laser projectors send out a laser light beam via galvanoscopic mirrors, a standard pinhole model calibration procedure that is normally used for pixel raster displays projecting structured light patterns, such as Gray codes, cannot be carried out directly with sufficient accuracy as the rays do not converge into a single point...
August 10, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28809201/secondary-use-of-ehr-interpreting-clinician-inter-rater-reliability-through-qualitative-assessment
#9
Sarah Mullin, Edwin Anand, Shyamashree Sinha, Buer Song, Jane Zhao, Peter L Elkin
In a retrospective secondary-use EHR study identifying a cohort of Non-Valvular Atrial Fibrillation (NVAF) patients, chart abstraction was done by two sets of clinicians to create a gold standard for risk measures CHA2DS2-VASc and HAS-BLED. Inter-rater reliability between each set of clinicians for NVAF and the outcomes of interest were variable, ranging from extremely low agreement to high agreement. To assess the chart abstraction process, a focus group and a survey was conducted. Survey findings revealed patterns of difficulty in assessing certain items dealing with temporality and social data...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28808234/cascaded-counter-propagating-nonlinear-interactions-in-highly-efficient-sub-%C3%A2%C2%B5m-periodically-poled-crystals
#10
Andrius Zukauskas, Anne-Lise Viotti, Charlotte Liljestrand, Valdas Pasiskevicius, Carlota Canalias
Mirrorless optical parametric oscillators (MOPOs) are very attractive parametric devices that rely on the nonlinear interaction of counter-propagating photons to inherently establish distributed feedback, without the use of external mirrors or surface coatings. These devices offer unique spectral and coherence properties that will benefit a large variety of applications ranging from spectroscopy to quantum communications. The major obstacle in exploiting their full potential is ascribed to the difficulty in engineering a nonlinear material in which the generation of counter-propagating waves can be phase matched...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28807871/mentalizing-regions-represent-distributed-continuous-and-abstract-dimensions-of-others-beliefs
#11
Jorie Koster-Hale, Hilary Richardson, Natalia Velez, Mika Asaba, Liane Young, Rebecca Saxe
The human capacity to reason about others' minds includes making causal inferences about intentions, beliefs, values, and goals. Previous fMRI research has suggested that a network of brain regions, including bilateral temporo-parietal junction (TPJ), superior temporal sulcus (STS), and medial prefrontal-cortex (MPFC), are reliably recruited for mental state reasoning. Here, in two fMRI experiments, we investigate the representational content of these regions. Building on existing computational and neural evidence, we hypothesized that social brain regions contain at least two functionally and spatially distinct components: one that represents information related to others' motivations and values, and another that represents information about others' beliefs and knowledge...
August 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/28807648/not-all-visual-symmetry-is-equal-partially-distinct-neural-bases-for-vertical-and-horizontal-symmetry
#12
Zaira Cattaneo, Silvia Bona, Juha Silvanto
Visual mirror symmetry plays an important role in visual perception in both human and animal vision; its importance is reflected in the fact that it can be extracted automatically during early stages of visual processing. However, how this extraction is implemented at the cortical level remains an open question. Given the importance of symmetry in visual perception, one possibility is that there is a network which extracts all types of symmetry irrespective of axis of orientation; alternatively, symmetry along different axes might be encoded by different brain regions, implying that that there is no single neural mechanism for symmetry processing...
August 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28807608/benefits-of-flu-vaccination-for-persons-with-diabetes-mellitus-a-review
#13
REVIEW
M Goeijenbier, T T van Sloten, L Slobbe, C Mathieu, P van Genderen, Walter E P Beyer, Albert D M E Osterhaus
Diabetes mellitus imposes a significant and increasing burden on society, with major consequences for human health, welfare and the economy worldwide. Persons with diabetes mellitus are at increased risk of developing severe complications after influenza virus infection and guidelines advise vaccination. The present evidence for influenza vaccine effectiveness in persons with diabetes mellitus is mainly based on observational studies with clinical endpoints like hospitalization and death, indicating a beneficial reduction of morbidity and mortality...
August 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28807377/crem-transgene-mice-an-animal-model-of-atrial-fibrillation-and-thrombogenesis
#14
A Bukowska, M Felgendreher, B Scholz, C Wolke, J S Schulte, E Fehrmann, E Wardelmann, M D Seidl, U Lendeckel, K Himmler, A Gardemann, A Goette, F U Müller
BACKGROUND: The molecular pathomechanisms underlying atrial thrombogenesis are multifactorial and still require detailed investigations. Transgenic mice with cardiomyocyte-directed expression of the transcriptional repressor CREM-IbΔC-X (CREM-TG) represent an experimental model of atrial fibrillation (AF) that shows a gradual, age-dependent progression from atrial ectopy to persistent AF. Importantly, this model develops biatrial thrombi. The molecular characteristics related to the thrombogenesis in CREM-TG mice have not been studied, yet...
August 1, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28807317/validation-of-the-famacha%C3%A2-system-in-south-american-camelids
#15
Bobby E Storey, Lisa H Williamson, Sue B Howell, Thomas H Terrill, Roy Berghaus, Anand N Vidyashankar, Ray M Kaplan
Haemonchus contortus resistant to multiple anthelmintics threaten the viability of the small ruminant industry in areas where this parasite is prevalent. In response to this situation, the FAMACHA© system was developed and validated for use with small ruminants as a way to detect clinical anemia associated with haemonchosis. Given that H. contortus and multiple anthelmintic resistance is a similar problem in camelids, the FAMACHA© system might also provide the same benefits. To address this need, a validation study of the FAMACHA© system was conducted on 21 alpaca and llama farms over a 2-year period...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28807278/helminth-infections-on-organic-dairy-farms-in-spain
#16
I Orjales, M Mezo, M Miranda, M González-Warleta, F Rey-Crespo, M Vaarst, S Thamsborg, F J Diéguez, J A Castro-Hermida, M López-Alonso
The aim of this study was to assess the prevalence of the major helminth infections affecting organic dairy cattle in northern Spain. Milk and faecal samples were obtained from 443 milking cows. Ostertagia ostertargi and Fasciola hepatica exposure was assessed by detection of specific antibodies in milk samples and F. hepatica infection was diagnosed by the detection of coproantigens in faecal samples. Dictyocaulus viviparus and Calicophoron daubneyi infections were diagnosed by conventional coprological techniques...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28807031/inflammation-and-pro-resolution-inflammation-after-hepatobiliary-surgery
#17
Juan P Cata, Jose F Velasquez, Maria F Ramirez, Jean-Nicolas Vauthey, Vijaya Gottumukkala, Claudius Conrad, Bradford J Kim, Thomas Aloia
BACKGROUND: The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics of interleukin-6, cortisol, lipoxin A4, and resolvin D in patients who underwent oncologic liver resections. METHODS: All patients gave written informed consent. Demographic and perioperative surgical data were collected, along with blood samples, before surgery and on the mornings of postoperative days 1, 3, and 5...
August 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28806691/mercury-contamination-level-and-speciation-inventory-in-lakes-titicaca-uru-uru-bolivia-current-status-and-future-trends
#18
S Guédron, D Point, D Acha, S Bouchet, P A Baya, E Tessier, M Monperrus, C I Molina, A Groleau, L Chauvaud, J Thebault, E Amice, L Alanoca, C Duwig, G Uzu, X Lazarro, A Bertrand, S Bertrand, C Barbraud, K Delord, F M Gibon, C Ibanez, M Flores, P Fernandez Saavedra, M E Ezpinoza, C Heredia, F Rocha, C Zepita, D Amouroux
Aquatic ecosystems of the Bolivian Altiplano (∼3800 m a.s.l.) are characterized by extreme hydro-climatic constrains (e.g., high UV-radiations and low oxygen) and are under the pressure of increasing anthropogenic activities, unregulated mining, agricultural and urban development. We report here a complete inventory of mercury (Hg) levels and speciation in the water column, atmosphere, sediment and key sentinel organisms (i.e., plankton, fish and birds) of two endorheic Lakes of the same watershed differing with respect to their size, eutrophication and contamination levels...
August 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28805418/adaptation-of-a-nursing-home-culture-change-research-instrument-for-frontline-staff-quality-improvement-use
#19
Christine W Hartmann, Jennifer A Palmer, Whitney L Mills, Camilla B Pimentel, Rebecca S Allen, Nancy J Wewiorski, Kristen R Dillon, A Lynn Snow
Enhanced interpersonal relationships and meaningful resident engagement in daily life are central to nursing home cultural transformation, yet these critical components of person-centered care may be difficult for frontline staff to measure using traditional research instruments. To address the need for easy-to-use instruments to help nursing home staff members evaluate and improve person-centered care, the psychometric method of cognitive-based interviewing was used to adapt a structured observation instrument originally developed for researchers and nursing home surveyors...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28805047/outcomes-of-post-prostatectomy-radiotherapy-at-a-regional-cancer-centre
#20
Luke Nicholls, Amber Winter, Ashley Harwood, Ashley Plank, Preeti Bagga, Winnie Wong, Eric Khoo
INTRODUCTION: To investigate the efficacy and toxicity of radiation therapy (RT) after radical prostatectomy (RP) for prostate cancer at Radiation Oncology Centres, Toowoomba. METHODS: The electronic medical records of 130 consecutive patients with histologically proven prostate adenocarcinoma who underwent post-prostatectomy RT between January 2008 and December 2014 were analysed. Primary endpoint was Biochemical Recurrence (BCR) after RT. BCR was defined by PSA > 0...
August 14, 2017: Journal of Medical Radiation Sciences
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