Changyang Xing, Xinpei Wang, Yuan Gao, Jiaxin Zhang, Yunnan Liu, Yitong Guo, Chen Wang, Yang Feng, Yujia Lei, Xing Zhang, Jia Li, Wendong Hu, Shu Zhang, Lijun Yuan, Feng Gao
KEY POINTS: Rapid alterations of gravitational stress during high-performance aircraft push-pull manoeuvres induce dramatic shifts in volume and pressure within the circulation system, which may result in loss of consciousness due to the rapid and significant reduction in cerebral perfusion. There are still no specific and effective countermeasures so far. We found that lower body negative pressure (LBNP), applied prior to and during -Gz and released at the subsequent transition to +Gz, could effectively counteract gravitational haemodynamic stress induced by a simulated push-pull manoeuvre and improve cerebral diastolic perfusion in human subjects...
August 2020: Journal of Physiology