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https://www.readbyqxmd.com/read/28334145/combined-effects-of-thinning-and-decline-on-fine-root-dynamics-in-a-quercus-robur-l-forest-adjoining-the-italian-pre-alps
#1
E Mosca, L Montecchio, G Barion, C Dal Cortivo, T Vamerali
Aims: Oak decline is a complex phenomenon, characterized by symptoms of canopy transparency, bark cracks and root biomass reduction. Root health status is one of the first stress indicators, and root turnover is a key process in plant adaptation to unfavourable conditions. In this study, the combined effects of decline and thinning were evaluated on fine root dynamics in an oak forest adjoining the Italian Pre-Alps by comparison of acute declining trees with non-declining trees, both with and without thinning treatment of surrounding trees...
February 28, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28294436/purchases-by-heavier-drinking-young-people-concentrated-in-lower-priced-beverages-implications-for-policy
#2
Martin Wall, Sally Casswell, Li-Chia Yeh
INTRODUCTION AND AIMS: Alcohol is an increasingly important risk factor in the global burden of disease. The acute harms experienced and persistence of drinking patterns established in adolescence motivate investigating influences on youth drinking. The aim is to examine association between heavier drinking in young people and their choice of beverage type, purchase outlet and price. DESIGN AND METHODS: A nationally representative sample of New Zealand drinkers (N = 1056) aged 16-19 years recruited using random digit dialling was surveyed in 2012 as part of the International Alcohol Control study...
March 14, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28268001/return-to-duty-following-combat-related-multi-ligamentous-knee-injury
#3
Aaron E Barrow, Andrew J Sheean, Travis C Burns
INTRODUCTION: This retrospective cohort study characterized injury patterns, treatment practices, and identified the return to duty (RTD) rate following combat-related multi-ligament knee injuries (MLKI). PATIENTS AND METHODS: We evaluated injury characteristics and treatment methods of 46 military service members who had sustained a MLKI during combat activity. The primary clinical outcome measure was ability to return to active military duty. Secondary outcomes included subjective pain score, knee motion, knee instability, and use of ambulatory assistive device...
February 22, 2017: Injury
https://www.readbyqxmd.com/read/28247210/age-related-effects-on-maximal-and-rapid-hamstrings-quadriceps-strength-capacities-and-vertical-jump-power-in-young-and-older-females
#4
Ty B Palmer, Brittany N Followay, Brennan J Thompson
BACKGROUND AND AIMS: Declines in hamstrings and quadriceps maximal and rapid strength are commonly reported as a consequence of aging; however, few studies have investigated the influence of age on maximal and rapid hamstrings to quadriceps (H/Q) strength ratios. This study aimed to examine the effects of age on leg extension and flexion maximal and rapid torque production, H/Q strength ratios, and muscle power in healthy, young and old females. METHODS: Fifteen young (21 ± 2 years) and 15 old (69 ± 7 years) females performed 3 isometric leg extension and flexion maximal voluntary contractions (MVCs), from which peak torque (PT), early (0-30 ms) and late (0-200 ms) phase rate of torque development (RTD), and PT and RTD H/Q strength ratios were extracted...
February 28, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28208379/prediction-of-the-moments-in-advection-diffusion-lattice-boltzmann-method-i-truncation-dispersion-skewness-and-kurtosis
#5
Irina Ginzburg
The effect of the heterogeneity in the soil structure or the nonuniformity of the velocity field on the modeled resident time distribution (RTD) and breakthrough curves is quantified by their moments. While the first moment provides the effective velocity, the second moment is related to the longitudinal dispersion coefficient (k_{T}) in the developed Taylor regime; the third and fourth moments are characterized by their normalized values skewness (Sk) and kurtosis (Ku), respectively. The purpose of this investigation is to examine the role of the truncation corrections of the numerical scheme in k_{T}, Sk, and Ku because of their interference with the second moment, in the form of the numerical dispersion, and in the higher-order moments, by their definition...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28205264/the-influence-of-patellar-tendon-and-muscle-tendon-unit-stiffness-on-quadriceps-explosive-strength-in-man
#6
Garry J Massey, Thomas G Balshaw, Thomas M Maden-Wilkinson, Neale A Tillin, Jonathan P Folland
The influence of musculotendinous tissue stiffness on contractile rate of torque development (RTD) remains opaque. This study examined the relationships between both patellar tendon (PT) and vastus lateralis (VL) muscle-tendon unit (MTU) stiffness, and voluntary and evoked knee extension RTD. Fifty-two healthy untrained males completed duplicate laboratory sessions. Absolute and relative RTD was measured at 50 Nm/25%MVT increments from onset and sequentially during explosive voluntary and evoked octet (supramaximal stimulation: [8 pulses at 300 Hz]) isometric contractions...
February 15, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28205144/recommended-best-practices-for-process-monitoring-instrumentation-in-pharmaceutical-freeze-drying-2017
#7
Steven Nail, Serguei Tchessalov, Evgenyi Shalaev, Arnab Ganguly, Ernesto Renzi, Frank Dimarco, Lindsay Wegiel, Steven Ferris, William Kessler, Michael Pikal, Greg Sacha, Alina Alexeenko, T N Thompson, Cindy Reiter, James Searles, Paul Coiteux
Recommended best practices in monitoring of product status during pharmaceutical freeze drying are presented, focusing on methods that apply to both laboratory and production scale. With respect to product temperature measurement, sources of uncertainty associated with any type of measurement probe are discussed, as well as important differences between the two most common types of temperature-measuring instruments-thermocouples and resistance temperature detectors (RTD). Two types of pressure transducers are discussed-thermal conductivity-type gauges and capacitance manometers, with the Pirani gauge being the thermal conductivity-type gauge of choice...
February 15, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28166121/neural-and-muscular-contributions-to-the-age-related-reductions-in-rapid-strength
#8
Gena R Gerstner, Brennan J Thompson, Joseph G Rosenberg, Eric J Sobolewski, Michael J Scharville, Eric D Ryan
INTRODUCTION: The purpose of this study was to investigate the age-related differences in absolute and normalized plantarflexion rate of torque development (RTD) at early (0-50 ms) and late (100-200 ms) time intervals, and to examine specific neural and muscular mechanisms contributing to these differences. METHODS: Thirty-two young (20.0±2.1 yrs) and 20 older (69.5±3.3 yrs) recreationally active men performed rapid plantarflexion isometric muscle actions to examine absolute and normalized RTD and muscle activation using electromyography (EMG) at early and late time intervals...
February 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28160715/study-of-adsorption-characteristics-of-au-iii-onto-coal-particles-and-their-application-as-radiotracer-in-a-coal-gasifier
#9
Sunil Goswami, Harish Jagat Pant, Rajwardhan Nandram Ambade, Bhasakar Paul, Lalit Varshney, Ashutosh Dash
This paper describes a systematic study carried out to investigate adsorption characteristics of (198)Au onto the surface of coal particles using a radiotracer technique. The main objective of the study was to optimize labeling conditions and utilize the labeled coal particles as a radiotracer for tracing coal particles in fluidized bed coal gasifiers. The effect of various experimental factors such as pH, amount of adsorbent, initial gold concentration, temperature and contact time between adsorbate and adsorbent were studied to obtain optimum conditions for maximum adsorption of (198)Au on coal particles from an aqueous solution...
January 16, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28151653/full-sequence-amino-acid-scanning-of-%C3%AE-defensin-rtd-1-yields-a-potent-anthrax-lethal-factor-protease-inhibitor
#10
Yilong Li, Andrew Gould, Teshome Aboye, Tao Bi, Leonard Breindel, Alexander Shekhtman, Julio A Camarero
θ-Defensin RTD-1 is a noncompetitive inhibitor of anthrax lethal factor (LF) protease (IC50 = 390 ± 20 nM, Ki = 365 ± 20 nM) and a weak inhibitor of other mammalian metalloproteases such as TNFα converting enzyme (TACE) (Ki = 4.45 ± 0.48 μM). Using full sequence amino acid scanning in combination with a highly efficient "one-pot" cyclization-folding approach, we obtained an RTD-1-based peptide that was around 10 times more active than wild-type RTD-1 in inhibiting LF protease (IC50 = 43 ± 3 nM, Ki = 18 ± 1 nM)...
February 14, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28149337/explosive-strength-of-the-knee-extensors-the-influence-of-criterion-trial-detection-methodology-on-measurement-reproducibility
#11
Johannes Dirnberger, Hans-Peter Wiesinger, Nicolas Wiemer, Alexander Kösters, Erich Müller
The present study was conducted to assess test-retest reproducibility of explosive strength measurements during single-joint isometric knee extension using the IsoMed 2000 dynamometer. Thirty-one physically active male subjects (mean age: 23.7 years) were measured on two occasions separated by 48-72 h. The intraclass correlation coefficient (ICC 2,1) and the coefficient of variation (CV) were calculated for (i) maximum torque (MVC), (ii) the peak rate of torque development (RTDpeak) as well as for (iii) the average rate of torque development (RTD) and the impulse taken at several predefined time intervals (0-30 to 0-300 ms); thereby explosive strength variables were derived in two conceptually different versions: on the one hand from the MVC-trial (version I), on the other hand from the trial showing the RTDpeak (version II)...
April 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28121802/delayed-effect-of-blood-flow-restricted-resistance-training-on-rapid-force-capacity
#12
Jakob Lindberg Nielsen, Ulrik Frandsen, Tatyana Prokhorova, Rune Dueholm Bech, Tobias Nygaard, Charlotte Suetta, Per Aagaard
PURPOSE: The aim of the present study was to investigate the effect and time course of high-frequent low-load resistance training with blood-flow restriction (BFR) on rapid force capacity (i.e. rate of torque development (RTD)). METHODS: Ten male subjects (22.8±2.3 years) performed four sets of knee extensor exercise (20%1RM) to concentric failure during concurrent BFR of the thigh (100mmHg), while eight work-matched controls (21.9±3.0 years) trained without BFR (CON)...
January 23, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28110327/mortality-after-renal-allograft-failure-and-return-to-dialysis
#13
Amarpali Brar, Mariana Markell, Dimitre G Stefanov, Edem Timpo, Rahul M Jindal, Robert Nee, Nabil Sumrani, Devon John, Fasika Tedla, Moro O Salifu
INTRODUCTION: The outcomes of patients who fail their kidney transplant and return to dialysis (RTD) has not been investigated in a nationally representative sample. We hypothesized that variations in management of transplant chronic kidney disease stage 5 leading to kidney allograft failure (KAF) and RTD, such as access, nutrition, timing of dialysis, and anemia management predict long-term survival. METHODS: We used an incident cohort of patients from the United States Renal Data System who initiated hemodialysis between January 1, 2003 and December 31, 2008, after KAF...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28101487/immunoglobulin-g4-related-thyroid-diseases
#14
REVIEW
Dulani Kottahachchi, Duncan J Topliss
Immunoglobulin G4-related disease (IgG4-RD) is a new disease category involving many organ systems, including the endocrine system in general and the thyroid in particular. Since an initial association was made between hypothyroidism and autoimmune (IgG4-related) pancreatitis, more forms of IgG4-related thyroid disease (IgG4-RTD) have been recognized. Four subcategories of IgG4-RTD have so far been identified: Riedel thyroiditis (RT), fibrosing variant of Hashimoto thyroiditis (FVHT), IgG4-related Hashimoto thyroiditis, and Graves disease with elevated IgG4 levels...
December 2016: European Thyroid Journal
https://www.readbyqxmd.com/read/28101403/quantitative-assessment-of-hemodynamic-and-structural-characteristics-of-in-vivo-brain-tissue-using-total-diffuse-reflectance-spectrum-measured-in-a-non-contact-fashion
#15
Yinchen Song, Sarahy Garcia, Yisel Frometa, Jessica C Ramella-Roman, Mohammad Soltani, Mohamed Almadi, Jorge J Riera, Wei-Chiang Lin
Here we present a new methodology that investigates the intrinsic structural and hemodynamic characteristics of in vivo brain tissue, in a non-contact fashion, and can be easily incorporated in an intra-operative environment. Within this methodology, relative total diffuse reflectance spectra (RTD(λ)) were acquired from targets using a hybrid spectroscopy imaging system. A spectral interpretation algorithm was subsequently applied to RTD(λ) to retrieve optical properties related to the compositional and structural characteristics of each target...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28069390/continuous-direct-compression-as-manufacturing-platform-for-sustained-release-tablets
#16
B Van Snick, J Holman, C Cunningham, A Kumar, J Vercruysse, T De Beer, J P Remon, C Vervaet
This study presents a framework for process and product development on a continuous direct compression manufacturing platform. A challenging sustained release formulation with high content of a poorly flowing low density drug was selected. Two HPMC grades were evaluated as matrix former: standard Methocel CR and directly compressible Methocel DC2. The feeding behavior of each formulation component was investigated by deriving feed factor profiles. The maximum feed factor was used to estimate the drive command and depended strongly upon the density of the material...
March 15, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28033501/investigation-of-holdup-and-axial-dispersion-of-liquid-phase-in-a-catalytic-exchange-column-using-radiotracer-technique
#17
Rajesh Kumar, H J Pant, Sunil Goswami, V K Sharma, A Dash, S Mishra, K Bhanja, Sadhana Mohan, S M Mahajani
Holdup and axial dispersion of liquid phase in a catalytic exchange column were investigated by measuring residence time distributions (RTD) using a radiotracer technique. RTD experiments were independently carried out with two different types of packings i.e. hydrophobic water-repellent supported platinum catalyst and a mixture (50% (v/v)) of hydrophobic catalyst and a hydrophillic wettable packing were used in the column. Mean residence times and hold-ups of the liquid phase were estimated at different operating conditions...
March 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/27994858/renal-tubular-dysgenesis-antenatal-ultrasound-scanning-and-molecular-investigations-in-a-saudi-arabian-family
#18
Mohamed H Al-Hamed, Wesam Kurdi, Nada Alsahan, Qaamariya Ambosaidi, Maha Tulbah, John A Sayer
Autosomal recessive renal tubular dysgenesis (RTD) is a rare lethal disease affecting renal development before birth. RTD is manifested by anuria and severe hypotension resulting in oligohydramnios and birth defects known as Potter's syndrome. Homozygous or compound heterozygous mutations in genes encoding components of the renin-angiotensin system (ACE, AGT, AGTR1 and REN) have been reported to cause RTD. A consanguineous family with a history of multiple stillbirths was investigated using prenatal ultrasound and molecular genetic analysis of an affected foetus...
December 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27990798/poly-ethylene-glycol-crowding-as-critical-factor-to-determine-pdna-packaging-scheme-into-polyplex-micelles-for-enhanced-gene-expression
#19
Kaori M Takeda, Kensuke Osada, Theofilus A Tockary, Anjaneyulu Dirisala, Qixian Chen, Kazunori Kataoka
A critical role of polyethylene glycol (PEG) crowding in the packaging of plasmid DNA (pDNA) into polyplex micelles (PMs) was investigated using a series of PEG-b-poly(l-lysine) (PEG-PLys) block copolymers with varying molecular weights of both PEG and PLys segments. Rod-shaped PMs preferentially formed when the tethered PEG chains covering pDNA in a precondensed state were dense enough to overlap one another (reduced tethering density (RTD) > 1), whereas globular PMs were obtained when they were not overlapped (RTD < 1)...
December 19, 2016: Biomacromolecules
https://www.readbyqxmd.com/read/27941163/effects-of-accumulating-work-shifts-on-performance-based-fatigue-using-multiple-strength-measurements-in-day-and-night-shift-nurses-and-aides
#20
Brennan J Thompson, Matt S Stock, Victoria K Banuelas
OBJECTIVE: This study aimed to examine the effects of accumulating nursing work on maximal and rapid strength characteristics in female nurses and compare these effects in day versus night shift workers. BACKGROUND: Nurses exhibit among the highest nonfatal injury rates of all occupations, which may be a consequence of long, cumulative work shift schedules. Fatigue may accumulate across multiple shifts and lead to performance impairments, which in turn may be linked to injury risks...
December 9, 2016: Human Factors
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